Nipah virus at 20
This week I attended the Nipah Virus International Conference in Singapore, marking the discovery of the virus 20 years ago. It’s an opportune time to recall the events around the emergence of this deadly pathogen. An outbreak of respiratory disease and encephalitis in pigs during 1998 took place in Ipoh City of Perak state in […] (Source: virology blog)
Source: virology blog - December 12, 2019 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information encephalitis fruit bat Hendra virus henipavirus Nipah virus pandemic Pteropus respiratory disease spillover viral viruses Source Type: blogs

Funtabulously Frivolous Friday Five 209
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 209. Question 1 Who wrote in their journal “I did not sleep at all last night. It hurts like the devil! A snowstorm whipping through my soul, wailing like a hundred jackals. Still no obvious symptoms that perforation is imminent, but an o...
Source: Life in the Fast Lane - October 13, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five Anosmia Antartica appendicitis body packing Boring and Boring cocaine Edwin Boring Freesias ketones Leonid Rogozov Lucy Boring sleep temporal reference toponymous disease Source Type: blogs

Whole issues of Genome Biology/Genome Medicine on "Genomics of Infectious Disease"
Wow this has really got some nice papers: BioMed Central | Article collections | Genomics of infectious diseases special issue.  I note - this goes well as a follow up to the series I co-coordinated in PLOS a few years back: Genomics of Emerging Infectious Disease - PLOS CollectionsFrom their site:Infectious diseases are major contributors to global morbidity and mortality, and have a devastating impact on public health. The World Health Organization estimates that 1 in 3 deaths worldwide are due to an infectious disease, with a disproportionate number occurring in developing regions. While the completi...
Source: The Tree of Life - November 23, 2014 Category: Medical Scientists Authors: Jonathan Eisen Source Type: blogs

Could the Ebola virus epidemic have been prevented?
The cover of this week’s issue of Businessweek declares that ‘Ebola is coming’ in letters colored like blood, with the subtitle ‘The US had a chance to stop the virus in its tracks. It missed’. Although the article presents a good analysis of the hurdles in developing antibody therapy for Ebola virus infection, the cover is overstated. Why does Businessweek think that Ebola virus is coming to the US? (there is no mention of this topic in the article). Are we sure that antibody therapy would have stopped the outbreak? (no, as stated in the article). How the U.S. Screwed Up in the Fight Against ...
Source: virology blog - September 30, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Commentary Information antiviral ebola virus ebolavirus epidemic monoclonal antibody therapy outbreak vaccine West Africa ZMapp Source Type: blogs

Visiting biosafety level-4 laboratories
Experiments with the most dangerous human viruses, such as Ebola virus and Lassa virus, are carried out in biosafety level 4 (BSL-4) laboratories. Since visiting the Northeast Infectious Diseases Laboratory BSL-4 and releasing the documentary video Threading the NEIDL, I was given the opportunity to tour three BSL-4 laboratories in the United States and Australia. My impressions of each facility might be of interest to readers of this blog. Rocky Mountain Laboratories, Hamilton, Montana Rocky Mountain Laboratory (RML) is located in the small and sleepy town of Hamilton, Montana (population 4,508), in the Bitterroot Vally t...
Source: virology blog - July 15, 2014 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information Australian Animal Health Laboratory biosecurity BSL-3 BSL-4 Doherty Institute NEIDL RML Rocky Mountain Laboratory viral virus Source Type: blogs

Influenza A viruses in bats
It is well known that aquatic birds are a major reservoir of influenza A viruses, and that pandemic human influenza virus strains of the past century derive viral genes from this pool. The recent discovery of two new influenza A viruses in bats suggests that this species may constitute another reservoir with even greater genetic diversity. A new influenza virus had previously been isolated from little yellow-shouldered bats (Sturnira lilium) in Guatemala. Three of 316 rectal swabs were positive when tested by a pan-influenza polymerase chain reaction assay. Viral sequences were also detected in liver, intestine, ...
Source: virology blog - November 13, 2013 Category: Virology Authors: Vincent Racaniello Tags: Basic virology Information Artibeus planirostris bat genetic diversity influenza virus pandemic Sturnira lilium viral zoonosis Source Type: blogs

Deadly MERS Virus Discovered in Egyptian Tomb Bat in Saudi Arabia
The deadly Middle East Respiratory Syndrome (MERS) virus has been discovered in an Egyptian Tomb Bat in Saudi Arabia. Experts have been trying to track the source of the mysterious MERS outbreak since it was first discovered in September 2012. 70 of the nearly 100 cases have been in Saudi Arabia. The novel coronavirus has killed 47 people so far. Over a six-week period during field expeditions in October 2012 and April 2013, the researchers collected more than 1,000 samples from seven bat species in regions where cases of MERS were identified. Analysis was performed using polymerase chain reaction and DNA sequencing. One ...
Source: - August 22, 2013 Category: Health Medicine and Bioethics Commentators Tags: bats mers Source Type: blogs