Neuroprotective effects of VCE-004.8 in a rat model of neonatal stroke
CONCLUSIONS: These data suggest that this drug could be effective for the treatment of stroke in newborns.PMID:38582276 | DOI:10.1016/j.ejphar.2024.176554 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - April 6, 2024 Category: Drugs & Pharmacology Authors: Mar ía Villa Mar ía Martínez-Vega Laura Silva Angela Romero Mar ía de Hoz-Rivera Mar ía Eugenia Prados Eduardo Mu ñoz Jos é Martínez-Orgado Source Type: research

Neuroprotective effects of VCE-004.8 in a rat model of neonatal stroke
CONCLUSIONS: These data suggest that this drug could be effective for the treatment of stroke in newborns.PMID:38582276 | DOI:10.1016/j.ejphar.2024.176554 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - April 6, 2024 Category: Drugs & Pharmacology Authors: Mar ía Villa Mar ía Martínez-Vega Laura Silva Angela Romero Mar ía de Hoz-Rivera Mar ía Eugenia Prados Eduardo Mu ñoz Jos é Martínez-Orgado Source Type: research

Keeping prior anticoagulation treatment in the acute phase of ischaemic stroke: the REKOALA study
ConclusionContinuation of anticoagulation in patients with acute ischaemic stroke and cardioembolic source did not increase the risk of intracranial haemorrhage and may be associated with better functional outcomes. (Source: Journal of Neurology)
Source: Journal of Neurology - April 5, 2024 Category: Neurology Source Type: research

Ticagrelor versus clopidogrel in dual antiplatelet therapy after minor stroke or transient ischemic attack: an updated network meta-analysis
ConclusionsDAPTs were superior to aspirin in preventing recurrence or ischemic stroke. Although no significant difference was observed between DAPTs, ticagrelor plus aspirin may be related to worse major bleeding results, including intracranial bleeding. Ticagrelor plus aspirin is a considerable option for patients after a minor stroke or TIA. (Source: Journal of Neurology)
Source: Journal of Neurology - April 5, 2024 Category: Neurology Source Type: research

Hypertensive Disorders of Pregnancy
Am Fam Physician. 2024 Mar;109(3):251-260.ABSTRACTHypertensive disorders of pregnancy are a major contributor to maternal morbidity and mortality in the United States and include chronic and gestational hypertension, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome, eclampsia, and chronic hypertension with superimposed preeclampsia. For patients with chronic hypertension, oral antihypertensive therapy should be initiated or titrated at a blood pressure threshold of 140/90 mm Hg or greater. Gestational hypertension and preeclampsia without severe features can be managed with blood pre...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Narges Farahi Fareedat Oluyadi Andrea B Dotson Source Type: research

Hypertensive Disorders of Pregnancy
Am Fam Physician. 2024 Mar;109(3):251-260.ABSTRACTHypertensive disorders of pregnancy are a major contributor to maternal morbidity and mortality in the United States and include chronic and gestational hypertension, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome, eclampsia, and chronic hypertension with superimposed preeclampsia. For patients with chronic hypertension, oral antihypertensive therapy should be initiated or titrated at a blood pressure threshold of 140/90 mm Hg or greater. Gestational hypertension and preeclampsia without severe features can be managed with blood pre...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Narges Farahi Fareedat Oluyadi Andrea B Dotson Source Type: research

Hypertensive Disorders of Pregnancy
Am Fam Physician. 2024 Mar;109(3):251-260.ABSTRACTHypertensive disorders of pregnancy are a major contributor to maternal morbidity and mortality in the United States and include chronic and gestational hypertension, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome, eclampsia, and chronic hypertension with superimposed preeclampsia. For patients with chronic hypertension, oral antihypertensive therapy should be initiated or titrated at a blood pressure threshold of 140/90 mm Hg or greater. Gestational hypertension and preeclampsia without severe features can be managed with blood pre...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Narges Farahi Fareedat Oluyadi Andrea B Dotson Source Type: research

Hypertensive Disorders of Pregnancy
Am Fam Physician. 2024 Mar;109(3):251-260.ABSTRACTHypertensive disorders of pregnancy are a major contributor to maternal morbidity and mortality in the United States and include chronic and gestational hypertension, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome, eclampsia, and chronic hypertension with superimposed preeclampsia. For patients with chronic hypertension, oral antihypertensive therapy should be initiated or titrated at a blood pressure threshold of 140/90 mm Hg or greater. Gestational hypertension and preeclampsia without severe features can be managed with blood pre...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Narges Farahi Fareedat Oluyadi Andrea B Dotson Source Type: research

Hypertensive Disorders of Pregnancy
Am Fam Physician. 2024 Mar;109(3):251-260.ABSTRACTHypertensive disorders of pregnancy are a major contributor to maternal morbidity and mortality in the United States and include chronic and gestational hypertension, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome, eclampsia, and chronic hypertension with superimposed preeclampsia. For patients with chronic hypertension, oral antihypertensive therapy should be initiated or titrated at a blood pressure threshold of 140/90 mm Hg or greater. Gestational hypertension and preeclampsia without severe features can be managed with blood pre...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Narges Farahi Fareedat Oluyadi Andrea B Dotson Source Type: research

Hypertensive Disorders of Pregnancy
Am Fam Physician. 2024 Mar;109(3):251-260.ABSTRACTHypertensive disorders of pregnancy are a major contributor to maternal morbidity and mortality in the United States and include chronic and gestational hypertension, preeclampsia, HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome, eclampsia, and chronic hypertension with superimposed preeclampsia. For patients with chronic hypertension, oral antihypertensive therapy should be initiated or titrated at a blood pressure threshold of 140/90 mm Hg or greater. Gestational hypertension and preeclampsia without severe features can be managed with blood pre...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Narges Farahi Fareedat Oluyadi Andrea B Dotson Source Type: research