Endoscopic transorbital approach in children: surgical technique and early results
CONCLUSIONS: In select cases, the ETOA can be considered a minimally invasive alternative for conventional skull base approaches in the armamentarium of pediatric skull base surgery. Further investigation and the accumulation of experience are warranted in the future to enhance the efficacy and applicability of the ETOA in pediatric patients.PMID:38560935 | DOI:10.3171/2024.1.FOCUS23858 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - April 1, 2024 Category: Neurosurgery Authors: Chiman Jeon Kyuha Chong Hyung Jin Shin Doo-Sik Kong Source Type: research
Abnormal Bone Turnover Observed in Obese Children Based on Puberty Stage -Specific Bone Turnover Marker Reference
CONCLUSIONS: We provide age-, sex-, and puberty stage-specific P1NP and β-CTX reference curve. According to these, obesity appeared to be a negative factor for bone formation in boys and for bone resorption in girls.PMID:38557870 | DOI:10.1210/clinem/dgae206 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 1, 2024 Category: Endocrinology Authors: Chushan Wu Zhuoguang Li Yanyan Li Xiu Zhao Yue Shang Rongfei Zheng Qiru Su Yan Li Rongyin Fu Wenlong Lu Jingfan Xiong Zhe Su Source Type: research
Associations of Serum Irisin and Fibroblast Growth Factor-21 Levels With Bone Mineral Characteristics in Eumenorrheic Adolescent Athletes With Different Training Activity Patterns
CONCLUSIONS: Serum irisin and FGF-21 levels were not different between adolescent eumenorrheic girls with different training activity patterns. FGF-21 was positively associated with lumbar spine areal bone mineral density, which predominantly consists of trabecular bone in adolescent rhythmic gymnasts.PMID:38560997 | DOI:10.1123/pes.2023-0166 (Source: Pediatric Exercise Science)
Source: Pediatric Exercise Science - April 1, 2024 Category: Pediatrics Authors: Jaak J ürimäe Liina Remmel Anna-Liisa Tamm Priit Purge Katre Maasalu Vallo Tillmann Source Type: research
A novel < em > LTBP2 < /em > gene variant in a Turkish family with juvenile-onset open-angle glaucoma
CONCLUSION: We documented a novel missense mutation in the LTBP2 gene leading to a severe form of JOAG with refractory IOP and progressive optic nerve damage, which seems to show autosomal recessive inheritance.PMID:38557215 | DOI:10.1080/13816810.2024.2331540 (Source: Ophthalmic Genetics)
Source: Ophthalmic Genetics - April 1, 2024 Category: Opthalmology Authors: Banu Bozkurt Ozkan Ba ğcı Sema Üzüm T ülin Çora Source Type: research
Endoscopic transorbital approach in children: surgical technique and early results
CONCLUSIONS: In select cases, the ETOA can be considered a minimally invasive alternative for conventional skull base approaches in the armamentarium of pediatric skull base surgery. Further investigation and the accumulation of experience are warranted in the future to enhance the efficacy and applicability of the ETOA in pediatric patients.PMID:38560935 | DOI:10.3171/2024.1.FOCUS23858 (Source: Neurosurgical Focus)
Source: Neurosurgical Focus - April 1, 2024 Category: Neurosurgery Authors: Chiman Jeon Kyuha Chong Hyung Jin Shin Doo-Sik Kong Source Type: research
Saccular abdominal aortic aneurysm in adolescence with tuberous sclerosis
Key clinical messageAbdominal aortic aneurysm complicated by tuberous sclerosis is rare, particularly in patients over the age of 10. It is important to screen for abdominal aortic aneurysm in adolescents diagnosed with tuberous sclerosis regularly.AbstractA 15-year-old girl who was diagnosed with tuberculous sclerosis complicated with a saccular aortic abdominal aneurysm (AAA), measuring 19 × 18 mm in diameter. The patient underwent open repair of AAA using a 11 mm straight prosthetic graft. It is important to screen for AAA in adolescents diagnosed with tuberous sclerosis regularly. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 1, 2024 Category: General Medicine Authors: Takumi Umibe,
Hironobu Nishiori,
Shintaro Koizumi,
Hiroki Ikeuchi,
Goro Matsumiya Tags: CASE IMAGE Source Type: research
Resting State Connectivity Networks Underpinning Multisite Pain in Adolescent Girls and Boys
Multisite pain disproportionately affects women and is associated with central nervous system dysregulation (i.e., nociplastic pain). As sex differences emerge during adolescence, there may be an intersection between neurodevelopmental sex differences and the neurobiology of nociplastic pain, but this has not been examined. The present study investigates sex differences in the neural networks underlying multisite pain using resting state fMRI data from the Adolescent Brain Cognitive Development Study (n=1,254, ages 11-12). (Source: The Journal of Pain)
Source: The Journal of Pain - April 1, 2024 Category: Materials Science Authors: Esmeralda Hidalgo-Lopez, Tristin Smith, Hannah Becker, Mike Angstadt, Andrew Schrepf, David A. Williams, Daniel Clauw, Steven E. Harte, Chelsea Kaplan, Adriene Beltz Source Type: research
15. Adverse Obstetrical Outcomes are Increased in Adolescent Pregnancy
Adolescent pregnancy is defined as pregnancy before the age of 20 and is the leading cause of mortality in girls ages 15 to 19 worldwide. Adolescent pregnancies are associated with increased maternal, obstetric, and neonatal risks, however data is limited. Our objective was to compare the risk of adverse obstetrical outcomes in teenage pregnancies to adult pregnancies. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Anna Scipioni, Holly VanDeman, Jean Paul Tanner, Jason Salemi, Jose Duncan Source Type: research
18. Case of an adolescent girl with familial vulvar leiomyoma
While uterine leiomyomas remain a common occurrence affecting nearly 30% of adult women above 35yo, leiomyomas can arise anywhere smooth muscle cells are located in the body. Vulvar leiomyomas are a particularly rare diagnosis, often misdiagnosed as Bartholin gland cyst, comprising 0.07% of vulvar tumors, and thought to arise from smooth muscle within the round ligament, erectile tissue, and dartos muscle. Even more rare is the presentation of vulvar leiomyoma in the adolescent population and family history of vulvar leiomyoma. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Madeline Ross, Charlene Dekonenko, Rebecca Rentea, Tazim Dowlut-McElroy Source Type: research
19. Case of complete androgen insensitivity syndrome with gonads containing rudimentary penile tissue and both Mullerian and Wolffian type structures
Complete androgen insensitivity (CAIS) is a disorder of sexual development (DSD). It is caused by a loss of function mutation in a person with a XY genotype, where testosterone has no effect on sexual development. It is inherited in an X-linked recessive pattern, and is typically discovered in amenorrhoeic women, or girls with cryptorchid gonads that come to medical attention. Generally, gonadectomy is recommended post-puberty on an individualized basis to prevent malignancy. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Courtney Schubert, Hailey Benoit, Camelia Stefanovici, Amanda Morris Source Type: research
27. Combinatory effects of unilateral oophorectomy plus cyclophosphamide treatment on ovarian reserve and fertility in a mouse model
Ovarian tissue cryopreservation via unilateral oophorectomy (ooph) prior to receiving gonadotoxic treatment is the gold standard for fertility preservation in pre-pubertal girls. The deleterious effects of cyclophosphamide (Cy) on ovarian follicles have been well studied, but it is not known how unilateral ooph in combination with Cy may influence ovarian function and risk of premature ovarian insufficiency. The aim of this study was to investigate the combined effects of unilateral ooph + Cy on AMH and ovarian follicles using a mouse model. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Elizabeth Varghese, Taylor Badger, Raghuveer Kavarthapu, Alexander Grinberg, Ramya Balasubramanian, Hong Lou, Maria De La Luz Sierra, Karl Pfeifer, Jacqueline Maher, Veronica Gomez-Lobo Source Type: research
57. Fistula Formation from Chronic Presence of a Vaginal Foreign Body
Small vaginal foreign bodies (FB) in adolescent girls are common, resulting in simple outpatient removal without major sequelae. However, persisting FBs can result in serious complications, such as becoming deeply embedded, perforations, fistula formation involving multiple organs, and needing complex surgeries. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Hareena Sangha, Sireesha Reddy, Jordan Brown, Erin Pickard Source Type: research
74. Labial Adhesion Mimicking a Persistent Urogenital Sinus in a Reproductive-Aged Woman: a Case Report
Labial adhesion is a condition generally associated with hypoestrogenic status of prepubertal girls but can also occur during reproductive years related to vulvar trauma (mutilation, delivery, sexual abuse) or inflammatory diseases (herpes, lichen, lupus). In severe and long-standing cases, it can mimic congenital anomalies, such as persistent urogenital sinus (PUS), when is difficult to distinguish the characteristic midline raphe of a fusion. The purpose of this case it to portray the difficulties of the differential diagnosis of persistent labial adhesions and congenital malformations. (Source: Journal of Pediatric and ...
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Maria Canessa, Alvaro Cerda, Andrea Huneeus, Mariane von M ühlenbrock Source Type: research
84. Mature Ovarian Dermoid Cyst Trajectory in Premenarchal Girls
This study aims to assess characteristics associated with expectant management (EM) vs surgical management (SM) in premenarchal patients, to assess growth rate of ODCs in patients expectantly managed, and to investigate rates of oophorectomy versus cystectomy in patients who had surgery (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Jasneet Aulakh, Erin Isaacson, Melina Dendrinos, Monica Rosen Source Type: research
96. Ovarian Torsion After Oophoropexy: A Retrospective Review Through the NASPAG Fellows Research Consortium
Pediatric ovarian torsion (OT) is rare and occurs more frequently in premenarchal girls, presumably due to prepubertal adnexal anatomy. There is little literature examining the rate of recurrent OT after oophoropexy (OP), though this operation is commonly performed to prevent OT and preserve the gonad. We sought to determine the rate of OT after OP (by plication or fixation) in a pediatric population to determine the success of OP for preventing recurrent OT. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Katherine Hayes, Amanda French, Ana Cisneros-Camacho, Angie Hamouie Source Type: research
