Gastrointestinal Stromal Tumour (GIST) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Duodenal gastrointestinal stromal tumor presenting with life ‐threatening upper GI bleeding in a young patient: A case report and literature review
We present a case of a 31-year-old male patient presented with massive active hemateme sis and melena with hemorrhagic shock. The patient presented with massive hematemesis and melena of 1 h duration. Endoscopy showed pulsating active bleeding from the third part of the duodenum which was difficult to manage via endoscopy. Histopathologic evaluation showed spindle cell type GIST. In traoperatively, there was a nodular mass with active bleeding on the third part of the duodenum. Duodenectomy with end-to-end anastomosis was done. Discharged with no postoperative complication and was put on imatinib. There are considerable ...
Source: Clinical Case Reports - April 18, 2024 Category: General Medicine Authors: Samuel Addisu Abera, Amanuel Kassa Tadesse, Kirubel Addisu Abera, Kassa Berie Zegeye, Mohammed Alemu Ibrahim, Ashenafi Amsalu Feleke, Cheru lilay Gebrehiwet, Segenet Bizuneh Mengistu, Hirut Tesfahun Alemu, Yohannis Derbew Molla Tags: CASE REPORT Source Type: research

Adjuvant therapy for rare rectal gastrointestinal stromal tumors: A case report
Key Clinical MessageAnorectal gastrointestinal stromal tumors are extremely rare, constituting less than 0.1% of rectal tumors. Surgical resection using a transanal wide excision followed by adjuvant therapy with tyrosine kinase inhibitors can be a successful treatment combination to remove the mass and prevent recurrence while preserving the integrity of the anal sphincter.AbstractGastrointestinal stromal tumors (GISTs) are a rare subset of neoplasms, accounting for about 1% –2% of primary gastrointestinal malignancies. The stomach is the most common site for GISTs, with anorectal GISTs being exceptionally rare, represe...
Source: Clinical Case Reports - April 17, 2024 Category: General Medicine Authors: Ting ‐Yi Chu, Ta‐Wei Pu, Chao‐Yang Chen Tags: CASE REPORT Source Type: research

A rare case of extragastrointestinal stromal tumor of vocal cord - case report
We present a second case report of Extra-gastrointestinal stromal tumor of larynx a 47-year-old male reported to ENT Department Command Hospital Central Command Lucknow with complaints of Hoarseness. On examination found to have right vocal cord growth for which he underwent excision of right vocal cord growth. Histopathological examination showed typical of a spindle-cell GIST, showing strong immunoreactivity for CD 117, DOG1, Vimentin and CD 99. 6 months follow up post surgery with no recurrence. (Source: Indian Journal of Otolaryngology and Head and Neck Surgery)
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - April 16, 2024 Category: ENT & OMF Source Type: research

The advent of the first electric driven EUS-guided 17 gauge core needle biopsy - A pilot study on subepithelial lesions
CONCLUSIONS: By using an electric driven 17-G biopsy device, a true cylinder of core tissue can be obtained in one single puncture from the area of interest reducing the need for a second sampling. The absolute benefit of EUS-guided CNB is that the sample can be handled and histologically prepared in the same manner as standard percutaneous core needle sample, e.g., breast and prostate cancer.PMID:38618997 | DOI:10.1080/00365521.2024.2336611 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Fredrik Swahn Robert Glavas Lucin Hultin Malin Wickbom Source Type: research

Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study
ConclusionEven in a country where the costs of TKIs and follow-up care are covered by health insurance, financial difficulties can be present in GIST patients, especially in patients on TKI treatment, and may negatively influence the quality of life. (Source: Supportive Care in Cancer)
Source: Supportive Care in Cancer - April 10, 2024 Category: Cancer & Oncology Source Type: research

A new green fluorimetric micelle complexation approach for reduction of the consumed solvent and quantification of avapritinib in biological fluids
RSC Adv. 2024 Apr 2;14(15):10445-10451. doi: 10.1039/d4ra01198h. eCollection 2024 Mar 26.ABSTRACTAvapritinib (AVA) is the first medication authorized by the US-FDA in 2020 for the management of gastrointestinal stromal tumours (GISTs) that can't be treated by surgery. Cancer is among the most common causes of death worldwide and is the second most common cause of death after cardiovascular disease. Therefore, a quick, easy, sensitive, and straightforward fluorimetric approach was used to analyse AVA in pharmaceutical materials and blood plasma (pharmacokinetic). The suggested technique relies on 2% sodium dodecyl sulphate ...
Source: Adv Data - April 3, 2024 Category: Epidemiology Authors: Baher I Salman Hany A Batakoushy Roshdy E Saraya Mohamed A A Abdel-Aal Adel Ehab Ibrahim Yasser F Hassan Ahmed I Hassan Ehab A M El-Shoura Source Type: research

Case report: detection of multiple sporadic gastrointestinal stromal tumors by dual-time 18 F-FDG PET/CT
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors affecting the gastrointestinal tract. Typically, GISTs are solitary; however, in rare cases, they may be multiple and appear in one or more organs. Multiple GISTs can appear in familial GISTs, children, or certain tumor syndromes such as neurofibromatosis type 1, Carney syndrome, and Carney-Stratakis syndrome. However, the diagnosis of primary multiple sporadic GISTs is often more difficult than that of these diseases. Herein, we report a case of multiple primary sporadic GISTs in a 64-year-old man, affecting the abdominal cavity and retroperito...
Source: Frontiers in Oncology - March 28, 2024 Category: Cancer & Oncology Source Type: research

Emergent approach to small bowel tumors: diagnosis and treatment
CONCLUSION: Small bowel tumors frequently present with abdominal pain, bloating, and nausea and vomiting. CT and endoscopic procedures are the primary diagnostic tools. Small bowel cancers are often diagnosed late due to subtle clinical findings and the limitations of endoscopic imaging. Targeted screening strategies may be beneficial for certain at-risk and symptomatic patient groups. Early surgical intervention offers significant advantages for diagnosed patients.PMID:38506384 | DOI:10.14744/tjtes.2024.33680 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - March 20, 2024 Category: Emergency Medicine Authors: Enes Sahin Kaz ım Şahin Ha şim Köken Serta ç Ata Güler Turgay Şimşek Nihat Zafer Utkan Mustafa Şahin Source Type: research

Emergent approach to small bowel tumors: diagnosis and treatment
CONCLUSION: Small bowel tumors frequently present with abdominal pain, bloating, and nausea and vomiting. CT and endoscopic procedures are the primary diagnostic tools. Small bowel cancers are often diagnosed late due to subtle clinical findings and the limitations of endoscopic imaging. Targeted screening strategies may be beneficial for certain at-risk and symptomatic patient groups. Early surgical intervention offers significant advantages for diagnosed patients.PMID:38506384 | PMC:PMC10977489 | DOI:10.14744/tjtes.2024.33680 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - March 20, 2024 Category: Emergency Medicine Authors: Enes Sahin Kaz ım Şahin Ha şim Köken Serta ç Ata Güler Turgay Şimşek Nihat Zafer Utkan Mustafa Şahin Source Type: research