Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Panhypopituitarism, Diabetes Insipidus and Bone Pain - Is There a Systemic Disease Behind it?
Praxis (Bern 1994). 2024 Jan;113(1):23-26.ABSTRACTA 27-year-old man presented due to unilateral leg pain. He had a history of diabetes insipidus and panhypopituitarism. Laboratory analysis revealed hormonal undersupply. MRI showed a large contrast medium-absorbing mass in the pituitary gland extending into the hypothalamus. FDG-PET/CT examination revealed a hypermetabolic soft tissue lesion around the left femoral shaft. After biopsy of the lesion, a diagnosis of multisystemic Langerhans cell histiocytosis was made.PMID:38381107 (Source: Praxis)
Source: Praxis - February 21, 2024 Category: General Medicine Authors: Martina Bertschinger Lisa Sze Irene Bosma Corina Dommann-Scherrer Jeroen Goede Source Type: research

Orbital indeterminate cell histiocytosis
Orbit. 2024 Feb 19:1-5. doi: 10.1080/01676830.2024.2317301. Online ahead of print.ABSTRACTAn 8-year-old female presented to the oculoplastics clinic with 3 months of left upper eyelid fullness and edema. Examination showed a mass in the left anterior superior orbit with erythema. Imaging demonstrated a well-circumscribed superolateral orbital mass that was T1 hypointense and T2 hypo-to-iso intense with contrast enhancement. An incisional biopsy was performed via an upper lid crease incision. Histopathology showed aggregates of histiocytic cells with fibrosis and infiltration of eosinophils. Immunohistochemistry revealed po...
Source: Orbit - February 20, 2024 Category: Opthalmology Authors: Angela J Oh Connie M Sears Akhila A Vadivelan Brigitte N Gomperts Noah Federman Jonathan Said Kelsey A Roelofs Source Type: research

Orbital indeterminate cell histiocytosis
Orbit. 2024 Feb 19:1-5. doi: 10.1080/01676830.2024.2317301. Online ahead of print.ABSTRACTAn 8-year-old female presented to the oculoplastics clinic with 3 months of left upper eyelid fullness and edema. Examination showed a mass in the left anterior superior orbit with erythema. Imaging demonstrated a well-circumscribed superolateral orbital mass that was T1 hypointense and T2 hypo-to-iso intense with contrast enhancement. An incisional biopsy was performed via an upper lid crease incision. Histopathology showed aggregates of histiocytic cells with fibrosis and infiltration of eosinophils. Immunohistochemistry revealed po...
Source: Orbit - February 20, 2024 Category: Opthalmology Authors: Angela J Oh Connie M Sears Akhila A Vadivelan Brigitte N Gomperts Noah Federman Jonathan Said Kelsey A Roelofs Source Type: research