U.S. tightens access to some narcotic painkillers
New regulations will make Vicodin and other painkillers containing hydrocodone harder to get (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - August 22, 2014 Category: Consumer Health News Source Type: news

New Rules For Hydrocodone: What You Should Know
The #1 most prescribed drug, hydrocodone/acetaminophen combinations, are about to become more difficult for some to get. In an attempt to minimize abuse, will the change also affects patients with legitimate medical needs for the narcotic painkiller? (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - August 22, 2014 Category: Pharmaceuticals Authors: David Kroll Source Type: news

DEA tightens rules on hydrocodone products
One person dies every 19 minutes from a prescription drug overdose in the United States. On Thursday, the Drug Enforcement Administration tried to combat this epidemic by saying it will tighten controls on hydrocodone products, some of the most commonly misused narcotic painkillers on the market. (Source: WDSU.com - Health)
Source: WDSU.com - Health - August 22, 2014 Category: Consumer Health News Source Type: news

DEA tightens rules on hydrocodone products
Hydrocodone combination pills, also known as opiods, have moved from a Schedule III drug to a Schedule II drug. (Source: CNN.com - Health)
Source: CNN.com - Health - August 22, 2014 Category: Consumer Health News Source Type: news

Morning Break: Ice Bucket Challenger Dies, Vicodin Now Schedule II
(MedPage Today) -- Health news and commentary from around the Web, gathered by the MedPage Today staff. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - August 22, 2014 Category: Psychiatry Source Type: news

DEA tightens controls on hydrocodone painkiller drugs
The U.S. Drug Enforcement Administration is putting tighter controls on the nation's most widely prescribed narcotic painkiller in a move to stem an epidemic of addiction, overdose and death. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - August 22, 2014 Category: Science Source Type: news

DEA Further Restricts Hydrocodone Combination ProductsDEA Further Restricts Hydrocodone Combination Products
The US Drug Enforcement Administration has voted to move forward with rescheduling hydrocodone combination products from schedule III to schedule II drugs, an act that will take effect in 45 days. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - August 22, 2014 Category: Psychiatry Tags: Psychiatry News Source Type: news

Hydrocodone Products to Get More Severe, Schedule II Classification (FREE)
By Amy Orciari Herman Edited by André Sofair, MD, MPH Combination hydrocodone products, currently considered Schedule III drugs, will be reclassified as Schedule II because of their high risk for … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 22, 2014 Category: Primary Care Source Type: news

U.S. to tighten restrictions on common opioid painkillers
WASHINGTON (Reuters) - The U.S. government is tightening restrictions on hydrocodone, an opioid painkiller contained in Vicodin and other addictive drugs. (Source: Reuters: Health)
Source: Reuters: Health - August 22, 2014 Category: Consumer Health News Tags: healthNews Source Type: news

U.S. to Tighten Access to Certain Narcotic Painkillers
Drugs containing hydrocodone, which include Vicodin, would be affected (Source: WebMD Health)
Source: WebMD Health - August 22, 2014 Category: Consumer Health News Source Type: news

D.E.A. Increases Restrictions on Prescription Painkillers Like Vicodin
To tackle prescription drug abuse, new rules for dispensing hydrocodone, the most widely prescribed painkiller in the United States, include no phoned-in prescriptions and no refills. (Source: NYT Health)
Source: NYT Health - August 21, 2014 Category: Consumer Health News Authors: By SABRINA TAVERNISE Tags: Drug Enforcement Administration Pain-Relieving Drugs Katz, Nathaniel Drug Abuse and Traffic Source Type: news

In Move to Curb Drug Abuse, D.E.A. Tightens Rule on Widely Prescribed Painkiller
New rules for dispensing hydrocodone, the most widely prescribed painkiller in the United States, include no phoned-in prescriptions and no refills. (Source: NYT Health)
Source: NYT Health - August 21, 2014 Category: Consumer Health News Authors: By SABRINA TAVERNISE Tags: Drug Enforcement Administration Pain-Relieving Drugs Katz, Nathaniel Drug Abuse and Traffic Source Type: news

Update on Tamper-Proof Hydrocodone ProductsUpdate on Tamper-Proof Hydrocodone Products
Purdue and Zogenix report their progress in gaining approval for formulations of single-entity hydrocodone bitartrate that are difficult to misuse or abuse. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 9, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Purdue’s hydrocodone bitartrate tablets granted priority review designation
Purdue Pharma has been granted priority review designation by the US Food and Drug Administration (FDA) for its hydrocodone bitartrate extended-release tablets for treatment of chronic pain. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - July 9, 2014 Category: Pharmaceuticals Source Type: news

Must-read: the approval of Zohydro, and more tox on the web
Must-read of the week: Stephen S. Hall’s article “How Much Does It Hurt?” in the current edition of  New York magazine gives the best explanation I’ve seen of how the Food and Drug Administration ended up approving the extended-release hydrocodone product ZohydroER, even though their scientific advisory committee recommended against approval by a vote of 11-2. According to the article, Dr. Robert Rappaport, Director of the FDA’s Anesthesia, analgesia, and Addiction Products section, “reminded that advisory committee that it had to consider the Zohydro application within the nar...
Source: The Poison Review - June 16, 2014 Category: Toxicology Authors: Leon Tags: Medical ayahuasca FDA new york magazine zohydro Source Type: news

Drug users switch to heroin because it's cheap, easy to get
Drug users are attracted to heroin not only for the “high,” but because it is less expensive and easier to get than prescription painkillers, a nationwide survey of heroin users indicate. Researchers have found that many suburban drug users have made the switch. "In the past, heroin was a drug that introduced people to narcotics," said the principal investigator. "But what we're seeing now is that most people using heroin begin with prescription painkillers such as OxyContin, Percocet or Vicodin, and only switch to heroin when their prescription drug habits get too expensive." (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 28, 2014 Category: Science Source Type: news

Report: More than 300K seniors addicted to prescription drugs
Drugs include narcotic painkillers such as Percocet, Vicodin and anti-anxiety medicines like Xanax, Valium (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - May 21, 2014 Category: Consumer Health News Source Type: news

Methanol poisoning disaster in Kenya, and other tox on the web
Walking Dead Man: KDFW-TV in Dallas-fort Worth  is reporting that the synthetic cannabinoid responsible for sending at least 140 people to hospital in D-FW and Austin was packaged with the labels “Dead Man Walking” and “Walking Dead Man.” Signs and symptoms included psychosis, aggressive behavior, blackouts, and hyperthermia. You can read TPR‘s coverage of this outbreak here. 25I-NBOMe in Virginia: The CBS affiliate WUSA-TV in Washington D.C. recently reported that they were seeing more cases of intoxication from the psychedelic phenethylamine 25I-NBOMe. In one weekend last mont...
Source: The Poison Review - May 14, 2014 Category: Toxicology Authors: Leon Tags: Medical 25I-NBOMe canthardin groopman kenya liquid nitrogen poisoning methanol narcotic new leaf opiate opioids sapwell spanish fly synthetic cannabinoid toxic cocktail walking dead man Source Type: news

Novel Hydrocodone: 24-Hour Analgesia, Less Abuse PotentialNovel Hydrocodone: 24-Hour Analgesia, Less Abuse Potential
Once-daily, extended-release hydrocodone bitartrate provides persistent pain relief in patients with chronic nonmalignant and nonneuropathic pain and also comes with abuse-deterrent properties. Medscape Medical News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - May 2, 2014 Category: Emergency Medicine Tags: Neurology & Neurosurgery News Source Type: news

hydrocodone/homatropine (Tussigon; Hycodan)
Title: hydrocodone/homatropine (Tussigon; Hycodan)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 4/17/2014 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - April 17, 2014 Category: Drugs & Pharmacology Source Type: news

hydrocodone (Zohydro ER)
Title: hydrocodone (Zohydro ER)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 4/17/2014 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - April 17, 2014 Category: Drugs & Pharmacology Source Type: news

Safe Epidurals, Hydrocodone Rescheduling: The Pain Medicine News Report
(MedPage Today) -- A regular update on what's new in surgery from our friends at Pain Medicine News. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - April 17, 2014 Category: Psychiatry Source Type: news

US District Court Overturns Zohydro Ban in MassachusettsUS District Court Overturns Zohydro Ban in Massachusetts
Zogenix has won a preliminary injunction against the state ban on their single-entity hydrocodone after a judge found the ban is preempted by federal law. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 16, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Zogenix Files Suit Against State Ban on Zohydro ERZogenix Files Suit Against State Ban on Zohydro ER
After a decision by Massachusetts to ban the controversial single-entity hydrocodone, the company has filed for a restraining order, saying FDA regulatory authority 'simply should not be usurped by individual states.' Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 10, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

FDA approves 'rescue pen' aimed at curbing painkiller deaths
The auto-injector for caregivers or family members contains the drug naloxone, which can reverse the effects of OxyContin and Vicodin.Federal officials said Thursday they hoped a new "rescue pen" would help reduce the death toll from overdoses involving prescription painkillers. (Source: Los Angeles Times - Science)
Source: Los Angeles Times - Science - April 4, 2014 Category: Science Source Type: news

FDA Rebukes Efforts To Limit Access To FDA-Approved Zohydro
The FDA rebuked state and federal efforts to limit access to controversial non-abuse-deterrent pure hydrocone painkiller Zohydro ER (hydrocodone bitartrate). The drug is manufactured by pharmaceutical company Zogenix. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - April 3, 2014 Category: Pharmaceuticals Source Type: news

Massachusetts to Ban FDA-Approved Zohydro ERMassachusetts to Ban FDA-Approved Zohydro ER
The governor declares a public health emergency, announces actions to address opioid addiction epidemic, including banning the prescription and sale of the new controversial hydrocodone-only opioid. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 1, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Study: Powerful Painkillers Increasingly Prescribed In ERs
Emergency departments in America are increasingly prescribing strong painkilling drugs like Oxycontin and Vicodin amid rising use of the medications nationally. Prescriptions for narcotic painkillers, or opiates, in emergency departments rose 49 percent between 2001 and 2010, according to a study published in this month’s issue of Academic Emergency Medicine. Doctors have increasingly prescribed the potent painkillers in part because of a movement to improve pain management, according to CBS. But doctors are also increasingly incentivized to please patients—some hospitals offer pay incentives linked to patient ...
Source: TIME.com: Top Science and Health Stories - March 22, 2014 Category: Consumer Health News Authors: Noah Rayman Tags: Uncategorized medication Source Type: news

Study: Powerful Painkillers Increasingly Prescribed In ERs
Emergency departments in America are increasingly prescribing strong painkilling drugs like Oxycontin and Vicodin amid rising use of the medications nationally. Prescriptions for narcotic painkillers, or opiates, in emergency departments rose 49 perc... (Source: RWJF News Digest - Public Health)
Source: RWJF News Digest - Public Health - March 22, 2014 Category: American Health Authors: Robert Wood Johnson Foundation Source Type: news

Dramatic increase reported in opioid prescriptions during emergency department visits over the last decade
This report was published in the journal Academic Emergency Medicine."This trend is especially concerning given dramatic increases in opioid-related overdoses and fatalities in recent years," said Maryann Mazer-Amirshahi, M.D. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 17, 2014 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

FDA Commissioner Defends Zohydro Despite Abuse Potential (FREE)
By Joe Elia The FDA commissioner is defending the agency's decision to keep Zohydro ER — an extended-release formulation of hydrocodone — on the market despite warnings … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - March 17, 2014 Category: Primary Care Source Type: news

Significant increase in painkillers prescribed to US adults visiting emergency departments
Researchers report dramatic increases in prescriptions of opioid analgesics, such as Percocet, Vicodin, oxycodone and Dilaudid, during U.S. emergency department visits from 2001 to 2010. These findings were not explained by higher visit rates for painful conditions, which only increased modestly during the time period. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 14, 2014 Category: Science Source Type: news

Significant increase in painkillers prescribed to U.S. adults visiting emergency departments
Researchers report dramatic increases in prescriptions of opioid analgesics, such as Percocet, Vicodin, oxycodone and Dilaudid, during U.S. emergency department visits from 2001 to 2010. These findings were not explained by higher visit rates for painful conditions, which only increased modestly during the time period. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 14, 2014 Category: Science Source Type: news

Abuse-Deterrent Hydrocodone Passes Phase 3Abuse-Deterrent Hydrocodone Passes Phase 3
Topline study results show that a new extended-release, single-entity, abuse-deterrent hydrocodone formulation significantly reduces back pain compared with placebo. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Vicodin Not Superior to Tylenol #3 for Acute PainVicodin Not Superior to Tylenol #3 for Acute Pain
For acute pain, the 2 formulations show similar efficacy in a new study, which could be particularly important as Vicodin faces tighter restrictions. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 13, 2014 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

CVS Could Be Fined Millions in Case of Missing Painkillers
CVS Caremark could be fined for allegedly losing track of hydrocodone pills at four California stores (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - March 11, 2014 Category: Pharmaceuticals Source Type: news

Sriracha, Zohydro, and more: tox on the web
  http://www.youtube.com/watch?v=U2DJN0gnuI8 The science of Sriracha: The American Chemical Society has a must-see video on Sriracha hot sauce — it goes well with everything — including disquisitions about the origin of the Scoville scale and the physiology of capsaicinoids. (HT @ToxTalk) Early ads for sedatives: The Milwaukee Journal-Sentinel — which is doing some of the best reporting in the country on drugs and the pharmaceutical industry — has a great collection of medical journal ads for tranquilizers from the 1950s and 60s.  This post accompanies their story...
Source: The Poison Review - March 5, 2014 Category: Toxicology Authors: Leon Tags: Medical amphetamine drug screen capsaicin did she kill him Florence Maybrick gravel Kate Coloquhoun PVP pyrrolidinopentiophenone scoville scale sedative sriracha tox on the web tranquilizer advertisement zohydro Source Type: news

DEA Publishes Proposal to Reschedule Hydrocodone ProductsDEA Publishes Proposal to Reschedule Hydrocodone Products
Following advice from FDA and HHS, DEA published a formal proposal to reclassify hydrocodone combo products as Schedule II controlled substances. Meanwhile, public pushback of Zohydro approval grows. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - March 3, 2014 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Schumer to HHS: Ditch Zohydro
(MedPage Today) -- During a Monday press briefing, Sen. Charles Schumer (D-N.Y.) called on Health and Human Services Secretary Kathleen Sebelius to overturn the FDA's approval of Zohydro, a potent hydrocodone-only opioid approved last October. (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 3, 2014 Category: Neurology Source Type: news

Is Zohydro, The Super Potent New Opiate Painkiller, Just Too Dangerous?
A painkiller with up to 10 times the power of Vicodin shouldn't be allowed on the market, experts say (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 28, 2014 Category: Pharmaceuticals Authors: Melanie Haiken Source Type: news

Is The Super Potent New Opiate Painkiller Zohydro Just Too Dangerous?
A painkiller with up to 10 times the power of Vicodin shouldn't be allowed on the market, experts say (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 28, 2014 Category: Pharmaceuticals Authors: Melanie Haiken Source Type: news

Groups Ask FDA to Keep Zohydro ER Hydrocodone Off the Market (FREE)
By Kelly Young A coalition of consumer safety organizations, addiction treatment providers, and healthcare groups has asked the FDA to reconsider its approval of the high-dose hydrocodone capsule Zohydro ER because of its abuse potential. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - February 27, 2014 Category: Primary Care Source Type: news

Prescription Drug Misuse and Abuse During Pregnancy
Every decade or so, there is a “new” epidemic declared. This time, the media are publishing numerous articles about newborns whose mothers have used prescription medications, specifically narcotics, during pregnancy. read more (Source: Psychology Today Addiction Center)
Source: Psychology Today Addiction Center - January 21, 2014 Category: Addiction Authors: Ira J. Chasnoff, M.D. Tags: Addiction Media american medical association health team intravenous injection irritability journal of the american medical association lortab maternal and child health methadone misuse of prescription drugs morphine narcotic abuse Source Type: news

The 4th Annual Alexander Awards: Best Tox Reading of 2013
Alexander Gettler The coveted Alexander award is named in honor of Alexander Gettler (1883-1968), the chief toxicologist with the Office of the Medical Examiner of the City of New York during the first half of the 20th century. Gettler was a key figure in the development of modern forensic toxicology. By the way, Gettler will certainly be a key figure when a documentary based on Deborah Blum’s book The Poisoner’s Handbook: Murder and the Birth of Forensic Medicine in Jazz Age New York is broadcast in early January on the PBS series “American Experience.” To be eligible to win an Alexander, an a...
Source: The Poison Review - December 31, 2013 Category: Toxicology Authors: Leon Tags: Medical long form journalism medical toxicology Source Type: news

28 State AGs Ask FDA to Reconsider Approval of Zohydro ER Because of Abuse Potential (FREE)
By Kelly Young Twenty-eight state attorneys general have asked the FDA to reconsider its approval of Zohydro ER, a hydrocodone-only painkiller, or consider an expedited schedule for developing an abuse-deterrent version. In … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - December 16, 2013 Category: Primary Care Source Type: news

Mallinckrodt reports positive efficacy results from Phase III study of pain drug
Mallinckrodt has released positive efficacy results from the Phase III clinical trial of MNK-155, an investigational extended-release oral formulation of hydrocodone and acetaminophen evaluated for the management of moderate to moderately severe acut… (Source: Drug Development Technology)
Source: Drug Development Technology - December 13, 2013 Category: Pharmaceuticals Source Type: news

Killing Pain: AGs Want FDA to Review Zohydro Approval
(MedPage Today) -- Attorneys general from 28 states have asked the U.S. Food and Drug Administration to reconsider its approval of the powerful narcotic painkiller known as Zohydro (hydrocodone bitartrate). (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 12, 2013 Category: Psychiatry Source Type: news

hydrocodone/acetaminophen, Vicodin, Vicodin ES, Vicodin HP, Anexsia, Lortab, Lorcet, Lorcet Plus, No
Title: hydrocodone/acetaminophen, Vicodin, Vicodin ES, Vicodin HP, Anexsia, Lortab, Lorcet, Lorcet Plus, NoCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 12/11/2013 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - December 11, 2013 Category: Anesthesiology Source Type: news

hydrocodone/acetaminophen, Vicodin, Vicodin ES, Vicodin HP, Anexsia, Lortab, Lorcet, Lorcet Plus, No
Title: hydrocodone/acetaminophen, Vicodin, Vicodin ES, Vicodin HP, Anexsia, Lortab, Lorcet, Lorcet Plus, NoCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 12/11/2013 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - December 11, 2013 Category: Drugs & Pharmacology Source Type: news

FDA recommends schedule II for hydrocodone combinations
Read the full story on MD Consult: FDA recommends schedule II for hydrocodone combinations (Source: MD Consult: News: Top Stories)
Source: MD Consult: News: Top Stories - December 10, 2013 Category: Journals (General) Source Type: news