Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed. The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Viral Infection in Middle Age Correlates with Later Dementia Risk
A range of evidence suggests that persistent viral infection contributes to the risk of suffering neurodegenerative conditions such as Alzheimer's disease. This may be due to mechanisms relating to amyloid-β accumulation, in its role as an anti-microbial peptide, a part of the innate immune system. It may have more to do with lasting chronic inflammation subsequent to infection. Researchers here note another addition to the epidemiological data on this topic, in this case linking severe infections requiring hospitalization with later dementia risk. The effect sizes here are large and last for a long time following infecti...
Source: Fight Aging! - February 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

TWiV 869: Epstein-Barr virus and MS, a perfect storm
TWiV reviews epidemiological and experimental evidence that infection with Epstein-Barr virus leads to the production of antibodies against a viral protein that cross-react with a human protein, leading to multiple sclerosis. (Source: virology blog)
Source: virology blog - February 25, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Epstein-Barr virus molecular mimicry mononucleosis multiple sclerosis viral viruses Source Type: blogs

Kissing disease ’s link to multiple sclerosis
In recent decades, mounting evidence has suggested the Epstein-Barr virus (EBV), a ubiquitous member of the herpes family that causes infectious mononucleosis (a.k.a. the“kissing disease”), can cause multiple sclerosis (MS). Last month, a study published in the journal Science went even further, citing EBV infection as likely the leading cause of MS. It isRead more …Kissing disease’s link to multiple sclerosis originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 21, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/hoag-memorial-hospital-presbyterian" rel="tag" > Hoag Memorial Hospital Presbyterian < /a > < /span > Tags: Conditions Infectious Disease Source Type: blogs

Trial By Error: Swedish ME Patient Fears Forced Psychiatric Treatment
By David Tuller, DrPH Holger Klintenberg, a 35-year-old from the southern Swedish city of Jonkoping, has severe ME. His illness began after a bout of mononucleosis (or glandular fever) when he was 19. He has recently experienced difficult interactions with the health care system. His family fears he could be forced into psychiatric care against […] (Source: virology blog)
Source: virology blog - December 30, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Trial By Error: Update on BMJ ’ s CBT-Music Therapy Study (h/t Steinkopf and Tack)
By David Tuller, DrPH I have written multiple posts this year about a Norwegian study of cognitive behavior therapy plus music therapy as a treatment for chronic fatigue after acute EBV infection (aka mononucleosis and glandular fever). The study, published in April by BMJ Paediatrics Open, was rife with methodological and ethical flaws. It should not have […] (Source: virology blog)
Source: virology blog - November 24, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT music therapy Nina Steinkopf norway Tack Source Type: blogs

Long COVID: 8 Ways Digital Health Can Address The Symptoms
Yes, the COVID-19 pandemic is long. Since the WHO characterised the virus’ spread as a pandemic in March, cases have been climbing; countries are facing a second wave and are entering lockdown 2.0; and many aspects of our current lifestyle will continue through 2021. But this isn’t what we mean by “long COVID.” This newly-minted term refers to patients experiencing long-term sequelae of a COVID infection. It’s not an exact medical term as it is a patient-made one apparently first used by Elisa Perego in a tweet to describe her own experience. Additionally, two patients can have different #longcovid experiences...
Source: The Medical Futurist - November 17, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine E-Patients Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI diabetes lumosity wearables sleep tracking Fitbit mental heal Source Type: blogs

Our Top 8 Digital Health Solutions Addressing Long COVID
Yes, the COVID-19 pandemic is long. Since the WHO characterised the virus’ spread as a pandemic in March, cases have been climbing; countries are facing a second wave and are entering lockdown 2.0; and many aspects of our current lifestyle will continue through 2021. But this isn’t what we mean by “long COVID.” This newly-minted term refers to patients experiencing long-term sequelae of a COVID infection. It’s not an exact medical term as it is a patient-made one apparently first used by Elisa Perego in a tweet to describe her own experience. Additionally, two patients can have different #longcovid experiences...
Source: The Medical Futurist - November 17, 2020 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: Artificial Intelligence in Medicine E-Patients Health Sensors & Trackers Healthcare Design Healthcare Policy Portable Medical Diagnostics Telemedicine & Smartphones AI diabetes lumosity wearables sleep tracking Fitbit mental heal Source Type: blogs

The tragedy of the post-COVID “ long haulers ”
Suppose you are suddenly are stricken with COVID-19. You become very ill for several weeks. On awakening every morning, you wonder if this day might be your last. And then you begin to turn the corner. Every day your worst symptoms — the fever, the terrible cough, the breathlessness — get a little better. You are winning, beating a life-threatening disease, and you no longer wonder if each day might be your last. In another week or two, you’ll be your old self. But weeks pass, and while the worst symptoms are gone, you’re not your old self — not even close. You can’t meet your responsibilities at home or at wor...
Source: Harvard Health Blog - October 15, 2020 Category: Consumer Health News Authors: Anthony Komaroff, MD Tags: Brain and cognitive health Coronavirus and COVID-19 Fatigue Source Type: blogs

Trial By Error: Columbia Experts Urge BMJ to Retract Problem-Plagued Study
By David Tuller, DrPH On Thursday, Professors Vincent Racaniello and Mady Hornig, both from Columbia University, wrote to BMJ’s research integrity coordinator. I have been corresponding with BMJ, and specifically the research integrity coordinator, about the Norwegian study of cognitive behavior therapy combined with music therapy as a treatment for chronic fatigue in adolescents after […] (Source: virology blog)
Source: virology blog - July 25, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT mononucleosis music therapy norway Source Type: blogs

Trial By Error: Columbia Experts Urge BMJ to Retract Not-Fully-Reviewed Study
By David Tuller, DrPH On Thursday, Professors Vincent Racaniello and Mady Hornig, both from Columbia University, wrote to BMJ’s research integrity coordinator. I have been corresponding with BMJ, and specifically the research integrity coordinator, about the Norwegian study of cognitive behavior therapy combined with music therapy as a treatment for chronic fatigue in adolescents after […] (Source: virology blog)
Source: virology blog - July 25, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized BMJ CBT mononucleosis music therapy norway Source Type: blogs

Trial By Error: Another Letter About BMJ ’ s Music Therapy Study
By David Tuller, DrPH I am still waiting for answers from BMJ about the Norwegian study of cognitive behavior therapy plus music therapy for treatment of chronic fatigue in adolescents after mononucleosis. The study was published in BMJ Paediatrics Open. I have written about it here. This morning I sent the following letter to the […] (Source: virology blog)
Source: virology blog - July 21, 2020 Category: Virology Authors: David Tuller Tags: David Tuller ME/CFS BMJ CBT music therapy norway Source Type: blogs

Trial By Error: My Letter to Senior Author of Norway ’ s CBT-Music Therapy Study
By David Tuller, DrPH In the past week, I have written three posts about a Norwegian study of cognitive behavior therapy plus music therapy for adolescents with chronic fatigue after acute Epstein-Barr virus infection–an illness known as mononucleosis in the US and glandular fever in the UK. The corresponding author of the study is Vegard […] (Source: virology blog)
Source: virology blog - May 22, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Trial By Error: An Australian Radio Interview with Melbourne ’ s Dr Mark Guthridge
By David Tuller, DrPH When I was in Australia two years ago–wow, can’t believe it’s been that long!–I spent some time with Dr Mark Guthridge, an associate professor of biomedical science at Deakin University in Melbourne. Several years ago, after a bout of mononucleosis/glandular fever, he developed myalgic encephalomyelitis, which in Australia even patients and […] (Source: virology blog)
Source: virology blog - February 19, 2020 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs