HCV Tx-as-Prevention Strategy Seems to Work in HIV+ MSM (CME/CE)
(MedPage Today) -- Two studies examined containing HCV in this population via treatment (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 9, 2018 Category: Gastroenterology Source Type: news

FDA Panel Backs Proposed Tofacitinib Dosing for Ulcerative Colitis FDA Panel Backs Proposed Tofacitinib Dosing for Ulcerative Colitis
Pfizer scored a win in its efforts to move forward a delayed application for new use of its rheumatoid arthritis drug for treating chronic inflammation of the colon.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 9, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Text Message - Based Intervention Helps With Sobriety Maintenance
Findings among liver transplant candidates with alcoholic liver disease (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - March 9, 2018 Category: Psychiatry Tags: Gastroenterology, Psychiatry, Surgery, Journal, Source Type: news

FDA Panel Backs Higher Tofacitinib Dose in Ulcerative Colitis
(MedPage Today) -- Drugmaker seeks new indication for oral JAK inhibitor (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 8, 2018 Category: Gastroenterology Source Type: news

Renal Transplant from HCV-Positive Donors Feasible (CME/CE)
(MedPage Today) -- Small trial shows prophylactic treatment with direct-acting antivirals is key (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 8, 2018 Category: Gastroenterology Source Type: news

Fructans Suspect in Non-Celiac Gluten Sensitivity
(MedPage Today) -- Randomized double-blind trial casts doubt on need for gluten-free diets in NCGS (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 8, 2018 Category: Gastroenterology Source Type: news

Oral Oxycodone/Naloxone for Pain Control in Cirrhosis Oral Oxycodone/Naloxone for Pain Control in Cirrhosis
Management of moderate-to-severe pain in patients with cirrhosis and HCC is challenging due to the high risk of serious adverse effects. Can an oral combination of oxycodone/naloxone be used safely?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 8, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Gut Microbiome: A Therapeutic Target in Chronic Liver Disease Gut Microbiome: A Therapeutic Target in Chronic Liver Disease
This review examines the role gut microbiota play in the pathogenesis and progression of chronic liver disease. Might modulation of the gut microbiome offer novel therapeutic targets?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 8, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Gastrointestinal hormone measurably improved symptoms of non-alcoholic fatty liver disease
(University of California - San Diego) Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The findings represent an important proof-of-concept for the compound as there are currently no Food and Drug Administration-approved treatments for NAFLD and NASH. (Source: EurekAle...
Source: EurekAlert! - Medicine and Health - March 8, 2018 Category: International Medicine & Public Health Source Type: news

Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq
Mouse heart development arises from Mesp1-expressing cardiovascular progenitors (CPs) that are specified during gastrulation. The molecular processes that control early regional and lineage segregation of CPs have been unclear. We performed single-cell RNA sequencing of wild-type and Mesp1-null CPs in mice. We showed that populations of Mesp1 CPs are molecularly distinct and span the continuum between epiblast and later mesodermal cells, including hematopoietic progenitors. Single-cell transcriptome analysis of Mesp1-deficient CPs showed that Mesp1 is required for the exit from the pluripotent state and the induction of th...
Source: ScienceNOW - March 8, 2018 Category: Science Authors: Lescroart, F., Wang, X., Lin, X., Swedlund, B., Gargouri, S., Sanchez-Danes, A., Moignard, V., Dubois, C., Paulissen, C., Kinston, S., Göttgens, B., Blanpain, C. Tags: Cell Biology, Development reports Source Type: news

Gender Gap in Surgery Needs to End: General Surgery News
(MedPage Today) -- Also, location matters when it comes to incisional hernia risk after colectomy (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 7, 2018 Category: Gastroenterology Source Type: news

Stringent Diet May Suppress Gluten Neuropathy
(MedPage Today) -- Compliance with a gluten-free diet may help the pain (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 7, 2018 Category: Gastroenterology Source Type: news

Medical News Today: Natural remedies for gastritis
While there are instances where medical treatment is necessary to treat gastritis, many people find they can manage the symptoms at home. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 7, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Hikers poisoned: Veratrum steroidal alkaloid toxicity following ingestion of foraged Veratrum parviflorum - Anwar M, Turner M, Farrell N, Zomlefer WB, McDougal OM, Morgan BW.
INTRODUCTION: Steroidal alkaloids are found in plants of the genus Veratrum. Their toxicity manifests as gastrointestinal symptoms followed by a Bezold-Jarisch reflex: hypopnea, hypotension, and bradycardia. Some Veratrum steroidal alkaloids are also terat... (Source: SafetyLit)
Source: SafetyLit - March 7, 2018 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Guinea Pigs May Be Giving People Salmonella, the CDC Says
The Centers for Disease Control and Prevention (CDC) on Tuesday issued an icky warning about pet guinea pigs: they may be spreading salmonella. The CDC has identified nine people who became sick due to a strain of salmonella bacteria that can likely be traced back to contact with pet guinea pigs, according to a report from the agency. The cases affect residents of eight different states and were reported between July 2015 and December 2017. One person was hospitalized, but no deaths have been reported. Salmonella is a serious bacterial infection that results in gastrointestinal distress and can develop into a life-threaten...
Source: TIME: Health - March 6, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime public health Source Type: news

Two Docs Accused in $250M Gastric Band Insurance Scam Two Docs Accused in $250M Gastric Band Insurance Scam
The alleged scheme included forcing patients to have unneeded assessments, falsifying tests to justify bariatric surgeries, and duping payers and patients. If convicted, they could face decades in prison.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - March 6, 2018 Category: Internal Medicine Tags: Diabetes & Endocrinology News Source Type: news

OraCoat ® XyliMelts® Combat Tooth Erosion by Reducing Gastroesophageal Reflux Disease (GERD)
A Recent Study Shows that Nightly Use of Oral Adhering Discs Significantly Improves Symptoms Associated with GERDSeattle, WA (February 21, 2018) –An article about a recent clinical study, “Dental Erosion, GERD, and Salivary Stimulation,” published in theJournal of Oral& Dental Health, February2018, reports that OraCoat® XyliMelts® oral adhering discs used while sleeping reduce reflux of stomach acids, in gastroesophageal reflux disease (GERD), which causes tooth erosion. In patients with GERD, the esophagus is exposed to stomach acid long enough to cause symptoms.GERD is estimated to occur in ...
Source: Dental Technology Blog - March 6, 2018 Category: Dentistry Source Type: news

Bariatric surgery controls diabetes and obesity better than lifestyle modification
According to RCT results published inDiabetes Care, gastric bypass surgery leads to more weight loss and better diabetes management, compared to lifestyle modifications.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 6, 2018 Category: Endocrinology Source Type: news

OBV/PTV/r + Sofosbuvir With or Without RBV for HCV Gt2 or 3 OBV/PTV/r + Sofosbuvir With or Without RBV for HCV Gt2 or 3
This study investigated the efficacy and safety of 12-week OBV/PTV/r + SOF with or without RBV in patients with HCV genotype 2 or 3 infection, including those with cirrhosis.Journal of Viral Hepatitis (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 6, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Yoga vs a Low-FODMAP Diet in Patients With IBS Yoga vs a Low-FODMAP Diet in Patients With IBS
Might a yoga-based intervention or a low-FODMAP diet improve symptoms in patients with irritable bowel syndrome?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 6, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Press invitation to the 51st Annual Meeting of ESPGHAN
(Spink Health) Every year, the ESPGHAN meeting attracts the key opinion leaders in the field of paediatric gastroenterology, hepatology and nutrition from across Europe and all five continents, turning it into the largest conference of its kind worldwide. The previous congress, held in Prague, was attended by 4.700 delegates from 96 countries. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 6, 2018 Category: International Medicine & Public Health Source Type: news

Reimbursement Trends for Medical Devices in Japan
In conclusion, with the regulatory review speed by Japan’s Pharmaceuticals and Medical Devices Agency (PMDA) becoming competitive with FDA for PMA devices and the time to reimbursement being about a year after regulatory clearance with 80% of U.S. list price, Japan might be the best market, after the United States, to enter as an international market for many new companies. For 510(k) devices, the speed of reimbursement will be the same, although the speed to regulatory clearance remains a challenge. How soon a U.S. manufacturer submits the regulatory submission to PMDA is still the most substantial gap in term of co...
Source: MDDI - March 6, 2018 Category: Medical Devices Authors: Keisuke Suzuki Tags: Regulatory and Compliance Source Type: news

Clinicopathologic Factors Predict Lymph Node Metastasis in Gastric Cancer Clinicopathologic Factors Predict Lymph Node Metastasis in Gastric Cancer
T stage, lymphovascular invasion and other factors predict the likelihood of lymph node metastasis in patients with T1 gastric cancer, researchers report.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - March 5, 2018 Category: Surgery Tags: Hematology-Oncology News Source Type: news

FDA Approves PDUFA Fee Waiver for Gimoti New Drug Application
SOLANA BEACH, Calif., March 05, 2018 (GLOBE NEWSWIRE) -- Evoke Pharma, Inc. (NASDAQ:EVOK), a specialty pharmaceutical company focused on treatments for gastrointestinal (GI) d ­­iseases, today announced that the U.S. Food and Drug Administration... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 5, 2018 Category: Drugs & Pharmacology Source Type: news

PANTS: Predicting Nonresponse to Anti-TNF in Crohn's Disease PANTS: Predicting Nonresponse to Anti-TNF in Crohn's Disease
The largest prospective study of tumor necrosis factor (TNF) inhibitor therapy in Crohn's disease estimates drug response and confirms the role that pharmacokinetics and immunogenicity play.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 5, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

U.S. FDA Accepts New Drug Application for Prucalopride (SHP555) for Chronic Idiopathic Constipation
NDA acceptance of prucalopride reinforces Shire's long-standing heritage in gastrointestinal (GI) conditions and deep in-house capabilities in the category If approved, prucalopride will be the only readily available 5-HT4 agonist[1] in the U.S. for chr... Biopharmaceuticals, Gastroenterology, FDA Shire, Prucalopride, Chronic Idiopathic Constipation (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 5, 2018 Category: Pharmaceuticals Source Type: news

Boston Scientific picks up EMcision
Boston Scientific (NYSE:BSX) said today that built out its biliary offering with the acquisition of endoscope maker EMcision for an undisclosed amount. London- and Montreal-based EMcision makes the Habib EndoHPB probe, which is designed to coagulate tissue in the gastrointestinal tract in treating pancreaticobiliary cancers. Marlborough, Mass.-based Boston Scientific said the probe has 510(k) clearance from the FDA and CE Mark approval in the European Union. “As we continue to search for ways to treat pancreaticobiliary cancers, we also seek to improve the quality of life for patients living with a cancer diagno...
Source: Mass Device - March 5, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Endoscopic / Arthroscopic Mergers & Acquisitions Oncology Wall Street Beat Boston Scientific emcision Source Type: news

Medical News Today: How do you stop smelly farts?
Learn about different factors that can cause flatulence to produce a bad odor. We also look at tips for treating and preventing smelly farts. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 4, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Is GI Dynamics teasing comeback with offering?
Embattled GI Dynamics has been relatively quiet lately, but the Boston-based company recently revealed its shareholders had approved an offering worth a total of $2 million. The company held a special meeting February 27 to discuss the placement, according to a release. Could the offering help GI Dynamics continue to develop its EndoBarrier device – a technology designed to treat obesity in patients with Type 2 diabetes, that has come under fire in the past? The device works by creating a barrier between food and the wall of the small intestine and thereby changes metabolic pathways by controlling how food move...
Source: MDDI - March 2, 2018 Category: Medical Devices Authors: Omar Ford Tags: Medical Device Business Source Type: news

Mesh Bests Suture Repair for Small Umbilical Hernias Mesh Bests Suture Repair for Small Umbilical Hernias
Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - March 2, 2018 Category: Surgery Tags: Gastroenterology News Source Type: news

Polyp Risk Rises with Calcium Supplements (CME/CE)
(MedPage Today) -- Elevated with or without vitamin D3 (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 2, 2018 Category: Gastroenterology Source Type: news

Childhood Crohn's Progression Halted by Biologics (CME/CE)
(MedPage Today) -- Need for surgery still high in first years after diagnosis (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 2, 2018 Category: Gastroenterology Source Type: news

Medical News Today: Why do I have muscle spasms in my stomach?
Stomach spasms occur when muscles in the stomach or intestines contract. We look at 10 common causes of muscles spasms, as well as spasms during pregnancy. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 2, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Laparoscopic Intragastric Resection Laparoscopic Intragastric Resection
Read about this novel technique that may provide a safe and effective minimally invasive approach to gastric submucosal tumors.Annals of Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 2, 2018 Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news

Gastric bypass surgery can give better control for diabetes and obesity than lifestyle modification
(Brigham and Women's Hospital) Patients treated with a form of bariatric surgery did significantly better than patients provided with an intensive diabetes and weight management program. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 2, 2018 Category: International Medicine & Public Health Source Type: news

Calcium Supplements Up Risk for Precancerous Serrated Polyps Calcium Supplements Up Risk for Precancerous Serrated Polyps
Rather than reducing risk, a randomized chemoprevention trial of calcium and vitamin D supplementation showed an increased risk for serrated sessile adenomas or polyps during follow-up.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 2, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Cardiac monitor dev Eko raises $5m in Series A
Cardiac device developer Eko said yesterday it raised $5 million in a Series A round to help support its platform designed for valvular heart disease screening and heart failure monitoring. The round was led by Artis Ventures and joined by Strategic Partners, DreamIt Ventures, 1812 Ventures and Founder.org, the San Francisco-based company said. “Eko and Artis Ventures are of likemind in that we both want to tackle the use of technology to improve people’s lives, and for the longest time we’ve relied on the ability for a trained ear to diagnose heart problems. By elegantly applying machine learning to the ...
Source: Mass Device - March 1, 2018 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Cardiovascular Diagnostics eko Source Type: news

Vedolizumab Relieves Refractory Crohn's Disease Vedolizumab Relieves Refractory Crohn's Disease
The monoclonal antibody helps some patients with Crohn's disease, according to the VERSIFY study, which builds on findings from the GEMINI 2 and 3 trials.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 1, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

12 People Got Worms from Eating Raw Wild Boar at a Party
Twelve people developed the parasitic infection trichinellosis after eating raw wild boar at a party in California, according to a new report from the Centers for Disease Control and Prevention (CDC). Humans and animals typically develop trichinellosis after eating raw or undercooked meat that contains Trichinella worm larvae, according to the CDC. The worms are released into the small intestine after consumption, where they mature and lay eggs. Eventually, those eggs hatch into immature worms and reach the arteries and muscles. The infection spreads when a human or animal eats meat from an animal with larvae already in it...
Source: TIME: Health - March 1, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime onetime public health Source Type: news

Diet - Treated Chronic Illness May Lead to Disordered Eating
In most studies examined, diet - treated chronic illness preceded disordered eating in children (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - March 1, 2018 Category: Psychiatry Tags: Endocrinology, Family Medicine, Gastroenterology, Nursing, Pediatrics, Psychiatry, Pulmonology, Journal, Source Type: news

A Stool Management System for Fecal Incontinence Patients A Stool Management System for Fecal Incontinence Patients
A new study evaluates the safety and efficacy of a stool management system designed to manage fecal incontinence in bedridden patients.Wounds (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

First- and Second-line Therapy for Moderate-severe UC First- and Second-line Therapy for Moderate-severe UC
This study assessed the comparative efficacy and safety of different therapies as first-line and second-line agents for moderate-severe ulcerative colitis. What is the optimal regimen?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Diagnostic Performance of Noninvasive Fibrosis Tests in NAFLD Diagnostic Performance of Noninvasive Fibrosis Tests in NAFLD
What factors may impact the diagnostic performance of noninvasive fibrosis tests in patients with nonalcoholic fatty liver disease? Does accuracy differ across various NAFLD subgroups?Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 1, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Medical News Today: Why am I vomiting green or yellow bile?
Throwing up bile, a yellow or greenish liquid, can happen for many reasons. Some of the causes may be serious and require urgent medical attention. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 28, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

PPIs and CV Safety: Good Science to the Rescue PPIs and CV Safety: Good Science to the Rescue
Amid the controversy, Dr David Johnson reviews new research supporting the cardiovascular safety of PPIs.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 28, 2018 Category: Consumer Health News Tags: Gastroenterology Viewpoint Source Type: news

What Are Adaptogens and Why Are People Taking Them?
Adaptogens are a buzzword in the wellness world, popping up everywhere from juice bars to lifestyle blogs. But what are adaptogenic herbs, exactly? Here’s what you need to know. What are adaptogens? Adaptogens are non-toxic plants that are marketed as helping the body resist stressors of all kinds, whether physical, chemical or biological. These herbs and roots have been used for centuries in Chinese and Ayurvedic healing traditions, but they’re having a renaissance today. Some, like holy basil, can be eaten as part of a meal, and some are consumed as supplements or brewed into teas. Each one claims to do somet...
Source: TIME: Health - February 28, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition healthytime onetime Source Type: news

New graphene laser technique opens door for edible electronics
(American Chemical Society) Electronics, the lifeblood of the modern world, could soon be part of our daily diet. In a study appearing in ACS Nano, scientists report that they have developed a way to write graphene patterns onto virtually any surface including food. They say the new technique could lay the groundwork for the edible electronics capable of tracing the progression of foods from farm to table, as well as detecting harmful organisms that can cause gastric distress. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 28, 2018 Category: Biology Source Type: news

Morris animal foundation awards $1 million for new studies benefiting canine health
(Morris Animal Foundation) For the good of dogs everywhere, Morris Animal Foundation announced it awarded nearly $1 million in grants for 11 canine research projects. The studies will help veterinary scientists improve the health and well-being of dogs suffering from deadly and debilitating diseases, including cancer, spinal cord disease and gastrointestinal disorders. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 28, 2018 Category: International Medicine & Public Health Source Type: news

Early Studies Often Show Exaggerated Treatment Effect
Findings based on assessment of trials evaluating drugs, devices to treat chronic medical conditions (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - February 28, 2018 Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news