Viruses, Vol. 16, Pages 455: Acalculous Cholecystitis in COVID-19 Patients: A Narrative Review
stos Savopoulos Acute acalculous cholecystitis (AAC) represents cholecystitis without gallstones, occurring in approximately 5–10% of all cases of acute cholecystitis in adults. Several risk factors have been recognized, while infectious diseases can be a cause of cholecystitis in otherwise healthy people. Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has spread worldwide, leading to an unprecedented pandemic. The virus enters cells through the binding of the spike protein to angiotensin-converting enzyme 2 (ACE2) receptors expressed ...
Source: Viruses - March 15, 2024 Category: Virology Authors: Evanthia Thomaidou Eleni Karlafti Matthaios Didagelos Kalliopi Megari Eleni Argiriadou Karolina Akinosoglou Daniel Paramythiotis Christos Savopoulos Tags: Review Source Type: research

Independent association of general and central adiposity with risk of gallstone disease: observational and genetic analyses
ConclusionBoth observational and genetic analyses consistently provide evidence on an association of central obesity with an increased risk of GSD, independent of general obesity. Our work highlights the need of considering both general and central obesity in the clinical management of GSD. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 11, 2024 Category: Endocrinology Source Type: research

Like a Rolling (Gall)Stone: Optimal Treatment of Gallstone Obstruction of the Sigmoid Colon
ConclusionA multidisciplinary discussion between endoscopists and surgeons is often needed to choose the best therapeutic option, especially in high-risk patients. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 11, 2024 Category: Gastroenterology Source Type: research

Gallbladder microbial species and host bile acids biosynthesis linked to cholesterol gallstone comparing to pigment individuals
Gallstones are crystalline deposits in the gallbladder that are traditionally classified as cholesterol, pigment, or mixed stones based on their composition. Microbiota and host metabolism variances among the different types of gallstones remain largely unclear. Here, the bile and gallstone microbial species spectra of 29 subjects with gallstone disease (GSD, 24 cholesterol and 5 pigment) were revealed by type IIB restriction site-associated DNA microbiome sequencing (2bRAD-M). Among them (21 subjects: 18 cholesterol and 3 pigment), plasma samples were subjected to liquid chromatography–mass spectrometry (LC-MS) untarget...
Source: Frontiers in cellular and infection microbiology - March 11, 2024 Category: Microbiology Source Type: research

Like a Rolling (Gall)Stone: Optimal Treatment of Gallstone Obstruction of the Sigmoid Colon
ConclusionA multidisciplinary discussion between endoscopists and surgeons is often needed to choose the best therapeutic option, especially in high-risk patients. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - March 11, 2024 Category: Gastroenterology Source Type: research

Comparison of laparoscopic cholecystectomy in children at paediatric centres and adult centres: a systematic review and meta-analysis
CONCLUSIONS: The number of LCs performed, intraoperative cholangiography use and conversion rates were higher at ACs whereas bile duct injury and reoperation rates were higher at PCs. Despite a higher incidence of bile duct injury at PCs, the incidence at both PCs and ACs was <1%. In complex cases, a joint operation by both paediatric and adult surgeons might be a better approach to further improve outcomes. Overall, LC was found to be a safe operation with comparable outcomes at PCs and ACs.PMID:38445605 | DOI:10.1308/rcsann.2023.0041 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: A Sinha A Mattson I Njere C K Sinha Source Type: research

Comparison of laparoscopic cholecystectomy in children at paediatric centres and adult centres: a systematic review and meta-analysis
CONCLUSIONS: The number of LCs performed, intraoperative cholangiography use and conversion rates were higher at ACs whereas bile duct injury and reoperation rates were higher at PCs. Despite a higher incidence of bile duct injury at PCs, the incidence at both PCs and ACs was <1%. In complex cases, a joint operation by both paediatric and adult surgeons might be a better approach to further improve outcomes. Overall, LC was found to be a safe operation with comparable outcomes at PCs and ACs.PMID:38445605 | DOI:10.1308/rcsann.2023.0041 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: A Sinha A Mattson I Njere C K Sinha Source Type: research

Comparison of laparoscopic cholecystectomy in children at paediatric centres and adult centres: a systematic review and meta-analysis
CONCLUSIONS: The number of LCs performed, intraoperative cholangiography use and conversion rates were higher at ACs whereas bile duct injury and reoperation rates were higher at PCs. Despite a higher incidence of bile duct injury at PCs, the incidence at both PCs and ACs was <1%. In complex cases, a joint operation by both paediatric and adult surgeons might be a better approach to further improve outcomes. Overall, LC was found to be a safe operation with comparable outcomes at PCs and ACs.PMID:38445605 | DOI:10.1308/rcsann.2023.0041 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: A Sinha A Mattson I Njere C K Sinha Source Type: research

Comparison of laparoscopic cholecystectomy in children at paediatric centres and adult centres: a systematic review and meta-analysis
CONCLUSIONS: The number of LCs performed, intraoperative cholangiography use and conversion rates were higher at ACs whereas bile duct injury and reoperation rates were higher at PCs. Despite a higher incidence of bile duct injury at PCs, the incidence at both PCs and ACs was <1%. In complex cases, a joint operation by both paediatric and adult surgeons might be a better approach to further improve outcomes. Overall, LC was found to be a safe operation with comparable outcomes at PCs and ACs.PMID:38445605 | DOI:10.1308/rcsann.2023.0041 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: A Sinha A Mattson I Njere C K Sinha Source Type: research

Comparison of laparoscopic cholecystectomy in children at paediatric centres and adult centres: a systematic review and meta-analysis
CONCLUSIONS: The number of LCs performed, intraoperative cholangiography use and conversion rates were higher at ACs whereas bile duct injury and reoperation rates were higher at PCs. Despite a higher incidence of bile duct injury at PCs, the incidence at both PCs and ACs was <1%. In complex cases, a joint operation by both paediatric and adult surgeons might be a better approach to further improve outcomes. Overall, LC was found to be a safe operation with comparable outcomes at PCs and ACs.PMID:38445605 | DOI:10.1308/rcsann.2023.0041 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: A Sinha A Mattson I Njere C K Sinha Source Type: research

Comparison of laparoscopic cholecystectomy in children at paediatric centres and adult centres: a systematic review and meta-analysis
CONCLUSIONS: The number of LCs performed, intraoperative cholangiography use and conversion rates were higher at ACs whereas bile duct injury and reoperation rates were higher at PCs. Despite a higher incidence of bile duct injury at PCs, the incidence at both PCs and ACs was <1%. In complex cases, a joint operation by both paediatric and adult surgeons might be a better approach to further improve outcomes. Overall, LC was found to be a safe operation with comparable outcomes at PCs and ACs.PMID:38445605 | DOI:10.1308/rcsann.2023.0041 (Source: Annals of the Royal College of Surgeons of England)
Source: Annals of the Royal College of Surgeons of England - March 6, 2024 Category: Surgery Authors: A Sinha A Mattson I Njere C K Sinha Source Type: research

Methylation changes of liver DNA during the formation of gallstones
Epigenomics, Ahead of Print. (Source: Future Medicine: Epigenomics)
Source: Future Medicine: Epigenomics - March 6, 2024 Category: Genetics & Stem Cells Authors: Junbin Peng Haojie Li Fang Tong Jinlong Hu Min Li Gan Chen Dongquan Liu Jinshan Liu Rui Wang Hongyu Xu Xuanxuan Li Xinguo Zhong Jiaming Yao Baoqiang Cao Source Type: research

Therapeutic plasma exchange decreases serum triglyceride level rapidly and reduces early recurrence rate but no advantages in improving outcomes for patients with hyperlipidemic acute pancreatitis: a retrospective propensity score matching analysis based on twenty year ’s experience
Hyperlipidaemic acute pancreatitis (HLAP) has become the most common cause of acute pancreatitis (AP) not due to gallstones or alcohol (Mosztbacher et al, Pancreatology 20:608-616, 2020; Yin et al, Pancreas 46... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - March 6, 2024 Category: Endocrinology Authors: Canbin Zheng, Yongping Zheng and Zihui Zheng Tags: Research Source Type: research

Increase in acute pancreatitis, especially gallstone related, as the cause for emergency admissions: Temporal trend from Kashmir, India
ConclusionThe incidence of acute pancreatitis is increasing due to gallstone pancreatitis. Ascariasis-related acute pancreatitis has declined. There is significant contribution of asymptomatic gallstones in patients who present for the first time as acute pancreatitis. Small gallstones  <  5 mm are likely to be the risk factors for gallstone pancreatitis.Graphical Abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - March 6, 2024 Category: Gastroenterology Source Type: research