Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
MONDAY, Feb. 11, 2019 -- People with colon polyps spotted during screening are at higher risk for colon cancer. But while low-dose aspirin could lower the odds for the disease, too few patients adopt the regimen, new research shows. Advanced colon... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 11, 2019 Category: General Medicine Source Type: news

Aspirin to prevent colon cancer underutilized in high-risk patients
(Florida Atlantic University) The US Preventive Services Task Force (USPSTF) concluded that aspirin reduces the risk of colorectal cancer by 40 percent as well as recurrence of advanced polyps, which are a major risk factor. To explore whether high risk patients are adhering to USPSTF guidelines, FAU researchers analyzed data from structured interviews with 84 patients and found that less than half (42.9 percent) reported taking aspirin. These findings pose major challenges that require multifactorial approaches by physicians and patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 7, 2019 Category: Cancer & Oncology Source Type: news

Fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice
(Bentham Science Publishers) Recent epidemiological and experimental studies have shown that obesity is a major risk factor for Colorectal Cancer (CRC). Regular intake of high fat-containing diet can promote obesity and metabolic syndrome by increasing the insulin resistance and inflammatory response which contribute to carcinogenesis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 18, 2019 Category: Cancer & Oncology Source Type: news

Pseudopolyps Not Associated With Greater Colorectal Cancer Risk Pseudopolyps Not Associated With Greater Colorectal Cancer Risk
Post-inflammatory polyps (PIPs) are not associated with colorectal neoplasia (CRN) in patients with inflammatory bowel disease (IBD), according to new findings.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 20, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Post-Inflammatory Polyps Not Linked to Colorectal Neoplasia
FRIDAY, Dec. 14, 2018 -- For patients with inflammatory bowel disease (IBD), post-inflammatory polyps (PIPs) are associated with greater severity and extent of colon inflammation and higher rates of colectomy, but not with development of colorectal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 14, 2018 Category: Pharmaceuticals Source Type: news

Living With Cancer: When can you stop colon cancer screening?
Colon cancer screening: At what age can you stop? People older than 75 who have been getting regular colon cancer screening since age 50 and who have had consistently negative screenings ? no polyps or colon cancer, and who are not at an increased risk of colon cancer because of family history, may not need [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 14, 2018 Category: Databases & Libraries Source Type: news

Colorectal Cancer Screening Pill to Be in US Pilot Study
Check-Cap is getting one step closer to having its capsule-based screening method for colorectal cancer on the U.S. market. The Isfiya, Israel-based company has received FDA conditional approval for an IDE to initiate a pilot study of the C-Scan capsule. FDA’s conditional approval of the IDE requires Check-Cap to provide additional information to the agency and the company may begin enrolling patients immediately upon approval by the study site's Institutional Review Board (IRB). The trial will consist of up to 45 patients and it will be a single-arm study. Patients who are enrolled will be those conside...
Source: MDDI - December 13, 2018 Category: Medical Devices Authors: Omar Ford Tags: Regulatory and Compliance Implants Source Type: news

Check-Cap wins conditional IDE approval for C-Scan pilot study
Check-Cap (NSDQ:CHEK) said today it won conditional approval from the FDA for its investigational device exemption application to launch a pilot study of its C-Scan system. The Israel-based company’s C-Scan system is designed as an alternative to standard colon cancer screening methods. The system uses an ingestible, ultra-low dose X-ray capsule and a wireless tracking system to return structural information on the lumen of the colon to create 2D and 3D maps. The conditional approval will require Check-Cap to provide additional information to the FDA, but will allow the company to being enrolling patients immediately on...
Source: Mass Device - December 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Diagnostics Food & Drug Administration (FDA) Check-Cap Source Type: news

Wendy Atkin obituary
Epidemiologist whose research led to a breakthrough in bowel cancer screening programmes worldwide“Breakthrough” is an overused word when applied to medical advances. But in the case of the2010 trial of a new screening test for bowel cancer led by Wendy Atkin, professor of gastrointestinal epidemiology atImperial College London, who has died of acute myeloid leukaemia aged 71, it is fully deserved. Its impact will be felt by millions. The trial was the first in the world to show that bowel cancer – the second biggest cancer killer in the UK – could be prevented with a simple, five-minute test.The examination – wh...
Source: Guardian Unlimited Science - November 29, 2018 Category: Science Authors: Ara Darzi Tags: Cancer research Health Medical research Science Source Type: news

Many Patients With Polyps Delay Follow-up Colonoscopy: Study
MONDAY, Nov. 26, 2018 -- Many people found to have colon polyps (adenomas) that can lead to cancer don ' t have follow-up colonoscopies at recommended times, a new study finds. Patients who have certain types of adenomas, or large or numerous ones,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 26, 2018 Category: General Medicine Source Type: news

Many Patients With Polyps Delay Follow-up Colonoscopy: Study
(Source: Cancercompass News: Colorectal Cancer)
Source: Cancercompass News: Colorectal Cancer - November 26, 2018 Category: Cancer & Oncology Source Type: news

Treating a rare genetic disorder that causes colon cancer in children
(University of Houston) A University of Houston pharmaceutical scientist is developing a new drug that recycles through the colon to treat children suffering with Familial Adenomatous Polyposis, a rare genetic disorder characterized by hundreds -- if not thousands -- of colorectal polyps. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 20, 2018 Category: Cancer & Oncology Source Type: news

Artificial intelligence could help doctors identify hard-to-spot colon polyps
Colon cancer is the second leading cause of cancer-related deaths in the U.S. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 10, 2018 Category: Consumer Health News Source Type: news

How AI could help doctors identify hard-to-spot colon polyps
"Colon cancer is the second-leading cause of cancer-related deaths in the U.S. but colonoscopies have been found to reduce the risk of death from the disease by 70 percent or more by detecting cancer early. But doctors don ’t always find every polyp. As a gastroenterologist, CBS News chief medical correspondent Dr. Jon LaPook knows all too well that colon polyps can be tough to spot. But a new high-tech tool may be able to help doctors spot them. " (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 10, 2018 Category: Consumer Health News Source Type: news

Precision medicine is not enough: Moving towards precision surveillance
(Regenstrief Institute) The interval at which an individual undergoes a repeat colonoscopy because of previous pre-cancerous polyps -- a practice known as 'surveillance' -- should be tailored to the individual and not simply be determined by the results of prior colonoscopies, according to Regenstrief Institute research scientist Thomas Imperiale, M.D. In a American Journal of Gastroenterology editorial he calls for 'precision surveillance,' a phrase he has coined to echo the personalized, targeted focus of precision medicine and application of these concepts to colon cancer screening and surveillance. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 7, 2018 Category: Cancer & Oncology Source Type: news