What is PAN?
Discussion
Vasculitis is an inflammation of the blood vessels. Often, the term implies the arterial vessels, but venous and capillary vessels can be affected. The nomenclature to describe vasculitis and its classification have varied over time. Arterial vessel size is one method and some more common entities include:
Small vessel, mainly
Granulomatous – granulomatosis with polyangiitis (aka Wegener’s granulomatosis), eosinophilic granulomatosis with polyangiitis (aka Churg Strauss syndrome)
Nongranulomatous – Henoch-Schonlein purpura (HSP), microscopic polyangiitis
Medium vessel, mainly
Childhood sys...
Source: PediatricEducation.org - February 27, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Hepatitis B Foundation calls reports J & J is deprioritizing its hepatitis therapy efforts 'disappointing'
"We entered 2023 with a robust and diverse pipeline of potential treatments for hepatitis B, but this news demonstrates the precarious nature of the pipeline." (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - February 13, 2023 Category: American Health Authors: John George Source Type: news
Artificial Liver Support Systems for HBV-associated ACLF Artificial Liver Support Systems for HBV-associated ACLF
Can artificial liver support systems improve short-term survival rates in patients with acute-on-chronic liver failure due to hepatitis B virus infection?Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 6, 2023 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Janssen Announces Unblinding of Phase 3 CARTITUDE-4 Study of CARVYKTI ® (cilta-cel) as Primary Endpoint Met in Treatment of Patients with Relapsed and Refractory Multiple Myeloma
RARITAN, New Jersey, January 27, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Phase 3 CARTITUDE-4 study evaluating CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) versus pomalidomide, bortezomib, and dexamethasone (PVd) or daratumumab, pomalidomide, and dexamethasone (DPd) for the treatment of patients with relapsed and lenalidomide-refractory multiple myeloma met its primary endpoint of significant improvement in progression-free survival (PFS) at the first pre-specified interim analysis. As a result of meeting the primary endpoint, the Independent Data Monitoring Commi...
Source: Johnson and Johnson - January 27, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche ’s Tecentriq plus Avastin is the first treatment combination to reduce the risk of cancer returning in people with certain types of early-stage liver cancer in a Phase III trial
Pivotal Phase III IMbrave050 study investigatingTecentriq plusAvastin in people with early-stage hepatocellular carcinoma (HCC) at high risk of recurrence following surgery met primary endpoint of recurrence-free survivalNew adjuvant treatments are urgently needed as an estimated 70-80% of people with early-stage HCC experience disease recurrence following surgery1Data will be discussed with health authorities globally, including the US Food and Drug Administration and the European Medicines Agency to inform the next regulatory steps, and presented at an upcoming medical meetingBasel, 19 January 2023 - Roche (SIX: RO, ROG;...
Source: Roche Investor Update - January 19, 2023 Category: Pharmaceuticals Source Type: news
[Ad hoc announcement pursuant to Art. 53 LR] Roche ’s Tecentriq plus Avastin is the first treatment combination to reduce the risk of cancer returning in people with certain types of early-stage liver cancer in a Phase III trial
Pivotal Phase III IMbrave050 study investigatingTecentriq plusAvastin in people with early-stage hepatocellular carcinoma (HCC) at high risk of recurrence following surgery met primary endpoint of recurrence-free survivalNew adjuvant treatments are urgently needed as an estimated 70-80% of people with early-stage HCC experience disease recurrence following surgery1Data will be discussed with health authorities globally, including the US Food and Drug Administration and the European Medicines Agency to inform the next regulatory steps, and presented at an upcoming medical meetingBasel, 19 January 2023 - Roche (SIX: RO, ROG;...
Source: Roche Media News - January 19, 2023 Category: Pharmaceuticals Source Type: news
Progress Toward Hepatitis B Control and Elimination of Mother-to-Child Transmission of Hepatitis B Virus - World Health Organization African Region, 2016-2021
This report describes progress towards hepatitis B control and elimination in the World Health Organization African region. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - January 6, 2023 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Source Type: news
Sex Differences in HBV-Associated Liver Cancer Sex Differences in HBV-Associated Liver Cancer
Liver cancer genetics and biology differ between men and women and help explain why aflatoxin exposure increases the risk in hepatitis B virus (HBV) –infected patients, particularly in men.MDedge News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 5, 2023 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Hepatitis B vaccine: What to know to protect yourself
Hepatitis is inflammation in the liver caused by specific viruses. The hepatitis viruses are referred to as types A, B, C, D and E. All types affect the liver, but they differ in illness severity and prevention options. In the U.S., the most common forms are hepatitis A, hepatitis B and hepatitis C. Acute or chronic hepatitis B Hepatitis B is a serious disease caused by a virus that attacks the liver. It's one of the more… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 13, 2022 Category: Databases & Libraries Source Type: news
Emergency department opt out testing for HIV, hepatitis B and hepatitis C: The first 100 days
This report describes the progress, challenges, results and learning of the first 100 days of an initiative to implement opt out testing for HIV, hepatitis B and hepatitis C in emergency departments in the parts of England with the highest diagnosed prevalence of HIV infection. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 5, 2022 Category: Consumer Health News Source Type: news
Bepirovirsen Studied for Treatment of Chronic Hepatitis B Infection
MONDAY, Nov. 14, 2022 -- A 300-mg dose of bepirovirsen per week for 24 weeks results in sustained hepatitis B surface antigen (HBsAg) and hepatitis B virus (HBV) DNA loss in 9 to 10 percent of patients with chronic HBV infection, according to a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 14, 2022 Category: General Medicine Source Type: news
What Are the Potential Benefits and Risks of Premasticated Foods?
Discussion
Premastication is the prechewing of foods or medicines by another person before feeding to an infant. It is also used to pretaste or temperature test foods. It was a common practice for millennia, especially before modern food technology, as a way to transition an infant from a solely liquid based diet to a mixed diet mainly of solid food. Rates of premastication vary, with less developed countries having an increased incidence/prevalence (up to 50%) but it is not uncommon in developed countries (in the US 14% is reported).
Saliva is also used to clean other people, treat cuts/itches or insect bites as well. Pla...
Source: PediatricEducation.org - November 14, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Chronic HBV Infections Associated With Liver Malignancies Chronic HBV Infections Associated With Liver Malignancies
Treatment with nucleos(t)ide analogues lowers risk of extrahepatic cancer in patients with hepatitis B infections.MDedge News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - November 12, 2022 Category: Cancer & Oncology Tags: Gastroenterology News Source Type: news
Novel Hepatitis B Drug Hints at Long-Term 'Functional Cure' for Some in Early Trial
(MedPage Today) -- WASHINGTON -- Investigational antisense RNA-based therapy bepirovirsen sustained clearance of both hepatitis B virus (HBV) DNA and surface antigen (HBsAg) for a modest proportion of patients out to 6 months after injections... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 11, 2022 Category: Gastroenterology Source Type: news
Tenofovir, Vaccine Combo Eliminates Mom-to-Child HBV Transmission
(MedPage Today) -- Earlier maternal tenofovir disoproxil fumarate (TDF) combined with infant vaccination completely eliminated vertical transmission of chronic hepatitis B virus (HBV) from highly viremic mothers, even without the use of hepatitis... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 8, 2022 Category: Gastroenterology Source Type: news
