VITAMINS trial report on vitamin C, hydrocortisone, thiamine for septic shock
(JAMA Network) In this randomized clinical trial of about 200 patients with septic shock, combination treatment with intravenous vitamin C, hydrocortisone and thiamine compared with intravenous hydrocortisone alone didn't significantly improve the amount of time patients were alive and free of medicines that raise blood pressure (vasopressors) over seven days. The study findings are being released to coincide with presentation at the Critical Care Reviews Meeting 2020 in Belfast, Northern Ireland. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 17, 2020 Category: International Medicine & Public Health Source Type: news
pramoxine and hydrocortisone (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC)
Title: pramoxine and hydrocortisone (Epifoam, Pramosone, Proctofoam HC, Procort, Analpram HC)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 11/22/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - November 22, 2019 Category: Dermatology Source Type: news
Vitamin C and Thiamine for Sepsis and Septic Shock
Sepsis and septic shock are medical emergencies resulting in significant morbidity and mortality. Intravenous (IV) vitamin C, thiamine, and hydrocortisone have shown promise in reducing hospital mortality. The Memphis Veterans Affairs Medical Center (VAMC) similarly implemented this regimen, called the vitamin C protocol, for patients presenting in sepsis or septic shock in the intensive care unit (ICU). Although no significant mortality benefit was observed, the vitamin C protocol was not associated with patient harm. In this Veteran population, there was reduced ICU length of stay, suggesting possible benefit. Th...
Source: Current Awareness Service for Health (CASH) - September 19, 2019 Category: Consumer Health News Source Type: news
Vytone (Hydrocortisone Acetate, USP 1.9%, Iodoquinol, USP 1%) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 17, 2019 Category: Drugs & Pharmacology Source Type: news
Protopic Ointment vs. Hydrocortisone
Title: Protopic Ointment vs. HydrocortisoneCategory: MedicationsCreated: 8/12/2019 12:00:00 AMLast Editorial Review: 8/12/2019 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - August 12, 2019 Category: Dermatology Source Type: news
Lucky Mart Inc. Issues Voluntary Nationwide Recall Of Piyanping Anti-Itch Lotion Due to Incorrect Active Ingredient
Lucky Mart Inc. is voluntarily recalling lots C14005, C16001 and C16002 of Piyanping Anti-Itch Lotion to the consumer level. The product was manufactured using the active pharmaceutical ingredient dexamethasone rather than hydrocortisone. Dexamethasone is not listed as an ingredient in the labeling. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 24, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news
Impact of CBG Circadian Rhythm on Cortisol Exposure Impact of CBG Circadian Rhythm on Cortisol Exposure
How does the circadian rhythm of CBG impact cortisol exposure after hydrocortisone administration?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 17, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
How to treat wounds caused by insects and animal bites
Being outdoors during the warm weather season carries with it the risk of bites of all kinds – insects, animals, ticks and others. Here is some helpful advice for treating bites and itching.
Check the symptoms. Most insect bites and stings are mild, causing minor symptoms like itching, redness, stinging or a small degree of swelling around the bite. In some rare cases, stings from hornets, bees, wasps, scorpions or fire ants may lead to more serious reactions, including mosquito-borne West Nile virus. The Mayo Clinic advises moving away from the area where you were stung or bitten to prevent further injury. T...
Source: Advanced Tissue - June 10, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound care products wound care treatment Source Type: news
Traumatic imagery following glucocorticoid administration in earthquake-related post-traumatic stress disorder: a preliminary functional magnetic resonance imaging study - Douglas KM, Groves S, Porter RJ, Jordan J, Wilson L, Melzer TR, Wise RG, Bisson JI, Bell CJ.
OBJECTIVE: Post-traumatic stress disorder involves excessive retrieval of traumatic memories. Glucocorticoids impair declarative memory retrieval. This preliminary study examined the effect of acute hydrocortisone administration on brain activation in indi... (Source: SafetyLit)
Source: SafetyLit - June 4, 2019 Category: International Medicine & Public Health Tags: Disaster Preparedness Source Type: news
Vitamin C, Hydrocortisone, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Analysis of Real-World Application
A recent study suggested mortality benefits using vitamin C, hydrocortisone, and thiamine combination therapy (triple therapy) in addition to standard care in patients with severe sepsis and septic shock. In order to further evaluate the effects of triple therapy in real-world clinical practice, we conducted a retrospective observational cohort study at an academic tertiary care hospital. When compared to standard care, triple therapy did not improve hospital or ICU mortality in patients with septic shock. A randomized controlled trial evaluating the effects of triple therapy is necessary prior to implementing vita...
Source: Current Awareness Service for Health (CASH) - May 29, 2019 Category: Consumer Health News Source Type: news
Essential wound care supplies for your home first aid kit
When the cut, scrape, blister or bleeding happens, you don't want to be stuck running in a panicked frenzy to the closest drug store. Instead, be prepared for common injuries, symptoms and ailments with a well-stocked medicine cabinet and home first aid kit.
Here are the essential wound care supplies you should have on hand at home:
Make sure your home first aid kit is well stocked.
For cuts and scrapes:
The basic must-haves for these minor wounds include:
Adhesive bandages in various sizes.
Sterile gauze pads.
Medical tape.
Antibiotic ointment.
The size of the wound will help you determine whether a bandage will s...
Source: Advanced Tissue - April 29, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound care products Source Type: news
Hydrocortisone Tablets, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - April 19, 2019 Category: Drugs & Pharmacology Source Type: news
Hydrocortisone Does Not Reduce BPD in Preemies Hydrocortisone Does Not Reduce BPD in Preemies
Systemic hydrocortisone did not reduce the risk for a composite endpoint of death or bronchopulmonary dysplasia in very preterm infants receiving mechanical ventilation, a randomized trial found.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 30, 2019 Category: Consumer Health News Tags: Pediatrics News Source Type: news
Hydrocortisone, Ascorbic Acid and Thiamine (HAT Therapy) for the Treatment of Sepsis. Focus on Ascorbic Acid
The authors of this journal article state that sepsis is a devastating disease that carries an enormous toll in terms of human suffering and lives lost. They say that over 100 novel pharmacologic agents that targeted specific molecules or pathways have failed to improve the outcome of sepsis. Preliminary data suggests that the combination of Hydrocortisone, Ascorbic Acid and Thiamine (HAT therapy) may reduce organ failure and mortality in patients with sepsis and septic shock. HAT therapy is based on the concept that a combination of readily available, safe and cheap agents, which target multiple components of the host ' s...
Source: Current Awareness Service for Health (CASH) - December 28, 2018 Category: Consumer Health News Source Type: news
Hydrocortisone muco-adhesive buccal tablets
should not be used off-label for treating adrenal insufficiency in children due to serious risks. There is a risk of insufficient cortisol absorption and li (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - December 19, 2018 Category: Drugs & Pharmacology Source Type: news
