HBO regulates the Warburg effect of hypoxic HCC cells through miR-103a-3p/TRIM35
ConclusionThese findings reveal that HBO regulates the Warburg effect of hypoxic HCC cells through miR-103a-3p/TRIM35 and inhibits tumor growth. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 20, 2024 Category: Cancer & Oncology Source Type: research
The synergistic potential of hydrogen inhalation and hyperbaric oxygen therapy
We read with great interest the review by Lee and colleagues, in which the authors describe the use of hyperbaric oxygen therapy (HBOT) as a novel adjunctive treatment to standard treatment for spinal cord injury (SCI) after complex aortic repair (CAR).1 HBOT is a revolutionary therapy for many postsurgical complications such as SCI after CAR. We are curious to know if the authors considered hydrogen inhalation therapy (HIT) in combination with HBOT. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - April 18, 2024 Category: Surgery Authors: Michael G. James, Viren S. Sehgal Tags: Letter to the Editor Source Type: research
Current knowledge of ferroptosis in the pathogenesis and prognosis of oral squamous cell carcinoma
In this study, we performed a first attempt to collect the current evidence on the proposed roles of ferroptosis in OSCC through a comprehensive review. Based on clinical data from the relevant studies within this topic, we found that ferroptosis-associated tumor microenvironment, ferroptosis-related genes (FRGs), and ferroptosis-related lncRNAs exhibited a potent prognostic value for OSCC patients. Mechanistically, experimental data revealed that the proliferation and tumorigenesis of OSCC might be associated with the inhibition of cellular ferroptosis through the activation of glutathione peroxidase 4 (GPX4) and adipocyt...
Source: Cellular Signalling - April 18, 2024 Category: Cytology Authors: Liyuan Zhou Youjun Wu Yukang Ying Yan Ding Source Type: research
Risk factors and predictive models for sequelae of heat stroke primarily involving cerebellar dysfunction
Volume 34, Issue 1, February 2024, Page 1-14 . (Source: Critical Public Health)
Source: Critical Public Health - April 18, 2024 Category: International Medicine & Public Health Authors: Xiao-Xiao NiGai-Ci XueYe-Qun GuoXiao-Juan XieJie WangZhi-Feng Liua Department of Hyperbaric Oxygen Medicine and Rehabilitation, General Hospital of Southern Theater Command of PLA, Guangzhou, Guangdong, Chinab Department of Neurosurgery, General Hospital Source Type: research
Outcomes after pancreaticoduodenectomy with or without preoperative hyperbaric oxygen therapy
CONCLUSIONS: Preoperative HBO2 did not affect perioperative outcomes or significantly change the inflammatory mediators for patients undergoing robotic pancreaticoduodenectomy. Long-term survival was inferior after preoperative HBO2. Further randomized controlled studies are required to assess the full impact of this treatment on patients' prognosis.PMID:38615348 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Harel Jacoby Enrico M Camporesi Sharona B Ross Iswanto Sucandy Gerardo Bosco Cameron Syblis Kaitlyn Crespo Alexander Rosemurgy Source Type: research
Transcutaneous oximetry values in chronic ulcer patients during Hyperbaric treatment at 1.4 ATA compared to 2 ATA
Undersea Hyperb Med. 2024 First Quarter;51(1):1-5.ABSTRACTChronic wounds have a significant impact on a patient's quality of life. Different pathologies, such as poor blood supply and tissue breakdown, may lead to inadequate oxygenation of the wound. Hyperbaric oxygen (HBO2) is a widely used treatment for an increasing number of medical practices. A new so-called "hyperbaric treatment" trend has emerged. The use of low-pressure, soft-sided, or inflatable chambers represents a growing trend in hyperbaric medicine. Used in professional settings as well as directly marketed to individuals for home use, they are promoted as eq...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Ram A Sack Yoav Yechezkel Pikkel Ortal Leitner Shemy Yitzhak Ramon Yehuda Ullmann Assaf A Zeltzer Source Type: research
Pneumothorax during manned chamber operations: A summary of reported cases
Undersea Hyperb Med. 2024 First Quarter;51(1):29-35.ABSTRACTIn-chamber pneumothorax has complicated medically remote professional diving operations, submarine escape training, management of decompression illness, and hospital-based provision of hyperbaric oxygen therapy. Attempts to avoid thoracotomy by combination of high oxygen partial pressure breathing (the concept of inherent unsaturation) and greatly slowed rates of chamber decompression proved successful on several occasions. When this delicate balance designed to prevent the intrapleural gas volume from expanding faster than it contracts proved futile, chest drains...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Medical and surgical management of pneumothorax in diving and hyperbaric chambers
Undersea Hyperb Med. 2024 First Quarter;51(1):17-28.ABSTRACTThe presence of a pneumothorax within a pressurized chamber represents unique diagnostic and management challenges. This is particularly the case in the medical and geographic remoteness of many chamber locations. Upon commencing chamber decompression, unvented intrapleural air expands. If its initial volume and/or degree of chamber pressure reduction is significant enough, a tension pneumothorax will result. Numerous reports chronicle failure to diagnose and manage in-chamber pneumothorax with resultant morbidity and one fatal outcome. Such cases have occurred in...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Richard E Clarke Keith Van Meter Source Type: research
Barodontalgia during hyperbaric oxygen therapy of an 8-year-old male: A case report
In conclusion, caries lesions and faulty restorations should be examined before hyperbaric oxygen therapy sessions. Even though barodontalgia is a rare phenomenon, dental examination is essential to avoid these kinds of pain-related complications. All carious lesions and defective restorations must be treated, if necessary. Removal of faulty restorations and management of inflammation as part of the treatment is suggested before exposure to pressure changes.PMID:38615353 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Melisa Öçbe Selin Gamze S ümen B üşra Dilara Altun Asim Dumlu Source Type: research
Chondronecrosis of the cricoid treated with hyperbaric oxygen therapy: A case series
We present two cases of cricoid chondronecrosis treated with hyperbaric oxygen (HBO2) therapy. Both patients presented with biphasic stridor and dyspnea several weeks after an intubation event. Tracheostomy was ultimately performed for airway protection, followed by antibiotic treatment and outpatient HBO2 therapy. Both patients were decannulated within six months of presentation and after at least 20 HBO2 therapy sessions. Despite a small sample size, our findings are consistent with data supporting HBO2 therapy's effects on tissue edema, neovascularization, and HBO2 potentiation of antibiotic treatment and leukocyte func...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: John David Spencer Tyler Connely Jeffrey Cooper Jayme Rose Dowdall Source Type: research
Surviving cardiac arrest after carbon monoxide poisoning treated with hyperbaric oxygen therapy
Undersea Hyperb Med. 2024 First Quarter;51(1):37-40.ABSTRACTCarbon monoxide (CO) and cyanide poisoning are frequent causes of morbidity and mortality in cases of house and industrial fires. The 14th edition of guidelines from the Undersea and Hyperbaric Medical Society does not recommend hyperbaric oxygen (HBO2) treatment in those patients who have suffered a cardiac arrest and had to receive cardiopulmonary resuscitation. In this paper, we describe the case of a 31-year-old patient who received HBO2 treatment in the setting of cardiac arrest and survived.PMID:38615351 (Source: Undersea and Hyperbaric Medicine)
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Vladimir Bronshteyn Stephen M Hendriksen Samantha J Lee Christopher Logue Source Type: research
Decompression sickness followed by diabetic ketoacidosis and sepsis shock: an unusual case report
Undersea Hyperb Med. 2024 First Quarter;51(1):41-46.ABSTRACTDecompression sickness (DCS) is caused by abrupt changes in extracorporeal pressure with varying severity. Symptoms range from mild musculoskeletal pain to severe organ dysfunction and death, especially among patients with chronic underlying disease. Here, we report an unusual case of a 49-year-old man who experienced DCS after a dive to a depth of 38 meters. The patient's symptoms progressed, starting with mild physical discomfort that progressed to disturbance of consciousness on the second morning. During hospitalization, we identified that in addition to DCS, ...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Anwei Liu Xiaogan Hou Jing Nie Qiang Wen Zhiguo Pan Source Type: research
Physical and Physiological Predictors Determining the Maximal Static Apnea Diving Time of Male Freedivers
This study aimed to investigate what factors determine freedivers' maximal static apnea dive time. We correlated some physical/physiological factors with male freedivers' maximum apnea diving duration. Thirty-six experienced male freedivers participated in this study. The divers participated in two days of the experiments. On the first day, apnea diving time, blood oxygen saturation (SpO2), heart rate (HR), blood pressure (BP), stress index, and blood parameters were measured before, during, and after the apnea diving in the pool. On the second day, body composition, lung capacity, resting and maximal oxygen consumption (V...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Dai-Woo Lee Hongwei Yang Jeong-Sun Ju Source Type: research
Physical and Physiological Predictors Determining the Maximal Static Apnea Diving Time of Male Freedivers
This study aimed to investigate what factors determine freedivers' maximal static apnea dive time. We correlated some physical/physiological factors with male freedivers' maximum apnea diving duration. Thirty-six experienced male freedivers participated in this study. The divers participated in two days of the experiments. On the first day, apnea diving time, blood oxygen saturation (SpO2), heart rate (HR), blood pressure (BP), stress index, and blood parameters were measured before, during, and after the apnea diving in the pool. On the second day, body composition, lung capacity, resting and maximal oxygen consumption (V...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: Dai-Woo Lee Hongwei Yang Jeong-Sun Ju Source Type: research
Chondronecrosis of the cricoid treated with hyperbaric oxygen therapy: A case series
We present two cases of cricoid chondronecrosis treated with hyperbaric oxygen (HBO2) therapy. Both patients presented with biphasic stridor and dyspnea several weeks after an intubation event. Tracheostomy was ultimately performed for airway protection, followed by antibiotic treatment and outpatient HBO2 therapy. Both patients were decannulated within six months of presentation and after at least 20 HBO2 therapy sessions. Despite a small sample size, our findings are consistent with data supporting HBO2 therapy's effects on tissue edema, neovascularization, and HBO2 potentiation of antibiotic treatment and leukocyte func...
Source: Undersea and Hyperbaric Medicine - April 14, 2024 Category: Sports Medicine Authors: John David Spencer Tyler Connely Jeffrey Cooper Jayme Rose Dowdall Source Type: research
