Alternative routine for reporting chiral amphetamine test results in assessment of attention ‐deficit/hyperactivity disorder medication: experiences from 2013 to 2023
In conclusion, this study demonstrated the clinical value and utility of a new routine for reporting urinary chiral amphetamine results to differentiate adherence to ADHD medication from illicit drug use. Unlike thel/d-amphetamine ratio, it considers differences in total amphetamine concentration and urine dilution, factors that can affect the interpretation. (Source: Drug Testing and Analysis)
Source: Drug Testing and Analysis - April 11, 2024 Category: Drugs & Pharmacology Authors: Anders Helander, Annika Andersson, Tomas Vill én Tags: RESEARCH ARTICLE Source Type: research

An updated review on animal models to study attention-deficit hyperactivity disorder
Translational Psychiatry, Published online: 11 April 2024; doi:10.1038/s41398-024-02893-0An updated review on animal models to study attention-deficit hyperactivity disorder (Source: Translational Psychiatry)
Source: Translational Psychiatry - April 11, 2024 Category: Psychiatry Authors: Daegeon Kim Dhananjay Yadav Minseok Song Source Type: research

Cortico-striatal differences in the epigenome in attention-deficit/ hyperactivity disorder
Translational Psychiatry, Published online: 11 April 2024; doi:10.1038/s41398-024-02896-xCortico-striatal differences in the epigenome in attention-deficit/ hyperactivity disorder (Source: Translational Psychiatry)
Source: Translational Psychiatry - April 11, 2024 Category: Psychiatry Authors: Gauri G. Shastri Gustavo Sudre Kwangmi Ahn Benjamin Jung Bhaskar Kolachana Pavan K. Auluck Laura Elnitski Stefano Marenco Philip Shaw Source Type: research

From the Editor-in-Chief's Desk: Advances in Patient-Centered Treatment for Attention-Deficit/Hyperactivity Disorder
Journal of Child and Adolescent Psychopharmacology,Volume 34, Issue 3, Page 117-118, April 2024. (Source: Journal of Child and Adolescent Psychopharmacology)
Source: Journal of Child and Adolescent Psychopharmacology - April 11, 2024 Category: Pediatrics Authors: Paul E. Croarkin Source Type: research

Adult Attention Deficit –Hyperactivity Disorder is associated with Lewy body disease and cognitive impairment. A prospective cohort study with 15-year follow-up.
Attention-deficit hyperactivity disorder (ADHD) is one of the most common behavioral disorders in child and adolescent psychiatry. This disorder affects from 5.9% to 7.1% of children and adolescents according to meta-analytical results depending on the source of information for the diagnosis (1). ADHD is characterized by impaired attentional functions, hyperactivity, and increased Impulsivity (2). (Source: The American Journal of Geriatric Psychiatry)
Source: The American Journal of Geriatric Psychiatry - April 10, 2024 Category: Geriatrics Authors: Ángel Golimstok, María José García Basalo, Mariana Majul, Waleska Berrios, Marcelo Rugiero, Maria Cecilia Fernández, Roni Eichel Source Type: research

Adult-Onset Attention Deficit –Hyperactivity Disorder and the Risk of Lewy Body Dementia: An Invited Commentary
Little is known about adult-onset Attention-Deficit/Hyperactivity Disorder (ADHD). However, evidence exists to suggest that it is distinct from childhood-onset ADHD.1 Adult-onset ADHD, with a prevalence rate of 3%, is characterized by symptoms of inattention or hyperactivity (or impulsivity) but also by elevated cognitive complaints,1 suggesting a plausible link to neurodegeneration. Indeed, prior studies have shown a link between adult-onset ADHD and an increased risk of neurodegenerative disease,2 particularly dementia. (Source: The American Journal of Geriatric Psychiatry)
Source: The American Journal of Geriatric Psychiatry - April 10, 2024 Category: Geriatrics Authors: Anat Rotstein Tags: Editorial Source Type: research

Impact of Viloxazine Extended-Release Capsules (Qelbree ®) on Select Cytochrome P450 Enzyme Activity and Evaluation of CYP2D6 Genetic Polymorphisms on Viloxazine Pharmacokinetics
ConclusionViloxazine ER is a strong CYP1A2 inhibitor and a weak CYP2D6 and CYP3A4 inhibitor. CYP2D6 polymorphisms did not meaningfully alter the viloxazine ER pharmacokinetic profile. (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - April 10, 2024 Category: Drugs & Pharmacology Source Type: research

Identifying Risk Factors for Attention-Deficit/Hyperactivity Disorder (ADHD): a Public Health Concern and Opportunity
AbstractAttention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders with significant individual and societal negative impacts of the disorder continuing into adulthood (Danielson et al. in  Journal of Clinical Child and Adolescent Psychology,in press; Landes and London in Journal of Attention Disorders 25:3 –13,2021). Genetic and environmental risk (e.g., modifiable exposures such as prenatal tobacco exposure and child maltreatment) for ADHD is likely multifactorial (Faraone et al. in Neuroscience& Biobehavioral Reviews 128:789 –818,2021). However, the evidence for potent...
Source: Prevention Science - April 10, 2024 Category: Psychiatry & Psychology Source Type: research

Maternal asthma and asthma exacerbation during pregnancy and attention-deficit/hyperactivity disorder in offspring: a population-based cohort study
AbstractThe link between inflammatory disorders, such as asthma, and attention deficit hyperactivity disorder (ADHD) is attracting increasing attention but few studies have examined cross-generational associations. We sought to examine associations of maternal asthma and asthma exacerbation during pregnancy, as well as paternal asthma, with the risk of ADHD in children. This population-based cohort study used data from the Taiwan National Health Insurance Research Database from 2004 to 2017. Cox regression models compared the risk of ADHD in children of parents with and without asthma, adjusting for parental sociodemograph...
Source: European Child and Adolescent Psychiatry - April 10, 2024 Category: Psychiatry Source Type: research

Identifying Risk Factors for Attention-Deficit/Hyperactivity Disorder (ADHD): a Public Health Concern and Opportunity
AbstractAttention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders with significant individual and societal negative impacts of the disorder continuing into adulthood (Danielson et al. in  Journal of Clinical Child and Adolescent Psychology,in press; Landes and London in Journal of Attention Disorders 25:3 –13,2021). Genetic and environmental risk (e.g., modifiable exposures such as prenatal tobacco exposure and child maltreatment) for ADHD is likely multifactorial (Faraone et al. in Neuroscience& Biobehavioral Reviews 128:789 –818,2021). However, the evidence for potent...
Source: Prevention Science - April 10, 2024 Category: Psychiatry & Psychology Source Type: research

Roadside experiences of parents of children with developmental coordination disorder and/or attention deficit hyperactivity disorder
DiscussionWhile there were commonalities in the challenges faced by children with DCD and/or ADHD at the roadside, there were also notable differences. Parents of children with DCD discussed challenges with spatial awareness and motor skills, whereas parents of children with ADHD discussed challenges with impulsivity and inattention. Parents of children with co-occurring DCD and ADHD described a complex interplay of these challenges. It is evident from the interviews that children with DCD and/or ADHD require a distinct approach to develop their pedestrian skills effectively and parents reported specific strategies they us...
Source: Frontiers in Human Neuroscience - April 10, 2024 Category: Neuroscience Source Type: research

Gabor filter-based statistical features for ADHD detection
Attention deficit/hyperactivity disorder (ADHD) is a neuropsychological disorder that occurs in children and is characterized by inattention, impulsivity, and hyperactivity. Early and accurate diagnosis of ADHD is very important for effective intervention. The aim of this study is to develop a computer-aided approach to detecting ADHD using electroencephalogram (EEG) signals. Specifically, we explore a Gabor filter-based statistical features approach for the classification of EEG signals into ADHD and healthy control (HC). The EEG signal is processed by a bank of Gabor filters to obtain narrow-band signals. Subsequently, a...
Source: Frontiers in Human Neuroscience - April 10, 2024 Category: Neuroscience Source Type: research

Study Finds No Link Between Acetaminophen Use During Pregnancy And Autism, ADHD Risk
Children exposed to acetaminophen in the womb do not appear to have an increased risk of autism or attention-deficit/hyperactivity disorder (ADHD), according to a studypublished today inJAMA. While a broad analysis of Swedish families found a slightly increased rate of these disorders in children exposed to acetaminophen in the womb, the researchers found no evidence acetaminophen was responsible when factoring in genetic or family influence.“Results of this study indicate that the association between acetaminophen use during pregnancy and neurodevelopmental disorders is a noncausal association.,” wrote Viktor H. Ahlqv...
Source: Psychiatr News - April 9, 2024 Category: Psychiatry Tags: acetaminophen ADHD attention deficit hyperactivity disorder autism JAMA pregnancy risk factor Sweden Tylenol Source Type: research

Metal nanoparticle-induced effects on green toads (Amphibia, Anura) under climate change: conservation implications
In this study, we investigated the survival, developmental, behavioral, and histological reactions of Bufotes viridis embryos and larvae exposed to different NPs for a duration of 10 days, using lethal concentrations (LC25%, LC50%, and LC75% mg/L) under both ambient (AT: 18 °C) and high (HT: 21 °C) temperatures. Based on LC, NiONPs > ZnONPs > CuONPs > Al2O3NPs > TiO2NPs > Fe3O4NPs showed the highest mortality at AT. A similar pattern was observed at HT, although mortality occurred at lower concentrations and Fe3O4NPs were more toxic than TiO2NPs. The results indicated that increasing concentrations of NPs ...
Source: Environmental Science and Pollution Research International - April 9, 2024 Category: Environmental Health Authors: Somaye Vaissi Azam Chahardoli Zahra Minoosh Siavosh Haghighi Pouria Heshmatzad Source Type: research

Integrating Structural and Experiential Family Therapy in Neurodivergent Families: A Case Study
Issues Ment Health Nurs. 2024 Apr 9:1-11. doi: 10.1080/01612840.2024.2328260. Online ahead of print.ABSTRACTAutism Spectrum Disorder (ASD) is widely regarded as the most severe childhood behavioral disorder. However, society's lack of awareness regarding neurodevelopmental disorders, like autism, has led to a limited understanding of their profound impact on children and their families. Challenges include unique sensory experiences, communication and social interactions, strain on familial relationships, emotional toll on parents, and educational hurdles, which can significantly impact the well-being of individuals and the...
Source: Issues in Mental Health Nursing - April 9, 2024 Category: Nursing Authors: Annemarie Sohn Ma Jixuan Zhao Lmsw Eman Tadros PhD Lmft Source Type: research