Immunoglobulin G-mediated food intolerance and metabolic syndrome influence the occurrence of reflux esophagitis in < em > Helicobacter pylori < /em > -infected patients
CONCLUSION: Patients with IgG-mediated food intolerance and metabolic syndrome were at higher risk of developing reflux esophagitis, while patients with H. pylori infection were at lower risk. IgG-mediated food intolerance reduced the risk of reflux esophagitis pathogenesis in patients with H. pylori infection; however, metabolic syndrome increased the risk of patients with H. pylori infection developing reflux esophagitis.PMID:38516244 | PMC:PMC10950645 | DOI:10.3748/wjg.v30.i8.855 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Li-Hui Wang Bin-Bin Su Sheng-Shu Wang Guan-Chao Sun Kun-Ming Lv Yi Li Hui Shi Qian-Qian Chen Source Type: research
Bibliometrics analysis based on the Web of Science: Current trends and perspective of gastric organoid during 2010-2023
CONCLUSION: Key focus areas of research using gastric organoids include unraveling disease mechanisms and enhancing drug screening techniques. Major contributions from renowned academic institutions highlight this field's dynamic growth.PMID:38516239 | PMC:PMC10950634 | DOI:10.3748/wjg.v30.i8.969 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Kai-Lin Jiang Yue-Bo Jia Xue-Jiao Liu Qing-Ling Jia Li-Kun Guo Xiang-Xiang Wang Ke-Ming Yang Chen-Heng Wu Bei-Bei Liang Jiang-Hong Ling Source Type: research
Immunoglobulin G-mediated food intolerance and metabolic syndrome influence the occurrence of reflux esophagitis in < em > Helicobacter pylori < /em > -infected patients
CONCLUSION: Patients with IgG-mediated food intolerance and metabolic syndrome were at higher risk of developing reflux esophagitis, while patients with H. pylori infection were at lower risk. IgG-mediated food intolerance reduced the risk of reflux esophagitis pathogenesis in patients with H. pylori infection; however, metabolic syndrome increased the risk of patients with H. pylori infection developing reflux esophagitis.PMID:38516244 | PMC:PMC10950645 | DOI:10.3748/wjg.v30.i8.855 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Li-Hui Wang Bin-Bin Su Sheng-Shu Wang Guan-Chao Sun Kun-Ming Lv Yi Li Hui Shi Qian-Qian Chen Source Type: research
Bibliometrics analysis based on the Web of Science: Current trends and perspective of gastric organoid during 2010-2023
CONCLUSION: Key focus areas of research using gastric organoids include unraveling disease mechanisms and enhancing drug screening techniques. Major contributions from renowned academic institutions highlight this field's dynamic growth.PMID:38516239 | PMC:PMC10950634 | DOI:10.3748/wjg.v30.i8.969 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Kai-Lin Jiang Yue-Bo Jia Xue-Jiao Liu Qing-Ling Jia Li-Kun Guo Xiang-Xiang Wang Ke-Ming Yang Chen-Heng Wu Bei-Bei Liang Jiang-Hong Ling Source Type: research
Chinese National Clinical Practice Guidelines on the Prevention, Diagnosis, and Treatment of Early Gastric Cancer
CONCLUSIONS: This CPG can lead to optimum care for patients and populations by providing up-to-date medical information. We intend this CPG for widespread adoption to increase the standard of prevention, screening, diagnosis, treatment, and follow-up of early gastric cancer; thereby, contributing to improving national health care and patient quality of life.PMID:38515297 | DOI:10.1097/CM9.0000000000003101 (Source: Chinese Medical Journal)
Source: Chinese Medical Journal - March 22, 2024 Category: General Medicine Authors: Society of Digestive Endoscopy of the Chinese Medical Association, Colorectal Surgery Group of the Chinese Medical Association, Chinese Association of Gastroenterologists & Hepatologists, National Clinical Research Center for Digestive Diseases, Workshop Source Type: research
Clinicopathological and endoscopic features of Helicobacter pylori infection-negative gastric cancer in Japan: a retrospective study
CONCLUSIONS: This study revealed that tumors from each gastric region exhibited distinct macroscopic and histological types in HPNGC.PMID:38514987 | DOI:10.5946/ce.2023.258 (Source: Clinical Endoscopy)
Source: Clinical Endoscopy - March 22, 2024 Category: Gastroenterology Authors: Kentaro Imamura Kenshi Yao Satoshi Nimura Takao Kanemitsu Masaki Miyaoka Yoichiro Ono Toshiharu Ueki Hiroshi Tanabe Source Type: research
Novel carbonic anhydrase inhibitors for the treatment of < em > Helicobacter pylori < /em > infection
Expert Opin Investig Drugs. 2024 Mar 22. doi: 10.1080/13543784.2024.2334714. Online ahead of print.ABSTRACTINTRODUCTION: Helicobacter pylori, the causative agent of peptic ulcer, gastritis and gastric cancer encodes two carbonic anhydrases (CA, EC 4.2.1.1) belonging to the α- and β-class (HpCAα/β), which have been validated as antibacterial drug targets. Acetazolamide and ethoxzolamide were also clinically used for the management of peptic ulcer.AREAS COVERED: Sulfonamides were the most investigated HpCAα/β compounds, with several low nanomolar inhibitors indentified, some of which also crystallized as adducts with H...
Source: Expert Opinion on Investigational Drugs - March 22, 2024 Category: Drugs & Pharmacology Authors: Claudiu T Supuran Source Type: research
