Vasodilators For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In summary, vasodilators play a pivotal role in managing cardiovascular conditions, including hypertension, which is rapidly becoming a global health concern. By expanding the body’s blood vessels, these unique medications can improve blood flow and decrease the pressure exerted by the heart, thereby providing relief to numerous patients worldwide. Their applications are diverse, extending beyond hypertension to conditions like angina, heart failure, and even erectile dysfunction. However, these medications should be taken carefully and always under the supervision of a doctor due to the potent...
Source: The EMT Spot - July 27, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

A 31 year old with Diabetes and HTN complains of bilateral arm tingling and headache
This ECG was texted to me with the message " A 31 year old with Diabetes and HTN complains of bilateral arm tingling and headache. "There is high lateral ST Elevation and inferior reciprocal ST depression.There is also STE in V2.The computer calls it a STEMI.What do you think?STE in I, aVL and V2 is a pattern associated with "Mid-anterolateral OMI, " which is seen with OMI of the first Diagonal.  See more of Mid-anterolateral OMII wrote back: " I think this is a false positive due to LVH.  PseudoSTEMI.  I can ' t tell you exactly why.  It just looks like it.  ECGs are often like faces to me.&n...
Source: Dr. Smith's ECG Blog - August 29, 2020 Category: Cardiology Authors: Steve Smith Source Type: blogs

Investigations and management of dilated cardiomyopathy
Investigations in dilated cardiomyopathy Chest X-ray PA view will assess the cardiac size in dilated cardiomyopathy and show evidence of pulmonary congestion. Sick persons may present with features of frank pulmonary edema in the form of hilar haze or bat wing pattern of pulmonary edema. Significant left ventricular dysfunction can exist without much of cardiomegaly on chest X-ray as well. ECG may show sinus tachycardia, left atrial overload and sometimes left ventricular hypertrophy. A wide QRS complex with left bundle branch block pattern may indicate potential benefit from cardiac resynchronization therapy (CRT). ECG ...
Source: Cardiophile MD - March 30, 2019 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: General Cardiology Source Type: blogs

A Class of Calorie Restriction Mimetic Targeting NRF2
NRF2, or SKN-1 in the nematode worm Caenorhabditis elegans, is one of the many coordinating stress response genes activated by calorie restriction or a range of other forms of mild cellular stress. Part of the way in which this results in improved health and extended life span in a range of species is through activating cellular protection and repair mechanisms. Researchers are interested in ways to recapture this reaction to stress via pharmaceuticals rather than diet, and so are working their way through the drug databases in search of prospects. The results here are an example of the sort of thing they are looking for: ...
Source: Fight Aging! - December 21, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Making Research Suppressed Again - US Secretary of Health Candidate Accused of Suppressing Clinical Research at Behest of Campaign Donor
This report is greater than 5 years old. Findings may be used for research purposes but should not be considered current. 'In particular,Gary Beck, a policy assistant to the congressman, first reached out to the federal research agency about the study in July, emails show. ' I have been in contact with representatives from Arbor Pharmaceuticals based in Georgia in regard to some issues they have with the study that is linked below, ' he wrote, adding that the company told him ' the study might be outdated ' and they wanted it removed from the website.' I wanted to get in touch with you to get a better grasp on the situatio...
Source: Health Care Renewal - January 20, 2017 Category: Health Management Tags: BilDil CHF conflicts of interest evidence-based medicine health care corruption Nitromed suppression of medical research Source Type: blogs

Dyspnea and Convex ST elevation, Marked LVH, with Bedside Echos
Case 1.Chief complaint: A 60-something African American male with 5 days of increasing SOB with dyspnea on exertion.This male in his 60's has a PMH of CAD with MI and CABG, HTN with LVH, hyperlipidemia, and mild HF with only moderately reduced ejection fraction (and some diastolic dysfunction as well).He presents with 5 days of worsening shortness of breath with orthopnea as well as chest pain.  His BP is 191/90.  He also has a history of venous thromboembolism and has not been taking his anticoagulants.  He was also off of his BP meds (lisinopril, amlodipine and carvedilol).Here is his ED ECG (ECG #1):...
Source: Dr. Smith's ECG Blog - July 13, 2016 Category: Cardiology Authors: Steve Smith Source Type: blogs

Inferior ST Elevation. BP 250/140.
This 50-something patient with no previous CAD complained of havinng had chest pressure the day prior, but stated she was asymptomatic at the time of the ECG.  Her blood pressure was 250/140.  She was well appearing.  She admitted to long standing untreated hypertension.Sinus rhythm.  Very high voltage in the precordium, meeting criteria for LVH, though without the repolarization abnormalities typically associated. There is ST elevation in inferior leads that is diagnostic of focal injury.  The T-wave is inverted in these leads; this is a strong sign of recent reperfusion of the infarct-related art...
Source: Dr. Smith's ECG Blog - September 2, 2014 Category: Cardiology Authors: Steve Smith Source Type: blogs

Medical Mispronunciations and Misspelled Words: The Definitive List.
Hearing medical mispronunciations and seeing misspelled words are an under appreciated  joy of working in healthcare.  Physicians often forget just how alien the language of medicine is to people who don't live it everyday.  The best part about being a physician is not helping people recover from critical illness. The best part is not  about  listening and understanding with compassion and empathy.  Nope, the best part about being a physician is hearing patients and other healthcare providers butcher the language of medicine and experiencing great entertainment in the process.   Doctors c...
Source: The Happy Hospitalist - October 2, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs