Systematic Review and Meta-analysis of Tongxinluo Capsule Therapy for Acute Myocardial Infarction
CONCLUSIONS: The meta-analysis showed that the TXL capsule can bring greater therapeutic benefits for AMI patients in combination with routine treatment. The current study was a meta-analysis, and the field needs more well-designed studies.PMID:38581311 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Yukai Zhao Dongmei Wan Qian Xu Wenji Zhai Jing Gao Yujia Zhang Limei Deng Source Type: research

Systematic Review and Meta-analysis of Tongxinluo Capsule Therapy for Acute Myocardial Infarction
CONCLUSIONS: The meta-analysis showed that the TXL capsule can bring greater therapeutic benefits for AMI patients in combination with routine treatment. The current study was a meta-analysis, and the field needs more well-designed studies.PMID:38581311 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Yukai Zhao Dongmei Wan Qian Xu Wenji Zhai Jing Gao Yujia Zhang Limei Deng Source Type: research

Systematic Review and Meta-analysis of Tongxinluo Capsule Therapy for Acute Myocardial Infarction
CONCLUSIONS: The meta-analysis showed that the TXL capsule can bring greater therapeutic benefits for AMI patients in combination with routine treatment. The current study was a meta-analysis, and the field needs more well-designed studies.PMID:38581311 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Yukai Zhao Dongmei Wan Qian Xu Wenji Zhai Jing Gao Yujia Zhang Limei Deng Source Type: research

Clopidogrel induced reduction in neutrophil count: An overlooked beneficial effect?
Eur J Intern Med. 2024 Apr 5:S0953-6205(24)00135-3. doi: 10.1016/j.ejim.2024.03.026. Online ahead of print.ABSTRACTComplement-stimulated neutrophils are able to adhere to the endothelium and damage endothelial cells both in vitro and in vivo. These blood cells participate in the early stages, growth and complications of atherosclerotic plaques. Recent findings, based on mendelian randomization analysis, support the concept that high neutrophil counts are a causal risk factor for ischemic heart disease and myocardial infarction . Clopidogrel decreases leukocyte count and inflammatory markers in patients with acute coronary ...
Source: European Journal of Internal Medicine - April 6, 2024 Category: Internal Medicine Authors: Stefano De Servi Antonio Landi Stefano Savonitto Source Type: research

Surface plasmon resonance biosensors for early troponin detection
Clin Chim Acta. 2024 Apr 4:118670. doi: 10.1016/j.cca.2024.118670. Online ahead of print.ABSTRACTAcute myocardial infarction (AMI) is one of the life-threatening causes that decrease blood flow to the heart, leading to increased mortality and related complications. Recently, the measure of blood concentration of cardiac biomarkers has been suggested to overcome the limitations of electrocardiography (ECG) analyses for early diagnosis of this disease. Troponins, especially cardiac troponin I and cardiac troponin T, with high sensitivity and specificity, are considered the gold standards in myocardial diagnosis. Recently, th...
Source: International Journal of Clinical Chemistry - April 6, 2024 Category: Chemistry Authors: Faride Ranjbari Ali Nosrat Farzaneh Fathi Alireza Mohammadzadeh Source Type: research

Unawareness of being prescribed medications for diabetes and incident cardiovascular disease
CONCLUSIONS: In patients with diabetes taking medications for diabetes, even if they are young and have good glycemic control, it is important that they receive adequate education from their healthcare providers to accurately identify their treatment status.PMID:38582492 | DOI:10.1016/j.jjcc.2024.03.011 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 6, 2024 Category: Cardiology Authors: Jin Komuro Hidehiro Kaneko Yuta Suzuki Akira Okada Kaoruko Komuro Atsushi Mizuno Katsuhito Fujiu Taisuke Jo Norifumi Takeda Hiroyuki Morita Koichi Node Hideo Yasunaga Masaki Ieda Issei Komuro Source Type: research

Heparanase promotes the onset and progression of atherosclerosis in apolipoprotein E gene knockout mice
CONCLUSIONS: This study identifies Hpse as a key pro-inflammatory enzyme driving the initiation and progression of atherosclerosis and highlighting the potential of Hpse inhibitors as novel anti-inflammatory treatments for cardiovascular disease.PMID:38581737 | DOI:10.1016/j.atherosclerosis.2024.117519 (Source: Atherosclerosis)
Source: Atherosclerosis - April 6, 2024 Category: Cardiology Authors: Tien K Nguyen Stephanie Paone Amy A Baxter Alyce J Mayfosh Thanh Kha Phan Enoch Chan Karlheinz Peter Ivan K H Poon Shane R Thomas Mark D Hulett Source Type: research

Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights from the EMPACT-MI Trial
CONCLUSIONS: In patients after acute myocardial infarction with left ventricular dysfunction or congestion, empagliflozin reduced the risk of heart failure.PMID:38581389 | DOI:10.1161/CIRCULATIONAHA.124.069217 (Source: Circulation)
Source: Circulation - April 6, 2024 Category: Cardiology Authors: Adrian F Hernandez Jacob A Udell W Schuyler Jones Stefan D Anker Mark C Petrie Josephine Harrington Michaela Mattheus Svenja Seide Isabella Zwiener Offer Amir M Cecilia Bahit Johann Bauersachs Antoni Bayes-Genis Yundai Chen Vijay K Chopra Gemma Figtree Ju Source Type: research

Systematic Review and Meta-analysis of Tongxinluo Capsule Therapy for Acute Myocardial Infarction
CONCLUSIONS: The meta-analysis showed that the TXL capsule can bring greater therapeutic benefits for AMI patients in combination with routine treatment. The current study was a meta-analysis, and the field needs more well-designed studies.PMID:38581311 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Yukai Zhao Dongmei Wan Qian Xu Wenji Zhai Jing Gao Yujia Zhang Limei Deng Source Type: research

Surface plasmon resonance biosensors for early troponin detection
Clin Chim Acta. 2024 Apr 4:118670. doi: 10.1016/j.cca.2024.118670. Online ahead of print.ABSTRACTAcute myocardial infarction (AMI) is one of the life-threatening causes that decrease blood flow to the heart, leading to increased mortality and related complications. Recently, the measure of blood concentration of cardiac biomarkers has been suggested to overcome the limitations of electrocardiography (ECG) analyses for early diagnosis of this disease. Troponins, especially cardiac troponin I and cardiac troponin T, with high sensitivity and specificity, are considered the gold standards in myocardial diagnosis. Recently, th...
Source: International Journal of Clinical Chemistry - April 6, 2024 Category: Chemistry Authors: Faride Ranjbari Ali Nosrat Farzaneh Fathi Alireza Mohammadzadeh Source Type: research

Clopidogrel induced reduction in neutrophil count: An overlooked beneficial effect?
Eur J Intern Med. 2024 Apr 5:S0953-6205(24)00135-3. doi: 10.1016/j.ejim.2024.03.026. Online ahead of print.ABSTRACTComplement-stimulated neutrophils are able to adhere to the endothelium and damage endothelial cells both in vitro and in vivo. These blood cells participate in the early stages, growth and complications of atherosclerotic plaques. Recent findings, based on mendelian randomization analysis, support the concept that high neutrophil counts are a causal risk factor for ischemic heart disease and myocardial infarction . Clopidogrel decreases leukocyte count and inflammatory markers in patients with acute coronary ...
Source: European Journal of Internal Medicine - April 6, 2024 Category: Internal Medicine Authors: Stefano De Servi Antonio Landi Stefano Savonitto Source Type: research

Effect of Empagliflozin on Heart Failure Outcomes After Acute Myocardial Infarction: Insights from the EMPACT-MI Trial
CONCLUSIONS: In patients after acute myocardial infarction with left ventricular dysfunction or congestion, empagliflozin reduced the risk of heart failure.PMID:38581389 | DOI:10.1161/CIRCULATIONAHA.124.069217 (Source: Circulation)
Source: Circulation - April 6, 2024 Category: Cardiology Authors: Adrian F Hernandez Jacob A Udell W Schuyler Jones Stefan D Anker Mark C Petrie Josephine Harrington Michaela Mattheus Svenja Seide Isabella Zwiener Offer Amir M Cecilia Bahit Johann Bauersachs Antoni Bayes-Genis Yundai Chen Vijay K Chopra Gemma Figtree Ju Source Type: research

Systematic Review and Meta-analysis of Tongxinluo Capsule Therapy for Acute Myocardial Infarction
CONCLUSIONS: The meta-analysis showed that the TXL capsule can bring greater therapeutic benefits for AMI patients in combination with routine treatment. The current study was a meta-analysis, and the field needs more well-designed studies.PMID:38581311 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 6, 2024 Category: Complementary Medicine Authors: Yukai Zhao Dongmei Wan Qian Xu Wenji Zhai Jing Gao Yujia Zhang Limei Deng Source Type: research

Reply to: Kavsak et al. The clinical chemistry score (CCS) achieves the highest efficacy when assessed with the 99% sensitivity benchmark for myocardial infarction
ESC Guidelines recommend rule-out strategies, that provide an optimal balance between clinical safety and efficacy. In our study, MACE rates (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 6, 2024 Category: Cardiology Authors: Mustafa Yildirim, Evangelos Giannitsis, Matthias Mueller-Hennessen Source Type: research

Sex and racial disparities in non-alcoholic fatty liver disease-related cardiovascular events: National inpatient sample analysis (2019)
CONCLUSION: Increasing age and male sex link NAFLD with adverse MACCE outcomes; Native Americans and Asian Pacific Islanders face higher mortality, highlighting a need for tailored interventions and care.PMID:38576521 | PMC:PMC10989223 | DOI:10.4330/wjc.v16.i3.137 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - April 5, 2024 Category: Cardiology Authors: Rupak Desai Ali Tariq Alvi Advait Vasavada Yashwitha Sai Pulakurthi Bhavin Patel Adil Sarvar Mohammed Shreyans Doshi Ikechukwu Ogbu Source Type: research