Obstetric outcome of female genital mutilation in the Gambia – an observational study
This study aimed to provide national data on obstetric outcomes to support advocacy and health education.A multicentre observational study to assess the obstetric and neonatal outcomes of parturient women with and without FGM/Cwas carried out across 4 healthcare facilities in The Gambia. The primary outcome was postpartum haemorrhage (>500ml) andsecondary outcomes were caesarean section, perineal tears (including episiotomy), neonatal resuscitation and perinatal death.Of the 1,569 participants recruited into the study, 23% had no FGM/C while 77% had FGM/C of varying severity. The riskof postpartum haemorrhage was double...
Source: African Health Sciences - December 23, 2022 Category: African Health Authors: Patrick Idoko, Alice Armitage, Momodou T Nyassi, Lucas Jatta, Neneh Bah, Awa Jah, Dado Jabbie, Mustapha Bittaye Source Type: research
Quantifying Excess Mortality during the Covid-19 pandemic in 2020 in The Gambia: A time-series analysis of three Health and Demographic Surveillance Systems
INTRODUCTION (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - December 22, 2022 Category: Infectious Diseases Authors: Nuredin I. Mohammed, Grant Mackenzie, Esu Ezeani, Mamadi Sidibeh, Lamin Jammeh, Golam Sarwar, Aji Kumba Folawiyo Saine, Bakary Sonko, Pierre Gomez, Bai Lamin Dondeh, M. Jahangir Hossain, Momodou Jasseh, Effua Usuf, Andrew M. Prentice, David Jeffries, Umbe Source Type: research
The household economic burden of drug-susceptible TB diagnosis and treatment in The Gambia
(Source: International Journal of Tuberculosis and Lung Disease)
Source: International Journal of Tuberculosis and Lung Disease - December 1, 2022 Category: Respiratory Medicine Authors: Devoid, I. Sillah, A. K. Sutherland, J. Owolabi, O. Ivanova, O. Govathson, C. Hirasen, K. Davies, M. L önnroth, K. Loum, I. Touray, A. Charlambous, S. Evans, D. Quaife, M. Tags: ORIGINAL ARTICLES Source Type: research
Prevention of young infant infections using oral azithromycin in labour in Fiji (Bulabula MaPei): study protocol of a randomised control trial
Introduction
Infections are a leading cause of neonatal mortality globally and can be transmitted from mother-to-child vertically or horizontally. Fiji has higher rates of serious neonatal infections and infant skin and soft tissue infections (SSTIs) than high-income countries. Research from the Gambia found that a single dose of oral azithromycin in labour decreased bacterial carriage and infections in mothers and infants, particularly infant skin infections. The Bulabula MaPei clinical trial evaluates the safety and efficacy of a single dose of azithromycin in labour in reducing the incidence of maternal and infant SSTIs...
Source: BMJ Open - December 1, 2022 Category: General Medicine Authors: Hume-Nixon, M., Ratu, T., Clark, S., Nguyen, C. D., Neal, E. F. G., Pell, C. L., Bright, K., Watts, E., Hart, J., Mulholland, K., Fong, J., Rafai, E., Sakumeni, K., Tuibeqa, I., Satzke, C., Steer, A., Russell, F. M. Tags: Open access, Paediatrics Source Type: research
Gastrointestinal, vaginal, nasopharyngeal, and breast milk microbiota profiles and breast milk metabolomic changes in Gambian infants over the first two months of lactation: A prospective cohort study
This study’s results indicate that infant gut and respiratory microbiota are unique bacterial communities, distinct from maternal gut and breast milk, respectively. Breast milk microbiota composition and metabolomic profile change throughout lactation. These changes may contribute to the infant’s immunological, metabolic, and neurological development and could consist the basis for future interventions to correct disrupted early life microbial colonization. (Source: Medicine)
Source: Medicine - November 18, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Mac-2 binding protein glycosylation isomer (M2BPGi) to evaluate liver fibrosis and cancer in HBV-infected patients in West Africa
CONCLUSIONS: To the best of our knowledge, this is the first evaluation of M2BPGi in HBV-infected African population. The findings supported its accuracy in the diagnosis of cirrhosis in HBV-infected patients in West Africa.PMID:36370422 | DOI:10.7189/jogh.12.04076 (Source: Cancer Control)
Source: Cancer Control - November 12, 2022 Category: Cancer & Oncology Authors: Jeanne Perp étue Vincent Gibril Ndow Shintaro Ogawa Amie Ceesay Ramou Njie Bakary Sanneh Ignatius Baldeh Umberto D'Alessandro Maimuna Mendy Mark Thursz Isabelle Chemin Yasuhito Tanaka Maud Lemoine Yusuke Shimakawa Source Type: research
Longitudinal Change in Bone Density, Geometry, and Estimated Bone Strength in Older Men and Women From The Gambia: Findings From the Gambian Bone and Muscle Aging Study (GamBAS)
ABSTRACTMusculoskeletal aging in the most resource-limited countries has not been quantified, and longitudinal data are urgently needed to inform policy. The aim of this prospective study was to describe musculoskeletal aging in Gambian adults. A total of 488 participants were recruited stratified by sex and 5-year age band (aged 40 years and older); 386 attended follow-up 1.7 years later. Outcomes were dual-energy X-ray absorptiometry (DXA) (n = 383) total hip areal bone mineral density (aBMD), bone mineral content (BMC), bone area (BA); peripheral quantitative computed tomography (pQCT) diaphyseal and epiphyseal r...
Source: Journal of Bone and Mineral Research - November 12, 2022 Category: Orthopaedics Authors: M ícheál Ó Breasail,
Camille Pearse,
Ayse Zengin,
Landing Jarjou,
Cyrus Cooper,
Peter R Ebeling,
Ann Prentice,
Kate A Ward Tags: RESEARCH ARTICLE Source Type: research
Anaemia and its determinants among reproductive age women (15 –49 years) in the Gambia: a multi-level analysis of 2019–20 Gambian Demographic and Health Survey Data
ConclusionThe study revealed that the burden of anaemia among reproductive age Gambian women was very high. Anaemia was affected by both individual and community levels of factors. Thus, the burden of anaemia could be significantly reduced if pregnant and contraceptive users' women were monitored and encouraged. Increasing the accessibility of health facilities, community mobilization, and awareness enhancement are also advisable. (Source: Archives of Public Health)
Source: Archives of Public Health - November 9, 2022 Category: International Medicine & Public Health Source Type: research
Effect of price on the decision to experiment with cigarette smoking among Gambian children: a survival analysis using the Gambia 2017 Global Youth Tobacco Survey data
Conclusion
There is strong evidence that increasing excise taxes can play an effective role in discouraging children from experimenting with cigarette smoking. Considering the relatively low excise tax burden in the Gambia, the government should consider substantially increasing the excise tax burden. (Source: BMJ Open)
Source: BMJ Open - November 8, 2022 Category: General Medicine Authors: Dare, C., Cham, B., Boachie, M. K., Gitonga, Z., D'Alessandro, U., Walbeek, C. Tags: Open access, Smoking and tobacco Source Type: research
Sequence based HLA-DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in The Gambia
Hum Immunol. 2022 Nov 2:S0198-8859(22)00226-9. doi: 10.1016/j.humimm.2022.10.009. Online ahead of print.ABSTRACTClass II HLA loci DRB1, DQB1 and DPB1 were typed for a total of 939 Gambian participants by locus-specific amplicon sequencing. Participants were from multiple regions of The Gambia and drawn from two studies: a family study aiming to identify associations between host genotype and trachomatous scarring (N = 796) and a cohort study aiming to identify correlates of immunity to trachoma (N = 143). All loci deviated from Hardy-Weinberg equilibrium, likely due to the family-based nature of the study: 608 participants...
Source: Human Immunology - November 5, 2022 Category: Allergy & Immunology Authors: Amber Barton Harry Pickering Thomas Payne Nkoyo Faal Ansumana Sillah Anna Harte Robin L Bailey David C W Mabey Chrissy H Roberts Martin J Holland Source Type: research
