A Trial to Learn if REGV131-LNP1265 is Safe and Works to Help the Body Make Clotting Factor in Pediatric, Adolescent and Adult Patients With Hemophilia B
Conditions: Hemophilia B Interventions: Drug: REGV131; Drug: LNP1265 Sponsors: Regeneron Pharmaceuticals; Intellia Therapeutics Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2024 Category: Research Source Type: clinical trials
Case and Use Scenario Study to Gain Knowledge on the User Needs for a Medical Device for Hemophilia A Monitoring
Conditions: Hemophilia A Interventions: Other: Case scenarios - questionnaire; Other: Case scenarios - Focus groups; Other: Use scenarios - Usability test; Other: Use scenarios - interview Sponsors: Enzyre B.V.; Indiana Hemophilia& Thrombosis Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials
Real-life Clinical FEIBA Samples Measured Using the Version A of the HemA EnzySystem
Conditions: Hemophilia A With Inhibitor; Hemophilia A Interventions: Diagnostic Test: Thrombin generation assay (EnzySystem HemA version A - whole blood); Diagnostic Test: Thrombin generation assay (Ceveron s100 (Technoclone) - fresh plasma); Diagnostic Test: Additional coagulation tests Sponsors: Enzyre B.V.; Instytut Hematologii i Transfuzjologii, Warschau, Poland Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Prevalence of Synovitis in Patients With Haemophilia A
Conditions: Haemophilia A; Synovitis; Hemophilia Arthropathy; Sonography Interventions: Diagnostic Test: Hemophilia Early Arthropathy Detection with Ultrasound (HEAD-US); Haemophilia joint health score (HJHS) Sponsors: University Hospital, Bonn; Swedish Orphan Biovitrum Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B)
Conditions: Healthy Participants; Hemophilia A; Hemophilia B Interventions: Drug: SR604; Drug: Placebo Sponsors: Equilibra Bioscience LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 5, 2024 Category: Research Source Type: clinical trials
Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study
Conditions: Hemophilia; Hemorrhage; Facelift Surgery Interventions: Drug: 1%Tranexamic acid with standard local; Drug: 3% TXA; Drug: 1% TXA with local plus 3% TXA-soaked pledgets Sponsors: University of Minnesota Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2024 Category: Research Source Type: clinical trials
Physiotherapy and Reaction Time in Hemophilia
Conditions: Hemophilia Arthropathy Interventions: Other: Home exercise; Other: Manual therapy; Device: Neuromuscular electrical stimulation; Other: Supervised exercise Sponsors: Yuzuncu Y ıl University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials
Pharmacokinetic-guided Dosing of Emicizumab
Conditions: Hemophilia A With Inhibitor; Hemophilia A Without Inhibitor; Hemophilia A, Severe; Adolescent; Child; Adult Interventions: Other: Emicizumab - PK-guided dose reduction; Other: Emicizumab - Dosis continuation group; Other: Emicizumab - Dose adjustment group Sponsors: Kathelijn Fischer; Erasmus Medical Center; Amsterdam University Medical Center; Leiden University Medical Center; Radboud University Medical Center; Maastricht University Medical Center; University Medical Center Groningen; HagaZiekenhuis; Dutch Society of Haemophilia Patients Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials
Efficacy and Safety of KN057 Prophylaxis in Patients With Haemophilia A or B With Inhibitors
Conditions: Hemophilia A With Inhibitor; Hemophilia B With Inhibitor Interventions: Drug: KN057 Sponsors: Suzhou Alphamab Co., Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials
A Clinical Study of Recombinant Human Coagulation Factor VIII for Injection in Patients With Severe Hemophilia A
Conditions: Hemophilia A Interventions: Drug: Recombinant human activated coagulation factor VIII for injection Sponsors: Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Study of a Gene Therapy Treatment for Hemophilia A
Conditions: Hemophilia A Interventions: Genetic: SPK-8011 Sponsors: Spark Therapeutics, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials
Safety and Efficacy of STSP-0601 in Adult Patients With Hemophilia A or B With Inhibitor
Conditions: Hemophilia Interventions: Drug: STSP-0601 for Injection Sponsors: Staidson (Beijing) Biopharmaceuticals Co., Ltd Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
Post-Marketing Surveillance (All Case Surveillance) on Treatment With Alhemo ® in Patients With Haemophilia A or Haemophilia B With Inhibitors
Conditions: Haemophilia A; Haemophilia B Interventions: Drug: Concizumab Sponsors: Novo Nordisk A/S Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
Changes in Intra-articular Parameters by Doppler Ultrasound in Patients With Hemophilic Ankle Arthropathy
Conditions: Hemophilia Interventions: Other: Manual therapy; Other: Placebo therapy Sponsors: Investigaci ón en Hemofilia y Fisioterapia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
Version Testing of EnzySystem Version A for Hemophilia A
Conditions: Hemophilia A Interventions: Diagnostic Test: Several assays Sponsors: Radboud University Medical Center; Enzyre B.V. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials
