Shifting Paradigms and Arising Concerns in Severe Hemophilia A Treatment
Semin Thromb Hemost DOI: 10.1055/s-0043-1778103The management of hemophilia A has undergone a remarkable revolution, in line with technological advancement. In the recent past, the primary concern associated with Factor VIII (FVIII) concentrates was the risk of infections, which is now almost resolved by advanced blood screening and viral inactivation methods. Improving patients' compliance with prophylaxis has become a key focus, as it can lead to improved health outcomes and reduced health care costs in the long term. Recent bioengineering research is directed toward prolonging the recombinant FVIII (rFVIII) coagulant ac...
Source: Seminars in Thrombosis and Hemostasis - January 15, 2024 Category: Hematology Authors: Chandran, Rubhan Tohit, Eusni R. Mohd. Stanslas, Johnson Salim, Norazlinaliza Mahmood, Tuan M.T. Rajagopal, Mogana Tags: Review Article Source Type: research
Adult People with Hemophilia A Have Low Annualized Bleeding Rate, However the Arthropathy Remains a Burden: A Retrospective Cohort Study
AbstractCongenital Hemophilia A is a complex disease to treat, especially in places without access to hemophilia treatment centers (HTCs). The primary aim of this study was to analyze the outcomes of a cohort of adult people with congenital hemophilia A in an HTC localized in the Bajio region of Mexico. Observational retrospective study of a cohort of 82 adult people with congenital hemophilia A treated in a tertiary-level hospital in the Bajio region of Mexico, between June 2022 and June 2023. The median age of the patients was 29.5 years, 60.9% with severe hemophilia A, 53.6% were under some factor VIII prophylaxis reg...
Source: Indian Journal of Hematology and Blood Transfusion - January 15, 2024 Category: Hematology Source Type: research
Spontaneous intramural hematoma of the small bowel in a hemophilia A patient
(Source: Internal and Emergency Medicine)
Source: Internal and Emergency Medicine - January 13, 2024 Category: Emergency Medicine Source Type: research
