Haemorrhagic Fever With Renal Syndrome (HFRS) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
In-cell Western assay to quantify infection with pathogenic orthohantavirus Puumala virus in replication kinetics and antiviral drug testing
Virus Res. 2023 Sep 29;337:199230. doi: 10.1016/j.virusres.2023.199230. Online ahead of print.ABSTRACTHemorrhagic fever with renal syndrome (HFRS) represents a serious zoonotic disease caused by orthohantaviruses in Eurasia. A specific antiviral therapy is not available. HFRS is characterized by acute kidney injury (AKI) with often massive proteinuria. Infection of kidney cells may contribute to the clinical picture. However, orthohantaviral replication in kidney cells is not well characterized. Therefore, we aimed to perform a reliable high-throughput assay that allows the quantification of infection rates and testing of ...
Source: Virus Research - September 30, 2023 Category: Virology Authors: Christian Nusshag Pamela Schreiber Josephine Uhrig Martin Zeier Ellen Krautkr ämer Source Type: research
In-cell Western assay to quantify infection with pathogenic orthohantavirus Puumala virus in replication kinetics and antiviral drug testing
Virus Res. 2023 Sep 29;337:199230. doi: 10.1016/j.virusres.2023.199230. Online ahead of print.ABSTRACTHemorrhagic fever with renal syndrome (HFRS) represents a serious zoonotic disease caused by orthohantaviruses in Eurasia. A specific antiviral therapy is not available. HFRS is characterized by acute kidney injury (AKI) with often massive proteinuria. Infection of kidney cells may contribute to the clinical picture. However, orthohantaviral replication in kidney cells is not well characterized. Therefore, we aimed to perform a reliable high-throughput assay that allows the quantification of infection rates and testing of ...
Source: Cell Research - September 30, 2023 Category: Cytology Authors: Christian Nusshag Pamela Schreiber Josephine Uhrig Martin Zeier Ellen Krautkr ämer Source Type: research
In-cell Western assay to quantify infection with pathogenic orthohantavirus Puumala virus in replication kinetics and antiviral drug testing
Virus Res. 2023 Sep 29;337:199230. doi: 10.1016/j.virusres.2023.199230. Online ahead of print.ABSTRACTHemorrhagic fever with renal syndrome (HFRS) represents a serious zoonotic disease caused by orthohantaviruses in Eurasia. A specific antiviral therapy is not available. HFRS is characterized by acute kidney injury (AKI) with often massive proteinuria. Infection of kidney cells may contribute to the clinical picture. However, orthohantaviral replication in kidney cells is not well characterized. Therefore, we aimed to perform a reliable high-throughput assay that allows the quantification of infection rates and testing of ...
Source: Virus Research - September 30, 2023 Category: Virology Authors: Christian Nusshag Pamela Schreiber Josephine Uhrig Martin Zeier Ellen Krautkr ämer Source Type: research
A case of pulmonary tuberculosis patient complicated with hemorrhagic fever with renal syndrome and scrub typhus in Yunnan, China: a case report
Hemorrhagic fever with renal syndrome (HFRS) caused by Orthohantavirus (OHV) and scrub typhus (ST) caused by Orientia tsutsugamushi (OT) are two infectious diseases prevalent in southwest China. Rodents are the n... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - September 27, 2023 Category: Infectious Diseases Authors: Hao Huang, Yichen Kong, Hongmin Yin, Zi Yang, Tilian Ren and Yunzhi Zhang Tags: Case Report Source Type: research
Impact of lanadfill characteristics on the atmospheric exposure to halogenated flame retardants in gulls
The objective of this study was to investigate how atmospheric exposure in ring-billed gulls to PBDEs and other HFRs is influenced by selected landfill characteristics (i.e., daily cover materials, waste types and tonnage). Miniature passive air samplers (PASs) combined with GPS dataloggers were deployed for ten days during six years on the back of wild-caught ring-billed gulls breeding in the Montreal area. Atmospheric levels of several PBDEs and other HFRs determined in PASs were found to increase with the presence probability of gulls in the two largest landfills using automotive shredder residues as daily cover materia...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Ana ïs Kerric Marc J Mazerolle Manon Sorais Jean-Fran çois Giroux Jonathan Verreault Source Type: research
Impact of lanadfill characteristics on the atmospheric exposure to halogenated flame retardants in gulls
The objective of this study was to investigate how atmospheric exposure in ring-billed gulls to PBDEs and other HFRs is influenced by selected landfill characteristics (i.e., daily cover materials, waste types and tonnage). Miniature passive air samplers (PASs) combined with GPS dataloggers were deployed for ten days during six years on the back of wild-caught ring-billed gulls breeding in the Montreal area. Atmospheric levels of several PBDEs and other HFRs determined in PASs were found to increase with the presence probability of gulls in the two largest landfills using automotive shredder residues as daily cover materia...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Ana ïs Kerric Marc J Mazerolle Manon Sorais Jean-Fran çois Giroux Jonathan Verreault Source Type: research
Impact of lanadfill characteristics on the atmospheric exposure to halogenated flame retardants in gulls
The objective of this study was to investigate how atmospheric exposure in ring-billed gulls to PBDEs and other HFRs is influenced by selected landfill characteristics (i.e., daily cover materials, waste types and tonnage). Miniature passive air samplers (PASs) combined with GPS dataloggers were deployed for ten days during six years on the back of wild-caught ring-billed gulls breeding in the Montreal area. Atmospheric levels of several PBDEs and other HFRs determined in PASs were found to increase with the presence probability of gulls in the two largest landfills using automotive shredder residues as daily cover materia...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Ana ïs Kerric Marc J Mazerolle Manon Sorais Jean-Fran çois Giroux Jonathan Verreault Source Type: research
Impact of lanadfill characteristics on the atmospheric exposure to halogenated flame retardants in gulls
The objective of this study was to investigate how atmospheric exposure in ring-billed gulls to PBDEs and other HFRs is influenced by selected landfill characteristics (i.e., daily cover materials, waste types and tonnage). Miniature passive air samplers (PASs) combined with GPS dataloggers were deployed for ten days during six years on the back of wild-caught ring-billed gulls breeding in the Montreal area. Atmospheric levels of several PBDEs and other HFRs determined in PASs were found to increase with the presence probability of gulls in the two largest landfills using automotive shredder residues as daily cover materia...
Source: Chemosphere - September 21, 2023 Category: Chemistry Authors: Ana ïs Kerric Marc J Mazerolle Manon Sorais Jean-Fran çois Giroux Jonathan Verreault Source Type: research
Frailty in aneurysmal subarachnoid hemorrhage: the risk analysis index
ConclusionThe RAI was robustly associated with poor functional outcomes in aSAH independent of established risk factors. (Source: Journal of Neurology)
Source: Journal of Neurology - September 20, 2023 Category: Neurology Source Type: research
Genetic diversity and molecular evolution of Seoul virus in Hebei province, China
Infect Genet Evol. 2023 Sep 15:105503. doi: 10.1016/j.meegid.2023.105503. Online ahead of print.ABSTRACTSeoul virus (SEOV) is a major pathogen which causes hemorrhagic fever with renal syndrome (HFRS), and is present all over the world. However, there are currently few long-term systematic studies of SEOV's phylogenetic and evolutionary mechanisms in epidemic areas. Thus, in this study, we used RT-PCR combined with NGS to obtain the genomes of six SEOV viruses from 1993, as well as 56 Hebei province-specific tissue samples from 1999 to 2022. Phylogenetic analysis showed that the SEOV samples could be divided into seven gro...
Source: Infection, Genetics and Evolution - September 17, 2023 Category: Genetics & Stem Cells Authors: Yamei Wei Yanan Cai Xu Han Zhanying Han Yanbo Zhang Yonggang Xu Qi Li Source Type: research
Genetic diversity and molecular evolution of Seoul virus in Hebei province, China
Infect Genet Evol. 2023 Sep 15:105503. doi: 10.1016/j.meegid.2023.105503. Online ahead of print.ABSTRACTSeoul virus (SEOV) is a major pathogen which causes hemorrhagic fever with renal syndrome (HFRS), and is present all over the world. However, there are currently few long-term systematic studies of SEOV's phylogenetic and evolutionary mechanisms in epidemic areas. Thus, in this study, we used RT-PCR combined with NGS to obtain the genomes of six SEOV viruses from 1993, as well as 56 Hebei province-specific tissue samples from 1999 to 2022. Phylogenetic analysis showed that the SEOV samples could be divided into seven gro...
Source: Infection, Genetics and Evolution - September 17, 2023 Category: Genetics & Stem Cells Authors: Yamei Wei Yanan Cai Xu Han Zhanying Han Yanbo Zhang Yonggang Xu Qi Li Source Type: research
Genetic diversity and molecular evolution of Seoul virus in Hebei province, China
Infect Genet Evol. 2023 Sep 16;114:105503. doi: 10.1016/j.meegid.2023.105503. Online ahead of print.ABSTRACTSeoul virus (SEOV) is a major pathogen which causes hemorrhagic fever with renal syndrome (HFRS), and is present all over the world. However, there are currently few long-term systematic studies of SEOV's phylogenetic and evolutionary mechanisms in epidemic areas. Thus, in this study, we used RT-PCR combined with NGS to obtain the genomes of six SEOV viruses from 1993, as well as 56 Hebei province-specific tissue samples from 1999 to 2022. Phylogenetic analysis showed that the SEOV samples could be divided into seven...
Source: Infection, Genetics and Evolution - September 17, 2023 Category: Genetics & Stem Cells Authors: Yamei Wei Yanan Cai Xu Han Zhanying Han Yanbo Zhang Yonggang Xu Qi Li Source Type: research
Impact of Frailty on Emergency Department Encounters for Cardiovascular Disease: A Retrospective Cohort Study
Data are limited on whether the causes of emergency department (ED) encounters for cardiovascular diseases (CVDs) and associated clinical outcomes vary by frailty status. Using the United States Nationwide ED Sample, selected CVD encounters (acute myocardial infarction [AMI], ischemic stroke, atrial fibrillation [AF], heart failure [HF], pulmonary embolism, cardiac arrest, and hemorrhagic stroke) were stratified by hospital frailty risk score (HFRS). Logistic regression was used to determine the adjusted odds ratios (aORs) and 95% confidence intervals (CIs) of ED mortality among the different frailty groups. (Source: The A...
Source: The American Journal of Cardiology - September 12, 2023 Category: Cardiology Authors: Balamrit Singh Sokhal, Andrija Mateti ć, Abhishek Abhishek, Amitava Banerjee, Richard Partington, Edward Roddy, Muhammad Rashid, Christian David Mallen, Mamas Andreas Mamas Source Type: research
Predictive Value of CD4 < sup > + < /sup > CD8 < sup > + < /sup > Double Positive T Cells for the Severity of Hemorrhagic Fever with Renal Syndrome
CONCLUSIONS: The level of DP T cells is associated with HFRS severity, suggesting that it may be a potent indicator for the course of this disorder.PMID:37652222 | DOI:10.1016/j.clinbiochem.2023.110643 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - August 31, 2023 Category: Biochemistry Authors: Han-Dong Zhao Ju-Jun Sun Tong-Bo Yu Hong-Li Liu Source Type: research
Predictive Value of CD4 < sup > + < /sup > CD8 < sup > + < /sup > Double Positive T Cells for the Severity of Hemorrhagic Fever with Renal Syndrome
CONCLUSIONS: The level of DP T cells is associated with HFRS severity, suggesting that it may be a potent indicator for the course of this disorder.PMID:37652222 | DOI:10.1016/j.clinbiochem.2023.110643 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - August 31, 2023 Category: Biochemistry Authors: Han-Dong Zhao Ju-Jun Sun Tong-Bo Yu Hong-Li Liu Source Type: research