Impeding white blood cells in antiphospholipid syndrome reduced blood clots
(Michigan Medicine - University of Michigan) A new study examined APS at the cellular level and found that two drugs reduced development of blood clots in mice affected with the condition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 25, 2019 Category: International Medicine & Public Health Source Type: news
Antiphospholipid Syndrome: Insights Into a Rare Autoimmune Disease Antiphospholipid Syndrome: Insights Into a Rare Autoimmune Disease
A conversation with Dr Doruk Erkan about the proper diagnosis and management of this life-threatening clotting disease.Hospital for Special Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 29, 2019 Category: Consumer Health News Tags: Rheumatology Expert Interview Source Type: news
Presence of Antiphospholipid Antibodies Tied to First-Time MI
FRIDAY, Nov. 30, 2018 -- There is a strong and independent association between the presence of antiphospholipid antibodies (aPLs) and first-time myocardial infarction (MI), according to a research letter published recently in the Annals of Internal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 30, 2018 Category: Pharmaceuticals Source Type: news
Pregnancy and APS: Results Look Encouraging (CME/CE)
(MedPage Today) -- Intrauterine fetal death was the first sign in most women with antiphospholipid syndrome (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 7, 2018 Category: Rheumatology Source Type: news
Antiphospholipid Antibody Linked to First MI Antiphospholipid Antibody Linked to First MI
The case-control PAROKRANK study identified a strong association between an anticardiolipin antibody and MI, but also raises a host of new questions about the relationship.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 23, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news
Antibodies Common in Autoimmune Disorders Could Be MI Risk Factor
(MedPage Today) -- Antiphospholipid antibodies out-predicted conventional factors (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - October 23, 2018 Category: Rheumatology Source Type: news
Antibodies linked to heart attacks
(Karolinska Institutet) Levels of antiphospholipid antibodies, which are associated with rheumatic diseases, are also elevated in myocardial infarction without any autoimmune co-morbidity, a study from Karolinska Institutet in Sweden published in The Annals of Internal Medicine reports. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 22, 2018 Category: International Medicine & Public Health Source Type: news
Across the Table on Antiphospholipid Syndrome
(MedPage Today) -- Jack Cush, MD, and Doruk Erkan, MD, MPH, discuss this sometimes frustrating condition (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - December 31, 2017 Category: American Health Source Type: news
Networks of enzymatically oxidized membrane lipids support calcium-dependent coagulation factor binding to maintain hemostasis
Blood coagulation functions as part of the innate immune system by preventing bacterial invasion, and it is critical to stopping blood loss (hemostasis). Coagulation involves the external membrane surface of activated platelets and leukocytes. Using lipidomic, genetic, biochemical, and mathematical modeling approaches, we found that enzymatically oxidized phospholipids (eoxPLs) generated by the activity of leukocyte or platelet lipoxygenases (LOXs) were required for normal hemostasis and promoted coagulation factor activities in a Ca2+- and phosphatidylserine (PS)–dependent manner. In wild-type mice, hydroxyeicosatet...
Source: Signal Transduction Knowledge Environment - November 28, 2017 Category: Science Authors: Lauder, S. N., Allen-Redpath, K., Slatter, D. A., Aldrovandi, M., OConnor, A., Farewell, D., Percy, C. L., Molhoek, J. E., Rannikko, S., Tyrrell, V. J., Ferla, S., Milne, G. L., Poole, A. W., Thomas, C. P., Obaji, S., Taylor, P. R., Jones, S. A., de Groot Tags: STKE Research Articles Source Type: news
Heartbroken woman, 23, who lost five babies in six years
Shannon Reed, 23, from Prudhoe, near Newcastle, has been diagnosed with 'sticky blood syndrome', or antiphospholipid syndrome - after years of mystery surrounding her miscarriages. (Source: the Mail online | Health)
Source: the Mail online | Health - November 8, 2017 Category: Consumer Health News Source Type: news
Antiphospholipid syndrome: diagnosis and management
Dr Anisur Rahman and Dr Salma Ahmed discuss the diagnosis and management of antiphospholipid syndrome (APS). (Source: GP Online Education)
Source: GP Online Education - September 13, 2017 Category: Primary Care Tags: Autoimmune disorders Source Type: news
Heparin, ASA Aids Live Birth With Antiphospholipid Antibody Heparin, ASA Aids Live Birth With Antiphospholipid Antibody
Unfractionated heparin added to aspirin is superior to aspirin alone in promoting live births among women with antiphospholipid syndrome and recurrent pregnancy loss, a meta-analysis shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 20, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news
Prevalence of Antiphospholipid Syndrome Up for Roma SLE
Roma systemic lupus erythematosus patients also have significantly higher prevalence of abortions (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 14, 2017 Category: Cancer & Oncology Tags: Gynecology, Oncology, Pathology, Rheumatology, Journal, Source Type: news
Antiphospholipid Syndrome: Role of Vascular Endothelial Cells Antiphospholipid Syndrome: Role of Vascular Endothelial Cells
This review explores the role of vascular endothelial cell dysfunction in antiphospholipid syndrome, an autoimmune prothrombotic condition. Might this pathway provide a viable target for therapy?Journal of the American College of Cardiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 5, 2017 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Gut bacteria may be a trigger for antiphospholipid syndrome
The gut microbiomes of patients with antiphospholipid syndrome show higher levels of phospholipid-producing bacteria, and this findings point to microbes being a trigger for this life-threatening disease, according to new research. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - November 13, 2016 Category: Science Source Type: news
