Tolinapant and Radiation for Cisplatin-Ineligible, Previously Untreated, Locally Advanced Head and Neck Cancer
Conditions:   Head and Neck Carcinoma of Unknown Primary;   Locally Advanced Head and Neck Squamous Cell Carcinoma;   Locally Advanced Hypopharyngeal Squamous Cell Carcinoma;   Locally Advanced Laryngeal Squamous Cell Carcinoma;   Locally Advanced Nasopharyngeal Squamous Cell Carcinoma;   Locally A dvanced Oropharyngeal Squamous Cell Carcinoma Interventions:   Drug: Tolinapant;   Radiation: Radiation Therapy Sponsors:   Emory University;   Astex Pharmaceuticals, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 18, 2022 Category: Research Source Type: clinical trials

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Stage III-IVB Head and Neck Cancer
Conditions:   Head and Neck Carcinoma of Unknown Primary;   Locally Advanced Head and Neck Squamous Cell Carcinoma;   Locally Advanced Hypopharyngeal Squamous Cell Carcinoma;   Locally Advanced Laryngeal Squamous Cell Carcinoma;   Locally Advanced Oral Cavity Squamous Cell Carcinoma;   Locally Adva nced Oropharyngeal Squamous Cell Carcinoma;   Locally Advanced Sinonasal Squamous Cell Carcinoma;   Maxillary Sinus Squamous Cell Carcinoma;   Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8;   Stage III Hypopharyngeal Carcinoma AJCC v8;   Stage III Laryngeal  Cancer AJCC v...
Source: ClinicalTrials.gov - December 29, 2021 Category: Research Source Type: clinical trials

Induction Chemotherapy and Toripalimab for Larynx Preservation in Resectable Laryngeal/Hypopharyngeal Carcinoma
Conditions:   Laryngeal Cancer;   Hypopharynx Cancer;   Laryngeal Neoplasms Intervention:   Drug: chemotherapy TP regimen combined with Toripalimab Sponsor:   Fudan University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 6, 2021 Category: Research Source Type: clinical trials