A comprehensive review on the development of sporadic cerebral arteriovenous malformations: from Padget to next-generation sequencing
J Neurosurg. 2024 Mar 22:1-10. doi: 10.3171/2023.12.JNS232233. Online ahead of print.ABSTRACTCerebral arteriovenous malformations (AVMs) are a leading cause of intracerebral hemorrhage in both children and young adults. With the continued advancement of science and technology, the understanding of the pathophysiology behind the development of these lesions has evolved. From early theory published by Harvey Cushing and Percival Bailey in 1928, Tumors Arising from the Blood-vessels of the Brain: Angiomatous Malformations and Hemangioblastoma, which regarded AVMs as tumors arising from blood vessels, to the meticulous artistr...
Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Stephanie A Coffman Keyan Peterson Nicholas Contillo Kyle M Fargen Stacey Q Wolfe Source Type: research
Comprehensive characterization of intracranial hemorrhage in deep brain stimulation: a systematic review of literature from 1987 to 2023
CONCLUSIONS: This study provides level III evidence that MER during DBS is a risk factor for ICH. Other risk factors include intraoperative systolic blood pressure > 140 mm Hg, sulcal trajectories, and multiple microelectrode insertions. Avoidance of these risk factors may decrease the rate of ICH.PMID:38518284 | DOI:10.3171/2024.1.JNS232385 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Cletus Cheyuo Artur Vetkas Can Sarica Suneil K Kalia Mojgan Hodaie Andres M Lozano Source Type: research
A comprehensive review on the development of sporadic cerebral arteriovenous malformations: from Padget to next-generation sequencing
J Neurosurg. 2024 Mar 22:1-10. doi: 10.3171/2023.12.JNS232233. Online ahead of print.ABSTRACTCerebral arteriovenous malformations (AVMs) are a leading cause of intracerebral hemorrhage in both children and young adults. With the continued advancement of science and technology, the understanding of the pathophysiology behind the development of these lesions has evolved. From early theory published by Harvey Cushing and Percival Bailey in 1928, Tumors Arising from the Blood-vessels of the Brain: Angiomatous Malformations and Hemangioblastoma, which regarded AVMs as tumors arising from blood vessels, to the meticulous artistr...
Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Stephanie A Coffman Keyan Peterson Nicholas Contillo Kyle M Fargen Stacey Q Wolfe Source Type: research
Comprehensive characterization of intracranial hemorrhage in deep brain stimulation: a systematic review of literature from 1987 to 2023
CONCLUSIONS: This study provides level III evidence that MER during DBS is a risk factor for ICH. Other risk factors include intraoperative systolic blood pressure > 140 mm Hg, sulcal trajectories, and multiple microelectrode insertions. Avoidance of these risk factors may decrease the rate of ICH.PMID:38518284 | DOI:10.3171/2024.1.JNS232385 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Cletus Cheyuo Artur Vetkas Can Sarica Suneil K Kalia Mojgan Hodaie Andres M Lozano Source Type: research
A comprehensive review on the development of sporadic cerebral arteriovenous malformations: from Padget to next-generation sequencing
J Neurosurg. 2024 Mar 22:1-10. doi: 10.3171/2023.12.JNS232233. Online ahead of print.ABSTRACTCerebral arteriovenous malformations (AVMs) are a leading cause of intracerebral hemorrhage in both children and young adults. With the continued advancement of science and technology, the understanding of the pathophysiology behind the development of these lesions has evolved. From early theory published by Harvey Cushing and Percival Bailey in 1928, Tumors Arising from the Blood-vessels of the Brain: Angiomatous Malformations and Hemangioblastoma, which regarded AVMs as tumors arising from blood vessels, to the meticulous artistr...
Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Stephanie A Coffman Keyan Peterson Nicholas Contillo Kyle M Fargen Stacey Q Wolfe Source Type: research
Comprehensive characterization of intracranial hemorrhage in deep brain stimulation: a systematic review of literature from 1987 to 2023
CONCLUSIONS: This study provides level III evidence that MER during DBS is a risk factor for ICH. Other risk factors include intraoperative systolic blood pressure > 140 mm Hg, sulcal trajectories, and multiple microelectrode insertions. Avoidance of these risk factors may decrease the rate of ICH.PMID:38518284 | DOI:10.3171/2024.1.JNS232385 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Cletus Cheyuo Artur Vetkas Can Sarica Suneil K Kalia Mojgan Hodaie Andres M Lozano Source Type: research
A comprehensive review on the development of sporadic cerebral arteriovenous malformations: from Padget to next-generation sequencing
J Neurosurg. 2024 Mar 22:1-10. doi: 10.3171/2023.12.JNS232233. Online ahead of print.ABSTRACTCerebral arteriovenous malformations (AVMs) are a leading cause of intracerebral hemorrhage in both children and young adults. With the continued advancement of science and technology, the understanding of the pathophysiology behind the development of these lesions has evolved. From early theory published by Harvey Cushing and Percival Bailey in 1928, Tumors Arising from the Blood-vessels of the Brain: Angiomatous Malformations and Hemangioblastoma, which regarded AVMs as tumors arising from blood vessels, to the meticulous artistr...
Source: Journal of Neurosurgery - March 22, 2024 Category: Neurosurgery Authors: Stephanie A Coffman Keyan Peterson Nicholas Contillo Kyle M Fargen Stacey Q Wolfe Source Type: research
A novel nomogram to predict futile recanalization in patients with acute ischemic stroke undergoing mechanical thrombectomy
ConclusionThe nomogram composed of age, SBP, OTR, and 24 h ICH can effectively predict the probability of FR after MT in AIS patients. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research
Pathogenicity of Streptococcus iniae causing mass mortalities of yellow catfish (Tachysurus fulvidraco) and its induced host immune response
The outbreak of mass mortality occurred in Tachysurus fulvidraco farm in Hubei province of China. The pathogenic strain of Streptococcus iniae (termed 2022SI08) was isolated and identified from diseased T. fulvidraco, based on morphological, physiological, and biochemical characteristics, as well as 16S rRNA gene sequence and phylogenetic analysis. Further, the whole genome of isolate S. iniae was sequenced and predicted to contain one single circular chromosome of 1,776,777 bp with a GC content of 37.14%. The genomic sequence analysis showed that 2022SI08 was positive for 204 virulent and 127 antibiotic resistant genes....
Source: Frontiers in Microbiology - March 22, 2024 Category: Microbiology Source Type: research
Impact of healthcare-associated infections within 7-days of acute stroke on health outcomes and risk of care-dependency: a multi-centre registry-based cohort study
AbstractHealthcare-associated infections (HCAIs) in patients admitted with acute conditions remain a major challenge to healthcare services. Here, we assessed the impact of HCAIs acquired within 7-days of acute stroke on indicators of care-quality outcomes and dependency. Data were prospectively collected (2014 –2016) from the Sentinel Stroke National Audit Programme for 3309 patients (mean age = 76.2 yr, SD = 13.5) admitted to four UK hyperacute stroke units (HASU). Associations between variables were assessed by multivariable logistic regression (odds ratios, 95% confidence intervals), adjuste d for age, sex, ...
Source: Internal and Emergency Medicine - March 22, 2024 Category: Emergency Medicine Source Type: research
The ratio of the maximum density values: a new method for predicting hemorrhagic transformation in acute ischemic stroke patients undergoing mechanical thrombectomy
ConclusionThe utilization of RMDV >1 on immediate NCCT scans after MT can predict early HT with good sensitivity and specificity. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 22, 2024 Category: Neurology Source Type: research
Impact of healthcare-associated infections within 7-days of acute stroke on health outcomes and risk of care-dependency: a multi-centre registry-based cohort study
AbstractHealthcare-associated infections (HCAIs) in patients admitted with acute conditions remain a major challenge to healthcare services. Here, we assessed the impact of HCAIs acquired within 7-days of acute stroke on indicators of care-quality outcomes and dependency. Data were prospectively collected (2014 –2016) from the Sentinel Stroke National Audit Programme for 3309 patients (mean age = 76.2 yr, SD = 13.5) admitted to four UK hyperacute stroke units (HASU). Associations between variables were assessed by multivariable logistic regression (odds ratios, 95% confidence intervals), adjuste d for age, sex, ...
Source: Internal and Emergency Medicine - March 22, 2024 Category: Emergency Medicine Source Type: research
Revolutionizing brain interventions: the multifaceted potential of histotripsy
In conclusion, histotripsy offers diverse potential in the field of brain interventions, encompassing applications ranging from tumor treatment to the management of intracerebral hemorrhage. While challenges such as accurate monitoring and differentiation of treatme nt effects persist, ongoing research efforts and technological advancements continue to expand the role of histotripsy in both neurology and neurosurgery. (Source: Neurosurgical Review)
Source: Neurosurgical Review - March 21, 2024 Category: Neurosurgery Source Type: research
Higher risk of traumatic intracranial hemorrhage with antiplatelet therapy compared to oral anticoagulation —a single-center experience
ConclusionThis study shows that antiplatelet therapy is associated with a higher risk of traumatic intracranial hemorrhage compared to oral anticoagulation. Antiplatelet therapy should be given equal or greater consideration in the guidelines compared to anticoagulation therapy. Further studies on antiplatelet subtypes within the context of head trauma are recommended to improve the guidelines ’ diagnostic accuracy. (Source: European Journal of Trauma and Emergency Surgery)
Source: European Journal of Trauma and Emergency Surgery - March 21, 2024 Category: Emergency Medicine Source Type: research
De Novo Brain Vascular Malformations in Hereditary Hemorrhagic Telangiectasia
Approximately 10% of people with hereditary hemorrhagic telangiectasia (HHT) have brain vascular malformations (VMs). Few reports describe de novo brain VM formation or VM growth. International HHT Guidelines recommend initial brain VM screening upon HHT diagnosis in children but do not address rescreening. We aimed to confirm whether brain VMs can form de novo in patients with HHT. (Source: Pediatric Neurology)
Source: Pediatric Neurology - March 21, 2024 Category: Neurology Authors: Lauren A. Beslow, Timo Krings, Helen Kim, Steven W. Hetts, Michael T. Lawton, Felix Ratjen, Kevin J. Whitehead, James R. Gossage, Charles E. McCulloch, Marianne Clancy, Negar Bagheri, Marie E. Faughnan, the Brain Vascular Malformation Consortium HHT Inves Tags: Research Paper Source Type: research
