IJERPH, Vol. 19, Pages 5196: Effects of Olfactory Stimulation with Aroma Oils on Psychophysiological Responses of Female Adults
This study investigated the effects of olfactory stimulation with aroma oils on the psychophysiological responses in women. Ten aromatic oils (lavender, rosemary, rose, eucalyptus, jasmine, geranium, chamomile, clary sage, thyme, and peppermint) were used on 23 women aged between 20 and 60 years. They inhaled the scent for 90 s through a glass funnel attached to their lab apron, 10 cm below their nose, while the pump was activated. Electroencephalography, blood pressure, and pulse rate were measured before and during inhalation of the aroma oils. The relative alpha (RA) power spectrums indicating relaxation and resting sta...
Source: International Journal of Environmental Research and Public Health - April 25, 2022 Category: Environmental Health Authors: Na-Yoon Choi Yu-Tong Wu Sin-Ae Park Tags: Article Source Type: research
Enhancing Cytotoxicity of Tamoxifen Using < em > Geranium < /em > Oil
In this study, we used this assay to investigate the effects of Geranium oil on the cytotoxicity of the oestrogen receptor (ER) antagonist: tamoxifen (TMX). The results showed that Geranium oil augmented TMX-induced cell death in a dose-dependent manner without directly reducing the viability of GT1-7 cells. Cotreatment with Geranium oil and ER agonist β-estradiol (E2) attenuated the inhibition of GT1-7 cell growth. Moreover, Geranium oil and geraniol, a major constituent of Geranium oil, showed weak agonist activity on ERα and ERβ with geraniol augmenting TMX-induced cell death similar to that observed in Geranium oil....
Source: Evidence-based Complementary and Alternative Medicine - March 28, 2022 Category: Complementary Medicine Authors: Dai Mizuno Masahiro Kawahara Keiko Konoha-Mizuno Kentaro Yamazaki Source Type: research
Molecules, Vol. 27, Pages 1752: Laser Light Treatment Improves the Mineral Composition, Essential Oil Production and Antimicrobial Activity of Mycorrhizal Treated Pelargoniumgraveolens
In this study, we aimed to explore the synergistic impact of these two factors on P. graveolens. For this, we used four groups of surface-sterilized seeds: (1) control group1 (non-irradiated; non-colonized group); (2) control group2 (mycorrhizal colonized group); (3) helium-neon (He-Ne) laser-irradiated group; (4) mycorrhizal colonization coupled with He-Ne laser-irradiation group. Treated seeds were growing in artificial soil inculcated with Rhizophagus irregularis MUCL 41833, in a climate-controlled chamber. After 6 weeks, P. graveolens plants were checked for their phytochemical content and antibacterial potential. Lase...
Source: Molecules - March 8, 2022 Category: Chemistry Authors: Mohammad K. Okla Samina Rubnawaz Turki M. Dawoud Saud Al-Amri Mohamed A. El-Tayeb Mostafa A. Abdel-Maksoud Nosheen Akhtar Ahlem Zrig Gehad AbdElgayed Hamada AbdElgawad Tags: Article Source Type: research
The use of Dalmatian pyrethrum daisy and an excipient in the treatment of seborrheic dermatitis
Acta Biochim Pol. 2022 Feb 28. doi: 10.18388/abp.2020_5770. Online ahead of print.ABSTRACTThe active ingredients of the Pyretrin-D trichological cosmetic series, namely benzyl benzoate, Dalmatian pyrethrum daisy, Cistus incanus, tea tree oil and geranium oil, almond acid and arginine were tested in respect to the treatment of seborrheic dermatitis. The paper describes the application of Dalmatian pyrethrum daisy and the excipient. Methods and devices used to confirm the effectiveness of the tested formulations included the TrichoScope Polarizer Dino-Lite (MEDL4HM) and the scanning electron microscope (SEM).PMID:35225498 | ...
Source: Acta Biochim Pol - February 28, 2022 Category: Biochemistry Authors: Joannna Igielska-Kalwat Slawa Po łoczańska-Godek Ewa Kilian-Pi ęta Source Type: research
The use of Dalmatian pyrethrum daisy and an excipient in the treatment of seborrheic dermatitis
Acta Biochim Pol. 2022 Feb 28. doi: 10.18388/abp.2020_5770. Online ahead of print.ABSTRACTThe active ingredients of the Pyretrin-D trichological cosmetic series, namely benzyl benzoate, Dalmatian pyrethrum daisy, Cistus incanus, tea tree oil and geranium oil, almond acid and arginine were tested in respect to the treatment of seborrheic dermatitis. The paper describes the application of Dalmatian pyrethrum daisy and the excipient. Methods and devices used to confirm the effectiveness of the tested formulations included the TrichoScope Polarizer Dino-Lite (MEDL4HM) and the scanning electron microscope (SEM).PMID:35225498 | ...
Source: Acta Biochim Pol - February 28, 2022 Category: Biochemistry Authors: Joannna Igielska-Kalwat Slawa Po łoczańska-Godek Ewa Kilian-Pi ęta Source Type: research
Geraniin as a potential inhibitor of SARS-CoV-2 3CL < sup > pro < /sup >
Nat Prod Res. 2022 Feb 24:1-4. doi: 10.1080/14786419.2022.2043308. Online ahead of print.ABSTRACTGeraniin is a polyphenolic compound first isolated from Geranium thunbergii. The major protease (Mpro), namely 3 C-like protease (3CLpro), of coronaviruses is considered an attractive drug target as it is essential for the processing and maturation of viral polyproteins. Thus, our primary goal is to explore the efficiency of geraniin on 3CLpro of SARS-CoV-2 using the computational biology strategy. In this work, we studied the anti-coronavirus effect of geraniin in vitro and its potential inhibitory mode against the 3CLpro of S...
Source: Natural Product Research - February 24, 2022 Category: Biochemistry Authors: Wen-Di Yu Qi-Ying Jin Mao-Sen Zeng Jin-Yuan Liu Pei-Ping Xu Source Type: research
Geraniin as a potential inhibitor of SARS-CoV-2 3CL < sup > pro < /sup >
Nat Prod Res. 2022 Feb 24:1-4. doi: 10.1080/14786419.2022.2043308. Online ahead of print.ABSTRACTGeraniin is a polyphenolic compound first isolated from Geranium thunbergii. The major protease (Mpro), namely 3 C-like protease (3CLpro), of coronaviruses is considered an attractive drug target as it is essential for the processing and maturation of viral polyproteins. Thus, our primary goal is to explore the efficiency of geraniin on 3CLpro of SARS-CoV-2 using the computational biology strategy. In this work, we studied the anti-coronavirus effect of geraniin in vitro and its potential inhibitory mode against the 3CLpro of S...
Source: Natural Product Research - February 24, 2022 Category: Biochemistry Authors: Wen-Di Yu Qi-Ying Jin Mao-Sen Zeng Jin-Yuan Liu Pei-Ping Xu Source Type: research
Natural oils restore body weight, ameliorate serum bile acid and vitamin D and improve liver histology in depression
Khaled M.M. Koriem, Nevein N. Fadl, Salwa R. El-Zayat, Eman N. Hosny, Fatma A. Morsy
Nutrition & Food Science, Vol. ahead-of-print, No. ahead-of-print, pp.-
The purpose of this study was designed to investigate anise oil and geranium oil to amend body weight, serum bile acid and vitamin D, and liver histology in depressed rats.
Eighty male albino rats were divided into normal and depressed rats. Normal rats (40 rats) were divided into four equal groups: control, venlafaxine drug, anise oil and geranium oil groups. Depressed rats (40 rats) were divided into four equal groups: depressed ...
Source: Nutrition and Food Science - February 24, 2022 Category: Nutrition Authors: Khaled M.M. Koriem
Nevein N. Fadl
Salwa R. El-Zayat
Eman N. Hosny
Fatma A. Morsy Source Type: research
Geraniin inhibits whole blood IFN- γ and IL-6 and promotes IL-1β and IL-8, and stimulates calcium-dependent and sucrose-sensitive erythrocyte death
In conclusion, GRN regulates the WB cytokine response and promotes premature hemolysis and eryptosis. This study provides insights into the therapeutic utility of GRN in a highly relevant cellular model system.PMID:35026210 | DOI:10.1016/j.taap.2022.115881 (Source: Toxicology and Applied Pharmacology)
Source: Toxicology and Applied Pharmacology - January 13, 2022 Category: Toxicology Authors: Jawaher Alsughayyir Wafa Alshaiddi Roua Alsubki Amal Alshammary Ahmed M Basudan Mohammad A Alfhili Source Type: research
18KHT01, a Potent Anti-Obesity Polyherbal Formulation
Obesity is a life-threatening metabolic disorder necessitating urgent development of safe and effective therapy. Currently, limited such therapeutic measures are available for obesity. The present study was designed to develop a novel, safe and effective herbal therapy for the management of obesity. A polyherbal formulation (18KHT01) was developed by homogeneously mixing a specific proportion of crude Quercus acutissima (acorn jelly powder), Camellia sinensis (dry leaf buds), and Geranium thunbergii (dry aerial part) along with Citrus limon (fruit juice). Synergistic antioxidant, antiadipogenic, and anti-obesity activities...
Source: Frontiers in Pharmacology - December 17, 2021 Category: Drugs & Pharmacology Source Type: research
