3-MCPD exposure enhances ovarian fibrosis and reduces oocyte quality in mice
Environ Pollut. 2022 Nov 14:120662. doi: 10.1016/j.envpol.2022.120662. Online ahead of print.ABSTRACT3-monochloro-1,2-propanediol (3-MCPD) is a food contaminant believed to be harmful to human health. Previous studies showed that 3-MCPD exerts toxic effects in multiple tissues, but whether 3-MCPD affects female reproductive function remained unknown. Here, using mouse gastric lavage models, we report that 3-MCPD exposure for four weeks affected body growth, decreased the ovary/body weight ratio, and increased atretic follicle numbers. Expression levels of follicular development-related factors decreased. Further studies fo...
Source: Environmental Pollution - November 17, 2022 Category: Environmental Health Authors: Quan-Kuo He Yan-Ping Li Zhi-Ran Xu Wen-Bo Wei Feng-Xin Qiao Ming-Xin Sun Yue-Cen Liu Yan-Zhu Chen Hai-Long Wang Zhong-Quan Qi Yu Liu Source Type: research
An extremely rare case of endophthalmitis in an infant with congenital tuberculosis
Paediatr Int Child Health. 2022 Oct 25:1-5. doi: 10.1080/20469047.2022.2129193. Online ahead of print.ABSTRACTCongenital tuberculosis (CTB) is the transmission of Mycobacterium tuberculosis infection from mother to infant during the intrauterine period or delivery. An 82-day-old infant presented to Nilratan Sircar Medical College and Hospital, Kolkata, with a history of persistent fever from Day 15 of age. Over the course of more than 2 months, there were pneumonia, hepatosplenomegaly and endophthalmitis which were unresponsive to a range of antibiotics, and there had been several admissions to local hospitals. On this adm...
Source: Paediatrics and international child health - October 25, 2022 Category: Pediatrics Authors: Kakali Roy Bageshree Saha Sandipan Sen Nivedita Manna Shreyanshi Biswas Tania Roy Tilling Tani Bakul Sarkar Tapan Kumar SinhaMahapatra Source Type: research
