Gas Gangrene (Myonecrosis) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Partial efficacy of a Brazilian coralsnake antivenom and varespladib in neutralizing distinct toxic effects induced by sublethal Micrurus dumerilii carinicauda envenoming in rats
Toxicon. 2022 Apr 27:S0041-0101(22)00116-7. doi: 10.1016/j.toxicon.2022.04.014. Online ahead of print.ABSTRACTIn this work, we report the efficacy of a combination of Brazilian therapeutic coralsnake antivenom (CAV) and varespladib (phospholipase A2 inhibitor - VPL) in partially neutralizing selected toxic effects of Micrurus dumerilii carinicauda coralsnake venom in rats. Venom caused local myonecrosis and systemic neurotoxicity, nephrotoxicity, and hepatotoxicity within 2 h of injection. CAV and VPL administered separately failed to prevent most of these alterations. However, a combination of CAV plus VPL offered variabl...
Source: Toxicon - April 30, 2022 Category: Toxicology Authors: Rosimeire Silva-Carvalho Matheus Z Gaspar Luiz H B Quadros Lu ís G G Lobo Rog ério Giuffrida Cec ília L Santarém Elisangela O Silva Juliana R Gerez Nelson J Silva Stephen Hyslop Bruno Lomonte Rafael S Floriano Source Type: research

Fatal necrotizing fasciitis with clostridium perfringens infection following resection of soft tissue sarcoma of the thigh
We present the case of a 57-year-old male patient with a fatal outcome after resection of a soft tissue sarcoma of the lateral thigh. A polymicrobial surgical site infection with Staphylococcus lugdunensis and Clostridium perfringens caused fulminant necrotising fasciitis with an additional gas gangrene. The patient suffered a severe sepsis with consecutive haemolysis and multiorgan failure. The authors recapitulate the deadly progress of a rarely reported complication after oncological resection. The therapeutic approach and surgical interventions are discussed based on the current literature.PMID:35419785 | DOI:10.1055/a...
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - April 14, 2022 Category: Cosmetic Surgery Authors: Alexander Sogorski Maria Bernstorff Marcus Lehnhardt Bj örn Behr Johannes Maximilian Wagner Source Type: research