Urticaria: A Disorder With'a High Unmet Need for Treatment'Urticaria: A Disorder With'a High Unmet Need for Treatment '
Acute episodes of urticaria are more likely to have an identifiable trigger, while chronic episodes, which last more than six weeks, typically do not.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 3, 2022 Category: Allergy & Immunology Tags: Dermatology News Source Type: news
Got Hives? Here's How to Relieve Them at Home
Title: Got Hives? Here ' s How to Relieve Them at HomeCategory: Health NewsCreated: 2/20/2022 12:00:00 AMLast Editorial Review: 2/22/2022 12:00:00 AM (Source: MedicineNet Allergies General)
Source: MedicineNet Allergies General - February 22, 2022 Category: Allergy & Immunology Source Type: news
What Are Some Mast Cell Disorders?
Discussion
Mast cells (MCs) were first discovered by Paul Ehrlich in 1878. Previously in 1869, Nettleship and Tay described a toddler with chronic urticaria and a brown skin lesion which is believed to be the first reported case of mastocytosis. Urticaria pigmentosa was a term first used by Sangster in 1878, and in 1936 the term mastocytosis was used.
“Mast cells first evolved 500 million years ago in Ascidians (sea squirts), providing host innate immunity against bacteria and parasites….MCs gained additional functions regulating inflammation, wound healing, coagulation, adaptive immunity and acute allergic res...
Source: PediatricEducation.org - February 21, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Natalie Holles lands at freshly funded biotech startup focused initially on hives
Her first CEO role ended amid questions about a late-stage gene therapy. Now she's back with a smaller company and a big disease. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - February 16, 2022 Category: American Health Authors: Ron Leuty Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche reports good results in 2021
Basel, 3 February 2022Group sales increase 9%1 at constant exchange rates (CER); 8% in Swiss francsPharmaceuticals Divisionsales increase 3%; continued strong demand for newly launched medicines more than offsets impact of biosimilarsDiagnostics Divisionsales grow 29%; strong momentum in base business and continued high demand for COVID-19 testsMajor approvals for medicinessince the last quarter: United States: Susvimo and Vabysmo (age-related blindness)Europe: Gavreto (specific type of advanced lung cancer); Actemra/RoActemra (severe COVID-19); Ronapreve (non-hospitalised COVID-19 patients and prophylaxis)Major appro...
Source: Roche Investor Update - February 3, 2022 Category: Pharmaceuticals Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche reports good results in 2021
Basel, 3 February 2022Group sales increase 9%1 at constant exchange rates (CER); 8% in Swiss francsPharmaceuticals Divisionsales increase 3%; continued strong demand for newly launched medicines more than offsets impact of biosimilarsDiagnostics Divisionsales grow 29%; strong momentum in base business and continued high demand for COVID-19 testsMajor approvals for medicinessince the last quarter:United States: Susvimo and Vabysmo (age-related blindness)Europe: Gavreto (specific type of advanced lung cancer); Actemra/RoActemra (severe COVID-19); Ronapreve (non-hospitalised COVID-19 patients and prophylaxis)Major approvals f...
Source: Roche Media News - February 3, 2022 Category: Pharmaceuticals Source Type: news
EM Coach: Positively chilling
What caused this teen girl’s breakout of hives?
Question Stem
A 14-year-old girl is brought to the emergency department to be evaluated for diffuse hives (pictured below). They developed while the family was swimming in a cold lake where they were picnicking.
No one else in the family developed any symptoms. It took her parents 30 minutes to get her to the hospital, and her symptoms started to resolve by the time she arrived. Which of the following findings may be used to confirm the suspected diagnosis?
Question Answer Choices
A. Development of vesicles hours later
B. History of Raynaud’s phenomenon
C. Positive Alle...
Source: EPMonthly.com - February 1, 2022 Category: Emergency Medicine Authors: Jeffrey Lyles Source Type: news
U.S. FDA Approves CABENUVA (rilpivirine and cabotegravir) for Use Every Two Months, Expanding the Label of the First and Only Long-Acting HIV Treatment
TITUSVILLE, N.J., February 1, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the U.S. Food and Drug Administration (FDA) has approved an expanded label for CABENUVA (rilpivirine and cabotegravir) to be administered every two months for the treatment of HIV-1 in virologically suppressed adults (HIV-1 RNA less than 50 copies per milliliter [c/ml]) on a stable regimen, with no history of treatment failure, and with no known or suspected resistance to either rilpivirine or cabotegravir. The novel regimen was co-developed as part of a collaboration with ViiV Healthcare and builds on Janss...
Source: Johnson and Johnson - February 1, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
COVID-19 Severity Does Not Differ for Patients With Skin Conditions
WEDNESDAY, Dec. 15, 2021 -- For patients with psoriasis, vitiligo, atopic dermatitis (AD), and chronic urticaria (CU), COVID-19 severity does not differ, but treatment of COVID-19 may affect the course of skin disease, according to a letter to the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 15, 2021 Category: Pharmaceuticals Source Type: news
Honeybees use social distancing when mites threaten hives – study
Foraging bees keep away from centre of colony when infested with mites, find researchersIn the past 18 months humans have become all too familiar with the term “social distancing”. But it turns out we are not the only ones to give our peers a wide berth when our health may be at risk: research suggests honeybees do it too.Scientists have found that when a hive of honeybees is under threat from the miteVarroa destructor– a parasite linked to the collapse of honeybee colonies– the bees respond by changing the way they interact with one another.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - October 29, 2021 Category: Science Authors: Nicola Davis Tags: Bees Environment Insects Animals Wildlife Science Source Type: news
New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news
Learning to Live With CSU
Living with chronic spontaneous urticaria means finding out what works for you and avoiding triggers that seem to set off a flare. (Source: WebMD Health)
Source: WebMD Health - October 13, 2021 Category: Consumer Health News Source Type: news
Woman who had an IUD inserted claims it left her looking like a burn victim
Danelle Leseberg, 33, from Temecula, California, claimed she was left scared for her life and covered in painful hives after she was fitted with a hormonal IUD in August 2017. (Source: the Mail online | Health)
Source: the Mail online | Health - October 6, 2021 Category: Consumer Health News Source Type: news
