High Fat and Diet Induced Obesity
i-FectTM Delivers Again!Research shows that rats and humans on a high-fat diet (HFD) are less sensitive to satiety signals known to act via vagal afferent pathways. Impaired vagal afferent responsiveness to both gastric satiety hormones (CCK and leptin) and mechanical stimulation raises the possibility that changes in electrophysiological properties may be the underlying mechanism responsible for impaired vagal responsiveness to a wide variety of satiety signals.Potassium channels play a central role. To demonstrate this researchers used ouri-Fect siRNA Transfection Kit to silence TRESK and TASK1 to understand their impact...
Source: siRNA and DsiRNA Transfection Efficiency - September 16, 2019 Category: Neuroscience Tags: iFect in vivo siRNA intrathecal delivery of siRNA RNAi TRESK Source Type: news
High fat diet may cause brain changes, leading to increased desire to eat
In a study, mice who ate a high-fat diet experienced hypothalamic inflammation, causing changes to their microglial cells. Researchers say these physical changes caused neurological ones that may lead to obesity. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 9, 2019 Category: Consumer Health News Source Type: news
High-fat diets affect your brain, not just your physical appearance
High-fat diets contribute to irregularities in the hypothalamus region of the brain, which regulates body weight homeostasis and metabolism, a Yale study finds. (Source: Yale Science and Health News)
Source: Yale Science and Health News - September 5, 2019 Category: Universities & Medical Training Source Type: news
Our Food Systems Need Transformation
By Zoltán KálmánROME, Aug 28 2019 (IPS) The right to food is a universal human right. Yet, over 820 million people are going hungry, according the latest edition of the State of Food Security and Nutrition in the World (SOFI 2019). In addition, 2 billion people in the world are food insecure with great risk of malnutrition and poor health” 1.
Another report 2 describes the situation even more worrying: “At the global level, one person in three is malnourished today and one in two could be malnourished by 2030 in a business-as-usual scenario. While hunger remains a critical concern, malnutrition in all its forms (un...
Source: IPS Inter Press Service - Health - August 28, 2019 Category: International Medicine & Public Health Authors: Zoltan Kalman Tags: Climate Change Development & Aid Economy & Trade Environment Featured Food & Agriculture Global Headlines Health Human Rights Humanitarian Emergencies Inequity Natural Resources Poverty & SDGs TerraViva United Nations Source Type: news
The Keto Diet Is Popular, but Is It Good for You?
Low-carb, high-fat eating can lead to weight loss, but scientists debate the long-term effects on health. (Source: NYT Health)
Source: NYT Health - August 20, 2019 Category: Consumer Health News Authors: Anahad O ’Connor Tags: Obesity Diet and Nutrition Weight Diabetes Insulin Cholesterol Sugar Carbohydrates Exercise Calories Oils and Fats Vegetables Source Type: news
A Fatty Meal Might Affect How You Absorb CBD
Compared with fasting, the amount of CBD in the body was four times higher after the high-fat meal and the maximum amount in the blood was 14 times higher, the findings showed. (Source: WebMD Health)
Source: WebMD Health - August 16, 2019 Category: Consumer Health News Source Type: news
High-fat food turns off a signal in the brain that tells you when you are full
The study published in the Journal of Clinical Investigation suggests a previously unknown gut-brain connection that helps explain how extra servings lead to weight gain. (Source: the Mail online | Health)
Source: the Mail online | Health - August 13, 2019 Category: Consumer Health News Source Type: news
The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling
Hepatic activation of protein kinase C (PKC) isoforms by diacylglycerol (DAG) promotes insulin resistance and contributes to the development of type 2 diabetes (T2D). The closely related protein kinase D (PKD) isoforms act as effectors for DAG and PKC. Here, we showed that PKD3 was the predominant PKD isoform expressed in hepatocytes and was activated by lipid overload. PKD3 suppressed the activity of downstream insulin effectors including the kinase AKT and mechanistic target of rapamycin complex 1 and 2 (mTORC1 and mTORC2). Hepatic deletion of PKD3 in mice improved insulin-induced glucose tolerance. However, increased in...
Source: Signal Transduction Knowledge Environment - August 5, 2019 Category: Science Authors: Mayer, A. E., Löffler, M. C., Loza Valdes, A. E., Schmitz, W., El-Merahbi, R., Viera, J. T., Erk, M., Zhang, T., Braun, U., Heikenwalder, M., Leitges, M., Schulze, A., Sumara, G. Tags: STKE Research Articles Source Type: news
Keto Diet May Help Control Type 2 Diabetes
MONDAY, Aug. 5, 2019 -- The keto diet has plenty of weight-loss devotees who swear by the high fat, low-carb plan. Now, new research from India suggests it may benefit people with type 2 diabetes.
The study team found that people following a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 5, 2019 Category: General Medicine Source Type: news
Keto-Like Diet May Improve Cognition in MCI, Early Alzheimer's Keto-Like Diet May Improve Cognition in MCI, Early Alzheimer's
Changing the diet of individuals with mild cognitive impairment or early Alzheimer ' s to low-carb, high-fat ' ketogenic ' diet could positively affect cognitive function, early research shows.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - July 3, 2019 Category: Psychiatry Tags: Psychiatry News Source Type: news
Low-carb 'keto' diet ('Atkins-style') may modestly improve cognition in older adults
(Johns Hopkins Medicine) In a pilot study of 14 older adults with mild cognitive problems suggestive of early Alzheimer's disease, Johns Hopkins Medicine researchers report that a high-fat, low-carbohydrate diet may improve brain function and memory. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 27, 2019 Category: International Medicine & Public Health Source Type: news
Medical News Today: What to know about the endomorph diet
People with the endomorph body type can gain weight quickly. For this reason, they may wish to avoid processed foods and those with a high fat content. Certain types of exercise are also beneficial for people with endomorphic bodies. Learn more about the endomorph diet here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 27, 2019 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news
Junk Food Can Lower Sperm Count In Young Men, Harvard Study Finds
By Susan Scutti, CNN
(CNN) — Burgers, fries, pizza and high energy drinks impact testicular function in young men, new research suggests. Specifically, the sperm counts for men who typically eat “Western” meals of high fat foods were 25.6 million lower, on average, than the counts of men noshing on fish, chicken, fruits, vegetables and other more “prudent” foods, a new Harvard study found.
Sperm is the male reproductive cell. A man is considered to have a low sperm count if he has fewer than 15 million sperm per milliliter or less than 39 million sperm per ejaculation. A low sperm count can n...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 26, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health CNN Harvard Source Type: news
How Much Fat Do You Really Need?
MONDAY, June 17, 2019 -- With all the attention that the very high-fat Keto diet is getting, you might be wondering how much fat is healthy and how much your body really needs every day to thrive.
First, know that some fat is essential for most... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 17, 2019 Category: General Medicine Source Type: news
Obesity During Teen Years Tied to Stiffening of Arteries
THURSDAY, June 13, 2019 -- Persistently high fat mass during adolescence is associated with greater arterial stiffness, according to a study published online May 21 in The Lancet Child& Adolescent Health.
Frida Dangardt, M.D., from University... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 13, 2019 Category: Pharmaceuticals Source Type: news
