Inflammation REduction to Prevent cArdiovascular Injury in Renal Disease (REPAIR)
Conditions: Chronic Kidney Diseases; Renal Failure Interventions: Drug: Colchicine Sponsors: Hamilton Health Sciences Corporation; Hamilton Academic Health Sciences Organization; St. Joseph ' s Health Care London Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials
Prophylactic Radiotherapy Of MInimally Symptomatic Spinal Disease (PROMISSeD): study protocol for a randomized controlled trial
DiscussionThe results of this RCT will demonstrate the value, if any, of early radiotherapy for high-risk spine metastases. The trial has received IRB approval, funding, and prospective registration (NCT05534321) and has been open to accrual since August 19, 2022. If positive, the trial will expand the scope and utility of spine radiotherapy.Trial registrationClinicalTrials.GovNCT05534321. Registered September 9, 2022.Trial statusVersion 2.0 of the protocol (2021-KOT-002), revised last on September 2, 2022, was approved by the WCG institutional review board (Study Number 1337188, IRB tracking number 20223735). The trial wa...
Source: Trials - January 12, 2024 Category: Research Source Type: clinical trials
Prognostic Value of Conization and Negative HPV After Conization in AIS and Early Stage Cervical Cancer
Conditions: Cervix Cancer; HPV-Related Malignancy Sponsors: Rambam Health Care Campus Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2024 Category: Research Source Type: clinical trials
Protocol of a monocentric, double-blind, randomized, superiority, controlled trial evaluating the effect of in-prison OROS-methylphenidate vs. placebo treatment in detained people with attention-deficit hyperactivity disorder (BATIR)
This study is a phase III, double-blinded, randomized, superiority, controlled trial of OROS-MPHvs. placebo. After randomization, the participants will receive 3 months of treatment with OROS-MPH or placebo (1:1 ratio) while incarcerated. Upon release, all participants will be offered the treatment (OROS-MPH) for 1 year but will remain blinded to their initial study group. The study will be conducted at the Division of Prison Health, Geneva, Switzerland, among incarcerated men (n = 150). Measures will include (1) investigator-rated ADHD symptoms, (2) acute events collected by the medical and prison teams, (3) assessment of...
Source: Trials - January 4, 2024 Category: Research Source Type: clinical trials
Effects of COVID-19 Infection on Pregnancy Outcomes and Offspring Health
Conditions: COVID-19 Interventions: Other: No intervention Sponsors: Shandong University; The Second Affiliated Hospital of Shandong University of traditional Chinese Medicine; The Second Hospital of Shandong University; The Affiliated Hospital of Qingdao University; Yantai Yuhuangding Hospital Affiliated to Qingdao University; Yantai City Yantai Mountain Hospital; the First People ' s Hospital of Jining; Weifang People ' s Hospital; Affiliated hospital of jining medical college; Linyi People ' s Hospital; Dezhou People ' s Hospital; The Affiliated Hospital of Binzhou Medical College; Liaocheng People ' s Hospital; The Sec...
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials
Universal Basic Income and Structural Racism in the US South: HIV Care
Conditions: HIV; Health Care Utilization Interventions: Behavioral: Universal Basic Income Sponsors: University of Arkansas Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 29, 2023 Category: Research Source Type: clinical trials
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
Conditions: Surgery; Aging; Health Care Utilization; Frailty Interventions: Other: Process Mapping: Observations; Other: Process Mapping: Interviews; Other: Process Mapping: Focus Group; Other: Participatory Design Sponsors: University of Wisconsin, Madison; National Institute on Aging (NIA) Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 29, 2023 Category: Research Source Type: clinical trials
Implementing the Transcultural Social-Ethical-Care Model -TEC-MED for Older People in the Mediterranean Basin
Conditions: Older People; Care Dependency; Social Exclusion Interventions: Other: Socio-health care Sponsors: REGINA ALLANDE CUSSO Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials
Time of Oxytocin Initiation at 2nd Stage of Labor and Adverse Outcomes
Conditions: Delivery Complication; Cesarean Delivery Affecting Fetus Interventions: Drug: Oxytocin Sponsors: Rambam Health Care Campus Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 25, 2023 Category: Research Source Type: clinical trials
An Open Label Extension Study of Monepantel in Individuals With Motor Neurone Disease
Conditions: Motor Neuron Disease Interventions: Drug: Monepantel Sponsors: PharmAust Ltd; Calvary Health Care Bethlehem; Macquarie University, Australia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 20, 2023 Category: Research Source Type: clinical trials
ASPIRE: Adapting Self-Blood Pressure Monitoring to Reduce Health Disparities
Conditions: Hypertension Interventions: Behavioral: ASPIRE Intervention Sponsors: Advocate Health Care Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 19, 2023 Category: Research Source Type: clinical trials
Introduction of Preconception Care Through Public Health System for Improving MNCH & FP
Conditions: Feasibility; Acceptability of Health Care Interventions: Behavioral: Preconception care (PCC) Sponsors: International Centre for Diarrhoeal Disease Research, Bangladesh; Directorate General of Family Planning, Minstry of Health and Family Welfare, Bangladesh; Directorate General of Health Services, Minstry of Health and Family Welfare, Bangladesh; UNFPA; FCDO Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 19, 2023 Category: Research Source Type: clinical trials
Understanding context of violence against healthcare through citizen science and evaluating the effectiveness of a co-designed code of conduct and of a tailored de-escalation of violence training in Eastern Democratic Republic of Congo and Iraq: a study protocol for a stepped wedge randomized controlled trial
This study aims therefore to compare the effectiveness and cost-effectiveness of different interventions to reduce violence against HCWs in two post-crisis settings, providing valuable evidence for future efforts to address this issue.Trial registrationClinicalTrial.gov Identifier NCT05419687. Prospectively registered on June 15, 2022. (Source: Trials)
Source: Trials - December 19, 2023 Category: Research Source Type: clinical trials
Direct letters to relatives at risk of hereditary cancer —study protocol for a multi-center randomized controlled trial of healthcare-assisted versus family-mediated risk disclosure at Swedish cancer genetics clinics (DIRECT-study)
In this study, we evaluate healthcare-assisted direct letters to relatives at risk of hereditary cancer syndromes in a randomized controlled trial.MethodsProbands are recruited from Swedish outpatient cancer genetics clinics to this two-arm randomized controlled trial. The study recruits probands with either a pathogenic variant in a cancer susceptibility gene (BRCA1,BRCA2,PALB2,MLH1,MSH2,MSH6,PMS2) or probands with familial breast and colorectal cancer based on clinical and pedigree criteria. In both arms, probands receive standard care, i.e., are encouraged and supported to pass on information to relatives. In the interv...
Source: Trials - December 17, 2023 Category: Research Source Type: clinical trials
Cedar Clinical Research selected as clinical research site for Beckley Psytech's Phase 2b Study
VANCOUVER, BC, Dec. 15, 2023. Numinus Wellness Inc. ( " Numinus " or the " Company " ), a mental health care company advancing traditional and innovative behavioral health treatments with a focus on safe, evidence-based psychedelic-assisted... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - December 16, 2023 Category: Pharmaceuticals Source Type: clinical trials
