Sequence based HLA-DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in The Gambia
Hum Immunol. 2022 Nov 2:S0198-8859(22)00226-9. doi: 10.1016/j.humimm.2022.10.009. Online ahead of print.ABSTRACTClass II HLA loci DRB1, DQB1 and DPB1 were typed for a total of 939 Gambian participants by locus-specific amplicon sequencing. Participants were from multiple regions of The Gambia and drawn from two studies: a family study aiming to identify associations between host genotype and trachomatous scarring (N = 796) and a cohort study aiming to identify correlates of immunity to trachoma (N = 143). All loci deviated from Hardy-Weinberg equilibrium, likely due to the family-based nature of the study: 608 participants...
Source: Human Immunology - November 5, 2022 Category: Allergy & Immunology Authors: Amber Barton Harry Pickering Thomas Payne Nkoyo Faal Ansumana Sillah Anna Harte Robin L Bailey David C W Mabey Chrissy H Roberts Martin J Holland Source Type: research
Sequence based HLA-DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in The Gambia
Hum Immunol. 2022 Nov 2:S0198-8859(22)00226-9. doi: 10.1016/j.humimm.2022.10.009. Online ahead of print.ABSTRACTClass II HLA loci DRB1, DQB1 and DPB1 were typed for a total of 939 Gambian participants by locus-specific amplicon sequencing. Participants were from multiple regions of The Gambia and drawn from two studies: a family study aiming to identify associations between host genotype and trachomatous scarring (N = 796) and a cohort study aiming to identify correlates of immunity to trachoma (N = 143). All loci deviated from Hardy-Weinberg equilibrium, likely due to the family-based nature of the study: 608 participants...
Source: Human Immunology - November 5, 2022 Category: Allergy & Immunology Authors: Amber Barton Harry Pickering Thomas Payne Nkoyo Faal Ansumana Sillah Anna Harte Robin L Bailey David C W Mabey Chrissy H Roberts Martin J Holland Source Type: research
Ethylene glycol disputed as cause of children’s deaths in the Gambia
(Source: Chemical and Engineering News)
Source: Chemical and Engineering News - November 3, 2022 Category: Chemistry Authors: K. V. Venkatasubramanian, special to C&EN Source Type: research
Longitudinal change in bone density, geometry and estimated bone strength in older men and women from The Gambia: Findings from The Gambian Bone and Muscle Aging Study (GamBAS)
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 22, 2022 Category: Orthopaedics Authors: M ícheál Ó Breasail,
Camille Parsons,
Ayse Zengin,
Landing Jarjou,
Cyrus Cooper,
Peter R Ebeling,
Ann Prentice,
Kate A Ward Tags: Research Article Source Type: research
Clinical handover communication at maternity shift changes and women's safety in Banjul, the Gambia: a mixed-methods study
Clinical handover is a vital communication process for patient safety; transferring patient responsibility between healthcare professionals (HCPs). Exploring handover processes in maternity care is fundamental... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - October 21, 2022 Category: OBGYN Authors: Faith Rickard, Fides Lu, Lotta Gustafsson, Christine MacArthur, Carole Cummins, Ivan Coker, Amie Wilson, Kebba Mane, Kebba Manneh and Semira Manaseki-Holland Tags: Research Source Type: research
Exploring the nexus between natural resource depletion, renewable energy use, and environmental degradation in sub-Saharan Africa
This study explores the nexus between natural resource depletion, renewable energy use, and environmental degradation in 48 sub-Saharan African (SSA) countries from the period 2000 to 2020 using generalized panel quantile regression. The findings show that, at 90th quantiles the magnitude of natural resource depletion is positive and stronger associated with environmental degradation in SSA. This is probably attributed by countries with higher natural resource depletion such as Congo Republic (37.10%), Equatorial Guinea (27.60%), Angola (21.14%), Gabon (12.84%), Chad (12.19%), Burundi (8.92%), Uganda (6.16%), and Congo Dem...
Source: Environmental Science and Pollution Research International - October 14, 2022 Category: Environmental Health Authors: Mwoya Byaro Juvenal Nkonoki Gemma Mafwolo Source Type: research
Exploring the nexus between natural resource depletion, renewable energy use, and environmental degradation in sub-Saharan Africa
This study explores the nexus between natural resource depletion, renewable energy use, and environmental degradation in 48 sub-Saharan African (SSA) countries from the period 2000 to 2020 using generalized panel quantile regression. The findings show that, at 90th quantiles the magnitude of natural resource depletion is positive and stronger associated with environmental degradation in SSA. This is probably attributed by countries with higher natural resource depletion such as Congo Republic (37.10%), Equatorial Guinea (27.60%), Angola (21.14%), Gabon (12.84%), Chad (12.19%), Burundi (8.92%), Uganda (6.16%), and Congo Dem...
Source: Environmental Science and Pollution Research International - October 14, 2022 Category: Environmental Health Authors: Mwoya Byaro Juvenal Nkonoki Gemma Mafwolo Source Type: research
IJERPH, Vol. 19, Pages 13045: The Influence of Parental Environmental Exposure and Nutrient Restriction on the Early Life of Offspring Growth in Gambia & mdash;A Pilot Study
Conclusion: This study was able to ascertain if the maternal diet during gestation, toxicant exposure, maternal stress, and parental smoking habits have an influence on the early life of offspring. While the study recommends a large sample size study to eliminate selection bias, there should be an increased level of awareness of mothers of their offspring’s health and their husbands’ lifestyles that might influence the adulthood health of their offspring. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - October 11, 2022 Category: Environmental Health Authors: Ousman Bajinka Amadou Barrow Sang Mendy Binta J. J. Jallow Jarry Jallow Sulayman Barrow Ousman Bah Saikou Camara Modou Lamin Colley Sankung Nyabally Amie N. Joof Mingming Qi Yurong Tan Tags: Article Source Type: research
Doing ‘reciprocity work’: The role of fieldworkers in a mass drug administration trial in the Gambia
. (Source: Global Public Health)
Source: Global Public Health - October 2, 2022 Category: International Medicine & Public Health Authors: Alexandra Fehr Claudia Nieto-Sanchez Joan Muela Ebrima Manneh Dullo Baldeh Omar Ceesay Umberto D ’Alessandro Edgard Dabira Patricia Kingori Koen Peeters Grietens Azucena Bardaj í Joske Bunders-Aelen Teun Zuiderent-Jerak Source Type: research
Attendance and vaccination at immunization clinics in rural Gambia before and during the COVID-19 pandemic
CONCLUSION: The reduced EPI attendance during the pandemic interruption period lasted only 3 months. Significant recovery in EPI attendance occurred during the late recovery period, while rates of monthly immunization returned to pre-pandemic levels for most antigens. EPI programmes should implement strategies to deliver missed antigens when infants do present to EPI clinics, aware that missed doses may be age dependent.PMID:36180374 | PMC:PMC9468317 | DOI:10.1016/j.vaccine.2022.09.031 (Source: Vaccine)
Source: Vaccine - September 30, 2022 Category: Allergy & Immunology Authors: Isaac Osei Golam Sarwar Ilias Hossain Kemo Sonko Lamin Ceesay Bubacarr Baldeh Ebba Secka Grant A Mackenzie Source Type: research
Clinical manifestations and outcomes of severe malaria in adult patients admitted to a tertiary hospital in the Gambia
Malaria is a major public health concern in The Gambia. There is limited data on the clinical manifestation and outcome of severe malaria in adult patients in The Gambia. The study therefore assessed the clini... (Source: Malaria Journal)
Source: Malaria Journal - September 21, 2022 Category: Infectious Diseases Authors: Sheikh Omar Bittaye, Abubacarr Jagne, Lamin ES Jaiteh, Behzad Nadjm, Alfred Amambua-Ngwa, Abdul Karim Sesay, Yankuba Singhateh, Emmanuel Effa, Ousman Nyan and Ramou Njie Tags: Research Source Type: research
Study protocol for a phase 1/2, single-centre, double-blind, double-dummy, randomized, active-controlled, age de-escalation trial to assess the safety, tolerability and immunogenicity of a measles and rubella vaccine delivered by a microneedle patch in healthy adults (18 to 40 years), measles and rubella vaccine-primed toddlers (15 to 18 months) and measles and rubella vaccine-na ïve infants (9 to 10 months) in The Gambia [Measles and Rubella Vaccine Microneedle Patch Phase 1/2 Age De-escalation Trial]
New strategies to increase measles and rubella vaccine coverage, particularly in low- and middle-income countries, are needed if elimination goals are to be achieved. With this regard, measles and rubella vacc... (Source: Trials)
Source: Trials - September 14, 2022 Category: General Medicine Authors: Ikechukwu Adigweme, Edem Akpalu, Mohammed Yisa, Simon Donkor, Lamin B. Jarju, Baba Danso, Anthony Mendy, David Jeffries, Abdoulie Njie, Andrew Bruce, Michael Royals, James L. Goodson, Mark R. Prausnitz, Devin McAllister, Paul A. Rota, Sebastien Henry & he Tags: Study protocol Source Type: research
Prevalence and factors associated with the awareness of obstetric fistula among women of reproductive age in The Gambia: a multilevel fixed effects analysis
An obstetric fistula is an inappropriate connection between the vagina, rectum, or bladder that results in faecal or urine incontinence. Young women from rural areas with poor socioeconomic situations and educ... (Source: BMC Public Health)
Source: BMC Public Health - September 13, 2022 Category: Consumer Health News Authors: Agani Afaya, Alhassan Sibdow Abukari and Shamsudeen Mohammed Tags: Research Source Type: research
Availability of services for the diagnosis and treatment of infertility in The Gambia`s public and private health facilities: a cross-sectional survey
Infertility is a long-standing reproductive health issue, which affects both men and women worldwide and it is especially problematic in the Global South. In sub-Saharan Africa, understanding the current avail... (Source: BMC Health Services Research)
Source: BMC Health Services Research - September 7, 2022 Category: General Medicine Authors: Anna Afferri, Haddijatou Allen, Susan Dierickx, Mustapha Bittaye, Musa Marena, Allan Pacey and Julie Balen Tags: Research Source Type: research
