The importance of cell uptake in photothermal treatments mediated by biomimetic magnetic nanoparticles
In this study, three different situations for photothermal treatments have been simulated to disentangle the effect of BMNPs cell uptake on cell viability after photothermal treatments. Human hepatoblastoma (HepG2) cell line was treated with suspensions of BMNPs, and protocols were developed to have only intracellular BMNPs, only extracellular BMNPs or both, followed by photothermal exposure of the treated cell cultures. Our data demonstrate that: (1) Although the heating efficiency of the photothermal agent is not altered by its location (intra/extracellular), the intracellular location of BMNPs is crucial to ensure the c...
Source: Colloids and Surfaces - December 31, 2023 Category: Biotechnology Authors: M L ázaro P Lupi áñez A Sola-Leyva T Pozo-Gualda F Oltolina M Jimenez-Carretero C Jimenez-Lopez M P Carrasco-Jim énez G R Iglesias Source Type: research
The importance of cell uptake in photothermal treatments mediated by biomimetic magnetic nanoparticles
In this study, three different situations for photothermal treatments have been simulated to disentangle the effect of BMNPs cell uptake on cell viability after photothermal treatments. Human hepatoblastoma (HepG2) cell line was treated with suspensions of BMNPs, and protocols were developed to have only intracellular BMNPs, only extracellular BMNPs or both, followed by photothermal exposure of the treated cell cultures. Our data demonstrate that: (1) Although the heating efficiency of the photothermal agent is not altered by its location (intra/extracellular), the intracellular location of BMNPs is crucial to ensure the c...
Source: Colloids and Surfaces - December 31, 2023 Category: Biotechnology Authors: M L ázaro P Lupi áñez A Sola-Leyva T Pozo-Gualda F Oltolina M Jimenez-Carretero C Jimenez-Lopez M P Carrasco-Jim énez G R Iglesias Source Type: research
The importance of cell uptake in photothermal treatments mediated by biomimetic magnetic nanoparticles
In this study, three different situations for photothermal treatments have been simulated to disentangle the effect of BMNPs cell uptake on cell viability after photothermal treatments. Human hepatoblastoma (HepG2) cell line was treated with suspensions of BMNPs, and protocols were developed to have only intracellular BMNPs, only extracellular BMNPs or both, followed by photothermal exposure of the treated cell cultures. Our data demonstrate that: (1) Although the heating efficiency of the photothermal agent is not altered by its location (intra/extracellular), the intracellular location of BMNPs is crucial to ensure the c...
Source: Colloids and Surfaces - December 31, 2023 Category: Biotechnology Authors: M L ázaro P Lupi áñez A Sola-Leyva T Pozo-Gualda F Oltolina M Jimenez-Carretero C Jimenez-Lopez M P Carrasco-Jim énez G R Iglesias Source Type: research
An update on diagnosis and treatment of hepatoblastoma
Biosci Trends. 2023 Dec 23. doi: 10.5582/bst.2023.01311. Online ahead of print.ABSTRACTHepatoblastoma (HB) remains the most common paediatric liver tumour and survival in children with hepatoblastoma has improved considerably since the advent of sequential surgical regimens of chemotherapy based on platinum-based chemotherapeutic agents in the 1980s. With the advent of modern diagnostic imaging and pathology techniques, new preoperative chemotherapy regimens and the maturation of surgical techniques, new diagnostic and treatment options for patients with hepatoblastoma have emerged and international collaborations are inve...
Source: BioScience Trends - December 24, 2023 Category: Biomedical Science Authors: Yinbiao Cao Shurui Wu Haowen Tang Source Type: research
