The Impact of Frailty on Palliative Care Receipt, Emergency Room Visits and Hospital Deaths in Cancer Patients: A Registry-Based Study
CONCLUSION: Frailty, as measured by the HFRS, significantly affects end-of-life cancer patients and should be considered in oncologic decision-making.PMID:37504346 | DOI:10.3390/curroncol30070486 (Source: Current Oncology)
Source: Current Oncology - July 28, 2023 Category: Cancer & Oncology Authors: Peter Strang Torbj örn Schultz Source Type: research

Time series analyses based on the joint lagged effect analysis of pollution and meteorological factors of hemorrhagic fever with renal syndrome and the construction of prediction model
ConclusionsThe SARIMA model may help to enhance the forecast of monthly HFRS incidence based on a long-range dataset. Our study had shown that environmental factors such as humidity and SO2 have a delayed effect on the occurrence of HFRS and that the effect of humidity can be influenced by SO2 and wind speed. Public health professionals should take greater care in controlling HFRS in low humidity, low windy conditions and 2 –3 days after SO2 levels above 200 μg/m3. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - July 24, 2023 Category: Tropical Medicine Authors: Ye Chen Source Type: research

Viruses, Vol. 15, Pages 1537: Cases of Hemorrhagic Fever with Renal Syndrome in Russia during 2000 & ndash;2022
Viruses, Vol. 15, Pages 1537: Cases of Hemorrhagic Fever with Renal Syndrome in Russia during 2000–2022 Viruses doi: 10.3390/v15071537 Authors: Evgeniy Tkachenko Svetlana Kurashova Alexandra Balkina Alexander Ivanov Mariya Egorova Oksana Leonovich Yulia Popova Rostislav Teodorovich Alla Belyakova Petr Tkachenko Dmitriy Trankvilevsky Ekaterina Blinova Aydar Ishmukhametov Tamara Dzagurova During 2000–2022, a total of 69 of Russia’s 85 administrative regions reported 164,580 hemorrhagic fever with renal syndrome (HFRS) cases, with an annual average rate o...
Source: Viruses - July 12, 2023 Category: Virology Authors: Evgeniy Tkachenko Svetlana Kurashova Alexandra Balkina Alexander Ivanov Mariya Egorova Oksana Leonovich Yulia Popova Rostislav Teodorovich Alla Belyakova Petr Tkachenko Dmitriy Trankvilevsky Ekaterina Blinova Aydar Ishmukhametov Tamara Dzagurova Tags: Review Source Type: research

Co-circulation and co-infection of hantaviruses and Wenzhou mammarenavirus in small mammals and humans in Jiangxi, China
Both Orthohantaviruses (HV) and Whenzhou Mammarenaviruses (WENV) are rodents borne viruses, allowing them to spread simultaneously in the same area and infect humans. To explore the potential threat of HV and WENV to public health safety, an environmental and laboratory investigation was conducted in 2020–2021, in Jiangxi province, China. A total of 461 small mammals of 7 species and paired sera from 43 suspected HFRS cases were collected from Jiangxi Province, China. Viral genomic RNA and specific antibodies against HV and WENV were detected to evaluate the epidemic situation of the two viruses. Hantaan virus (HTNV), se...
Source: Frontiers in Microbiology - July 12, 2023 Category: Microbiology Source Type: research

Logistic regression analysis of risk factors for hemorrhagic fever with renal syndrome complicated with acute pancreatitis
CONCLUSION: Our findings indicate that HFRS patients with a history of consuming alcohol, a high lym%, intense proteinuria, high levels of FDPs, and a low level of D-dimer might be more prone to the development of AP.KEY MESSAGESThis is the first report employing Logistic regression analysis methods for exploring the risk factors for HFRS complicated with AP in China.Many factors (most are laboratory parameters) were significantly associated with HFRS complicated with AP.We found that HFRS patients with a history of consuming alcohol, a high lym%, intense proteinuria, high levels of FDPs, and a low level of D-dimer might b...
Source: Annals of Medicine - July 11, 2023 Category: Internal Medicine Authors: Wenjie Wang Dongqing Fan Bin Quan Weishun Hou Jinsun Yang Source Type: research

Logistic regression analysis of risk factors for hemorrhagic fever with renal syndrome complicated with acute pancreatitis
CONCLUSION: Our findings indicate that HFRS patients with a history of consuming alcohol, a high lym%, intense proteinuria, high levels of FDPs, and a low level of D-dimer might be more prone to the development of AP.KEY MESSAGESThis is the first report employing Logistic regression analysis methods for exploring the risk factors for HFRS complicated with AP in China.Many factors (most are laboratory parameters) were significantly associated with HFRS complicated with AP.We found that HFRS patients with a history of consuming alcohol, a high lym%, intense proteinuria, high levels of FDPs, and a low level of D-dimer might b...
Source: Annals of Medicine - July 11, 2023 Category: Internal Medicine Authors: Wenjie Wang Dongqing Fan Bin Quan Weishun Hou Jinsun Yang Source Type: research

Identification and characterization of codon usage pattern and influencing factors in HFRS-causing hantaviruses
This study, although comprehensive, relies on in silico methods and thus necessitates experimental validation for more solid outcomes. Beyond the identified factors influencing viral behavior, there could be other yet undiscovered influences. These potential factors should be targets for further research to improve HFRS therapeutic strategies. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - July 10, 2023 Category: Allergy & Immunology Source Type: research

Using the Hospital Frailty Risk Score to assess mortality risk in older medical patients admitted to the intensive care unit
CMAJ Open. 2023 Jul 4;11(4):E607-E614. doi: 10.9778/cmajo.20220094. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Prognostic information at the time of hospital discharge can help guide goals-of-care discussions for future care. We sought to assess the association between the Hospital Frailty Risk Score (HFRS), which may highlight patients' risk of adverse outcomes at the time of hospital discharge, and in-hospital death among patients admitted to the intensive care unit (ICU) within 12 months of a previous hospital discharge.METHODS: We conducted a multicentre retrospective cohort study that included patients aged 75 years or ol...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Michael E Detsky Saeha Shin Michael Fralick Laveena Munshi Jacqueline M Kruser Katherine R Courtright Lauren Lapointe-Shaw Terence Tang Shail Rawal Janice L Kwan Adina Weinerman Fahad Razak Amol A Verma Source Type: research

Using the Hospital Frailty Risk Score to assess mortality risk in older medical patients admitted to the intensive care unit
CMAJ Open. 2023 Jul 4;11(4):E607-E614. doi: 10.9778/cmajo.20220094. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Prognostic information at the time of hospital discharge can help guide goals-of-care discussions for future care. We sought to assess the association between the Hospital Frailty Risk Score (HFRS), which may highlight patients' risk of adverse outcomes at the time of hospital discharge, and in-hospital death among patients admitted to the intensive care unit (ICU) within 12 months of a previous hospital discharge.METHODS: We conducted a multicentre retrospective cohort study that included patients aged 75 years or ol...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Michael E Detsky Saeha Shin Michael Fralick Laveena Munshi Jacqueline M Kruser Katherine R Courtright Lauren Lapointe-Shaw Terence Tang Shail Rawal Janice L Kwan Adina Weinerman Fahad Razak Amol A Verma Source Type: research

Using the Hospital Frailty Risk Score to assess mortality risk in older medical patients admitted to the intensive care unit
CMAJ Open. 2023 Jul 4;11(4):E607-E614. doi: 10.9778/cmajo.20220094. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Prognostic information at the time of hospital discharge can help guide goals-of-care discussions for future care. We sought to assess the association between the Hospital Frailty Risk Score (HFRS), which may highlight patients' risk of adverse outcomes at the time of hospital discharge, and in-hospital death among patients admitted to the intensive care unit (ICU) within 12 months of a previous hospital discharge.METHODS: We conducted a multicentre retrospective cohort study that included patients aged 75 years or ol...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Michael E Detsky Saeha Shin Michael Fralick Laveena Munshi Jacqueline M Kruser Katherine R Courtright Lauren Lapointe-Shaw Terence Tang Shail Rawal Janice L Kwan Adina Weinerman Fahad Razak Amol A Verma Source Type: research

Using the Hospital Frailty Risk Score to assess mortality risk in older medical patients admitted to the intensive care unit
CMAJ Open. 2023 Jul 4;11(4):E607-E614. doi: 10.9778/cmajo.20220094. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Prognostic information at the time of hospital discharge can help guide goals-of-care discussions for future care. We sought to assess the association between the Hospital Frailty Risk Score (HFRS), which may highlight patients' risk of adverse outcomes at the time of hospital discharge, and in-hospital death among patients admitted to the intensive care unit (ICU) within 12 months of a previous hospital discharge.METHODS: We conducted a multicentre retrospective cohort study that included patients aged 75 years or ol...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Michael E Detsky Saeha Shin Michael Fralick Laveena Munshi Jacqueline M Kruser Katherine R Courtright Lauren Lapointe-Shaw Terence Tang Shail Rawal Janice L Kwan Adina Weinerman Fahad Razak Amol A Verma Source Type: research

Using the Hospital Frailty Risk Score to assess mortality risk in older medical patients admitted to the intensive care unit
CMAJ Open. 2023 Jul 4;11(4):E607-E614. doi: 10.9778/cmajo.20220094. Print 2023 Jul-Aug.ABSTRACTBACKGROUND: Prognostic information at the time of hospital discharge can help guide goals-of-care discussions for future care. We sought to assess the association between the Hospital Frailty Risk Score (HFRS), which may highlight patients' risk of adverse outcomes at the time of hospital discharge, and in-hospital death among patients admitted to the intensive care unit (ICU) within 12 months of a previous hospital discharge.METHODS: We conducted a multicentre retrospective cohort study that included patients aged 75 years or ol...
Source: cmaj - July 4, 2023 Category: General Medicine Authors: Michael E Detsky Saeha Shin Michael Fralick Laveena Munshi Jacqueline M Kruser Katherine R Courtright Lauren Lapointe-Shaw Terence Tang Shail Rawal Janice L Kwan Adina Weinerman Fahad Razak Amol A Verma Source Type: research