Partly unequal receipt of healthcare in last month of life in amyotrophic lateral sclerosis: a retrospective cohort study of the Stockholm region
CONCLUSIONS: The results indicate partly unequal distribution of palliative care, however the actual, individual preferences cannot be deducted from registry studies. All patients with ALS should be offered SPC when needed.KEY MESSAGE: This register study shows that receipt of SPC in patients with ALS is equal in relation to gender, socioeconomic standing, frailty, and age <75 years, while those ≥75 years, with dementia, or residing in NH were somewhat less likely to receive SPC. Receipt of SPC reduces ER visits and acute hospital admissions.PMID:38371486 | PMC:PMC10870957 | DOI:10.48101/ujms.v129.9856 (Source: Upsala...
Source: Upsala Journal of Medical Sciences - February 19, 2024 Category: General Medicine Authors: Peter Strang Torbj örn Schultz Anneli Ozanne Source Type: research

Partly unequal receipt of healthcare in last month of life in amyotrophic lateral sclerosis: a retrospective cohort study of the Stockholm region
CONCLUSIONS: The results indicate partly unequal distribution of palliative care, however the actual, individual preferences cannot be deducted from registry studies. All patients with ALS should be offered SPC when needed.KEY MESSAGE: This register study shows that receipt of SPC in patients with ALS is equal in relation to gender, socioeconomic standing, frailty, and age <75 years, while those ≥75 years, with dementia, or residing in NH were somewhat less likely to receive SPC. Receipt of SPC reduces ER visits and acute hospital admissions.PMID:38371486 | PMC:PMC10870957 | DOI:10.48101/ujms.v129.9856 (Source: Upsala...
Source: Upsala Journal of Medical Sciences - February 19, 2024 Category: General Medicine Authors: Peter Strang Torbj örn Schultz Anneli Ozanne Source Type: research

Partly unequal receipt of healthcare in last month of life in amyotrophic lateral sclerosis: a retrospective cohort study of the Stockholm region
CONCLUSIONS: The results indicate partly unequal distribution of palliative care, however the actual, individual preferences cannot be deducted from registry studies. All patients with ALS should be offered SPC when needed.KEY MESSAGE: This register study shows that receipt of SPC in patients with ALS is equal in relation to gender, socioeconomic standing, frailty, and age <75 years, while those ≥75 years, with dementia, or residing in NH were somewhat less likely to receive SPC. Receipt of SPC reduces ER visits and acute hospital admissions.PMID:38371486 | PMC:PMC10870957 | DOI:10.48101/ujms.v129.9856 (Source: Upsala...
Source: Upsala Journal of Medical Sciences - February 19, 2024 Category: General Medicine Authors: Peter Strang Torbj örn Schultz Anneli Ozanne Source Type: research

Partly unequal receipt of healthcare in last month of life in amyotrophic lateral sclerosis: a retrospective cohort study of the Stockholm region
CONCLUSIONS: The results indicate partly unequal distribution of palliative care, however the actual, individual preferences cannot be deducted from registry studies. All patients with ALS should be offered SPC when needed.KEY MESSAGE: This register study shows that receipt of SPC in patients with ALS is equal in relation to gender, socioeconomic standing, frailty, and age <75 years, while those ≥75 years, with dementia, or residing in NH were somewhat less likely to receive SPC. Receipt of SPC reduces ER visits and acute hospital admissions.PMID:38371486 | PMC:PMC10870957 | DOI:10.48101/ujms.v129.9856 (Source: Upsala...
Source: Upsala Journal of Medical Sciences - February 19, 2024 Category: General Medicine Authors: Peter Strang Torbj örn Schultz Anneli Ozanne Source Type: research

Partly unequal receipt of healthcare in last month of life in amyotrophic lateral sclerosis: a retrospective cohort study of the Stockholm region
CONCLUSIONS: The results indicate partly unequal distribution of palliative care, however the actual, individual preferences cannot be deducted from registry studies. All patients with ALS should be offered SPC when needed.KEY MESSAGE: This register study shows that receipt of SPC in patients with ALS is equal in relation to gender, socioeconomic standing, frailty, and age <75 years, while those ≥75 years, with dementia, or residing in NH were somewhat less likely to receive SPC. Receipt of SPC reduces ER visits and acute hospital admissions.PMID:38371486 | PMC:PMC10870957 | DOI:10.48101/ujms.v129.9856 (Source: Upsala...
Source: Upsala Journal of Medical Sciences - February 19, 2024 Category: General Medicine Authors: Peter Strang Torbj örn Schultz Anneli Ozanne Source Type: research

Partly unequal receipt of healthcare in last month of life in amyotrophic lateral sclerosis: a retrospective cohort study of the Stockholm region
CONCLUSIONS: The results indicate partly unequal distribution of palliative care, however the actual, individual preferences cannot be deducted from registry studies. All patients with ALS should be offered SPC when needed.KEY MESSAGE: This register study shows that receipt of SPC in patients with ALS is equal in relation to gender, socioeconomic standing, frailty, and age <75 years, while those ≥75 years, with dementia, or residing in NH were somewhat less likely to receive SPC. Receipt of SPC reduces ER visits and acute hospital admissions.PMID:38371486 | PMC:PMC10870957 | DOI:10.48101/ujms.v129.9856 (Source: Upsala...
Source: Upsala Journal of Medical Sciences - February 19, 2024 Category: General Medicine Authors: Peter Strang Torbj örn Schultz Anneli Ozanne Source Type: research

Partly unequal receipt of healthcare in last month of life in amyotrophic lateral sclerosis: a retrospective cohort study of the Stockholm region
CONCLUSIONS: The results indicate partly unequal distribution of palliative care, however the actual, individual preferences cannot be deducted from registry studies. All patients with ALS should be offered SPC when needed.KEY MESSAGE: This register study shows that receipt of SPC in patients with ALS is equal in relation to gender, socioeconomic standing, frailty, and age <75 years, while those ≥75 years, with dementia, or residing in NH were somewhat less likely to receive SPC. Receipt of SPC reduces ER visits and acute hospital admissions.PMID:38371486 | PMC:PMC10870957 | DOI:10.48101/ujms.v129.9856 (Source: Upsala...
Source: Upsala Journal of Medical Sciences - February 19, 2024 Category: General Medicine Authors: Peter Strang Torbj örn Schultz Anneli Ozanne Source Type: research

Viruses, Vol. 16, Pages 306: Rosuvastatin as a Supplemental Treatment for the Clinical Symptoms of Nephropathia Epidemica: A Pilot Clinical Study
This study aimed to assess the impact of rosuvastatin on the clinical and laboratory results of NE. A total of 61 NE patients and 30 controls were included in this study; 22 NE patients and 7 controls received a daily dose of rosuvastatin (10 mg) for ten consecutive days. Serum samples were collected on days 1, 5, and 10 after admission to the hospital. These samples were analyzed to determine the levels of lipids, cytokines, and kidney toxicity markers. Our findings indicate that rosuvastatin reduced the duration of the second wave of fever and alleviated back pain and headache symptoms. Additionally, low-density lipoprot...
Source: Viruses - February 17, 2024 Category: Virology Authors: Venera Shakirova Maria Markelova Yuriy Davidyuk Robert J. Stott-Marshall Toshana L. Foster Svetlana Khaiboullina Albert Rizvanov Ekaterina Martynova Tags: Article Source Type: research

Indoor environment, physiological factors, and diet as predictors of halogenated flame retardant levels in stool and plasma of children from a Canadian cohort
Chemosphere. 2024 Feb 10:141443. doi: 10.1016/j.chemosphere.2024.141443. Online ahead of print.ABSTRACTExposure to halogenated flame retardants (HFRs) has been associated with various adverse effects on human health. Human exposure to HFRs mainly occurs through diet, ingesting contaminated dust, and inhaling contaminated air. Understanding and characterizing the variables linked to these exposure pathways is essential for developing effective risk assessment and mitigation strategies. We investigated indoor environment quality, physiological factors, and diet as potential predictors of HFRs concentration in children's plas...
Source: Chemosphere - February 12, 2024 Category: Chemistry Authors: Guillaume Martinez Jiping Zhu Larissa Takser Andrea A Baccarelli Jean-Philippe Bellenger Source Type: research

Indoor environment, physiological factors, and diet as predictors of halogenated flame retardant levels in stool and plasma of children from a Canadian cohort
Chemosphere. 2024 Feb 10:141443. doi: 10.1016/j.chemosphere.2024.141443. Online ahead of print.ABSTRACTExposure to halogenated flame retardants (HFRs) has been associated with various adverse effects on human health. Human exposure to HFRs mainly occurs through diet, ingesting contaminated dust, and inhaling contaminated air. Understanding and characterizing the variables linked to these exposure pathways is essential for developing effective risk assessment and mitigation strategies. We investigated indoor environment quality, physiological factors, and diet as potential predictors of HFRs concentration in children's plas...
Source: Chemosphere - February 12, 2024 Category: Chemistry Authors: Guillaume Martinez Jiping Zhu Larissa Takser Andrea A Baccarelli Jean-Philippe Bellenger Source Type: research

Cancers, Vol. 16, Pages 749: Survival Outcomes in Older Women with Oestrogen-Receptor-Positive Early-Stage Breast Cancer: Primary Endocrine Therapy vs. Surgery by Comorbidity and Frailty Levels
This study used UK secondary data to analyse older female patients from 2000 to 2016. Patients were censored until 31 May 2019 and grouped by the Charlson comorbidity index (CCI) and hospital frailty risk score (HFRS). Cox regression models compared all-cause and breast cancer-specific mortality between PET and surgery within each group, adjusting for patient preferences and covariates. Sensitivity analyses accounted for competing risks. There were 23,109 patients included. The hazard ratio (HR) comparing PET to surgery for overall survival decreased significantly from 2.1 (95%CI: 2.0, 2.2) to 1.2 (95%CI: 1.1, 1.5) with in...
Source: Cancers - February 11, 2024 Category: Cancer & Oncology Authors: Yubo Wang Douglas Steinke Sean P. Gavan Teng-Chou Chen Matthew J. Carr Darren M. Ashcroft Kwok-Leung Cheung Li-Chia Chen Tags: Article Source Type: research

Viruses, Vol. 16, Pages 145: Epidemiology of Hemorrhagic Fever with Renal Syndrome and Host Surveillance in Zhejiang Province, China, 1990 & ndash;2021
In this study, we aimed to explore the changing epidemiology of HFRS cases and the dynamics of hantavirus hosts in Zhejiang Province. Joinpoint regression was used to analyze long-term trends in the incidence of HFRS. The comparison of animal density at different stages was conducted using the Mann&amp;ndash;Whitney Test. A comparison of HV carriage rates between stages and species was performed using the chi-square test. The incidence of HFRS shows a continuous downward trend. Cases are widely distributed in all counties of Zhejiang Province except Shengsi County. There was a high incidence belt from west to east, wit...
Source: Viruses - January 19, 2024 Category: Virology Authors: Fan Su Ying Liu Feng Ling Rong Zhang Zhen Wang Jimin Sun Tags: Article Source Type: research

Levels of peripheral blood routine, biochemical and coagulation parameters in patients with hemorrhagic fever with renal syndrome and their relationship with prognosis: an observational cohort study
Hantaan virus (HTNV), Seoul virus (SEOV) and Puumala virus (PUUV) are major serotypes of the Hantavirus, which can cause hemorrhagic fever with renal syndrome (HFRS). The pathophysiology of HFRS in humans is c... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - January 11, 2024 Category: Infectious Diseases Authors: Wen-jing Chen, Hong Du, Hai-feng Hu, Jian-qi Lian, Hong Jiang, Jing Li, Yan-ping Chen, Ying Zhang and Ping-zhong Wang Tags: Research Source Type: research

Population frailty trends by education and income levels over a period of 30 years: findings from Swedish registry data
Conclusion Over time, education and income levels were more equally represented among the frail population in more recent years. More equitable distribution over time may suggest improvement in health disparities, though more work is needed. The overall increase in frailty and unchanged association with mortality indicates that additional research is needed to better understand how to best support the growing ageing population. This would then support the long-term viability of the healthcare system. (Source: Journal of Epidemiology and Community Health)
Source: Journal of Epidemiology and Community Health - January 10, 2024 Category: Epidemiology Authors: Wennberg, A., Tao, Y., Ek, S., Modig, K. Tags: Open access Original research Source Type: research

Patient Frailty is Correlated with Increased Adverse Events and Costs After Revision Total Hip Arthroplasty
This study examined the relationship between the Hospital Frailty Risk Scores (HFRS), postoperative outcomes, and cost profiles following rTHA. (Source: The Journal of Arthroplasty)
Source: The Journal of Arthroplasty - December 20, 2023 Category: Orthopaedics Authors: Michael K. Tram, Ameer Tabbaa, Akshay Lakra, Afshin A. Anoushiravani, Thomas Bernasek, Steven T. Lyons, Casey M. O ’Connor Source Type: research