Prognostic Value and Association of Sarcopenia and Systemic Inflammation for Patients with Gastric Cancer Following Radical Gastrectomy
AbstractObjective.The aim of this study was to investigate the prognostic value of preoperative sarcopenia and systemic inflammation for patients with resectable gastric cancer (GC) and develop a novel and powerful prognostic score based on these factors.Materials and Methods.Patients with GC who underwent radical gastrectomy between December 2009 and December 2013 were included. A multivariate Cox regression analysis was performed to identify the prognostic factors. A novel prognostic score (SLMR) was developed based on preoperative sarcopenia and the lymphocyte‐monocyte ratio (LMR), and its prognostic value was evaluat...
Source: The Oncologist - November 13, 2019 Category: Cancer & Oncology Authors: Jian-Xian Lin, Jun-Peng Lin, Jian-Wei Xie, Jia-bin Wang, Jun Lu, Qi-Yue Chen, Long-long Cao, Mi Lin, Ruhong Tu, Chao-Hui Zheng, Chang-Ming Huang, Ping Li Tags: Gastrointestinal Cancer Source Type: research

Systematic Review and Meta-Analysis of Randomised Controlled Trials Comparing Long-Term Outcomes of Roux-En-Y Gastric Bypass and Sleeve Gastrectomy
AbstractIntroductionSleeve gastrectomy (SG) has overtaken Roux-En-Y gastric bypass (RYGB) as the most common bariatric procedure worldwide. However, there is little long-term data comparing the two procedures.ObjectivesWe perform a systematic review and meta-analysis comparing 5-year outcomes of randomised controlled trials (RCTs) comparing RYGB and SG.MethodsMedline, Embase, The Cochrane Library, and NHS Evidence were searched for English language RCTs comparing RYGB with SG and assessed weight loss and/or comorbidity resolution at 5 years.ResultsFive studies were included in the final analysis. Meta-analysis demonstrates...
Source: Obesity Surgery - November 13, 2019 Category: Surgery Source Type: research

Comment on: Comparative Analysis of the Single Anastomosis Duodenal-Ileal Bypass with Sleeve Gastrectomy (SADI-S) to Established Bariatric Procedures: An Assessment of Two-Year Postoperative Data Illustrating Weight Loss, Diabetes Mellitus, and Nutritional Status in a Single US Center
SADIS was introduced in 2007 by S ánchez-Pernaute and is accepted as a modification of the widely accepted biliopancreatic diversion with duodeno switch (BPDDS). This paper from Enochs P, et al.1 represents an important addition to the body of growing literature regarding SADI-S and clinical outcomes. The comparison between SADI-S and established bariatric procedures is still limited and no papers either prospective or retrospective have examined weight loss, diabetes mellitus and nutritional status outcomes between SADI-S, RYGB and Sleeve Gastrectomy. (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - November 13, 2019 Category: Surgery Authors: Helmuth T. Billy Source Type: research

Alcohol ingestion symptoms after sleeve gastrectomy: intoxication or drunkenness? A prospective study from a Bariatric Centre of Excellence.
Abstract PURPOSE: The aim of this original research is to evaluate the effect of SG on alcohol intake symptoms, blood alcohol content (BAC), and alcohol metabolite levels. METHODS: At 0-6-12 months after SG, BAC of patients was measured at 0, 15, 30, and 60 min, and then every 30 min, and urinary metabolite (ethanol and acetaldehyde) levels were measured 2 h after consuming a standard red wine drink. Symptoms perceived by patients were evaluated using symptom alcoholization post-obesity surgery scores. RESULTS: Thirty obese patients (12 men/18 women; mean body mass index, 44 &p...
Source: Eating and weight disorders : EWD - November 13, 2019 Category: Eating Disorders & Weight Management Authors: Iossa A, Ciccioriccio MC, Zerbinati C, Guida A, Di Giacomo L, Silecchia G Tags: Eat Weight Disord Source Type: research

Comment on: Comparative analysis of the single-anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) to established bariatric procedures: an assessment of 2-year postoperative data illustrating weight loss, type 2 diabetes, and nutritional status in a single U.S. center
Single-anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S) was introduced in 2007 by S ánchez-Pernaute and is accepted as a modification of the widely accepted biliopancreatic diversion with duodenal switch. This paper from Enochs et al. [1] represents an important addition to the body of growing literature regarding SADI-S and clinical outcomes. The comparison between SADI-S and es tablished bariatric procedures is still limited and no papers, either prospective or retrospective, have examined weight loss, type 2 diabetes, and nutritional status outcomes between SADI-S, Roux-en-Y gastric bypass ...
Source: Surgery for Obesity and Related Diseases - November 13, 2019 Category: Surgery Authors: Helmuth T. Billy Tags: Editorial comment Source Type: research

Effect of Hospital Volume With Respect to Performing Gastric Cancer Resection on Recurrence and Survival: Results From the CRITICS Trial
Conclusions: In the CRITICS trial, hospitals with a high annual volume of gastric cancer surgery were associated with higher overall and DFS. These findings emphasize the value of centralizing gastric cancer surgeries in the Western world. (Source: Annals of Surgery)
Source: Annals of Surgery - November 12, 2019 Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research

Short-term Outcomes of a Multicenter Randomized Controlled Trial Comparing Laparoscopic Distal Gastrectomy With D2 Lymphadenectomy to Open Distal Gastrectomy for Locally Advanced Gastric Cancer (KLASS-02-RCT)
Conclusions: Laparoscopic distal gastrectomy with D2 lymphadenectomy for locally advanced gastric cancer shows benefits in terms of lower complication rate, faster recovery, and less pain compared with open surgery. (Source: Annals of Surgery)
Source: Annals of Surgery - November 12, 2019 Category: Surgery Tags: RANDOMIZED CONTROLLED TRIALS Source Type: research

Gastric Histopathologic Findings in South Italian Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy: Is Histopathologic Examination of All Resected Gastric Specimens Necessary?
ConclusionHistopathologic examination of LSG specimens may not be routinely needed and can be performed on selected patients. While we recommend routine preoperative UGIE in all LSG-treated patients, we suggest that histopathologic assessment of the LSG specimens should be mandatory when UGIE biopsies demonstrate HP infection and/or premalignant lesions, in all patients older than 42 years, and in cases of intraoperative detection of incidental tumours or suspicious lesions. (Source: Obesity Surgery)
Source: Obesity Surgery - November 12, 2019 Category: Surgery Source Type: research

Feasibility and Safety of Early Oral Feeding in Patients with Gastric Cancer After Radical Gastrectomy
This study aimed to evaluate the feasibility and safety of early oral feeding (EOF) for patients with gastric cancer after radical gastrectomy. The EOF protocol was implemented in 397 patients who underwent radical gastrectomy between 2005 and 2014 at our hospital. The protocol was common in 277 patients after distal gastrectomy (DG) and 120 patients after total gastrectomy (TG). The patients were scheduled to start drinking water in the morning of the first postoperative day and to start thin rice gruel with a liquid nutrition supplement on the second postoperative day. We analyzed the incidence of postoperative complicat...
Source: Indian Journal of Surgical Oncology - November 12, 2019 Category: Cancer & Oncology Source Type: research

Laparoscopic Roux-en-Y Double Fistulo-Jejunostomy for Chronic Gastric Leaks After Converted Vertical Banded Gastroplasty to Sleeve Gastrectomy
ConclusionsDouble LRYFJ for chronic leaks after complicated bariatric procedures seems safe with good postoperative outcomes. However, it remains a challenging procedure and should be reserved for selected patients in specialized bariatric centers. (Source: Obesity Surgery)
Source: Obesity Surgery - November 12, 2019 Category: Surgery Source Type: research

Short- and long-term outcomes of totally robotic versus robotic-assisted radical distal gastrectomy for advanced gastric cancer: a mono-institution retrospective study
By comparing short- and long-term outcomes following totally robotic radical distal gastrectomy (TRDG) and robotic-assisted radical distal gastrectomy (RADG), we aimed to assess in which modus operandi patient... (Source: World Journal of Surgical Oncology)
Source: World Journal of Surgical Oncology - November 11, 2019 Category: Cancer & Oncology Authors: Rui Luo, Dongning Liu, Shanping Ye, Hechun Tang, Weiquan Zhu, Penghui He, Cheng Tang and Taiyuan Li Tags: Research Source Type: research

Long-Term Changes in Leptin, Chemerin, and Ghrelin Levels Following Roux-en-Y Gastric Bypass and Laparoscopic Sleeve Gastrectomy
AbstractAimPublished reports showed conflicting results regarding the sustained alterations in leptin, chemerin, and ghrelin concenratios after metabolic surgery. Therefore, we performed the present work to contrast the alterations in leptin, chemerin, and ghrelin levels one year after Roux-en-Y gastric bypass (RYGB) versus laparoscopic sleeve gastrectomy (LSG).MethodsThe present research is a prospective, comparative one that followed 100 cases for whom RYGB or LSG was done. We assessed the serum values of adiposity-associated mediators, including adipokcytokines (leptin and active chemerin) and gastrointestinal hormones ...
Source: Obesity Surgery - November 11, 2019 Category: Surgery Source Type: research

Robotic Roux Limb Placement for Chronic Fistula After Sleeve Gastrectomy: a Novel Approach for a Technically Challenging Surgery?
(Source: Obesity Surgery)
Source: Obesity Surgery - November 11, 2019 Category: Surgery Source Type: research

Association of Serum Zinc Concentration with Preservation of Renal Function After Bariatric Surgery: a Retrospective Pilot Study
ConclusionThe results demonstrated a positive relationship between post-LSG serum zinc levels and preservation of renal function among patients with obesity in a surgical setting. Large-scale studies are warranted to support the findings. (Source: Obesity Surgery)
Source: Obesity Surgery - November 10, 2019 Category: Surgery Source Type: research

Surgical choice of proximal gastric cancer in china :a retrospective study of a 30-year experience from a single center in china.
Conclusion: Considering the survival benefits and preserved function, proximal gastrectomy can be performed safely in stage Ia and Ib gastric cancer (T1N0, T1N1, and T2N0) with an excellent remission rate. Proximal gastrectomy is not recommended for advanced gastric cancer. PMID: 31687853 [PubMed - as supplied by publisher] (Source: Expert Review of Gastroenterology and Hepatology)
Source: Expert Review of Gastroenterology and Hepatology - November 9, 2019 Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research

Splenic infarction: a dark side of the nephrotic syndrome
A 78-year-old man with type 2 diabetes, hypertension, chronic anemia and recent-onset nephrotic syndrome presented with a 1-day complain of abdominal pain on his left side. He did not report any other symptoms. In his medical history, he had a partial gastrectomy for cancer 3 years ago (Source: The American Journal of Medicine)
Source: The American Journal of Medicine - November 9, 2019 Category: General Medicine Authors: Giuseppe Famularo, Andrea Cortese Tags: Clinical Communication to the Editor Source Type: research

Do Mandated Weight Loss Goals Prior to Bariatric Surgery Improve Postoperative Outcomes?
ConclusionWLG group did not have decreased perioperative morbidity, nor improved weight loss and comorbidity resolution 4 years after surgery. While these findings should also be confirmed by multicenter trials, they question the value of mandated WLG prior to bariatric surgery as they seem ineffective and may limit patient access to surgery. (Source: Obesity Surgery)
Source: Obesity Surgery - November 9, 2019 Category: Surgery Source Type: research

Comparison of Weight Loss in Sleeve Gastrectomy Patients With and Without Antrectomy: a Prospective Randomized Study
ConclusionLSG with or without antrectomy is safe and effective for weight loss. Larger studies are required to identify patients likely to benefit from LSG with antrectomy. (Source: Obesity Surgery)
Source: Obesity Surgery - November 9, 2019 Category: Surgery Source Type: research

Management of leak after sleeve gastrectomy: outcomes of 73 cases, treatment algorithm and predictors of resolution.
ConclusionManagement of post-LSG leak is multimodal. Our clinical experience demonstrated less urge to perform extensive surgical interventions. Patients on enteral feeding had shorter resolution time while patients with sleeve stricture had a longer time to resolution. (Source: Obesity Surgery)
Source: Obesity Surgery - November 9, 2019 Category: Surgery Source Type: research

Risk Factors for Moderate to Severe Pain during the First 24  Hours after Laparoscopic Bariatric Surgery While Receiving Intravenous Patient-Controlled Analgesia.
Risk Factors for Moderate to Severe Pain during the First 24 Hours after Laparoscopic Bariatric Surgery While Receiving Intravenous Patient-Controlled Analgesia. Anesthesiol Res Pract. 2019;2019:6593736 Authors: Iamaroon A, Tangwiwat S, Nivatpumin P, Lertwacha T, Rungmongkolsab P, Pangthipampai P Abstract Objective: To investigate the incidence of and risk factors for moderate to severe pain during the first 24 hours after laparoscopic bariatric surgery. Materials and Methods: This retrospective study included morbidly obese patients who underwent laparoscopic sleeve gastrectomy or Ro...
Source: Anesthesiology Research and Practice - November 8, 2019 Category: Anesthesiology Tags: Anesthesiol Res Pract Source Type: research

Transversus abdominis plane block with general anesthesia blunts the perioperative stress response in patients undergoing radical gastrectomy
Surgical stress induces the release of neuroendocrine mediators and cytokines during perioperative period, which may have adverse effects on cancer patients. While the surgical stress responsse can be affected... (Source: BMC Anesthesiology)
Source: BMC Anesthesiology - November 7, 2019 Category: Anesthesiology Authors: Ruizhu Liu, Haiyan Qin, Meng Wang, Kai Li and Guoqing Zhao Tags: Research article Source Type: research

Conversion Surgery for Stage IV Gastric Cancer
This article reviews the current state of conversion surgery for unresectable stage IV GC. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - November 7, 2019 Category: Cancer & Oncology Source Type: research

Comparison of Early Oral Feeding With Traditional Oral Feeding After Total Gastrectomy for Gastric Cancer: A Propensity Score Matching Analysis
Background: The present study aimed to compare the feasibility and safety of early oral feeding (EOF) with traditional oral feeding (TOF) after radical total gastrectomy for gastric cancer.Methods: This retrospective study included consecutive patients who underwent total gastrectomy from April 2016 and November 2018. These patients were divided into two groups, according to their postoperative feeding protocol: EOF group (n = 314) and TOF group (n = 433). Propensity score matching was used to balance the potential confounders, and 276 patients were selected from each group. The EOF group received oral diet on postoperativ...
Source: Frontiers in Oncology - November 7, 2019 Category: Cancer & Oncology Source Type: research

Is it Worth it? Determining the Health Benefits of Sleeve Gastrectomy in Patients with a Body Mass Index Less than 35 kg/m2
Criteria for undergoing sleeve gastrectomy (SG) is restricted among patients with a body mass index (BMI) (Source: Surgery for Obesity and Related Diseases)
Source: Surgery for Obesity and Related Diseases - November 7, 2019 Category: Surgery Authors: Oliver A. Varban, Aaron J. Bonham, Jonathan F. Finks, Dana A. Telem, Nabeel R. Obeid, Amir A. Ghaferi Tags: Original articles Source Type: research

Effect of Biologic Material Reinforcement on Surgical Anastomosis After Gastrectomy —A Pilot Study
Conclusions: Leakage rate reduction with acellular dermal matrix reinforcement of anastomotic site was not detected in this investigation. However, postoperative inflammation levels and numerical predictors of anastomotic leakage development were significantly lower with acellular dermal matrix reinforcement of surgical anastomosis. This finding is worthy of further investigation, as reduction of inflammation with anastomotic site reinforcement is a novel finding, and more in-depth research may lead to discoveries on the physiologic role of the surgical anastomosis in post-gastrectomy patients. In addition, lower CRP and N...
Source: Frontiers in Oncology - November 6, 2019 Category: Cancer & Oncology Source Type: research

Esophagogastric junction adenocarcinomas: individualization of resection with special considerations for Siewert type II, and Nishi types EG, E=G and GE cancers
AbstractFor Siewert type II adenocarcinoma of the esophagogastric junction (AEG II), or similar tumors classified as Nishi EG, E=G, GE, the type of surgical resection and reconstruction should be individualized. Criteria for decision making mainly focus on the oral extent of esophageal infiltration, the cT and cN category and the functional status of the patient. For cT1/cT2 adenocarcinomas, which are non-poorly cohesive, intestinal type of Lauren Grading 1 or 2 without clinical signs of lymph node metastasis at the distal stomach, a limited transhiatal proximal gastrectomy with double tract reconstruction is recommended. ...
Source: Gastric Cancer - November 6, 2019 Category: Gastroenterology Source Type: research

Altered immune system in offspring of rat maternal vertical sleeve gastrectomy.
Abstract Obesity in women results in reduced fertility and increased complications during pregnancy. Vertical sleeve gastrectomy (VSG) effectively reduces weight, type-2 diabetes and dyslipidemia, but is also associated with preterm and small-for-gestational age births. The mechanism by which VSG impacts fetal development remains unknown. Here we hypothesize that previously reported immune changes during rat VSG pregnancy are reflected long-term in the immune system of the offspring. Offspring of VSG and Sham dams were evaluated at postnatal day (PND) 21 and PND60. At PND21, VSG pups have lower numbers of circulat...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - November 6, 2019 Category: Physiology Authors: Spann RA, Taylor EB, Welch BA, Grayson BE Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research

Omentopexy with Glubran ®2 for reducing complications after laparoscopic sleeve gastrectomy: results of a randomized controlled study
We report our pro... (Source: BMC Surgery)
Source: BMC Surgery - November 5, 2019 Category: Surgery Authors: Vincenzo Pilone, Salvatore Tramontano, Michele Renzulli, Mafalda Romano, Angela Monda, Alice Albanese and Mirto Foletto Tags: Research Source Type: research

Radical Gastrectomy: Still the Gold Standard Treatment for Gastric Cancer —Our Experience from a Tertiary Care Center from Northeast India
This study was conducted to assess the outcomes of all resectable gastric cancers that presented to our tertiary cancer center in Northeast India. All patients undergoing upfront surgery for gastric cancer with curative intention between 2012 and 2017 were included in the study. A total of 116 patients who underwent upfront radical gastrectomy were included in the study. Males (58.6%) were more common than females (41.4%). Mean age at presentation was 56.12 years (range 26 –89). The most common mode of presentation was pain abdomen (53.8%). The most common location of tumor was the distal part (81%) followed by the p...
Source: Indian Journal of Surgical Oncology - November 5, 2019 Category: Cancer & Oncology Source Type: research

Reply to Letter to Editor RE: Laparoscopic Sleeve Gastrectomy After Endoscopic Sleeve Gastroplasty: Technical Aspects and Short-Term Outcomes
(Source: Obesity Surgery)
Source: Obesity Surgery - November 5, 2019 Category: Surgery Source Type: research

EWGSOP2 Versus EWGSOP1 for sarcopenia to predict prognosis in patients with gastric cancer after radical gastrectomy: analysis from a large-scale prospective study
This study aimed to investigate the association of sarcopenia and survival and compare the prognostic effects of sarcopenia as defined by EWGSOP1 and EWGSOP2 after gastrectomy. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 5, 2019 Category: Nutrition Authors: Cheng-Le Zhuang, Xian Shen, Hong-Bo Zou, Qian-Tong Dong, Hui-Yang Cai, Xiao-Lei Chen, Zhen Yu, Su-Lin Wang Tags: Original article Source Type: research

Impact of postoperative complications on long-term outcomes of patients following surgery for gastric cancer: A systematic review and meta-analysis of 64 follow-up studies.
Abstract Gastrectomy for cancer is a technically demanding procedure, with postoperative complications (POCs) reported to be in the range of 20%-46%. However, the effect of POCs on long-term survival of gastric cancer patients following surgery is far from conclusive. This systemic review aimed to determine the impact of postoperative complications (POCs) on the long-term survival of patients following surgery for gastric cancer. A systematic electronic search of PubMed and Scopus was performed from inception to June 26, 2018 to identify studies that described the relationship between POCs and long-term survival. ...
Source: Asian Journal of Surgery - November 5, 2019 Category: Surgery Authors: Li J, Zhang Y, Hu DM, Gong TP, Xu R, Gao J Tags: Asian J Surg Source Type: research

Colistin resistance in Acinetobacter baumannii isolated from critically ill patients: clinical characteristics, antimicrobial susceptibility and outcome
Conclusion: There is an increase of colistin resistance among clinical isolates ofAcinetobacter baumannii causing serious infections especially in critically ill patients.Keywords:Acinetobacter baumannii, colistin resistance, clinical characteristics. (Source: African Health Sciences)
Source: African Health Sciences - November 4, 2019 Category: African Health Source Type: research

Gastrectomy case volume and textbook outcome: an analysis of the Population Registry of Esophageal and Stomach Tumours of Ontario (PRESTO)
ConclusionsHigher case volume can impact certain measures of quality of care but may not address all care structures necessary for ideal Textbook recovery. Future quality improvement strategies should consider using case-mix adjusted Textbook Outcome rates as a surgical quality metric. (Source: Gastric Cancer)
Source: Gastric Cancer - November 4, 2019 Category: Gastroenterology Source Type: research

Opioid-like peptides and ghrelin mitigation of sleeve gastrectomy results depends on obesity level.
CONCLUSIONS: The activity of endogenous peptides in bariatric patients is connected with the obesity degree. Ghrelin level increases are negatively correlated with native Met-enkephalin changes shortly after bariatric surgery. The interplay of ghrelin and opioids might be consider as a predictor of postoperative weight loss success. PMID: 31681979 [PubMed - as supplied by publisher] (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - November 4, 2019 Category: Endocrinology Authors: Dyaczyński M, Scanes CG, Drożdż M, Wylężek L, Rzepa A, Cieśla A, Pierzchała-Koziec K Tags: Endokrynol Pol Source Type: research

A Rare Case of Incidental Finding of GIST during Sleeve Gastrectomy: Case Report
ConclusionAs a conclusion, we recommend keeping in mind incidental finding of GIST during abdominal surgeries and especially Sleeve gastrectomy, in order to detect this tumor as earlier as possible and have a good prognosis with a low chance for recurrence. (Source: International Journal of Surgery Case Reports)
Source: International Journal of Surgery Case Reports - November 3, 2019 Category: Surgery Source Type: research

Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial
Publication date: Available online 31 October 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Dag Hofsø, Farhat Fatima, Heidi Borgeraas, Kåre Inge Birkeland, Hanne Løvdal Gulseth, Jens Kristoffer Hertel, Line Kristin Johnson, Morten Lindberg, Njord Nordstrand, Milada Cvancarova Småstuen, Darko Stefanovski, Marius Svanevik, Tone Gretland Valderhaug, Rune Sandbu, Jøran HjelmesæthSummaryBackgroundFor patients with obesity and type 2 diabetes, weight loss improves insulin sensitivity and β-cell function, and can induce remission of diabetes. The comparative efficacy of ...
Source: The Lancet Diabetes and Endocrinology - November 2, 2019 Category: Endocrinology Source Type: research

Cancers, Vol. 11, Pages 1715: Conversion Surgery with HIPEC for Peritoneal Oligometastatic Gastric Cancer
Conclusion: Conversion surgery, including extended gastrectomy and multi-organ resections followed by HIPEC performed after systemic chemotherapy therapy for GC with PM is justified in downstaged patients with ypT2 and limited (less than P3) PM. (Source: Cancers)
Source: Cancers - November 2, 2019 Category: Cancer & Oncology Authors: Mielko Rawicz-Pruszy ński Sk órzewska Cise ł Piku ła Kwietniewska G ęca S ędłak Kurylcio Polkowski Tags: Article Source Type: research

Change in serum polyamine metabolome pattern after bariatric surgery in obese patients with metabolic syndrome.
CONCLUSION: Our study indicates that bariatric surgery affects the serum polyamine pattern and the resolution of metabolic syndrome after bariatric surgery is associated to specific changes in the serum polyamine metabolome. PMID: 31813775 [PubMed - as supplied by publisher] (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - November 2, 2019 Category: Surgery Authors: Ocaña-Wilhelmi L, Cardona F, Garrido-Sanchez L, Fernandez-Garcia D, Tinahones FJ, Ramos-Molina B Tags: Surg Obes Relat Dis Source Type: research

Effect of Yiqi Huayu Jiedu decoction on stages II and III gastric cancer: A multicenter, prospective, cohort study
Conclusion: YHJD decoction is effective in improving DFS rate in patients with gastric cancer stage III after radical gastrectomy. Moreover, it can reduce the risk of recurrence and metastasis and improve the quality of life in patients with gastric cancer stage II or III after radical gastrectomy. (Source: Medicine)
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

Safety and efficacy of laparoscopic gastrectomy in obese patients with gastric cancer
The present study aimed to investigate the safety and short-term outcome of laparoscopy-assisted distal radical gastrectomy in treating gastric cancer among obese patients. Perioperative outcomes were compared between 67 gastric cancer patients with a body mass index (BMI) ≥25 kg/m2 (obese group) and 198 ones with BMI  .05). There were significant differences between the 2 groups in operation time (non-obese: [234.2 ± 67.1] minutes vs obese group: [259.4 ± 78.5]; P = .017), postoperative hospital stay (obese group [19.7 ± 14.8] day vs non-obese [15.4 ± 7.1], P =...
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

A CARE-compliant case report: total pancreatectomy and total gastrectomy to treat pancreatic ductal adenocarcinoma
Rationale: Total pancreatectomy (TP) is performed in cases of multifocal and large invasive tumors of the pancreas, and is associated with high rates of mortality and morbidity. Previously, the limitations and unsatisfactory effect of this surgery rendered it rarely performed; however, with improvements in surgical techniques and blood sugar management, TP is now more frequently performed. TP has a similar long-term survival rate as that for pancreatoduodenectomy (PD). However, the application of TP plus total gastrectomy (TG) for the treatment of invasive pancreatic ductal adenocarcinoma has not been reported previously...
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Is Roux-en-Y or Billroth-II reconstruction the preferred choice for gastric cancer patients undergoing distal gastrectomy when Billroth I reconstruction is not applicable? A meta-analysis
Background: Although Billroth II and Roux-en-Y procedures are the two most commonly performed types of reconstruction techniques following distal stomach resection, there is yet no consensus on which reconstruction is the best choice. This meta-analysis aims to compare the perioperative safety and long-term complications of Billroth-II and Roux-en-Y reconstruction. Method: We searched the databases of the PubMed, the Cochrane Library, Web of Science, EMBASE, and the Chinese Biomedicine Database from January 2000 to January 2018 and included studies that compared Roux-en-Y with Billroth-II reconstruction after distal g...
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Multi-Modality Treatment for Patients With Metastatic Gastric Cancer: A Real-World Study in China
Introduction: People with metastatic gastric cancer (GC) have a poor prognosis. The study aims to investigate the efficacy of multi-modality treatment for patients with metastatic GC.Methods: We retrospectively identified 267 patients with stage IV gastric cancer who were treated with systemic chemotherapy: 114 received multi-modality treatments, 153 received systematic chemotherapy alone. The survival of these two groups was compared by log rank test, the independent prognostic factors were investigated using univariate and multivariate analyses.Results: The median survival of metastatic GC patients who received multi-mod...
Source: Frontiers in Oncology - November 1, 2019 Category: Cancer & Oncology Source Type: research

Perioperative Practices Concerning Sleeve Gastrectomy – a Survey of 863 Surgeons with a Cumulative Experience of 520,230 Procedures
ConclusionThere is a considerable variation in the perioperative practices concerning SG. Data can help in identifying areas for future consensus building and more focussed studies. (Source: Obesity Surgery)
Source: Obesity Surgery - November 1, 2019 Category: Surgery Source Type: research

Definitions of Long-Term Weight Regain and Their Associations with Clinical Outcomes
AbstractIntroductionThe prevalence and clinical significance of weight regain after bariatric surgery remains largely unclear due to the lack of a standardized definition of significant weight regain. The development of a clinically relevant definition of weight regain requires a better understanding of its clinical significance.ObjectivesTo assess rates of weight regain 5  years after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG), applying six definitions and investigating their association with clinical outcomes.MethodsPatients were followed up until 5  years after surgery and weight regain was ca...
Source: Obesity Surgery - November 1, 2019 Category: Surgery Source Type: research

Total Gastrectomy for CDH-1 Mutation Carriers: An Institutional Experience
Gastric cancer is a leading cause of cancer-related death across the world. A subset of gastric cancers demonstrates an inherited genetic predisposition. Individuals with germline mutations in the CDH1 gene incur a lifetime risk for diffuse gastric cancer and benefit from prophylactic gastrectomy. The results for this operative intervention remain relatively undescribed in the literature, despite guidelines supporting its use. (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - November 1, 2019 Category: Surgery Authors: Sandra R. DiBrito, Alex B. Blair, Vishnu Prasath, Mehran Habibi, John W. Harmon, Mark D. Duncan Source Type: research

Endoscopic septotomy and dilation of chronic sleeve gastrectomy leak.
PMID: 31783971 [PubMed - in process] (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - November 1, 2019 Category: Surgery Authors: Fazi J, Nasr J, Szoka N Tags: Surg Obes Relat Dis Source Type: research

Predicting the quality of surgical exposure using spatial and procedural features from laparoscopic videos
Conclusion  This preliminary study validates that a prediction of the surgical exposure from spatial features is possible. The analysis of the clusters of feature selected by the algorithm also shows encouraging results and potential clinical interpretations. (Source: International Journal of Computer Assisted Radiology and Surgery)
Source: International Journal of Computer Assisted Radiology and Surgery - October 31, 2019 Category: Intensive Care Source Type: research

Muscle mass, assessed at diagnosis by L3-CT scan as a prognostic marker of clinical outcomes in patients with gastric cancer: a systematic review and meta-analysis
Computed tomographic (CT) imaging at third lumbar vertebra (L3), routinely used by oncologists, represents a reliable tool to quantify muscle mass. A systematic review and meta-analysis was performed to assess the efficacy of CT scan to define muscle mass as a prognostic marker in GC patients undergoing gastrectomy and/or chemotherapy. The primary outcomes were overall survival (OS) and recurrence-free survival (RFS) and the secondary outcomes included postoperative length of hospital stay (P-LOS), total and severe complications in GC patients undergoing gastrectomy. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 31, 2019 Category: Nutrition Authors: Emanuele Rinninella, Marco Cintoni, Pauline Raoul, Carmelo Pozzo, Antonia Strippoli, Emilio Bria, Giampaolo Tortora, Antonio Gasbarrini, Maria Cristina Mele Tags: Meta-analyses Source Type: research