Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research

Pathophysiology of severe gallstone pancreatitis: A new paradigm
World J Gastroenterol. 2024 Feb 21;30(7):614-623. doi: 10.3748/wjg.v30.i7.614.ABSTRACTSevere gallstone pancreatitis (GSP) refractory to maximum conservative therapy has wide clinical variations, and its pathophysiology remains controversial. This Editorial aimed to investigate the pathophysiology of severe disease based on Opie's theories of obstruction, the common channel, and duodenal reflux and describe its types. Severe GSP might be a hybrid disease with pathology polarized between acute cholangitis with mild pancreatitis (biliary type) and necrotizing pancreatitis uncomplicated with biliary tract disease (pancreatic t...
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Masatoshi Isogai Source Type: research