A pilot study of antimicrobial effects and ototoxicity of a Norway spruce (Picea abies) resin-based canine otic rinse product
CONCLUSIONS AND CLINICAL RELEVANCE: The product may be an option in supportive care of COE because of antimicrobial effects and lack of ototoxic properties in a guinea pig model.PMID:38169122 | DOI:10.1111/vde.13229 (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 3, 2024 Category: Veterinary Research Authors: Elina Aimo-Koivisto Laura Punakallio Riikka J ärvinen Jouni Junnila Thomas Gr önthal Merja Rantala Source Type: research
A pilot study of antimicrobial effects and ototoxicity of a Norway spruce (Picea abies) resin-based canine otic rinse product
CONCLUSIONS AND CLINICAL RELEVANCE: The product may be an option in supportive care of COE because of antimicrobial effects and lack of ototoxic properties in a guinea pig model.PMID:38169122 | DOI:10.1111/vde.13229 (Source: Veterinary Dermatology)
Source: Veterinary Dermatology - January 3, 2024 Category: Veterinary Research Authors: Elina Aimo-Koivisto Laura Punakallio Riikka J ärvinen Jouni Junnila Thomas Gr önthal Merja Rantala Source Type: research
Lens-induced myopization and body weight in young guinea pigs
To investigate the relationship between body weight and Axial length in guinea pigs. (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - January 3, 2024 Category: Opthalmology Authors: Hao-Tian Wu, Xu-Han Shi, Li Dong, Rui-Heng Zhang, Yi-Tong Li and Wen-Bin Wei Tags: Research Source Type: research
Indirubin mediates adverse intestinal reactions in guinea pigs by downregulating the expression of AchE through AhR
This study showed that the inhibition of AchE expression by indirubin plays a key role in the occurrence of adverse reactions to indirubin and that the underlying mechanism is related to AhR-mediated AchE downregulation.PMID:38164702 | DOI:10.1080/00498254.2023.2297745 (Source: Xenobiotica)
Source: Xenobiotica - January 2, 2024 Category: Research Authors: Xiaoting Xu Reham Taha Chenghan Chu Li Xiao Tao Wang Xinzhi Wang Xin Huang Zhenzhou Jiang Lixin Sun Source Type: research
Sex differences in plasma metabolites in a guinea pig model of allergic asthma
This study aimed to find sex-related differences in metabolome measured by hydrogen-1 nuclear magnetic resonance ((1)H NMR) spectroscopy in healthy and ovalbumin (OVA)-sensitized guinea pigs. Adult male and female animals were divided into controls and OVA-sensitized groups. OVA-sensitization was performed by OVA systemic and inhalational administration within 14 days; on day 15, animals were killed by anesthetic overdose followed by exsanguination. Blood was taken and differential white blood cell count was measured. Left lung was saline-lavaged and differential cell count in the bronchoalveolar lavage fluid (BALF) was me...
Source: Cell Research - January 2, 2024 Category: Cytology Authors: R Barosova E Baranovicova J Adamcakova K Prso J Hanusrichterova D Mokra Source Type: research
Indirubin mediates adverse intestinal reactions in guinea pigs by downregulating the expression of AchE through AhR
This study showed that the inhibition of AchE expression by indirubin plays a key role in the occurrence of adverse reactions to indirubin and that the underlying mechanism is related to AhR-mediated AchE downregulation.PMID:38164702 | DOI:10.1080/00498254.2023.2297745 (Source: Xenobiotica)
Source: Xenobiotica - January 2, 2024 Category: Research Authors: Xiaoting Xu Reham Taha Chenghan Chu Li Xiao Tao Wang Xinzhi Wang Xin Huang Zhenzhou Jiang Lixin Sun Source Type: research
Sex differences in plasma metabolites in a guinea pig model of allergic asthma
This study aimed to find sex-related differences in metabolome measured by hydrogen-1 nuclear magnetic resonance ((1)H NMR) spectroscopy in healthy and ovalbumin (OVA)-sensitized guinea pigs. Adult male and female animals were divided into controls and OVA-sensitized groups. OVA-sensitization was performed by OVA systemic and inhalational administration within 14 days; on day 15, animals were killed by anesthetic overdose followed by exsanguination. Blood was taken and differential white blood cell count was measured. Left lung was saline-lavaged and differential cell count in the bronchoalveolar lavage fluid (BALF) was me...
Source: Physiological Research - January 2, 2024 Category: Physiology Authors: R Barosova E Baranovicova J Adamcakova K Prso J Hanusrichterova D Mokra Source Type: research
Sex differences in plasma metabolites in a guinea pig model of allergic asthma
This study aimed to find sex-related differences in metabolome measured by hydrogen-1 nuclear magnetic resonance ((1)H NMR) spectroscopy in healthy and ovalbumin (OVA)-sensitized guinea pigs. Adult male and female animals were divided into controls and OVA-sensitized groups. OVA-sensitization was performed by OVA systemic and inhalational administration within 14 days; on day 15, animals were killed by anesthetic overdose followed by exsanguination. Blood was taken and differential white blood cell count was measured. Left lung was saline-lavaged and differential cell count in the bronchoalveolar lavage fluid (BALF) was me...
Source: Physiological Research - January 2, 2024 Category: Physiology Authors: R Barosova E Baranovicova J Adamcakova K Prso J Hanusrichterova D Mokra Source Type: research
Sex differences in plasma metabolites in a guinea pig model of allergic asthma
This study aimed to find sex-related differences in metabolome measured by hydrogen-1 nuclear magnetic resonance ((1)H NMR) spectroscopy in healthy and ovalbumin (OVA)-sensitized guinea pigs. Adult male and female animals were divided into controls and OVA-sensitized groups. OVA-sensitization was performed by OVA systemic and inhalational administration within 14 days; on day 15, animals were killed by anesthetic overdose followed by exsanguination. Blood was taken and differential white blood cell count was measured. Left lung was saline-lavaged and differential cell count in the bronchoalveolar lavage fluid (BALF) was me...
Source: Physiological Research - January 2, 2024 Category: Physiology Authors: R Barosova E Baranovicova J Adamcakova K Prso J Hanusrichterova D Mokra Source Type: research
Sex differences in plasma metabolites in a guinea pig model of allergic asthma
This study aimed to find sex-related differences in metabolome measured by hydrogen-1 nuclear magnetic resonance ((1)H NMR) spectroscopy in healthy and ovalbumin (OVA)-sensitized guinea pigs. Adult male and female animals were divided into controls and OVA-sensitized groups. OVA-sensitization was performed by OVA systemic and inhalational administration within 14 days; on day 15, animals were killed by anesthetic overdose followed by exsanguination. Blood was taken and differential white blood cell count was measured. Left lung was saline-lavaged and differential cell count in the bronchoalveolar lavage fluid (BALF) was me...
Source: Physiological Research - January 2, 2024 Category: Physiology Authors: R Barosova E Baranovicova J Adamcakova K Prso J Hanusrichterova D Mokra Source Type: research
Low genetic diversity of < i > Treponema pallidum < /i > ssp. < i > pertenue < /i > (TPE) isolated from patients ’ ulcers in Namatanai District of Papua New Guinea: Local human population is infected by three TPE genotypes
by Monica Medappa, Petra Posp íšilová, Maria Paula M. Madruga, Lucy N. John, Camila G. Beiras, Linda Grillová, Jan Oppelt, Arka Banerjee, Marti Vall-Mayans, Oriol Mitjà, David Šmajs
Yaws is an endemic disease caused byTreponema pallidum subsp.pertenue (TPE) that primarily affects children in rural regions of the tropics. The endemic character of yaws infections and the expected exclusive reservoir of TPE in humans opened a new opportunity to start a yaws eradication campaign. We have developed a multi-locus sequence typing (MLST) scheme for TPE isolates combining the previously published (TP0548, TP0488) and new (TP...
Source: PLoS Neglected Tropical Diseases - January 2, 2024 Category: Tropical Medicine Authors: Monica Medappa Source Type: research
The Application and Integration of Evidence-Based Best Practice Standards to Healthcare Simulation Design: A Scoping Review
Simulation-based education (SBE) is an effective way to teach healthcare students clinical knowledge and skills. In nursing, SBE was favored during the recent pandemic to prepare nursing students for clinical placements (Wands, Geller,& Hallman, 2020) and in some American States simulation may replace up to 50% of required direct patient care contact hours (Curry-Lourenco et al., 2022). This was not the situation in Australia and New Zealand (NZ) nursing where accreditation bodies stipulated direct patient care hours were to remain in authentic settings (Australian Nursing& Midwifery Accreditation Council, 2021; Nursing Co...
Source: Clinical Simulation in Nursing - December 29, 2023 Category: Nursing Authors: Melanie Barlow, Leeanne Heaton, Colleen Ryan, Terri Downer, Kerry Reid-Searl, Stephen Guinea, Robyn Dickie, Alexandra Wordsworth, Philip Hawes, Aimee Lamb, Patrea Andersen Tags: Review Article Source Type: research
Immunogenicity and Therapeutic Efficacy of a Sendai-Virus-Vectored HSV-2 Vaccine in Mouse and Guinea Pig Models
CONCLUSIONS: The replication-defective recombinant Sendai viruses conveying HSV-2-gD and ICP27 proteins showed great immunogenicity and potential for preventing recurrent HSV-2 disease.PMID:38140157 | DOI:10.3390/vaccines11121752 (Source: Herpes)
Source: Herpes - December 23, 2023 Category: Infectious Diseases Authors: Xiuxiu Ren Wenhao Su Shishi Li Tingting Zhao Qiufang Huang Yinan Wang Xiaojie Wang Xiaohuan Zhang Jiangbo Wei Source Type: research
Immunogenicity and Therapeutic Efficacy of a Sendai-Virus-Vectored HSV-2 Vaccine in Mouse and Guinea Pig Models
CONCLUSIONS: The replication-defective recombinant Sendai viruses conveying HSV-2-gD and ICP27 proteins showed great immunogenicity and potential for preventing recurrent HSV-2 disease.PMID:38140157 | PMC:PMC10747028 | DOI:10.3390/vaccines11121752 (Source: Herpes)
Source: Herpes - December 23, 2023 Category: Infectious Diseases Authors: Xiuxiu Ren Wenhao Su Shishi Li Tingting Zhao Qiufang Huang Yinan Wang Xiaojie Wang Xiaohuan Zhang Jiangbo Wei Source Type: research
Isolation, Culture, and Microscopic Imaging of Guinea Pig Primary Gastric Tissue Cells
Methods Mol Biol. 2024;2749:65-71. doi: 10.1007/978-1-0716-3609-1_6.ABSTRACTIn this chapter, the procedure of isolation and propagation of guinea pig gastric tissue primary cells in cell culture in vitro is presented. Selected methods of microscopic imaging of cells are shown, including monitoring the ability of cells to migrate as a determinant of their activity. The primary cells that expanded in cell cultures in vitro have characteristics of natural cells and facilitate studying both the spontaneous and induced biological processes on the cellular level. Particularly, the primary cells derived from the guinea pig stomac...
Source: Mol Biol Cell - December 22, 2023 Category: Molecular Biology Authors: Weronika Gonciarz Magdalena Chmiela Source Type: research
