Oncolytic virotherapy for metastatic breast cancer – a case report
ConclusionIntegration of IT-OV immunotherapy in standard treatment protocols presents an attractive modality for late-stage primary tumors with an abscopal effect on metastases. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - June 7, 2023 Category: Cancer & Oncology Source Type: research
Breaking down barriers for prescribing and using hormone therapy for the treatment of menopausal symptoms: an experts' perspective
Expert Rev Clin Pharmacol. 2023 Jun 5:1-11. doi: 10.1080/17512433.2023.2219056. Online ahead of print.ABSTRACTINTRODUCTION: Around 80% of women suffer menopause-related symptoms that affect their daily activities and quality of life. Menopausal hormone therapy (MHT) has proven to be beneficial in relieving these symptoms. Nevertheless, only 20/30% of symptomatic women seek treatment. This has resulted in neglect of a generation of healthcare professionals' (HCPs) education in menopausal medicine and a reduction in the prescription of MHT in menopausal women for over two decades.AREAS COVERED: The aim of this article was to...
Source: Clinical Breast Cancer - June 6, 2023 Category: Cancer & Oncology Authors: Serge Rozenberg Nick Panay Marco Gambacciani Antonio Cano Sarah Gray Katrin Schaudig Source Type: research
Breaking down barriers for prescribing and using hormone therapy for the treatment of menopausal symptoms: an experts' perspective
Expert Rev Clin Pharmacol. 2023 Jun 5:1-11. doi: 10.1080/17512433.2023.2219056. Online ahead of print.ABSTRACTINTRODUCTION: Around 80% of women suffer menopause-related symptoms that affect their daily activities and quality of life. Menopausal hormone therapy (MHT) has proven to be beneficial in relieving these symptoms. Nevertheless, only 20/30% of symptomatic women seek treatment. This has resulted in neglect of a generation of healthcare professionals' (HCPs) education in menopausal medicine and a reduction in the prescription of MHT in menopausal women for over two decades.AREAS COVERED: The aim of this article was to...
Source: Clinical Genitourinary Cancer - June 6, 2023 Category: Cancer & Oncology Authors: Serge Rozenberg Nick Panay Marco Gambacciani Antonio Cano Sarah Gray Katrin Schaudig Source Type: research
Breaking down barriers for prescribing and using hormone therapy for the treatment of menopausal symptoms: an experts' perspective
Expert Rev Clin Pharmacol. 2023 Jun 5:1-11. doi: 10.1080/17512433.2023.2219056. Online ahead of print.ABSTRACTINTRODUCTION: Around 80% of women suffer menopause-related symptoms that affect their daily activities and quality of life. Menopausal hormone therapy (MHT) has proven to be beneficial in relieving these symptoms. Nevertheless, only 20/30% of symptomatic women seek treatment. This has resulted in neglect of a generation of healthcare professionals' (HCPs) education in menopausal medicine and a reduction in the prescription of MHT in menopausal women for over two decades.AREAS COVERED: The aim of this article was to...
Source: Pharmacological Reviews - June 6, 2023 Category: Drugs & Pharmacology Authors: Serge Rozenberg Nick Panay Marco Gambacciani Antonio Cano Sarah Gray Katrin Schaudig Source Type: research
Breaking down barriers for prescribing and using hormone therapy for the treatment of menopausal symptoms: an experts' perspective
Expert Rev Clin Pharmacol. 2023 Jun 5:1-11. doi: 10.1080/17512433.2023.2219056. Online ahead of print.ABSTRACTINTRODUCTION: Around 80% of women suffer menopause-related symptoms that affect their daily activities and quality of life. Menopausal hormone therapy (MHT) has proven to be beneficial in relieving these symptoms. Nevertheless, only 20/30% of symptomatic women seek treatment. This has resulted in neglect of a generation of healthcare professionals' (HCPs) education in menopausal medicine and a reduction in the prescription of MHT in menopausal women for over two decades.AREAS COVERED: The aim of this article was to...
Source: Expert Review of Clinical Pharmacology - June 6, 2023 Category: Drugs & Pharmacology Authors: Serge Rozenberg Nick Panay Marco Gambacciani Antonio Cano Sarah Gray Katrin Schaudig Source Type: research
Breaking down barriers for prescribing and using hormone therapy for the treatment of menopausal symptoms: an experts' perspective
Expert Rev Clin Pharmacol. 2023 Jun 5:1-11. doi: 10.1080/17512433.2023.2219056. Online ahead of print.ABSTRACTINTRODUCTION: Around 80% of women suffer menopause-related symptoms that affect their daily activities and quality of life. Menopausal hormone therapy (MHT) has proven to be beneficial in relieving these symptoms. Nevertheless, only 20/30% of symptomatic women seek treatment. This has resulted in neglect of a generation of healthcare professionals' (HCPs) education in menopausal medicine and a reduction in the prescription of MHT in menopausal women for over two decades.AREAS COVERED: The aim of this article was to...
Source: Clinical Breast Cancer - June 6, 2023 Category: Cancer & Oncology Authors: Serge Rozenberg Nick Panay Marco Gambacciani Antonio Cano Sarah Gray Katrin Schaudig Source Type: research
Investigation of Factors Affecting Adherence to Adjuvant Hormone Therapy in Early-Stage Breast Cancer Patients: A Comprehensive Systematic Review
CONCLUSION: An effective psychological program that encourages positive views and beliefs about medication and management strategies for each therapy may be necessary to improve adherence to AHT. Social support and a sense of belonging can be enhanced through community participation and social media for better adherence to AHT. Patient-centered communication and appropriate recommendations by physicians may be attributable to better adherence outcomes. Findings from systematically organized factors that influence adherence to AHT may contribute to the establishment of intervention strategies to benefit patients with early-...
Source: Journal of Breast Cancer - June 5, 2023 Category: Cancer & Oncology Authors: Seongwoo Yang Seong Won Park Soong June Bae Sung Gwe Ahn Joon Jeong Kyounghoon Park Source Type: research
Hormonal therapies in females with blood disorders: thrombophilia, thrombosis, hemoglobinopathies, and anemias
Res Pract Thromb Haemost. 2023 Apr 24;7(4):100161. doi: 10.1016/j.rpth.2023.100161. eCollection 2023 May.ABSTRACTThere is widespread use of gonadal steroid hormone therapy for a variety of indications throughout the reproductive and postreproductive lifespan. These therapies may have particular benefits and specific risk among those with blood disorders, including inherited or acquired bleeding disorders, thrombophilia, thrombosis, or anemia. This clinical review is intended to provide a guidance for counseling and management of adolescent and adult biologic females with thrombophilic risk factors and/or thrombosis who req...
Source: Thrombosis and Haemostasis - June 5, 2023 Category: Hematology Authors: Maureen K Baldwin Bethany Samuelson Bannow Rachel P Rosovsky Nancy Sokkary Lakshmi V Srivaths Source Type: research
Gender-Affirming Hormone Therapy Among Transgender and Gender Diverse Patients Receiving Laser Hair Removal Prior to Gender-Affirming Surgery
J Drugs Dermatol. 2023 Jun 1;22(6):619-620. doi: 10.36849/JDD.7127.NO ABSTRACTPMID:37276162 | DOI:10.36849/JDD.7127 (Source: Journal of Drugs in Dermatology)
Source: Journal of Drugs in Dermatology - June 5, 2023 Category: Dermatology Authors: Gretchen Bellefeuille Katherine Plampton Rumbidzai Ngonyama Matthew Mansh Maria Hordinsky Ronda S Farah Source Type: research
GSE233909 The second Validation set of the 95GC in 2013.
Contributors : Yoshiaki Sota ; Ryo Tsunashima ; Yasuto NaoiSeries Type : Expression profiling by arrayOrganism : Homo sapiensThe aim of this study was to validate the efficacy of 95(GC) and compare it with that of 21(GC) (Oncotype DX) as well as to evaluate the combination of 95(GC) and 21(GC). DNA microarray data (gene expression) of ER-positive and node-negative breast cancer patients (n = 459) treated with adjuvant hormone therapy alone were classified with 95(GC) and 21(GC) (Recurrence Online at http://www.recurrenceonline.com/ ). 95(GC) classified the 459 patients into low-risk (n = 285; 10 year relapse-free surviv...
Source: GEO: Gene Expression Omnibus - June 3, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
Age but not menopausal status is linked to lower resting energy expenditure
CONCLUSIONS: We demonstrated that REEadj declines with age in women before late adulthood, also when controlling partially for genetic background, and that menopause may not contribute to this decline.PMID:37265230 | DOI:10.1210/clinem/dgad321 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - June 2, 2023 Category: Endocrinology Authors: Jari E Karppinen Petri Wiklund Johanna K Ihalainen Hanna-Kaarina Juppi Ville Isola Matti Hyv ärinen Essi K Ahokas Urho M Kujala Jari Laukkanen Juha J Hulmi Juha P Ahtiainen Sulin Cheng Eija K Laakkonen Source Type: research
Age but not menopausal status is linked to lower resting energy expenditure
CONCLUSIONS: We demonstrated that REEadj declines with age in women before late adulthood, also when controlling partially for genetic background, and that menopause may not contribute to this decline.PMID:37265230 | DOI:10.1210/clinem/dgad321 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - June 2, 2023 Category: Endocrinology Authors: Jari E Karppinen Petri Wiklund Johanna K Ihalainen Hanna-Kaarina Juppi Ville Isola Matti Hyv ärinen Essi K Ahokas Urho M Kujala Jari Laukkanen Juha J Hulmi Juha P Ahtiainen Sulin Cheng Eija K Laakkonen Source Type: research
Age but not menopausal status is linked to lower resting energy expenditure
CONCLUSIONS: We demonstrated that REEadj declines with age in women before late adulthood, also when controlling partially for genetic background, and that menopause may not contribute to this decline.PMID:37265230 | DOI:10.1210/clinem/dgad321 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - June 2, 2023 Category: Endocrinology Authors: Jari E Karppinen Petri Wiklund Johanna K Ihalainen Hanna-Kaarina Juppi Ville Isola Matti Hyv ärinen Essi K Ahokas Urho M Kujala Jari Laukkanen Juha J Hulmi Juha P Ahtiainen Sulin Cheng Eija K Laakkonen Source Type: research
Age but not menopausal status is linked to lower resting energy expenditure
CONCLUSIONS: We demonstrated that REEadj declines with age in women before late adulthood, also when controlling partially for genetic background, and that menopause may not contribute to this decline.PMID:37265230 | DOI:10.1210/clinem/dgad321 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - June 2, 2023 Category: Endocrinology Authors: Jari E Karppinen Petri Wiklund Johanna K Ihalainen Hanna-Kaarina Juppi Ville Isola Matti Hyv ärinen Essi K Ahokas Urho M Kujala Jari Laukkanen Juha J Hulmi Juha P Ahtiainen Sulin Cheng Eija K Laakkonen Source Type: research
