Haemorrhagic Fever With Renal Syndrome (HFRS) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Case Report: Hemorrhagic Fever with Renal Syndrome Complicated by Bilateral Subdural Hematoma
Am J Trop Med Hyg. 2023 Nov 6:tpmd230248. doi: 10.4269/ajtmh.23-0248. Online ahead of print.ABSTRACTHemorrhagic fever with renal syndrome (HFRS) is an acute, natural focal disease worldwide. Bilateral subdural hematoma (BSH) is a rare occurrence in patients with HFRS. A 51-year-old man was admitted with fever, headache, lower back pain, and reduced urine volume. The patient was diagnosed with HFRS accompanied by BSH, as evidenced by IgM and IgG antibodies for hantavirus that were positive, and abnormal blood test results and computed tomographic head scan. He recovered and was discharged after symptomatic treatment. Hemorr...
Source: The American Journal of Tropical Medicine and Hygiene - November 6, 2023 Category: Tropical Medicine Authors: Wei Xiao Yanli Tang Lie Chen Zheyong Jia Tao Mei Source Type: research

Case Report: Hemorrhagic Fever with Renal Syndrome Complicated by Bilateral Subdural Hematoma
Am J Trop Med Hyg. 2023 Nov 6:tpmd230248. doi: 10.4269/ajtmh.23-0248. Online ahead of print.ABSTRACTHemorrhagic fever with renal syndrome (HFRS) is an acute, natural focal disease worldwide. Bilateral subdural hematoma (BSH) is a rare occurrence in patients with HFRS. A 51-year-old man was admitted with fever, headache, lower back pain, and reduced urine volume. The patient was diagnosed with HFRS accompanied by BSH, as evidenced by IgM and IgG antibodies for hantavirus that were positive, and abnormal blood test results and computed tomographic head scan. He recovered and was discharged after symptomatic treatment. Hemorr...
Source: Am J Trop Med Hyg - November 6, 2023 Category: Infectious Diseases Authors: Wei Xiao Yanli Tang Lie Chen Zheyong Jia Tao Mei Source Type: research

Single fraction and hypofractionated radiosurgery for perioptic meningiomas —tumor control and visual outcomes: a systematic review and meta-analysis
AbstractPerioptic meningiomas, defined as those that are less than 3 mm from the optic apparatus, are challenging to treat with stereotactic radiosurgery (SRS). Tumor control must be weighed against the risk of radiation-induced optic neuropathy (RION), as both tumor progression and RION can lead to visual decline. We performed a systematic review and meta-analysis of single fraction SRS and hypofractionated radiosurgery (hfRS) for perioptic meningiomas, evaluating tumor control and visual preservation rates. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we reviewed art...
Source: Neurosurgical Review - October 28, 2023 Category: Neurosurgery Source Type: research

Diversity and Genetic Characterization of Orthohantavirus from Small Mammals and Humans during 2012-2022 in Hubei Province, Central China
Acta Trop. 2023 Oct 20:107046. doi: 10.1016/j.actatropica.2023.107046. Online ahead of print.ABSTRACTHemorrhagic fever with renal syndrome (HFRS) is a significant public health problem in Hubei Province, China, where a novel strain of orthohantavirus, HV004, was reported in 2012. However, no systematic study has investigated the prevalence and variation of orthohantavirus in rodents and humans. Herein, 2137 small mammals were collected from ten HFRS epidemic areas in Hubei Province from 2012 to 2022, and 143 serum samples from patients with suspected hemorrhagic fever were collected from two hospitals from 2017 to 2021. Or...
Source: Acta Tropica - October 22, 2023 Category: Infectious Diseases Authors: Jin-Tao Chen Jian-Bo Zhan Ming-Chao Zhu Kai-Ji Li Man-Qing Liu Bin Hu Kun Cai Hai-Rong Xiong Shu-Liang Chen Wei-Long Tan Liang-Jun Chen Wei Hou Source Type: research

Hantavirus: an overview and advancements in therapeutic approaches for infection
Hantaviruses are a significant and emerging global public health threat, impacting more than 200,000 individuals worldwide each year. The single-stranded RNA viruses belong to the Hantaviridae family and are responsible for causing two acute febrile diseases in humans: Hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). Currently, there are no licensed treatments or vaccines available globally for HTNV infection. Various candidate drugs have shown efficacy in increasing survival rates during the early stages of HTNV infection. Some of these drugs include lactoferrin, ribavirin, ETAR, favip...
Source: Frontiers in Microbiology - October 12, 2023 Category: Microbiology Source Type: research

In-cell Western assay to quantify infection with pathogenic orthohantavirus Puumala virus in replication kinetics and antiviral drug testing
Virus Res. 2023 Sep 28:199230. doi: 10.1016/j.virusres.2023.199230. Online ahead of print.ABSTRACTHemorrhagic fever with renal syndrome (HFRS) represents a serious zoonotic disease caused by orthohantaviruses in Eurasia. A specific antiviral therapy is not available. HFRS is characterized by acute kidney injury (AKI) with often massive proteinuria. Infection of kidney cells may contribute to the clinical picture. However, orthohantaviral replication in kidney cells is not well characterized. Therefore, we aimed to perform a reliable high-throughput assay that allows the quantification of infection rates and testing of anti...
Source: Cell Research - September 30, 2023 Category: Cytology Authors: Christian Nusshag Pamela Schreiber Josephine Uhrig Martin Zeier Ellen Krautkr ämer Source Type: research