Severe Myocardial Necrosis and Acute Allograft Failure from Fulminant Clostridium Perfringens Sepsis
Immunosuppression after transplantation increases the risk of infections. Clostridium (C) bacteremia and spontaneous gas gangrene of solid organs is rare, almost exclusively seen in immunocompromised patients, and associated with high mortality. Here we present a case of rapidly progressive and ultimately fatal C. perfringens septicemia following heart transplantation (HT). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: H. Rosenblum, C. Lee, E.M. DeFilippis, F. Latif, J. Fried, D. Lotan, K. Clerkin, J. Aaron, K. Takeda, Y. Kaku, D. Santoriello, G. Sayer, N. Uriel, J. Raikhelkar Tags: (459) Source Type: research

Spectrum of imaging findings in soft-tissue necrosis
AbstractSoft tissue necrosis can occur at different tissue levels, with numerous underlying causes. In this pictorial review, we highlight myonecrosis, and its accompanying stages, fat necrosis, devitalized soft tissue seen with infection, and necrotizing soft tissue infections. Imaging examples are provided with each entity. (Source: Emergency Radiology)
Source: Emergency Radiology - April 1, 2023 Category: Emergency Medicine Source Type: research

Gas gangrene caused by spontaneous Clostridium septicum infection: A case study
Anaerobe. 2023 Mar 13:102719. doi: 10.1016/j.anaerobe.2023.102719. Online ahead of print.NO ABSTRACTPMID:36921887 | DOI:10.1016/j.anaerobe.2023.102719 (Source: Anaerobe)
Source: Anaerobe - March 15, 2023 Category: Microbiology Authors: Pia Heino Veikko Schepel Hanna Malmi Tiina Jahkola Source Type: research

Gas gangrene caused by spontaneous Clostridium septicum infection: A case study
Anaerobe. 2023 Mar 13:102719. doi: 10.1016/j.anaerobe.2023.102719. Online ahead of print.NO ABSTRACTPMID:36921887 | DOI:10.1016/j.anaerobe.2023.102719 (Source: Anaerobe)
Source: Anaerobe - March 15, 2023 Category: Microbiology Authors: Pia Heino Veikko Schepel Hanna Malmi Tiina Jahkola Source Type: research

Gas gangrene caused by spontaneous Clostridium septicum infection: A case study
Anaerobe. 2023 Mar 13:102719. doi: 10.1016/j.anaerobe.2023.102719. Online ahead of print.NO ABSTRACTPMID:36921887 | DOI:10.1016/j.anaerobe.2023.102719 (Source: Anaerobe)
Source: Anaerobe - March 15, 2023 Category: Microbiology Authors: Pia Heino Veikko Schepel Hanna Malmi Tiina Jahkola Source Type: research

Gas gangrene caused by spontaneous Clostridium septicum infection: A case study
Anaerobe. 2023 Mar 13:102719. doi: 10.1016/j.anaerobe.2023.102719. Online ahead of print.NO ABSTRACTPMID:36921887 | DOI:10.1016/j.anaerobe.2023.102719 (Source: Anaerobe)
Source: Anaerobe - March 15, 2023 Category: Microbiology Authors: Pia Heino Veikko Schepel Hanna Malmi Tiina Jahkola Source Type: research

Diabetic myonecrosis of isolated internal oblique muscle, a rare presentation of an uncommon condition: A case report
AbstractIntroductionDiabetic myonecrosis is usually encountered in patients with long-standing diabetes mellitus, particularly those with uncontrolled glycemia and target organ damage. It is considered a form of microangiopathy and commonly involves large muscles of the lower extremities. Upper limb muscles are involved infrequently, and involvement of trunk muscles is extremely rare. Isolated involvement of abdominal muscle has never been reported so far.Case reportA 50-year-old gentleman with fifteen-year history of type 2 diabetes mellitus presented with pain and swelling of left lumbar region for the preceding two week...
Source: International Journal of Diabetes in Developing Countries - March 9, 2023 Category: Endocrinology Source Type: research

Atraumatic Acute Paraspinal Compartment Syndrome in a Patient With McArdle's Disease
Am Surg. 2023 Mar 3:31348231161694. doi: 10.1177/00031348231161694. Online ahead of print.ABSTRACTA 60-year-old male presented to the emergency room with complaints of back pain overlying the left lumbar area and ipsilateral thigh numbness. The left erector spinae musculature was rigid, tense, and painful to palpation. An elevated serum creatine kinase was identified, and a computed tomography scan showed evidence of left paraspinal musculature congestion. Past medical/surgical history was significant for McArdle's disease and bilateral forearm fasciotomies. The patient underwent lumbosacral fasciotomy with no obvious myon...
Source: The American Surgeon - March 3, 2023 Category: Surgery Authors: Aaron B Pollock John C Huggins Kevin N Harrell Source Type: research

Atraumatic Acute Paraspinal Compartment Syndrome in a Patient With McArdle's Disease
Am Surg. 2023 Mar 3:31348231161694. doi: 10.1177/00031348231161694. Online ahead of print.ABSTRACTA 60-year-old male presented to the emergency room with complaints of back pain overlying the left lumbar area and ipsilateral thigh numbness. The left erector spinae musculature was rigid, tense, and painful to palpation. An elevated serum creatine kinase was identified, and a computed tomography scan showed evidence of left paraspinal musculature congestion. Past medical/surgical history was significant for McArdle's disease and bilateral forearm fasciotomies. The patient underwent lumbosacral fasciotomy with no obvious myon...
Source: The American Surgeon - March 3, 2023 Category: Surgery Authors: Aaron B Pollock John C Huggins Kevin N Harrell Source Type: research

IDF2022-0305 A Study of Diabetic Muscle Infarction and Its Association with Long-Standing and Poorly Controlled Diabetes Mellitus
Diabetic myonecrosis or diabetic muscle infarction, is a very rare and under-recognised complication of poorly controlled long-standing diabetes mellitus, which entailing the spontaneous ischemic necrosis of skeletal muscle. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - March 1, 2023 Category: Endocrinology Authors: M. Bera, R. Ahmed Tags: Education and Integrated Care Source Type: research

Beyond the abdominal and pelvic cavity: abdominal wall and spinal “Aunt Minnies”
AbstractAbdominal wall and spinal soft tissue findings are frequently encountered on CT or MR imaging of the abdomen and pelvis. Many of these entities have specific imaging findings, for which a definitive diagnosis can be made without the need for further work up. These abdominal wall and spinal findings may be diagnostically challenging for sub-specialized abdominal radiologists who are unfamiliar with their appearance and appropriate management. This review article describes and illustrates pathognomonic or characteristic abdominal wall and spinal pathologies, which reside outside the abdominopelvic cavity. The cases s...
Source: Abdominal Imaging - February 15, 2023 Category: Radiology Source Type: research

Molecules, Vol. 28, Pages 929: The Cardioprotective Effect of Corosolic Acid in the Diabetic Rats: A Possible Mechanism of the PPAR- & gamma; Pathway
In conclusion, our results prove that corosolic acid can ameliorate ISO-induced acute myocardial injury in rats. Based on these results, corosolic acid seems to be a viable new target for the treatment of cardiovascular diseases and other diseases of a similar nature. (Source: Molecules)
Source: Molecules - January 17, 2023 Category: Chemistry Authors: Faisal K. Alkholifi Sushma Devi Hasan S. Yusufoglu Aftab Alam Tags: Article Source Type: research

Case report: Diabetic muscle infarction with diabetic ketoacidosis: A rare complication of diabetes
ConclusionDMI is a rare DM complication with a high recurrence rate, commonly presenting with chronic complications, while our case report shows that acute diabetes decompensation, such as DKA, can stimulate the occurrence and development of DMI. Timely diagnosis and appropriate treatment could shorten the recovery time. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - January 12, 2023 Category: Endocrinology Source Type: research

Radiomics-based machine learning models in STEMI: a promising tool for the prediction of major adverse cardiac events
ConclusionThe radiomics-based ML models incorporating clinical and conventional MRI parameters are promising for predicting MACE occurrence in STEMI patients in the follow-up period.Key Points•Acute coronary occlusion results in variable changes at the cellular level ranging from myocyte swelling to myonecrosis depending on the duration of the ischemia and the metabolic state of the heart, which causes subtle heterogeneous signal changes that are imperceptible to the human eye with cardiac MRI.•Radiomics-based machine learning analysis of cardiac MR images is promising for risk prediction.•Combining MRI-derived param...
Source: European Radiology - January 12, 2023 Category: Radiology Source Type: research

Spectrum of imaging findings in soft-tissue necrosis
AbstractSoft tissue necrosis can occur at different tissue levels, with numerous underlying causes. In this pictorial review, we highlight myonecrosis, and its accompanying stages, fat necrosis, devitalized soft tissue seen with infection, and necrotizing soft tissue infections. Imaging examples are provided with each entity. (Source: Emergency Radiology)
Source: Emergency Radiology - January 10, 2023 Category: Emergency Medicine Source Type: research