Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta
CONCLUSION: In conclusion, our findings suggest that BKCa, IKCa, Kv, KATP, Kir, and K2P channels are involved in the vasorelaxant effect mechanisms of apelin in the rat thoracic aorta.PMID:35578855 | DOI:10.2174/0929866529666220516141317 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - May 17, 2022 Category: Biochemistry Authors: Serdar Sahinturk Sadettin Demirel Naciye Isbil Fadil Ozyener Source Type: research
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta
CONCLUSION: In conclusion, our findings suggest that BKCa, IKCa, Kv, KATP, Kir, and K2P channels are involved in the vasorelaxant effect mechanisms of apelin in the rat thoracic aorta.PMID:35578855 | DOI:10.2174/0929866529666220516141317 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - May 17, 2022 Category: Biochemistry Authors: Serdar Sahinturk Sadettin Demirel Naciye Isbil Fadil Ozyener Source Type: research
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta
CONCLUSION: In conclusion, our findings suggest that BKCa, IKCa, Kv, KATP, Kir, and K2P channels are involved in the vasorelaxant effect mechanisms of apelin in the rat thoracic aorta.PMID:35578855 | DOI:10.2174/0929866529666220516141317 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - May 17, 2022 Category: Biochemistry Authors: Serdar Sahinturk Sadettin Demirel Naciye Isbil Fadil Ozyener Source Type: research
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta
CONCLUSION: In conclusion, our findings suggest that BKCa, IKCa, Kv, KATP, Kir, and K2P channels are involved in the vasorelaxant effect mechanisms of apelin in the rat thoracic aorta.PMID:35578855 | DOI:10.2174/0929866529666220516141317 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - May 17, 2022 Category: Biochemistry Authors: Serdar Sahinturk Sadettin Demirel Naciye Isbil Fadil Ozyener Source Type: research
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta
CONCLUSION: In conclusion, our findings suggest that BKCa, IKCa, Kv, KATP, Kir, and K2P channels are involved in the vasorelaxant effect mechanisms of apelin in the rat thoracic aorta.PMID:35578855 | DOI:10.2174/0929866529666220516141317 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - May 17, 2022 Category: Biochemistry Authors: Serdar Sahinturk Sadettin Demirel Naciye Isbil Fadil Ozyener Source Type: research
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta
CONCLUSION: In conclusion, our findings suggest that BKCa, IKCa, Kv, KATP, Kir, and K2P channels are involved in the vasorelaxant effect mechanisms of apelin in the rat thoracic aorta.PMID:35578855 | DOI:10.2174/0929866529666220516141317 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - May 17, 2022 Category: Biochemistry Authors: Serdar Sahinturk Sadettin Demirel Naciye Isbil Fadil Ozyener Source Type: research
Brain Targeting, Antioxidant Polymeric Nanoparticles for Stroke Drug Delivery and Therapy
This study develops nanoparticles (NPs) consisting of a reactive oxygen species (ROS)-reactive polymer and further engineers them for targeted drug delivery to the ischemic brain through ligand-mediated interaction and thrombin-triggered shrinkability. It is demonstrated that the resulting NPs can efficiently deliver glyburide to the brain for effective stroke treatment. AbstractIschemic stroke is a leading cause of death and disability and remains without effective treatment options. Improved treatment of stroke requires efficient delivery of multimodal therapy to ischemic brain tissue with high specificity. Here, this ar...
Source: Small - March 20, 2022 Category: Nanotechnology Authors: Haoan Wu,
Bin Peng,
Farrah S. Mohammed,
Xingchun Gao,
Zhenpeng Qin,
Kevin N. Sheth,
Jiangbing Zhou,
Zhaozhong Jiang Tags: Research Article Source Type: research
Prescribing patterns and outcomes among patients treated for gestational diabetes mellitus
This study aimed to identify the most commonly prescribed agents for treating GDM, along with the maternal and fetal outcomes associated with their use. Electronic medical records were used to identify the medications prescribed for GDM at a large health system. Data were collected comparing medication failure rate, maternal weight gain, and incidence of fetal macrosomia, neonatal hypoglycemia, and premature delivery between the agents used. Of the 368 patients who met the inclusion criteria, 76.9% were initiated on glyburide, 13.6% were initiated on metformin, 8.2% were initiated on insulin, and 1.4% were initiated on a c...
Source: Baylor University Medical Center Proceedings - March 9, 2022 Category: Universities & Medical Training Authors: Heather Hay Delaney Ivy Kiumars Zolfaghari Source Type: research
Prescribing patterns and outcomes among patients treated for gestational diabetes mellitus
This study aimed to identify the most commonly prescribed agents for treating GDM, along with the maternal and fetal outcomes associated with their use. Electronic medical records were used to identify the medications prescribed for GDM at a large health system. Data were collected comparing medication failure rate, maternal weight gain, and incidence of fetal macrosomia, neonatal hypoglycemia, and premature delivery between the agents used. Of the 368 patients who met the inclusion criteria, 76.9% were initiated on glyburide, 13.6% were initiated on metformin, 8.2% were initiated on insulin, and 1.4% were initiated on a c...
Source: Baylor University Medical Center Proceedings - March 9, 2022 Category: Universities & Medical Training Authors: Heather Hay Delaney Ivy Kiumars Zolfaghari Source Type: research
Prescribing patterns and outcomes among patients treated for gestational diabetes mellitus
This study aimed to identify the most commonly prescribed agents for treating GDM, along with the maternal and fetal outcomes associated with their use. Electronic medical records were used to identify the medications prescribed for GDM at a large health system. Data were collected comparing medication failure rate, maternal weight gain, and incidence of fetal macrosomia, neonatal hypoglycemia, and premature delivery between the agents used. Of the 368 patients who met the inclusion criteria, 76.9% were initiated on glyburide, 13.6% were initiated on metformin, 8.2% were initiated on insulin, and 1.4% were initiated on a c...
Source: Baylor University Medical Center Proceedings - March 9, 2022 Category: Universities & Medical Training Authors: Heather Hay Delaney Ivy Kiumars Zolfaghari Source Type: research
Prescribing patterns and outcomes among patients treated for gestational diabetes mellitus
This study aimed to identify the most commonly prescribed agents for treating GDM, along with the maternal and fetal outcomes associated with their use. Electronic medical records were used to identify the medications prescribed for GDM at a large health system. Data were collected comparing medication failure rate, maternal weight gain, and incidence of fetal macrosomia, neonatal hypoglycemia, and premature delivery between the agents used. Of the 368 patients who met the inclusion criteria, 76.9% were initiated on glyburide, 13.6% were initiated on metformin, 8.2% were initiated on insulin, and 1.4% were initiated on a c...
Source: Baylor University Medical Center Proceedings - March 9, 2022 Category: Universities & Medical Training Authors: Heather Hay Delaney Ivy Kiumars Zolfaghari Source Type: research
Prescribing patterns and outcomes among patients treated for gestational diabetes mellitus
This study aimed to identify the most commonly prescribed agents for treating GDM, along with the maternal and fetal outcomes associated with their use. Electronic medical records were used to identify the medications prescribed for GDM at a large health system. Data were collected comparing medication failure rate, maternal weight gain, and incidence of fetal macrosomia, neonatal hypoglycemia, and premature delivery between the agents used. Of the 368 patients who met the inclusion criteria, 76.9% were initiated on glyburide, 13.6% were initiated on metformin, 8.2% were initiated on insulin, and 1.4% were initiated on a c...
Source: Baylor University Medical Center Proceedings - March 9, 2022 Category: Universities & Medical Training Authors: Heather Hay Delaney Ivy Kiumars Zolfaghari Source Type: research
Prescribing patterns and outcomes among patients treated for gestational diabetes mellitus
This study aimed to identify the most commonly prescribed agents for treating GDM, along with the maternal and fetal outcomes associated with their use. Electronic medical records were used to identify the medications prescribed for GDM at a large health system. Data were collected comparing medication failure rate, maternal weight gain, and incidence of fetal macrosomia, neonatal hypoglycemia, and premature delivery between the agents used. Of the 368 patients who met the inclusion criteria, 76.9% were initiated on glyburide, 13.6% were initiated on metformin, 8.2% were initiated on insulin, and 1.4% were initiated on a c...
Source: Baylor University Medical Center Proceedings - March 9, 2022 Category: Universities & Medical Training Authors: Heather Hay Delaney Ivy Kiumars Zolfaghari Source Type: research
Prescribing patterns and outcomes among patients treated for gestational diabetes mellitus
This study aimed to identify the most commonly prescribed agents for treating GDM, along with the maternal and fetal outcomes associated with their use. Electronic medical records were used to identify the medications prescribed for GDM at a large health system. Data were collected comparing medication failure rate, maternal weight gain, and incidence of fetal macrosomia, neonatal hypoglycemia, and premature delivery between the agents used. Of the 368 patients who met the inclusion criteria, 76.9% were initiated on glyburide, 13.6% were initiated on metformin, 8.2% were initiated on insulin, and 1.4% were initiated on a c...
Source: Baylor University Medical Center Proceedings - March 9, 2022 Category: Universities & Medical Training Authors: Heather Hay Delaney Ivy Kiumars Zolfaghari Source Type: research