Les meilleures études en 2023 adaptées aux soins primaires: De l’équipe du groupe PEER
CONCLUSION: La recherche publiée en 2023 a produit plusieurs articles de grande qualité sur divers sujets d’intérêt en soins primaires, dont les soins cardiovasculaires, le syndrome du côlon irritable, les soins aux aînés et la prise en charge de l’acné.PMID:38626994 | DOI:10.46747/cfp.7004e47 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research
Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research
Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Pain Physician)
Source: Pain Physician - April 16, 2024 Category: Anesthesiology Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research
Top studies of 2023 relevant to primary care: From the PEER team
CONCLUSION: Research published in 2023 yielded several high-quality articles with topics relevant to primary care, including cardiovascular care, irritable bowel syndrome, care of the elderly, and acne management.PMID:38626998 | DOI:10.46747/cfp.7004245 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research
Les meilleures études en 2023 adaptées aux soins primaires: De l’équipe du groupe PEER
CONCLUSION: La recherche publiée en 2023 a produit plusieurs articles de grande qualité sur divers sujets d’intérêt en soins primaires, dont les soins cardiovasculaires, le syndrome du côlon irritable, les soins aux aînés et la prise en charge de l’acné.PMID:38626994 | DOI:10.46747/cfp.7004e47 (Source: Canadian Family Physician Medecin de Famille Canadien)
Source: Canadian Family Physician Medecin de Famille Canadien - April 16, 2024 Category: Primary Care Authors: Betsy S Thomas Danielle Perry Samantha S Moe Ricky D Turgeon Jen Potter Émélie Braschi Nicholas Dugr é Jessica E M Kirkwood G Michael Allan Source Type: research
Nephrology: What You May Have Missed in 2023
This article highlights a selection of important nephrology studies published in 2023 that have relevance for nonnephrologist physicians. Four studies examined progression of chronic kidney disease or cardiovascular disease with respect to finerenone use, magnesium supplementation, iron markers, and COVID-19. Two studies examined treatments to improve specific aspects of chronic kidney disease management, including daprodustat to address anemia and patiromer to address hyperphosphatemia. One study showed that acetazolamide added to loop diuretics increased diuresis in acute decompensated heart failure across a wide range o...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Ali A M AlHabobi Ashwaq M S Almutairi Danah A S Y Bohemid Ashwini R Sehgal Source Type: research
Nephrology: What You May Have Missed in 2023
This article highlights a selection of important nephrology studies published in 2023 that have relevance for nonnephrologist physicians. Four studies examined progression of chronic kidney disease or cardiovascular disease with respect to finerenone use, magnesium supplementation, iron markers, and COVID-19. Two studies examined treatments to improve specific aspects of chronic kidney disease management, including daprodustat to address anemia and patiromer to address hyperphosphatemia. One study showed that acetazolamide added to loop diuretics increased diuresis in acute decompensated heart failure across a wide range o...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Ali A M AlHabobi Ashwaq M S Almutairi Danah A S Y Bohemid Ashwini R Sehgal Source Type: research
Nephrology: What You May Have Missed in 2023
This article highlights a selection of important nephrology studies published in 2023 that have relevance for nonnephrologist physicians. Four studies examined progression of chronic kidney disease or cardiovascular disease with respect to finerenone use, magnesium supplementation, iron markers, and COVID-19. Two studies examined treatments to improve specific aspects of chronic kidney disease management, including daprodustat to address anemia and patiromer to address hyperphosphatemia. One study showed that acetazolamide added to loop diuretics increased diuresis in acute decompensated heart failure across a wide range o...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Ali A M AlHabobi Ashwaq M S Almutairi Danah A S Y Bohemid Ashwini R Sehgal Source Type: research
Nephrology: What You May Have Missed in 2023
This article highlights a selection of important nephrology studies published in 2023 that have relevance for nonnephrologist physicians. Four studies examined progression of chronic kidney disease or cardiovascular disease with respect to finerenone use, magnesium supplementation, iron markers, and COVID-19. Two studies examined treatments to improve specific aspects of chronic kidney disease management, including daprodustat to address anemia and patiromer to address hyperphosphatemia. One study showed that acetazolamide added to loop diuretics increased diuresis in acute decompensated heart failure across a wide range o...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Ali A M AlHabobi Ashwaq M S Almutairi Danah A S Y Bohemid Ashwini R Sehgal Source Type: research
A Refined Thin-Film Model for Drug Dissolution Considering Radial Diffusion – Simulating Powder Dissolution
ConclusionThe study demonstrated the potential of the radial diffusion-based model to describe dissolution of drug powders. In contrast, the classic Nernst-Brunner equation could under-estimate drug dissolution rate, largely due to the underlying assumption of translational diffusion. Moreover, the study indicated that not all surfaces on a drug particle contribute to dissolution. Therefore, relying on the experimentally-determined specific surface area for predicting drug dissolution is not advisable. (Source: Pharmaceutical Research)
Source: Pharmaceutical Research - April 8, 2024 Category: Drugs & Pharmacology Source Type: research
Sacubitril/valsartan reversal of left ventricular remodeling is associated with improved hemodynamics in resistant hypertension
CONCLUSIONS: Switching from olmesartan to S/V effectively lowered BP and reversed ventricular remodeling in RHTN. In addition, hemodynamics improvement was also observed. Changes in hemodynamics played an important role in reversing LV remodeling of S/V, which were independent of its antihypertensive effect.PMID:38582140 | DOI:10.1016/j.hjc.2024.03.012 (Source: Hellenic Journal of Cardiology)
Source: Hellenic Journal of Cardiology - April 6, 2024 Category: Cardiology Authors: Lixue Song Hongrui Yang Xiang Ning Yanyan Ma Aiying Xue Yimeng Du Qinghua Lu Zhendong Liu Xin Wang Juan Wang Source Type: research
Renal upregulation of NCC counteracts empagliflozin-mediated NHE3 inhibition in normotensive but not in hypertensive male rats
This study examined the effect of empagliflozin (EMPA) on renal tubular sodium transport in normotensive and spontaneously hypertensive rats (SHRs). It also tested the hypothesis that EMPA-mediated PT NHE3 inhibition in normotensive rats is associated with upregulation of distal nephron apical sodium transporters. EMPA administration for 14 days reduced BP in 12-week-old SHRs but not in age-matched Wistar rats. PT NHE3 activity was inhibited by EMPA treatment in both Wistar and SHRs. In Wistar rats, EMPA increased NCC activity, mRNA expression, protein abundance, and phosphorylation levels, but not in SHRs. SHRs showed hig...
Source: American Journal of Physiology. Cell Physiology - April 1, 2024 Category: Cytology Authors: Paulo C Castro Thiago Matheus Santos-Rios Fl ávia Letícia Martins Renato O Crajoinas Marcos Vin ícius Caetano Luc ília M A Lessa Weverton Machado Luchi James A McCormick Adriana C C Girardi Source Type: research
Renal upregulation of NCC counteracts empagliflozin-mediated NHE3 inhibition in normotensive but not in hypertensive male rats
This study examined the effect of empagliflozin (EMPA) on renal tubular sodium transport in normotensive and spontaneously hypertensive rats (SHRs). It also tested the hypothesis that EMPA-mediated PT NHE3 inhibition in normotensive rats is associated with upregulation of distal nephron apical sodium transporters. EMPA administration for 14 days reduced BP in 12-week-old SHRs but not in age-matched Wistar rats. PT NHE3 activity was inhibited by EMPA treatment in both Wistar and SHRs. In Wistar rats, EMPA increased NCC activity, mRNA expression, protein abundance, and phosphorylation levels, but not in SHRs. SHRs showed hig...
Source: Am J Physiol Cell Ph... - April 1, 2024 Category: Cytology Authors: Paulo C Castro Thiago Matheus Santos-Rios Fl ávia Letícia Martins Renato O Crajoinas Marcos Vin ícius Caetano Luc ília M A Lessa Weverton Machado Luchi James A McCormick Adriana C C Girardi Source Type: research
Renal upregulation of NCC counteracts empagliflozin-mediated NHE3 inhibition in normotensive but not in hypertensive male rats
This study examined the effect of empagliflozin (EMPA) on renal tubular sodium transport in normotensive and spontaneously hypertensive rats (SHRs). It also tested the hypothesis that EMPA-mediated PT NHE3 inhibition in normotensive rats is associated with upregulation of distal nephron apical sodium transporters. EMPA administration for 14 days reduced BP in 12-week-old SHRs but not in age-matched Wistar rats. PT NHE3 activity was inhibited by EMPA treatment in both Wistar and SHRs. In Wistar rats, EMPA increased NCC activity, mRNA expression, protein abundance, and phosphorylation levels, but not in SHRs. SHRs showed hig...
Source: Am J Physiol Cell Ph... - April 1, 2024 Category: Cytology Authors: Paulo C Castro Thiago Matheus Santos-Rios Fl ávia Letícia Martins Renato O Crajoinas Marcos Vin ícius Caetano Luc ília M A Lessa Weverton Machado Luchi James A McCormick Adriana C C Girardi Source Type: research
