Outcomes of omental patch repair in large or giant perforated peptic ulcer are comparable to gastrectomy
AbstractPurposePerforated peptic ulcer (PPU) complicates 2 to 10% of patients with peptic ulcer disease and has mortality risk of up to 20%. Omental patch repair is the mainstay of surgical management and gastric resectional procedures are advocated for a large/giant ulcer or suspected malignancy. Emergency gastrectomy is associated with increased morbidity and mortality. The aim of this study is to compare the outcomes of omental patch repair with gastrectomy in patients with large PPU ( ≥ 20 mm).MethodsA retrospective review of all PPU patients who underwent surgery from January 2008 to December 2014 was d...
Source: European Journal of Trauma and Emergency Surgery - October 14, 2019 Category: Emergency Medicine Source Type: research

The Use of the Overstitch for Bariatric Weight Loss
Obesity is a public health pandemic and leading contributor to morbidity and mortality. Endoscopic bariatric therapies have emerged as a viable minimally invasive treatment option to fill the therapeutic gap between conservative and surgical approaches. The ability to reliably place full-thickness sutures throughout the gastrointestinal tract has opened the door to novel endoscopic gastric restrictive procedures. A growing body of literature supports endoscopic sleeve gastroplasty as a safe, effective, and reproducible endoscopic treatment of obesity and metabolic syndrome. In addition, endoscopic sutured revision procedur...
Source: Gastrointestinal Endoscopy Clinics of North America - October 14, 2019 Category: Gastroenterology Authors: Rabindra R. Watson Source Type: research

Nomogram to predict prolonged postoperative ileus after gastrectomy in gastric cancer.
CONCLUSION: We have developed a prediction nomogram of PPOI for gastric cancer. This novel nomogram might serve as an essential early warning sign of PPOI in gastric cancer patients. PMID: 31636476 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - October 14, 2019 Category: Gastroenterology Authors: Liang WQ, Zhang KC, Cui JX, Xi HQ, Cai AZ, Li JY, Liu YH, Liu J, Zhang W, Wang PP, Wei B, Chen L Tags: World J Gastroenterol Source Type: research

Concurrent bariatric surgery and surgical resection of massive localized lymphedema of the thigh. A case report
ConclusionMLL remains to be underdiagnosed. Due to the obesity epidemic, clinicians must be aware of this once rare disease. The role of concurrent bariatric surgery with surgical resection of MLL warrants further studies. (Source: Annals of Medicine and Surgery)
Source: Annals of Medicine and Surgery - October 12, 2019 Category: General Medicine Source Type: research

Long-limb Roux-en-Y Reconstruction after Subtotal Gastrectomy to Treat Severe Diabetic Gastroparesis.
We report a case of a 37-year-old man with a history of recurrent episodes of vomiting and long-standing type 2 diabetes mellitus. Esophagogastroduodenoscopy did not reveal any findings of reflux esophagitis or obstructive lesions. A gastric emptying time scan showed prolonged gastric emptying half-time (344 minutes) indicating delayed gastric emptying. Laboratory tests revealed elevated fasting serum glucose and glycosylated hemoglobin (HbA1c, 12.9%) and normal fasting C-peptide and insulin levels. We performed Roux-en-Y reconstruction after subtotal gastrectomy to treat gastroparesis and improve glycemic control, and the...
Source: Journal of Gastric Cancer - October 12, 2019 Category: Gastroenterology Tags: J Gastric Cancer Source Type: research

Modified Book Binding Technique (MBBT) for Intracorporeal Gastroduodenostomy in Totally Laparoscopic Distal Gastrectomy: Initial Experience.
This study evaluated the safety and feasibility of MBBT in patients undergoing TLDG. Thirty-three patients who underwent TLDG with MBBT were retrospectively evaluated. The mean operation time was 277.6±37.1 minutes, including 51.9±15.7 minutes for reconstruction. Two patients had anastomosis-related complications, one patient with stricture after leakage and 1 patient with stenosis. The former patient was treated with endoscopic balloon dilatation, and the latter was managed conservatively; neither required re-operation. MBBT is a safe and feasible technique, with acceptable surgical outcomes. It may be a goo...
Source: Journal of Gastric Cancer - October 12, 2019 Category: Gastroenterology Tags: J Gastric Cancer Source Type: research

Esophagojejunal Anastomosis after Laparoscopic Total Gastrectomy for Gastric Cancer: Circular versus Linear Stapling.
Conclusions: The overlap method was superior to the HDST with respect to anastomotic complications, especially anastomosis stricture. PMID: 31598376 [PubMed] (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - October 12, 2019 Category: Gastroenterology Tags: J Gastric Cancer Source Type: research

A Novel Technique of Hand-Sewn Purse-String Suturing by Double Ligation Method (DLM) for Intracorporeal Circular Esophagojejunostomy.
Conclusions: Our procedure for hand-sewn purse-string suturing with the double ligation method is simple and safe. PMID: 31598372 [PubMed] (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - October 12, 2019 Category: Gastroenterology Tags: J Gastric Cancer Source Type: research

Bioelectrical Impedance Analysis for Prediction of Early Complications after Gastrectomy in Elderly Patients with Gastric Cancer: the Phase Angle Measured Using Bioelectrical Impedance Analysis.
Conclusions: Our findings show that preoperative low phase angle predicts the risk of overall and severe complications. Our findings suggest that BIA should be performed to assess the risk of postoperative complications in elderly patients with gastric cancer. PMID: 31598371 [PubMed] (Source: Journal of Gastric Cancer)
Source: Journal of Gastric Cancer - October 12, 2019 Category: Gastroenterology Tags: J Gastric Cancer Source Type: research

Advances in the treatment of gastric cancer: 2019
Purpose of review The aim of this study was to review studies published within the past year regarding management of gastric cancer. Recent findings Laparoscopic gastrectomy achieves equivalent survival compared with open gastrectomy in early stage and locally advanced gastric cancer. Adjuvant chemotherapy with 6 months of S-1 and oxaliplatin was superior to 12 months of S-1, and the addition of postoperative radiation therapy did not improve survival. The FLOT regimen is the new standard for preoperative chemotherapy. In metastatic gastric cancer, the addition of docetaxel to S-1 and cisplatin failed to improve overa...
Source: Current Opinion in Gastroenterology - October 12, 2019 Category: Gastroenterology Tags: STOMACH AND DUODENUM: Edited by Mitchell L. Schubert Source Type: research

Comparison of Billroth  I, Billroth II, and Roux-en-Y Reconstruction After Totally Laparoscopic Distal Gastrectomy: A Randomized Controlled Study
This study aimed to explore the efficacy of delta-shaped Billroth  I anastomosis in totally laparoscopic distal gastrectomy for digestive tract reconstruction, and provide clinical data for determining the most appropriate digestive tract reconstruction method after distal gastrectomy.MethodsThis was a prospective randomized controlled study. A total of 180 patients were randomly and prospectively selected from Renmin Hospital of Wuhan University by random number table. These patients were randomly divided into three groups: Billroth  I group, Billroth II group, and Roux-en-Y (RY) group.ResultsThere were sig...
Source: Advances in Therapy - October 12, 2019 Category: Drugs & Pharmacology Source Type: research

A Comparison of the Effects of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy on Body Mass Composition as Measured by Air Displacement Plethysmography
ConclusionThe LSG and RYGB both impart dramatic meaningful loss in excess body weight. In addition, both the LSG and RYGB impart dramatic reductions in fat mass. However, both procedures induce loss of lean mass and there appears to be no difference between the two procedures in this regard despite their anatomic and physiologic differences. (Source: Obesity Surgery)
Source: Obesity Surgery - October 12, 2019 Category: Surgery Source Type: research

Enormous gastric gastrointestinal stromal tumor causing weight loss and anemia in an elderly female; case report
ConclusionGISTs most commonly affects the stomach, most tumors are treated by primary surgical excision with normal safety margins, advanced disease may need imatinib before surgery which helps in decreasing the size of the tumor and makes surgery easier. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - October 11, 2019 Category: Surgery Source Type: research

Physical Activity Patterns Among Individuals Before and Soon After Bariatric Surgery
This study aims to assess MVPA changes during the rapid weight loss phase through self-reporting and objective measures.MethodsPhysical activity patterns were assessed as minutes per day spent doing MVPA. A walking cadence of ≥ 100 steps per minute defined MVPA. Individuals completing gastric bypass (N = 7) and sleeve gastrectomy (N = 17) procedures (21 females, 3 males, age 42.2 ± 12.6 years, body mass 121.8 ± 24.8 kg, BMI 44.0 ± 6.5) completed office visits at 12 ± 6 days pre- and 35&th...
Source: Obesity Surgery - October 11, 2019 Category: Surgery Source Type: research

Laparoscopic sleeve gastrectomy induces sustained changes in gray and white matter brain volumes and resting functional connectivity in obese patients
Obesity is associated with decreased brain gray- (GM)/white-matter (WM) volumes in regions. Laparoscopic-sleeve-gastrectomy (LSG) is an effective bariatric surgery associated with neuroplastic changes in patients with obesity at 1-month-post-LSG. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - October 11, 2019 Category: Surgery Authors: Yuanyuan Wang, Gang Ji, Yang Hu, Guanya Li, Yueyan Ding, Chunxin Hu, Lei Liu, Wenchao Zhang, Karen M. von Deneen, Yu Han, Guangbin Cui, Huaning Wang, Peter Manza, Nora D. Volkow, Yongzhan Nie, Gene-Jack Wang, Yi Zhang Tags: Original articles Source Type: research

Comment on: “Perioperative outcomes of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in super-obese and super-super-obese patients: a national database analysis”
We have read with great interest this study (1) analyzing the perioperative outcomes of Roux-en Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in super-obese patients (SO, body mass index (BMI) 50 - 59.9 kg/m2) and super-super obese patients (SSO, BMI ≥ 60 kg/m2). The authors investigated the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database and 356,621 patients met the inclusion criteria. Of these, 255,459 (71.6%) underwent SG and 101,162 (28.4%) underwent RYGB. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - October 11, 2019 Category: Surgery Authors: Adrian T. Billeter, Beat P. M üller-Stich Source Type: research

Comment on: perioperative outcomes of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in super-obese and super-super-obese patients: a national database analysis
We have read with great interest this study [1] analyzing the perioperative outcomes of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in super-obese patients (SO; body mass index [BMI] 50 –59.9 kg/m2) and super-super-obese patients (SSO; BMI ≥60 kg/m2). The authors investigated the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database, and 356,621 patients met the inclusion criteria. Of these, 255,459 (71.6%) underwent SG and 101,162 (28.4%) under went RYGB. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - October 11, 2019 Category: Surgery Authors: Adrian T. Billeter, Beat P. M üller-Stich Tags: Editorial comment Source Type: research

Laparoscopic sleeve gastrectomy induces sustained changes in gray and white matter brain volumes and resting functional connectivity in obese patients.
Abstract BACKGROUND: Obesity is associated with decreased brain gray- (GM) and white-matter (WM) volumes in regions. Laparoscopic sleeve gastrectomy (LSG) is an effective bariatric surgery associated with neuroplastic changes in patients with obesity at 1 month postLSG. OBJECTIVE: To investigate whether LSG can induce sustained neuroplastic recovery of brain structural abnormalities, and whether structural changes are accompanied by functional alterations. SETTING: University hospital, longitudinal study. METHODS: Structural magnetic resonance imaging and voxel-based morphometry analysis were employ...
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - October 11, 2019 Category: Surgery Authors: Wang Y, Ji G, Hu Y, Li G, Ding Y, Hu C, Liu L, Zhang W, von Deneen KM, Han Y, Cui G, Wang H, Manza P, Volkow ND, Nie Y, Wang GJ, Zhang Y Tags: Surg Obes Relat Dis Source Type: research

Comment on: perioperative outcomes of laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy in super-obese and super-super-obese patients: a national database analysis.
BP PMID: 31676162 [PubMed - as supplied by publisher] (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - October 11, 2019 Category: Surgery Authors: Billeter AT, Müller-Stich BP Tags: Surg Obes Relat Dis Source Type: research

Sleeve plus procedures: need of time
AbstractLaparoscopic sleeve gastrectomy as a standalone procedure has gained a lot of popularity over laparoscopic Roux-en-Y gastric bypass in the last decades and is the most frequently performed bariatric procedure worldwide; however, the long-term results are not promising in terms of weight regain and re-emergence of comorbidities. Considering the proven concept of biliopancreatic diversion with duodenal switch, many novel procedures have been developed involving a sleeve gastrectomy along with some intestinal bypass or alteration in small intestine anatomy. These procedures show better technical feasibility and are as...
Source: Surgery Today - October 10, 2019 Category: Surgery Source Type: research

The Combined Use of Drainage Amylase Concentration and Serum C-reactive Protein as Predictors of Pancreas-Related Complications after Elective Gastrectomy.
CONCLUSIONS: Splenectomy correlates with PPRC, which is consistent with results from large clinical trials. A combined use of dAmy3 and sCRP3 can be useful in predicting the risks of PPRC. PMID: 31600759 [PubMed - as supplied by publisher] (Source: Oncology)
Source: Oncology - October 10, 2019 Category: Cancer & Oncology Authors: Wakahara T, Kanemitsu K, Asari S, Tsuchida S, Ueno N, Toyokawa A, Sasako M Tags: Oncology Source Type: research

Survival benefit of palliative gastrectomy followed by chemotherapy in stage IV gastric signet ring cell carcinoma patients: A large population ‐based study
This study aimed to evaluate survival benefit of palliative gastrectomy plus chemotherapy (PG+C) for metastatic gastric SRCC.MethodsWe obtained data on gastric cancer patients between 2010 and 2015 from the Surveillance, Epidemiology, and End Results (SEER) database. Statistical methods includedχ2 tests, Kaplan ‐Meier curves, COX models, propensity score matching (PSM) and subgroup analysis.ResultsAmong 27  240 gastric cancer patients included, 4638 (17.03%) were SRCC patients. The proportion of patients with younger age, female gender, poorly differentiated grade and M1 stage was higher in SRCC than in NOS (P 
Source: Cancer Medicine - October 10, 2019 Category: Cancer & Oncology Authors: Tao Shi, Xueru Song, Qin Liu, Yang Yang, Lixia Yu, Baorui Liu, Jia Wei Tags: ORIGINAL RESEARCH Source Type: research

Single Purse-String Suture for Reinforcement of Duodenal Stump During Laparoscopic Radical Gastrectomy for Gastric Cancer
Conclusion: Reinforcement on duodenal stump using laparoscopic single purse-string suture during laparoscopic radical gastrectomy is simple and effective and could avoid the incidence of duodenal stump leakage to some extent. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - October 9, 2019 Category: Cancer & Oncology Source Type: research

Preventive effect on delayed gastric emptying of preserving the infra-pyloric vein in laparoscopic pylorus-preserving gastrectomy for early gastric cancer
ConclusionRegarding LRPPG, preserving the IPV did not help prevent DGE and resulted in no significant difference in the outcomes. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - October 9, 2019 Category: Surgery Source Type: research

Perioperative Outcomes of Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in Patients with Diabetes Mellitus: an Analysis of the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) Database
AbstractBackgroundThe safety and efficacy of laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) to treat obesity and associated comorbidities, including diabetes mellitus, is well established. As diabetes may add risk to the perioperative period, we sought to characterize perioperative outcomes of these surgical procedures in diabetic patients.MethodsUsing the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database, we identified patients who underwent LSG and LRYGB between 2015 and 2017, grouping by non-diabetics (NDM), non-insulin-dependent dia...
Source: Obesity Surgery - October 9, 2019 Category: Surgery Source Type: research

Effects of depth of neuromuscular block on postoperative pain during laparoscopic gastrectomy: A randomised controlled trial
BACKGROUND Evidence on whether the use of deep neuromuscular block (NMB) influences postoperative pain after laparoscopic surgery is limited, and existing studies have shown conflicting results. We studied the effect of the depth of NMB during laparoscopic gastrectomy on postoperative pain. OBJECTIVE The aim of this study was to evaluate the effect of depth of NMB during laparoscopic gastrectomy on postoperative pain by allocating patients randomly to either deep or moderate NMB with a standard-pressure pneumoperitoneum. DESIGN A randomised, controlled, double-blind study. SETTING A university-affiliated hospita...
Source: European Journal of Anaesthesiology - October 8, 2019 Category: Anesthesiology Tags: Postoperative pain Source Type: research

Expression Profile of Markers for Targeted Therapy in Gastric Cancer Patients: HER-2, Microsatellite Instability and PD-L1
ConclusionsGC patients who exhibited markers that can serve as an indication for known targeted therapy represent 40.4% of cases. The IT group was associated with a better prognosis. No benefit with standard adjuvant treatment appears to be achieved in MSI/PD-L1+ GCs. (Source: Molecular Diagnosis and Therapy)
Source: Molecular Diagnosis and Therapy - October 8, 2019 Category: Molecular Biology Source Type: research

Short-term outcomes of single-port versus conventional laparoscopic sleeve gastrectomy: a propensity score matched analysis
AbstractBackgroundSleeve gastrectomy (SG) has become a frequent bariatric procedure. Single-port sleeve gastrectomy (SPSG) could reduce parietal aggression however its development has been restrained due to fear of a complex procedure leading to increased morbidity and suboptimal sleeve construction. The aim of this study was to compare the short-term outcomes of SPSG versus conventional laparoscopic sleeve gastrectomy (CLSG) with regards to morbidity, weight loss, and co-morbidity resolution.MethodsBetween January 2015 and December 2016, data from all consecutive patients that underwent SPSG and CLSG in two institutions p...
Source: Surgical Endoscopy - October 8, 2019 Category: Surgery Source Type: research

Concurrent Magnetic Sphincter Augmentation and Hiatal Hernia Repair for Refractory GERD Following Laparoscopic Sleeve Gastrectomy
Gastroesophageal reflux disease (GERD) has a reported incidence of between 10 to 20% in western populations with an even higher incidence in populations with obesity (1). The vast majority of patients are managed medically with surgical intervention undertaken in those with recalcitrant GERD. Populations with obesity and recalcitrant GERD who are interested in weight loss surgery have historically undergone Laparoscopic Roux En Y Gastric Bypass (LRYGB). De Goot et al in their 2009 meta-analysis demonstrated improvement in GERD in people with obesity following LRYGB(2). (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - October 8, 2019 Category: Surgery Authors: Gordian U. Ndubizu, Anthony T. Petrick, Ryan Horsley Source Type: research

Concurrent magnetic sphincter augmentation and hiatal hernia repair for refractory GERD after laparoscopic sleeve gastrectomy
Gastroesophageal reflux disease (GERD) has a reported incidence of between 10% and 20% in Western populations with an even higher incidence in populations with obesity [1]. The vast majority of patients are managed medically with surgical intervention undertaken in those with recalcitrant GERD. Populations with obesity and recalcitrant GERD who are interested in weight loss surgery have historically undergone laparoscopic Roux-en-Y gastric bypass (LRYGB). De Goot et  al. [2], in their 2009 meta-analysis, demonstrated improvement in GERD in people with obesity after LRYGB. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - October 8, 2019 Category: Surgery Authors: Gordian U. Ndubizu, Anthony T. Petrick, Ryan Horsley Tags: Video case report Source Type: research

Laparoscopic versus open subtotal gastrectomy for adenocarcinoma of the stomach in a Western population: peri-operative and 5-year oncological outcomes
This study compares the peri-operative and long-term oncological outcomes for laparoscopic subtotal gastrectomy (LSG) versus open subtotal gastrectomy (OSG) for adenocarcinoma of the stomach in a Western population.MethodsA retrospective, intention-to-treat analysis study was conducted for consecutive patients undergoing gastrectomy with curative intent for adenocarcinoma of the stomach between November 2006 and October 2016. Univariate analysis was used to compare peri-operative outcomes between LSG and OSG. Logistic regression with bootstrapping validation was used to identify independent risk factors for predicting 2-ye...
Source: Surgical Endoscopy - October 7, 2019 Category: Surgery Source Type: research

Postoperative Long-Term Outcomes in Elderly Patients with Gastric Cancer and Risk Factors for Death from Other Diseases
AbstractBackgroundElderly patients with gastric cancer are frequently treated surgically in current clinical practice. Although several studies have investigated short-term outcomes after gastrectomy in elderly patients, most did not evaluate long-term outcomes.MethodsWe analyzed 1154 consecutive patients who underwent curative gastrectomy for gastric cancer between 2001 and 2013. We classified them into two groups: the elderly group (n = 241), consisting of patients aged ≥75 years, and the non-elderly group (n = 913), consisting of patients aged
Source: World Journal of Surgery - October 4, 2019 Category: Surgery Source Type: research

Esophagitis After Bariatric Surgery: Large Cross-sectional Assessment of an Endoscopic Database
ConclusionEE is more prevalent after SG compared with RYGB in a pre-bariatric surgery cohort with GERD. SG is associated with significant esophageal physiologic changes conducive to GERD and its clinical consequences. (Source: Obesity Surgery)
Source: Obesity Surgery - October 4, 2019 Category: Surgery Source Type: research

Successful biliary self ‐expandable metallic stenting using an ultra‐slim endoscope for cholangitis caused by pancreatic cancer
AbstractAn 80 ‐year‐old man who had a 10×50‐mm self‐expandable metallic stent (SEMS) (BONA‐SHIMSTENT biliary‐covered; Standard SciTech Inc, Seoul, South Korea) placed for biliary obstruction due to pancreatic cancer presented with fever and jaundice. He previously underwent distal gastrectomy with Bi llroth II reconstruction for duodenal ulcer. (Source: Journal of Hepato-Biliary-Pancreatic Sciences)
Source: Journal of Hepato-Biliary-Pancreatic Sciences - October 4, 2019 Category: Gastroenterology Authors: Akihiko Kida, Koichiro Matsuda, Masaaki Yano, Fumitaka Arihara, Kohei Ogawa, Mitsuru Matsuda, Akito Sakai Tags: How I Do It Source Type: research

Challenges and new directions in obesity management: lifestyle modification programmes, pharmacotherapy and bariatric surgery.
This article aims to discuss challenges faced by health-care providers when managing patients with obesity and to highlight sustainable policies in clinical practice and future research. All health professionals dealing with obesity should consider lifestyle-modification programmes within a multidisciplinary setting as the key element of weight management. However, standardisation is needed in terms of nature, content and duration of these programmes in order to facilitate their implementation in clinical practice at different levels. Moreover, health professionals should be aware that these programmes, for patients indica...
Source: Journal of Population Therapeutics and Clinical Pharmacology - October 3, 2019 Category: Drugs & Pharmacology Tags: J Popul Ther Clin Pharmacol Source Type: research

Recent Status of Laparoscopic Distal Gastrectomy in Korea: A Multicenter Retrospective Cohort Study (Pre-study Survey of KLASS-07 Trial)
Purpose: To analyze the surgical trend and brief postoperative results of laparoscopic distal gastrectomy (LDG) in Korea on the basis of a multicenter cohort.Materials and Methods: Data of 812 patients who underwent LDG between January and December 2016 were collected from 14 surgeons at 7 institutions. Patients were divided into laparoscopy-assisted distal gastrectomy (LADG) group and totally laparoscopic distal gastrectomy (TLDG) group. Perioperative and clinicopathologic outcomes were compared retrospectively.Results: Among the patients [n = 222 (27.3%) LADG; n = 590 (72.7%) TLDG], there are no significant differences i...
Source: Frontiers in Oncology - October 3, 2019 Category: Cancer & Oncology Source Type: research

Clinical, Endoscopic, and Histologic Findings at the Distal Esophagus and Stomach Before and Late (10.5  Years) After Laparoscopic Sleeve Gastrectomy: Results of a Prospective Study with 93% Follow-Up
ConclusionsPatients submitted to LSG showed a significant and progressive increase in the presence of “de novo” GERD. Also, an increased duodenogastric reflux was seen through an open and immobile pylorus. Therefore, based on these results, it seems like LSG is a “pro-reflux” surgical procedure, which should be continuously evaluated late after surgery. (Source: Obesity Surgery)
Source: Obesity Surgery - October 3, 2019 Category: Surgery Source Type: research

The Relationship Between Histopathologic Findings and Weight Loss in Laparoscopic Sleeve Gastrectomy
ConclusionsA correlation of histopathologic changes in morbid obese patients with weight loss after bariatric surgery was asserted in this study. Operating on younger patients with lower BMI and inactive gastritis with the LSG method could contribute to achieving more successful results. Prospective research studies are necessary within this context. (Source: Obesity Surgery)
Source: Obesity Surgery - October 3, 2019 Category: Surgery Source Type: research

M énétrier's disease : a case of successful treatment using long-acting octreotide.
Ménétrier's disease : a case of successful treatment using long-acting octreotide. Acta Gastroenterol Belg. 2019 Jul-Sep;82(3):429-432 Authors: Nunes G, Barosa R, Patita M, Pinto-Marques P, Gonçalves D, Fonseca C, Alves de Matos A, Fonseca J Abstract The authors describe a 31 years old male, admitted for hematemesis, epigastric pain and lower limb edema. Laboratorial data showed haemoglobin 18.4g/dl, total proteins 2.8g/dl, albumin 1.6g/dl and hipogammaglobulinaemia. 24h urinary proteins were normal. HIV and CMV serology were negative. Upper GI endoscopy revealed markedly enlarged ...
Source: Acta Gastro-Enterologica Belgica - October 2, 2019 Category: Gastroenterology Tags: Acta Gastroenterol Belg Source Type: research

Minimally Invasive and Robotic Surgery in the Surgical Treatment of Esophagogastric Junction Cancer
Publication date: Available online 1 October 2019Source: Cirugía Española (English Edition)Author(s): Ismael Díez del Val, Carlos Loureiro González, José Ignacio Asensio Gallego, Carla Bettonica Larrañaga, Saioa Leturio Fernández, Emma Eizaguirre Letamendia, Mónica Miró Martín, Marta María García Fernández, Laura Martí Gelonch, Humberto Aranda Danso, Julen Barrenetxea Asua, Fernando Estremiana García, Javier Ortiz Lacorzana, Leandre Farran TeixidóAbstractMinimally invasive surgery provides for the treatment of es...
Source: Cirugia Espanola - October 1, 2019 Category: Surgery Source Type: research

Large tumor size is a poor prognostic factor of gastric cancer with signet ring cell: Results from the surveillance, epidemiology, and end results database
There has been a steady increase in the incidence of signet ring cell (SRC) carcinoma, a distinct histological type with cells containing abundant intracytoplasmic mucin. We aimed to analyze the clinicopathological characteristics and prognostic value of patients with SRC gastric cancer (GC) who underwent gastrectomy. Clinical data of 10,312 GC patients who underwent D2 radical gastrectomy were obtained from the Surveillance, Epidemiology, and End Results database and were retrospectively analyzed. X-tile plots were constructed to illustrate the optimal cut-off points using the minimum P-value from the log-rank Chi-square...
Source: Medicine - October 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Comparison of the Effects of Epidural Analgesia and Patient-controlled Intravenous Analgesia on Postoperative Pain Relief and Recovery After Laparoscopic Gastrectomy for Gastric Cancer
In this study, the effects of EDA and patient-controlled intravenous analgesia (PCIA) after laparoscopic distal gastrectomy (LDG) were compared. Methods: This was a retrospective study that included 82 patients undergoing LDG for gastric cancer. Patients received either EDA (n=67) or PCIA (n=15) for postoperative pain relief. Postoperative outcomes and analgesia-related adverse events were compared between the two modalities. Results: EDA and PCIA patients showed no differences in the incidence of complications [9 (13%) vs. 2 (13%); P=0.99] and the length of postoperative hospital stay (9.6±4.5 d vs. 9....
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - October 1, 2019 Category: Surgery Tags: Original Articles Source Type: research

Gastric emptying scintigraphy results may influence the selection of the type of bariatric surgery: A cohort study
Bariatric surgery (BAS) may result in adverse outcomes that include appearance of gastrointestinal (GI) symptoms and/or failure to reach the weight reduction goal. This retrospective study tested the hypothesis that pre-operative gastric emptying (GE) abnormality is responsible for adverse post-surgical outcomes. Pre-operative GE was performed using the standard solid-meal GE scintigraphy (GES) in 111 consecutive patients (105 females and 6 males, mean age 46.2 years, range 20–70 years) who were evaluated for BAS. All underwent BAS – 93 had laparoscopic sleeve gastrectomy (LSG) and 18 had Roux-en-Y (ReY) gastr...
Source: Medicine - October 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

The investigation of diet recovery after distal gastrectomy
This study aims to investigate the adaptation process of the alimentary tract after distal gastrectomy and understand the impact of remnant stomach volume (RSV) on diet recovery. One year after gastrectomy, although patients’ oral intake had increased, the RSV was decreased and small bowel motility was enhanced. Patients with a larger RSV showed no additional benefits regarding nutritional outcomes. We prospectively enrolled patients who underwent distal gastrectomy with Billroth II reconstruction to treat gastric cancer at a tertiary hospital cancer center between September 2009 and February 2012. Demographic data...
Source: Medicine - October 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

1071PDTreatment outcome for Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma
ConclusionsA substantial proportion of patients withH.pylori-negative gastric MALT lymphoma remain antibiotic-responsive and can be cured using radiotherapy and chemotherapy.Legal entity responsible for the studyThe authors.FundingHas not received any funding.DisclosureAll authors have declared no conflicts of interest. (Source: Annals of Oncology)
Source: Annals of Oncology - October 1, 2019 Category: Cancer & Oncology Source Type: research

1070PDTreatment outcomes and pattern of failure in primary gastric diffuse large B cell lymphoma with complete remission following R-CHOP chemotherapy
ConclusionsThe main pattern of initial failure is LRF, especially in the stomach in patients with primary gastric DLBCL. Gastric local treatment such as consolidation RT can effectively prevent gastric failure. Therefore, gastric local treatment should be considered for patients at high risk of LRF, such as multiple gastric lesions.Legal entity responsible for the studyThe authors.FundingHas not received any funding.DisclosureAll authors have declared no conflicts of interest. (Source: Annals of Oncology)
Source: Annals of Oncology - October 1, 2019 Category: Cancer & Oncology Source Type: research

156PRecurrence risk evaluation in stage IB/IIA gastric cancer with TP53 codon 72 polymorphisms
ConclusionsAmong stage IB/IIA gastric cancer patients that underwent gastrectomy with curative-intent, post-operative adjuvant chemotherapy may be considered for patients carrying the TP53 codon 72 Pro/Pro polymorphism.Clinical trial identificationNCT01905969.Editorial acknowledgementChristopher Brooks of Bioscience Editing Solutions.Legal entity responsible for the studyThe authors.FundingMinistry of Education, Culture, Sports, Science and Technology, Japan.DisclosureY. Ohmori: Full / Part-time employment: Astellas Pharma Inc. (Source: Annals of Oncology)
Source: Annals of Oncology - October 1, 2019 Category: Cancer & Oncology Source Type: research

In-Hospital Mortality Risk Model of Gastric Cancer Surgery: Analysis of a Nationwide Institutional-Level Database With 94,277 Chinese Patients
The objective of this study is to identify independent risks and protective factors and to construct a mortality prediction model for gastrectomy in the Chinese population.Study design: This is a population-based prospective cohort at an institutional level. Seventy-two participating hospitals reported their annual gastrectomy data between 2014 and 2016, while 44 variables covering the institution and surgical information were included in the analysis. We used R software to encode and complete data pre-processing. The first difference model was applied to build the risk model. Data from 2014 and 2015 were assigned to risk ...
Source: Frontiers in Oncology - October 1, 2019 Category: Cancer & Oncology Source Type: research

Effects of Laparoscopic Sleeve Gastrectomy on Quality of Life Related to Gastroesophageal Reflux Disease
Journal of Laparoendoscopic&Advanced Surgical Techniques, Ahead of Print. (Source: Journal of Laparoendoscopic)
Source: Journal of Laparoendoscopic - October 1, 2019 Category: Surgery Authors: Andrea Balla Silvia Quaresima Livia Palmieri Ardit Seitaj Annamaria Pronio Danilo Badiali Abe Fingerhut Pietro Ursi Alessandro M. Paganini Source Type: research

Effects of Laparoscopic Sleeve Gastrectomy on Quality of Life Related to Gastroesophageal Reflux Disease
Journal of Laparoendoscopic&Advanced Surgical Techniques, Ahead of Print. (Source: Journal of Laparoendoscopic and Advanced Surgical Techniques)
Source: Journal of Laparoendoscopic and Advanced Surgical Techniques - October 1, 2019 Category: Surgery Authors: Andrea Balla Silvia Quaresima Livia Palmieri Ardit Seitaj Annamaria Pronio Danilo Badiali Abe Fingerhut Pietro Ursi Alessandro M. Paganini Source Type: research