Two types of steroid found to save lives of some Covid-19 patients
Analysis of seven trials finds dexamethasone and hydrocortisone should be given in severe casesCoronavirus – latest updatesSee all our coronavirus coverageStudies around the world have confirmed that steroids can save lives in the Covid-19 pandemic, leading to new recommendations from the World Heath Organization that doctors should give them to severely ill patients.In June, the Recovery trial run in most NHS hospitals and led by Oxford University found that the lives of one in eight people sick enough from Covid-19 to need a ventilator could be saved by a steroid called dexamethasone.Continue reading... (Source: Guardi...
Source: Guardian Unlimited Science - September 2, 2020 Category: Science Authors: Sarah Boseley Health editor Tags: Medical research Coronavirus outbreak Science World news Source Type: news
Inexpensive Steroids Can Save Lives Of Seriously Ill COVID-19 Patients
Multiple studies now confirm earlier research: Dexamethasone and hydrocortisone, drugs that reduce an immune system's overreaction, can help reduce deaths of hospitalized COVID-19 patients.(Image credit: Photo Illustration by Soumyabrata Roy/NurPhoto via Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - September 2, 2020 Category: Consumer Health News Authors: Richard Harris Source Type: news
Coronavirus treatment breakthrough: Cheap hydrocortisone steroid drastically cuts deaths
CORONAVIRUS update: The fight against coronavirus has been strengthened after studies have found hydrocortisone, an anti-inflammatory drug, drastically reduced mortality rate in the sickest patients. In light of the findings, the NHS plans to roll out the drug immediately. (Source: Daily Express - Health)
Source: Daily Express - Health - September 2, 2020 Category: Consumer Health News Source Type: news
WHO recommends cheap everyday steroids as Covid-19 treatment
Dexamethasone and hydrocortisone offer hope in curbing death toll (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - September 2, 2020 Category: Pharmaceuticals Source Type: news
Steroid found to improve survival of critically ill COVID-19 patients
A new international study published today has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery.
The study, led in the UK by Professor Anthony Gordon from Imperial College London with collaborators from the Intensive Care National Audit & Research Centre, found that patients receiving intensive care who were treated with a regular fixed dose of the steroid hydrocortisone for seven days had a better chance of recovery, compared with the patients who were not treated with the steroid. (Source: World Pharma News)
Source: World Pharma News - September 2, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
Effect of hydrocortisone on death, respiratory support among critically ill COVID-19 patients
(JAMA Network) The purpose of this randomized clinical trial in France was to evaluate the effect of low-dose hydrocortisone for the treatment of ICU patients with COVID-19-related acute respiratory failure but the trial was stopped early. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news
Steroid found to improve survival of critically ill COVID-19 patients
(Imperial College London) A new international study published today [02 September] has shown that treating critically ill patients with COVID-19 with the steroid hydrocortisone improves their chances of recovery. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news
Effect of hydrocortisone on death, organ support in patients with severe COVID-19
(JAMA Network) This randomized clinical trial of patients with severe COVID-19 was stopped early after results from another trial were released but this study investigated whether intravenous hydrocortisone (administered either as a seven-day fixed-dose course or restricted to when shock is clinically evident) improved 21-day organ support-free days. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news
Colocort (Hydrocortisone Rectal Suspension) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 23, 2020 Category: Drugs & Pharmacology Source Type: news
Treating sepsis with vitamin C, thiamine, and hydrocortisone: Exploring the quest for the magic elixir
The administration of ascorbic acid (vitamin C) alone or in combination with thiamine (vitamin B1) and corticosteroids (VCTS) has recently been hypothesized to improve hemodynamics, end-organ function, and may even increase survival in critically ill patients. This review aims to explore the current evidence and potential benefits and adverse effects of the VCTS regimen for the treatment of sepsis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 26, 2020 Category: Consumer Health News Source Type: news
Effects of hydrocortisone and yohimbine on decision-making under risk - Metz S, Waiblinger-Grigull T, Schulreich S, Chae WR, Otte C, Heekeren HR, Wingenfeld K.
INTRODUCTION: Many studies have investigated the influence of stress on decision-making. However, results are equivocal and the exact role of increased noradrenaline and cortisol after stress remains unclear. Using pharmacological manipulation, we investig... (Source: SafetyLit)
Source: SafetyLit - February 11, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial
RCT (n=216) found that treatment with intravenous vitamin C, hydrocortisone, and thiamine, compared with intravenous hydrocortisone alone, did not significantly improve the duration of time alive and free of vasopressor administration over 7 days. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 6, 2020 Category: Consumer Health News Source Type: news
High-Dose IV Vitamin C Does Not Speed Resolution of Septic Shock
FRIDAY, Jan. 24, 2020 -- Treatment with intravenous vitamin C, hydrocortisone, and thiamine does not improve the duration of time alive and vasopressor administration-free compared with intravenous hydrocortisone alone among patients with septic... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 24, 2020 Category: Pharmaceuticals Source Type: news
Vitamin Cocktail for Sepsis Fails; PPI for Stress Ulcer Prevention May Be Risky: ICU Studies Vitamin Cocktail for Sepsis Fails; PPI for Stress Ulcer Prevention May Be Risky: ICU Studies
A major new study of intensive care unit (ICU) patients with septic shock failed to find a benefit of giving an intravenous cocktail of vitamin C, hydrocortisone and thiamine, relative to hydrocortisone alone.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - January 22, 2020 Category: Intensive Care Tags: Critical Care News Source Type: news
Vitamin C-B1-steroid combo linked to lower septic shock mortality in kids
(Ann& Robert H. Lurie Children's Hospital of Chicago) Treating septic shock in children with a combination of intravenous vitamin C, vitamin B1 and hydrocortisone (a commonly used steroid) is associated with lower mortality, according to a study from Ann& Robert H. Lurie Children's Hospital of Chicago. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2020 Category: International Medicine & Public Health Source Type: news
