Global pediatric anesthesia-Anglophone West Africa perspective
This article gives the pediatric anesthesia perspective from Cameroon, Nigeria, Ghana, Liberia, and Gambia, five out of six countries in Anglophone West Africa. Over 40% of the population of most of these countries are younger than 14 years and there is an increasing need for paediatric anesthesia services.FINDINGS: Workforce density ranges from 0.08 to 0.58 physician anesthesia providers per 100,000 population. There are only 13 trained pediatric anesthetists; ratios range from 0 to 0.4 per 100,000 children, thus pediatric anesthesia services are provided by various cadres of physician and non-physician anesthesia provide...
Source: Pain Physician - February 7, 2024 Category: Anesthesiology Authors: Ibironke Desalu Pokua Sarpong Maryrose O Osazuwa Raymond Ndikontar Kwinji Aramide Folayemi Faponle Musa Kallamu Suleiman Junette Metogo Mbengono Epse Njoki Iniabasi Ilori Olayinka R Eyelade Anastasia Abena Ohene Audrey Anno William Addison Source Type: research

Global pediatric anesthesia-Anglophone West Africa perspective
This article gives the pediatric anesthesia perspective from Cameroon, Nigeria, Ghana, Liberia, and Gambia, five out of six countries in Anglophone West Africa. Over 40% of the population of most of these countries are younger than 14 years and there is an increasing need for paediatric anesthesia services.FINDINGS: Workforce density ranges from 0.08 to 0.58 physician anesthesia providers per 100,000 population. There are only 13 trained pediatric anesthetists; ratios range from 0 to 0.4 per 100,000 children, thus pediatric anesthesia services are provided by various cadres of physician and non-physician anesthesia provide...
Source: Paediatric Anaesthesia - February 7, 2024 Category: Anesthesiology Authors: Ibironke Desalu Pokua Sarpong Maryrose O Osazuwa Raymond Ndikontar Kwinji Aramide Folayemi Faponle Musa Kallamu Suleiman Junette Metogo Mbengono Epse Njoki Iniabasi Ilori Olayinka R Eyelade Anastasia Abena Ohene Audrey Anno William Addison Source Type: research

Asymptomatic Plasmodium falciparum carriage at the end of the dry season is associated with subsequent infection and clinical malaria in Eastern Gambia
Chronic carriage of asymptomatic low-density Plasmodium falciparum parasitaemia in the dry season may support maintenance of acquired immunity that protects against clinical malaria. However, the relationship bet... (Source: Malaria Journal)
Source: Malaria Journal - January 17, 2024 Category: Infectious Diseases Authors: Balotin Fogang, Lionel Lellouche, Sukai Ceesay, Sainabou Drammeh, Fatou K. Jaiteh, Marc-Antoine Guery, Jordi Landier, Cynthia P. Haanappel, Janeri Froberg, David Conway, Umberto D ’Alessandro, Teun Bousema and Antoine Claessens Tags: Research Source Type: research

The impact of prior SARS-CoV-2 infection on host inflammatory cytokine profiles in patients with TB or other respiratory diseases
ConclusionsOur findings demonstrate that COVID-19 infection alters the subsequent response to TB and ORDs, potentially contributing to pathogenesis. Further work is necessary to determine whether COVID-19 infection accelerates TB disease progression, though our results experimentally support this hypothesis. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - December 21, 2023 Category: Allergy & Immunology Source Type: research

Capacity assessment and spatial analysis of cervical cancer services in The Gambia
Cervical cancer is the most common cancer and the leading cause of cancer-related death in Gambian women. The Gambian Ministry of Health is striving to improve access to screening, diagnostic, and treatment se... (Source: BMC Women's Health)
Source: BMC Women's Health - December 9, 2023 Category: OBGYN Authors: Meghan E. Mali, Ousman Sanyang, Katherine L. Harris, Justin Sorensen, Mustapha Bittaye, Jonathan Nellermoe, Raymond R. Price and Edward K. Sutherland Tags: Research Source Type: research

Trend and determinants of home delivery in Gambia, evidence from 2013 and 2020 Gambia Demographic and Health Survey: A multivariate decomposition analysis
by Solomon Gedlu Nigatu BackgroundHome delivery is defined as is an even of pregnant women getting giving birth in a woman her home or other homes without an unskilled health professional assistance. It is continuing as public health problem since its responsible for death of women and newborn. In Gambia there is a high maternal mortality rate, which may be related to home delivery. Therefore, this study aimed to assess the trend of home delivery and identify predictors using Gambia Demographic and Health Survey (GDHS) 2013 and 2019 –2020 data sets. MethodsA Cross-Section survey was conducted based on GDHS 2013 and 2019 ...
Source: PLoS One - December 6, 2023 Category: Biomedical Science Authors: Solomon Gedlu Nigatu Source Type: research

Prevalence and factors associated with occupational injuries among building construction workers in the Gambia
Conclusion Our findings show that injuries among building construction workers are prevalent in the Gambia. Male gender, work hours, tobacco use and alcohol consumption were associated with occupational injuries in building construction. Introducing and enforcing workplace safety policies in the building construction industry may help reduce occupational injury among construction workers in the Gambia. (Source: Injury Prevention)
Source: Injury Prevention - November 27, 2023 Category: Accident Prevention Authors: Kinteh, B., Bass, P. Tags: Open access Original research Source Type: research

Missed opportunities for vaccination at point of care and their impact on coverage and urban-rural coverage inequity in the Gambia
CONCLUSION: Our study highlights the prevalence and negative impact of MOSVs on overall vaccination coverage. Although MOSVs did not contribute significantly to the total urban-rural inequity in coverage, they have detrimental effects on vaccination coverage and urban-rural inequity among children who had experienced MOSVs. Addressing MOSVs, can enhance coverage and reduce the risk of under-vaccination, aligning with global initiatives.PMID:37996292 | DOI:10.1016/j.vaccine.2023.11.041 (Source: Vaccine)
Source: Vaccine - November 23, 2023 Category: Allergy & Immunology Authors: Alieu Sowe Fredinah Namatovu Bai Cham Per E Gustafsson Source Type: research

Missed opportunities for vaccination at point of care and their impact on coverage and urban-rural coverage inequity in the Gambia
CONCLUSION: Our study highlights the prevalence and negative impact of MOSVs on overall vaccination coverage. Although MOSVs did not contribute significantly to the total urban-rural inequity in coverage, they have detrimental effects on vaccination coverage and urban-rural inequity among children who had experienced MOSVs. Addressing MOSVs, can enhance coverage and reduce the risk of under-vaccination, aligning with global initiatives.PMID:37996292 | DOI:10.1016/j.vaccine.2023.11.041 (Source: Vaccine)
Source: Vaccine - November 23, 2023 Category: Allergy & Immunology Authors: Alieu Sowe Fredinah Namatovu Bai Cham Per E Gustafsson Source Type: research

Association between women ’s experience of domestic violence and childhood vaccination in West Africa: Cross-sectional analysis of Demographic and Health Survey data
ConclusionsThere was no significant association between a woman ’s exposure to domestic violence and whether her child was fully vaccinated. Further work is needed to understand the contextual factors which may explain potential variations between countries. (Source: PLoS One)
Source: PLoS One - November 2, 2023 Category: Biomedical Science Authors: Toluwalogo Daramola Source Type: research

Antibiotics susceptibility patterns of uropathogenic bacteria: a cross-sectional analytic study at Kanifing General Hospital, The Gambia
This study determined the susceptibility patterns of uropathogens and associated risk fac... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - October 25, 2023 Category: Infectious Diseases Authors: Abou Kebbeh, Paul Dsane-Aidoo, Kawsu Sanyang, Sheriffo M. K. Darboe, Nuha Fofana, Donne Ameme, Abdoulie M. Sanyang, Kalifa Sanneh Darboe, Saffiatou Darboe, Bakary Sanneh, Ernest Kenu and Francis Anto Tags: Research Source Type: research

Longitudinal changes in tear cytokines and antimicrobial proteins in trachomatous disease
ConclusionsThese findings suggest that the ocular immune system responds prior to and continues to respond after detectableC.trachomatis infection, possibly due to a positive feedback loop inducing immune activation. Levels of CXC chemokines in successive infection episodes were increased, which may offer an explanation as to why repeated infections are a risk factor for scarring. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - October 20, 2023 Category: Tropical Medicine Authors: Amber Barton Source Type: research

Childhood TB sequel: evaluating respiratory function after treatment for pulmonary tuberculosis in a prospective cohort of Gambian children – a study protocol
1.2 million children under 15 years are estimated to have developed tuberculosis (TB) in 2021. 85% of paediatric patients achieve successful treatment outcomes if treated for the first episode of TB. However, ... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - October 12, 2023 Category: Respiratory Medicine Authors: Esin Nkereuwem, Schadrac Agbla, Muhammed Lamin Jatta, Uma Masterton, Olumuyiwa Owolabi, Victory Fabian Edem, Beate Kampmann and Toyin Togun Tags: Study Protocol Source Type: research

Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of < em > P. falciparum < /em > uncomplicated malaria in African pregnant women (PYRAPREG): study protocol for a phase 3, non-inferiority, randomised open-label clinical trial
BMJ Open. 2023 Oct 9;13(10):e065295. doi: 10.1136/bmjopen-2022-065295.ABSTRACTINTRODUCTION: Malaria infection during pregnancy increases the risk of low birth weight and infant mortality and should be prevented and treated. Artemisinin-based combination treatments are generally well tolerated, safe and effective; the most used being artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP). Pyronaridine-artesunate (PA) is a new artemisinin-based combination. The main objective of this study is to determine the efficacy and safety of PA versus AL or DP when administered to pregnant women with confirmed Plasmodium...
Source: Cancer Control - October 9, 2023 Category: Cancer & Oncology Authors: Moussa Djimde Japhet Kabalu Tshiongo Hypolite Mavoko Muhindo Halidou Tinto Esperanca Sevene Maminata Traore Anifa Vala Salesio Macuacua Berenger Kabore Edgard Diniba Dabira Annette Erhart Hamadoun Diakite Mohamed Keita Mireia Piqueras Raquel Gonz ález Cl Source Type: research

Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of P. falciparum uncomplicated malaria in African pregnant women (PYRAPREG): study protocol for a phase 3, non-inferiority, randomised open-label clinical trial
Introduction Malaria infection during pregnancy increases the risk of low birth weight and infant mortality and should be prevented and treated. Artemisinin-based combination treatments are generally well tolerated, safe and effective; the most used being artemether-lumefantrine (AL) and dihydroartemisinin-piperaquine (DP). Pyronaridine-artesunate (PA) is a new artemisinin-based combination. The main objective of this study is to determine the efficacy and safety of PA versus AL or DP when administered to pregnant women with confirmed Plasmodium falciparum infection in the second or third trimester. The primary hypothesis ...
Source: BMJ Open - October 9, 2023 Category: General Medicine Authors: Djimde, M., Tshiongo, J. K., Muhindo, H. M., Tinto, H., Sevene, E., Traore, M., Vala, A., Macuacua, S., Kabore, B., Dabira, E. D., Erhart, A., Diakite, H., Keita, M., Piqueras, M., Gonzalez, R., Menendez, C., Dorlo, T. P., Sagara, I., Mens, P., Schallig, Tags: Open access, Epidemiology Source Type: research