Effects of Hoodia Parviflora on satiety, abdominal obesity and weight in a group of overweight subjects: a randomized, blinded, placebo-controlled trial.
CONCLUSIONS: This study shows for the first time the simultaneous effect of H. Parviflora on weight loss, decreasing satiety, and improving fat mass, in particular VAT.
PMID: 32218424 [PubMed - as supplied by publisher] (Source: Minerva Gastroenterologica e Dietologica)
Source: Minerva Gastroenterologica e Dietologica - March 30, 2020 Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research
Oral Administration of Hoodia parviflora Alleviates Insulin Resistance and Nonalcoholic Steatohepatitis
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - October 20, 2019 Category: Nutrition Authors: Meir Mizrahi Ami Ben Ya'acov Tomer Adar Miriam Levy Sklair Svetlana Gaska Yaron Ilan Source Type: research
Evidence for the efficacy and safety of herbal weight loss preparations
Publication date: Available online 30 January 2019Source: Journal of Integrative MedicineAuthor(s): Rachael Farrington, Ian F. Musgrave, Roger W. ByardAbstractRising rates of obesity across the globe have been associated with an increase in the use of herbal preparations for weight control. However, the mechanisms of action for these substances are often not known, as is the potential for interaction with other herbal preparations or prescription pharmaceutical drugs. To investigate the reported efficacy and safety of herbal weight loss preparations, we conducted a review of the literature focusing on herbs that are most c...
Source: Journal of Integrative Medicine - January 31, 2019 Category: Complementary Medicine Source Type: research
Reinventing Hoodia: Peoples, Plants, and Patents in South Africa. Laura A. Â Foster, Seattle: University of Washington Press, 2017, 232 pp.
Medical Anthropology Quarterly, EarlyView. (Source: Medical Anthropology Quarterly)
Source: Medical Anthropology Quarterly - April 10, 2018 Category: International Medicine & Public Health Authors: DamienDroney Source Type: research
Metabolic Profiling of Hoodia, Chamomile, Terminalia Species and Evaluation of Commercial Preparations Using Ultrahigh-Performance Liquid Chromatography Quadrupole-Time-of-Flight Mass Spectrometry
Planta Med DOI: 10.1055/s-0043-109239Ultrahigh-performance liquid chromatography quadrupole-time-of-flight mass spectrometry (UHPLC-QToF-MS) profiling was used for the identification of marker compounds and generation of metabolic patterns that could be interrogated using chemometric modeling software. UHPLC-QToF-MS was used to generate comprehensive fingerprints of three botanicals (Hoodia, Terminalia, and chamomile), each having different classes of compounds. Detection of a broad range of ions was carried out in full scan mode in both positive and negative modes over the range m/z 100–1700 using high-resolution mass s...
Source: Planta Medica - April 28, 2017 Category: Drugs & Pharmacology Authors: Avula, Bharathi Wang, Yan-Hong Isaac, Giorgis Yuk, Jimmy Wrona, Mark Yu, Kate Khan, Ikhlas A. Tags: Original Papers Source Type: research
In vitro anti-HIV and antioxidant activity of Hoodia gordonii (Apocynaceae), a commercial plant product
Hoodia gordonii products are widely commercialized for anti-obesity purposes; however, minimal research is available on the other health properties demonstrated by this popular herbal ... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - October 24, 2016 Category: Complementary Medicine Authors: Petrina Kapewangolo, Michael Knott, Regina E. K. Shithigona, Sylvia L. Uusiku and Martha Kandawa-Schulz Source Type: research
The effect of two weeks ingestion of a bitter tastant mixture on energy intake in overweight females.
In conclusion, sustained exposure to these encapsulated bitter tastants did not significantly affect EI in overweight females.
PMID: 27522037 [PubMed - as supplied by publisher] (Source: Appetite)
Source: Appetite - August 9, 2016 Category: Nutrition Authors: Peters HP, Koppenol W, Schuring EA, Gouka R, Mela DJ, Blom WA Tags: Appetite Source Type: research
Obesity Phytotherapy: Review of Native Herbs Used in Traditional Medicine for Obesity
Obesity is an important disorders due to which 25 million deaths occur annually worldwide. Synthetic drugs for weight loss have low efficacy and high side effects. Apart from synthetic drugs in modern medicine, various other methods including the use of herbal medications are used to induce weight loss. Cambodia hoodia, green tea, Citrus aurantium, white beans, fenugreek, caffeine, ephedrine, capsaicin, yohimbine, chitosan, fitostreols, and guar gum have been studied in clinical trials and their effects have been confirmed. It seems necessary to study more to determine the effectiveness and safety of medicinal plants and h...
Source: Complementary Health Practice Review - May 25, 2016 Category: Complementary Medicine Authors: Bahmani, M., Eftekhari, Z., Saki, K., Fazeli-Moghadam, E., Jelodari, M., Rafieian-Kopaei, M. Tags: Topical Review Articles Source Type: research
Pregnane Glycosides from Cynanchum marnierianum Stimulate GLP-1 Secretion in STC-1 Cells
Planta MedDOI: 10.1055/s-0042-107675In the framework of the search for natural glucagon-like peptide-1 secretagogues, the bioassay-guided fractionation of the ethanolic extract from Cynanchum marnierianum led to the isolation of two new pregnane glycosides named marnieranosides A (1) and B (2). The structures were determined based on spectroscopic data and were established as 12β,20 S-O-dibenzoyl-pregn-6-en-5α,8β,14β,17β-tetraol-3-O-β-D-oleandropyranosyl-(1 → 4)-β-D-cymaropyranoside (1) and 12β,20R-O-dibenzoyl-pregn-6-en-5α,8β,14β-triol-3-O-β-D-oleandropyranosyl-(1 → 4)-β-D-canaropyranosyl-(1 â...
Source: Planta Medica - May 24, 2016 Category: Drugs & Pharmacology Authors: Tsoukalas, MichailMuller, Christian D.Lobstein, AnneliseUrbain, Aurélie Tags: Original Papers Source Type: research
New Dietary Supplements for Obesity: What We Currently Know
Abstract
Obesity and its associated cardiometabolic alterations currently are considered an epidemic; thus, their treatment is of major importance. The cornerstone for such treatment involves therapeutic lifestyle changes; however, the vast majority of cases fail and/or significant weight loss is maintained only in the short term because of lack of compliance. The popularity of dietary supplements for weight management has increased, and a wide variety of these products are available over the counter. However, the existing scientific evidence is insufficient to recommend their safe use. Hence, the purpose...
Source: Current Obesity Reports - April 5, 2016 Category: Eating Disorders and Weight Management Source Type: research
A review of commercially important African medicinal plants
Conclusion Despite a marked recent increase in the number of publications on indigenous medicinal plants and dietary supplements, Africa lags behind Europe and Asia in terms of the number of products that have been commercialised and the percentage of the flora that is utilised for international trade. There is a tremendous potential for developing new crops and new products but much work remains to be done to generate more focussed and relevant pre-clinical data and convincing proof of concept through clinical studies. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - October 24, 2015 Category: Drugs & Pharmacology Source Type: research
Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system.
Abstract
Hoodia gordonii is a plant species used traditionally in southern Africa to suppress appetite. Recently, it has been associated with a significant increase in blood pressure and pulse rate in women, suggesting sympathomimetic activity. The present study investigated the possible antidepressant-like effects of acute and repeated (15 days) administration of H. gordonii extract (25 and 50 mg/kg, po) to mice exposed to a forced swimming test (FST). Neurochemical analysis of brain monoamines was also carried out to determine the involvement of the monoaminergic system on these effects. Acute administra...
Source: Braz J Med Biol Res - December 14, 2014 Category: Research Authors: Citó MC, Silva MI, Santos LK, Fernandes ML, Melo FH, Aguiar JA, Lopes IS, Sousa PB, Vasconcelos SM, Macêdo DS, Sousa FC Tags: Braz J Med Biol Res Source Type: research
Metabolic disease: Weight loss herb targets GPCR
Nature Reviews Drug Discovery 13, 888 (2014).
doi:10.1038/nrd4498
Author: Sarah Crunkhorn
The African cactiform Hoodia gordonii exhibits anorexant properties, but the active components and molecular targets remain unclear. Here, a screen of 4,400 natural products identified Gordonoside F — a pregnane steroidal glycoside isolated from Hoodia gordonii — to activate GPR119, a GPCR highly (Source: Nature Reviews Drug Discovery)
Source: Nature Reviews Drug Discovery - November 14, 2014 Category: Drugs & Pharmacology Authors: Sarah Crunkhorn Tags: Research Highlight Source Type: research
Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system.
Abstract
Hoodia gordonii is a plant species used traditionally in southern Africa to suppress appetite. Recently, it has been associated with a significant increase in blood pressure and pulse rate in women, suggesting sympathomimetic activity. The present study investigated the possible antidepressant-like effects of acute and repeated (15 days) administration of H. gordonii extract (25 and 50 mg/kg, po) to mice exposed to a forced swimming test (FST). Neurochemical analysis of brain monoamines was also carried out to determine the involvement of the monoaminergic system on these effects. Acute administra...
Source: Braz J Med Biol Res - November 7, 2014 Category: Research Authors: Citó MC, Silva MI, Santos LK, Fernandes ML, Melo FH, Aguiar JA, Lopes IS, Sousa PB, Vasconcelos SM, Macêdo DS, Sousa FC Tags: Braz J Med Biol Res Source Type: research
