Evaluation of the Antimicrobial Activity of Phytochemicals from Tea and Agarwood Leaf Extracts against Isolated Bacteria from Poultry and Curd
In this study, tea and agarwood leaf extracts were analyzed for their antimicrobial activity against both pathogenic and beneficial bacteria. Fresh tea (Camellia sinensis) leaves were collected in three varieties, namely, BT-6 from Sylhet, BT-7 from Moulvibazar, and BT-8 from Habiganj; also, green tea (nonfermented tea), black tea (fully fermented tea), and agarwood (Aquilaria malaccensis) were collected from Sylhet region of Bangladesh. Unlike commercial antibiotics, which have side effects on probiotics (beneficiary bacteria), leaf extract activities were analyzed to check if they had positive effects on probiotics that ...
Source: The Scientific World Journal - November 29, 2023 Category: Science Authors: Shah Rucksana Akhter Urme Syeda Fahmida Ahmed Mohammed Mostafa Al Quadir Mst Rubaiat Nazneen Akhand Mohammad Mehedi Hasan Khan Source Type: research

Molecules, Vol. 28, Pages 7832: ( & minus;)-Epigallocatechin-3-Gallate Reduces Perfluorodecanoic Acid-Exacerbated Adiposity and Hepatic Lipid Accumulation in High-Fat Diet-Fed Male C57BL/6J Mice
Molecules, Vol. 28, Pages 7832: (−)-Epigallocatechin-3-Gallate Reduces Perfluorodecanoic Acid-Exacerbated Adiposity and Hepatic Lipid Accumulation in High-Fat Diet-Fed Male C57BL/6J Mice Molecules doi: 10.3390/molecules28237832 Authors: Hong Xu Xu Zhong Taotao Wang Shanshan Wu Huanan Guan Dongxu Wang Perfluorodecanoic acid (PFDA), an enduring and harmful organic pollutant, is widely employed in diverse food-related sectors. Our previous studies have provided evidence that PFDA has the potential to facilitate obesity and hepatic fat accumulation induced by high-fat diet (HFD) intake. Epigallocate...
Source: Molecules - November 28, 2023 Category: Chemistry Authors: Hong Xu Xu Zhong Taotao Wang Shanshan Wu Huanan Guan Dongxu Wang Tags: Article Source Type: research

Dual action of epigallocatechin-3-gallate in virus-induced cell Injury
CONCLUSIONS: The EGCG has proven to be an efficient antiviral against SARS-CoV-2 and HSV-2, as well as a wound-healing phytochemical. We assume that EGCG may be a promising option for slowing the course of acute cellular damage induced by systemic (Coronavirus Disease 2019 (COVID-19)) or topical (HSV-2) viral infections.PMID:38012348 | DOI:10.1186/s43141-023-00624-4 (Source: Herpes)
Source: Herpes - November 27, 2023 Category: Infectious Diseases Authors: Ahmed Mostafa Gomaa Mostafa-Hedeab Hany Abdelfattah Elhady Esraa Ahmed Mohamed Abozer Y Eledrdery Sager Holyl Alruwaili Ahmed Mohamed Al-Abd Abdou Kamal Allayeh Source Type: research

Molecules, Vol. 28, Pages 7775: Azorean Black Tea (Camellia sinensis) Antidermatophytic and Fungicidal Properties
a Gonçalves The treatment of dermatophytoses, the most common human fungal infections, requires new alternatives. The aim of this study was to determine the antidermatophytic activity of the aqueous Azorean Black Tea extract (ABT), together with an approach to the mechanisms of action. The phytochemical analysis of ABT extract was performed by HPLC. The dermatophytes susceptibility was assessed using a broth microdilution assay; potential synergies with terbinafine and griseofulvin were evaluated by the checkerboard assay. The mechanism of action was appraised by the quantification of the fungal cell wall chitin and &...
Source: Molecules - November 25, 2023 Category: Chemistry Authors: Chantal Fernandes Jos é Sousa-Baptista Ana Filipa Lenha-Silva Daniela Calheiros Edmilson Correia Artur Figueirinha L ígia Salgueiro Teresa Gon çalves Tags: Article Source Type: research

Bioequivalence of 240  mg Apalutamide Tablets and Preparation in Aqueous Food Vehicles for Alternative Administration
AbstractA 240-mg single tablet has been developed with the focus of reducing the pill burden of the apalutamide daily dose of 240  mg (4 × 60-mg tablets). An open-label, randomized, single-dose phase 1 study with a 2-sequence and 2-period crossover design in healthy men determined the bioequivalence of a 240-mg single tablet versus the currently available 4 × 60-mg tablets (Part 1, N = 74) and assessed effect of a high- fat meal (Part 2, N = 21) on apalutamide maximum plasma concentration (Cmax) and the area under the plasma concentration-time curve (AUC0-72  h). The 90% confidence interval of geometric mean ratios...
Source: Clinical Pharmacology in Drug Development - November 21, 2023 Category: Drugs & Pharmacology Authors: Alex Yu, Mieke Van Uffel, Juhui J. Jiao, Rosamerlinda Rosales, Maura Erba, Nahor Haddish ‐Berhane Tags: Original Article Source Type: research

Epigallocatechin gallate delays age-related cataract development via the RASSF2/AKT pathway
In this study, we found for the first time the retarding effect of EGCG on lens clouding in mice and revealed the mechanism of action of RASSF2/AKT in it, which provides a theoretical basis for the targeted treatment of EGCG.PMID:37979829 | DOI:10.1016/j.ejphar.2023.176204 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - November 18, 2023 Category: Drugs & Pharmacology Authors: Shanhe Liu Dongmei Su Zhaoyi Sun Tianhua Piao Sijia Li Lina Guan Yanjiang Fu Gaobo Zhang Tingsong Cui Wenna Zhu Xu Ma Shanshan Hu Source Type: research

Long-term green-Mediterranean diet may favor fasting morning cortisol stress hormone; The DIRECT-PLUS clinical trial
Conclusions: Long-term adherence to MED diets, and mainly green-MED/high polyphenols diet, may lower FMC, stress hormone, levels,. Lifestyle-induced FMC decrease may have potential benefits related to cardiometabolic health, irrespective of weight loss. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - November 14, 2023 Category: Endocrinology Source Type: research

Green tea waste-derived carbon dots: efficient degradation of RhB dye and selective sensing of Cu < sup > 2+ < /sup > ions
Environ Sci Pollut Res Int. 2023 Nov 13. doi: 10.1007/s11356-023-30735-x. Online ahead of print.ABSTRACTHerein, we have synthesized carbon dots (CDs) using a one-step hydrothermal method from green tea waste, a biomass-derived source with high fluorescent properties and excellent solubility in water. The synthesis of CDs was confirmed through a comprehensive range of characterization techniques, including HRTEM (high-resolution transmission electron microscopy), XPS (X-ray photoelectron spectroscopy), and EDX (energy-dispersive X-ray spectroscopy). The optical properties of the synthesized CDs were assessed using UV-Vis sp...
Source: Environmental Science and Pollution Research International - November 13, 2023 Category: Environmental Health Authors: None Qurtulen Anees Ahmad Source Type: research