OMI in a pediatric patient? Teenagers do get acute coronary occlusion, so don't automatically dismiss the idea.
 Acute coronary syndrome in a pediatric patient?Written by Kirsten Morrissey, MD with edits by Bracey, Grauer, Meyers, and Smith An older teen was transferred from an outside hospital with elevated serum troponin and and ECG demonstrating ST elevations.  The patient was obese and had a medical history of only recurrent tonsillitis status post tonsillectomy and adenoidectomy but was otherwise healthy and fully vaccinated. He reported 1.5 days of chest pain that started as substernal and crushing in nature awakening him from sleep and occasionally traveling to right side of neck.  The pain ...
Source: Dr. Smith's ECG Blog - December 5, 2023 Category: Cardiology Authors: Bracey Source Type: blogs

Thrombus, tumor or vegetation?
This question is often faced by the echocardiographer while evaluating a mass detected on the heart valves or cardiac chambers. Usual method is to take it in the clinical context. There could also be non-infective vegetations of marantic endocarditis which are almost impossible to differentiate from infective vegetations. Marantic vegetations can be suspected in the presence of small and multiple vegetations changing from one examination to another, without associated abscess or valve destruction [1]. It may be noted that echocardiography is neither 100% specific nor 100% sensitive for the diagnosis of infective endocardi...
Source: Cardiophile MD - December 15, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Why immune testing for patients with repeated IVF failures and repeated miscarriages is a waste of time and money
Patients who have failed repeated IVF cycles even though apparently perfect embryos were transferred, are understandably upset, frustrated and distressed. They are looking for answers as to why they are not getting pregnant, and a plausible reason is that their body is "rejecting" their embryos. This is why immune testing for patients with reproductive failure has become very fashionable recently. There is a long list of expensive tests which many labs now perform - and these include: DQ Alpha, Leukocyte Antibody Detection, Reproductive Immunophenotype, ANA (Antinuclear Antibody), Anti-DNA/Histone Antibodies, APA (Ant...
Source: Dr.Malpani's Blog - May 28, 2020 Category: Reproduction Medicine Source Type: blogs

What's new in midwifery - 13th May 2020
Some new things you might want to know...COVID-19Coronavirus disease 2019 (COVID-19) and pregnancy: a systematic review (Journal of Maternal-Fetal and Neonatal Medicine)ResearchAspirin or heparin or both for improving pregnancy outcomes in women with persistent antiphospholipid antibodies and recurrent pregnancy loss (Cochrane review)Association of Gestational Age at Birth With Risk of Perinatal Mortality and Special Educational Need Among Twins (JAMA Pediatrics)Any problems accessing full text?  If you have a librarian, ask them!Acknowledgements:McMaster Evidence Alerts (you can sign up with them to receive...
Source: Browsing - May 13, 2020 Category: Databases & Libraries Tags: midwifery Source Type: blogs

Rationale for Testing Anticoagulants Against COVID-19
This article originally appeared on the Timmerman Report here. The post Rationale for Testing Anticoagulants Against COVID-19 appeared first on The Health Care Blog. (Source: The Health Care Blog)
Source: The Health Care Blog - April 16, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Patients Physicians anticoagulants cardiology coronavirus Ethan Weiss thrombosis Source Type: blogs

Funtabulously Frivolous Friday Five 261
Just when you thought your brain could unwind on a Friday! Time to GUESS THE DISEASE challenge for Funtabulously Frivolous Friday Five 261 The post Funtabulously Frivolous Friday Five 261 appeared first on Life in the Fast Lane. (Source: Life in the Fast Lane)
Source: Life in the Fast Lane - November 30, 2018 Category: Emergency Medicine Authors: Neil Long Tags: FFFF antiphospholipid syndrome APS Benjamin Sacks Catastrophic APS Cyclophosphamide Emanuel Libman endocarditis Glucocorticoids IVIG Libman-Sacks endocarditis Livedo reticularis plasma exchange Salmonella shrinking lung syndrom Source Type: blogs

Antiphospholipid Syndrome
Antiphospholipid Syndrome (APS) important in vascular medicine as well as obstetrics. In obstetrics, it is important because it can cause fetal loss, intrauterine growth retardation and severe preeclampsia. In vascular medicine it is important because it can cause thrombotic events which could be arterial, venous or microvascular [1]. It can also be accompanied by moderate thrombocytopenia [2]. Thrombotic events involving multiple organs may be termed catastrophic Antiphospholipid Syndrome [3]. APS is an autoimmune disease with antibodies directed against beta2 glycoprotein I. This leads to suppression of tissue factor p...
Source: Cardiophile MD - May 27, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology anti beta2 glycoprotein I antibodies anti cardiolipin antibodies lupus anticoagulant Source Type: blogs

Can you use DOACs in patients with antiphospholipid syndrome?
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - September 4, 2017 Category: Internal Medicine Source Type: blogs

Wheat Belly: Self-Directed Health?
Director chair, film slate and load horn. Here’s a proposal for you: If, by following the Wheat Belly lifestyle, a long list of conditions are reduced or reversed at no risk, almost no cost, reversing even chronic and potentially fatal conditions . . . does that mean that the notion of self-directed health might be on the horizon, i.e., putting control over health back in our own hands? I think it does. No, we will never implant our own defibrillators or take out our own gallbladders. But so many chronic health conditions afflicting modern humans recede that I believe that it is entirely reasonable to start talking a...
Source: Wheat Belly Blog - February 16, 2016 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle arthritis autoimmune diabetes eating disorder gluten grains Inflammation joint Weight Loss Source Type: blogs

DM / DNB Cardiology Entrance Mock Test 11
Please wait while the activity loads. If this activity does not load, try refreshing your browser. Also, this page requires javascript. Please visit using a browser with javascript enabled. If loading fails, click here to try again Click on the 'Start' button to begin the mock test. After answering all questions, click on the 'Get Results' button to display your score and the explanations. There is no time limit for this mock test. Start Congratulations - you have completed DM / DNB Cardiology Entrance Mock Test 11.You scored %%SCORE%% out of %%TOTAL%%.Your performance has ...
Source: Cardiophile MD - February 3, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs

Failures of target specific oral anticoagulants (TSOACs) in patients with antiphospholipid syndrome
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - January 18, 2015 Category: Internists and Doctors of Medicine Tags: cardiovascular hematology Source Type: blogs

LITFL Review 156
Welcome to the 156th LITFL Review. Your regular and reliable source for the highest highlights, sneakiest sneak peeks and loudest shout-outs from the webbed world of emergency medicine and critical care. Each week the LITFL team casts the spotlight on the blogosphere’s best and brightest and deliver a bite-sized chuck of FOAM. The Most Fair Dinkum Ripper Beauts of the Week Is clot retrieval in ischemic stroke the next development? Caution in allowing one marginally positive study to change practice. Rory Spiegel implores us to study our past mistakes (NINDS-2) so as to avoid repeating them. [AS] Master your manageme...
Source: Life in the Fast Lane - November 17, 2014 Category: Emergency Medicine Authors: Marjorie Lazoff, MD Tags: Education LITFL review LITFL R/V Source Type: blogs

Cardiology MCQ 301: Flash pulmonary edema in renal artery stenosis
Flash pulmonary edema in renal artery stenosis is known as: a) Pickering Syndrome b) Pickwickian syndrome c) Hughes Syndrome d) None of the above ["Click here for the answer with explanation", "Correct Answer:"] a) Pickering Syndrome Pickwickian syndrome is characterised by obesity and hypoventilation. Hughes Syndrome is antiphospholipid syndrome or antiphospholipid antibody syndrome. Flash pulmonary edema in renal artery stenosis has been called Pickering Syndrome. Read more… The post Cardiology MCQ 301: Flash pulmonary edema in renal artery stenosis appeared first on Cardiophile MD. (Source: Cardiophile MD)
Source: Cardiophile MD - September 12, 2014 Category: Cardiology Authors: Prof. Dr. Johnson Francis MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Critical Care Compendium update
LITFL’s Critical Care Compendium is a comprehensive collection of pages concisely covering the core topics and controversies of critical care. Currently there are almost 1,500 entries with more in the works… Some pages are more developed than others, and all the pages are being constantly revised and improved. Links to new references and online resources are added daily, with an emphasis on those that are free and open access (FOAM!). These pages originated from the FCICM exam study notes created by Dr Jeremy Fernando in 2011, and have been updated, modified and added to since. As such will be particularly us...
Source: Life in the Fast Lane - November 17, 2013 Category: Emergency Medicine Doctors Authors: Chris Nickson Tags: Critical Care Compendium Education eLearning Emergency Medicine Featured CCC LITFL collection Source Type: blogs

Gliadin: The Universal Human Poison
Autoimmunity is the process describing an immune response waged against our own organs. The complex collection of mechanisms consisting of T and B lymphocytes, antibodies, and others, meant to provide protection against viruses, bacteria, and other body invaders, is misdirected against proteins of the body’s organs, such as liver, pancreas, thyroid, or brain. Autoimmune conditions now affect 8% of the American population–it is increasingly looking like diseases of autoimmunity are out of control. Dr Alessio Fasano was recently awarded the Linus Pauling Award, the highest award from the Institute for Functional...
Source: Wheat Belly Blog - October 7, 2013 Category: Cardiology Authors: Dr. Davis Tags: Autoimmunity Gliadin Source Type: blogs