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Lyrica vs. Gabapentin: Which Is Better for Pain?
Title: Lyrica vs. Gabapentin: Which Is Better for Pain?Category: MedicationsCreated: 10/31/2017 12:00:00 AMLast Editorial Review: 10/31/2017 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - October 31, 2017 Category: Endocrinology Source Type: news

Lyrica vs. Gabapentin: Differences between Pain Relief and Uses
Title: Lyrica vs. Gabapentin: Differences between Pain Relief and UsesCategory: MedicationsCreated: 10/31/2017 12:00:00 AMLast Editorial Review: 10/31/2017 12:00:00 AM (Source: MedicineNet Diabetes General)
Source: MedicineNet Diabetes General - October 31, 2017 Category: Endocrinology Source Type: news

Drug safety update: Gabapentin (Neurontin): risk of severe respiratory depression
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update for Gabapentin... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - October 27, 2017 Category: Drugs & Pharmacology Source Type: news

Gabapentin Plus Opioids a Deadly Combination? Gabapentin Plus Opioids a Deadly Combination?
The risk for opioid-related death was 49% higher in patients recently exposed to gabapentin and opioids compared to those exposed to opioids alone.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 4, 2017 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Combined use of opioids and gabapentin substantially increases risk of overdose
(Source: St. Michael's Hospital News and Media)
Source: St. Michael's Hospital News and Media - October 3, 2017 Category: Hospital Management Tags: Hospital News Source Type: news

Gabapentin co-use may increase risk of fatal opioid overdose
(PLOS) Co-prescription of the anticonvulsant gabapentin is associated with an increased risk of opioid-related death in people who are prescribed opioid painkillers, according to a new study published in PLOS Medicine. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 3, 2017 Category: Biology Source Type: news

New Reports Show Rising Gabapentin Misuse and Abuse
Recent studies show increasing misuse of gabapentin, with prevalence as high as 68% among those with opioid use disorders. Novus Medical Detox Center urges the DEA and FDA to classify the drug as a...(PRWeb August 21, 2017)Read the full story at http://www.prweb.com/releases/2017/08/prweb14616314.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - August 21, 2017 Category: Pharmaceuticals Source Type: news

Gabapentinoids Ineffective for Chronic Low Back Pain Gabapentinoids Ineffective for Chronic Low Back Pain
The gabapentinoids pregabalin and gabapentin are not effective in treating chronic low back pain (CLBP), according to a systematic review and meta-analysis.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 16, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Scientists discover powerful potential pain reliever
(University of Texas at Austin) Chemists have discovered a powerful pain reliever that acts on a previously unknown pain pathway. The compound is as effective at relieving neuropathic pain in injured mice as a drug widely used for pain relief called gabapentin. If they can demonstrate that it is safe, effective and nonaddictive in humans -- a process that typically takes years -- the discovery could address one of today's biggest public health challenges: the opioid abuse epidemic. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 16, 2017 Category: International Medicine & Public Health Source Type: news

Your NEJM Group Today: Concerns About Gabapentin for Pain / PPIs & Dementia / California IM Opportunity (FREE)
By the Editors Take a look at today's offering from NEJM Group:NEJM Audio Interview: Treating Pain with Gabapentinoids: Dr. … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - August 3, 2017 Category: Primary Care Source Type: news

Gabapentin and Postoperative Respiratory Depression Gabapentin and Postoperative Respiratory Depression
When included in multimodal analgesic regimens, is gabapentin associated with respiratory depression during post-anesthesia recovery after major laparoscopic procedures?Anesthesia & Analgesia (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 27, 2017 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Morning Break: Opioid-Neurontin Cocktails; Keytruda Trial Deaths
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - July 6, 2017 Category: Psychiatry Source Type: news

miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes
Nociception is protective and prevents tissue damage but can also facilitate chronic pain. Whether a general principle governs these two types of pain is unknown. Here, we show that both basal mechanical and neuropathic pain are controlled by the microRNA-183 (miR-183) cluster in mice. This single cluster controls more than 80% of neuropathic pain–regulated genes and scales basal mechanical sensitivity and mechanical allodynia by regulating auxiliary voltage-gated calcium channel subunits α2-1 and α2-2. Basal sensitivity is controlled in nociceptors, and allodynia involves TrkB+ light-touch mechanorecepto...
Source: ScienceNOW - June 15, 2017 Category: Science Authors: Peng, C., Li, L., Zhang, M.-D., Bengtsson Gonzales, C., Parisien, M., Belfer, I., Usoskin, D., Abdo, H., Furlan, A., Häring, M., Lallemend, F., Harkany, T., Diatchenko, L., Hökfelt, T., Hjerling-Leffler, J., Ernfors, P. Tags: Neuroscience reports Source Type: news

Law enforcement-derived data on gabapentin diversion and misuse, 2002-2015: diversion rates and qualitative research findings - Buttram ME, Kurtz SP, Dart RC, Margolin ZR.
PURPOSE: Recent limited epidemiologic and case reports suggest that gabapentin is being misused, especially among prescription opioid misusers. However, no apparent studies have reported data from law enforcement on the diversion and misuse of gabapentin. ... (Source: SafetyLit)
Source: SafetyLit - May 19, 2017 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Dangers of mixing heroin and commonly prescribed non-opioid pain killers
A multi-disciplinary study has shown that the recent substantial increase in prescriptions for two drugs, pregabalin and gabapentin, used widely for a range of neurological disorders is closely correlated with a rise in the number of overdose deaths in England and Wales. (Source: NHS Networks)
Source: NHS Networks - May 15, 2017 Category: UK Health Source Type: news

Combining heroin and commonly prescribed non-opioid pain killers leads to a significant rise in overdose deaths
A multi-disciplinary study has shown that the recent substantial increase in prescriptions for two drugs, pregabalin and gabapentin, used widely for a range of neurological disorders is closely correlated with a rise in the number of overdose deaths in England and Wales. These drugs have become drugs of abuse, according to new University of Bristol findings published in Addiction, which highlight that they are especially dangerous when used with heroin or other opioids (Source: University of Bristol news)
Source: University of Bristol news - May 11, 2017 Category: Universities & Medical Training Tags: International, Health, Research; Faculty of Health Sciences, School of Social and Community Medicine, Faculty of Health Sciences; Press Release Source Type: news

Combining heroin and commonly prescribed non-opioid pain killers leads to a significant rise in over
(University of Bristol) A multi-disciplinary study has shown that the recent substantial increase in prescriptions for two drugs, pregabalin and gabapentin, used widely for a range of neurological disorders is closely correlated with a rise in the number of overdose deaths in England and Wales. These drugs have become drugs of abuse, according to new University of Bristol findings published in Addiction, which highlight that they are especially dangerous when used with heroin or other opioids. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 11, 2017 Category: International Medicine & Public Health Source Type: news

Saying Nighty-Night to Breast Cancer Sleep Disturbance Saying Nighty-Night to Breast Cancer Sleep Disturbance
Acupuncture improved sleep better than did gabapentin in breast cancer survivors with hot flashes.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 2, 2016 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

The CDC Weighs in with Opioid Prescribing Guidelines
After months of sending mixed messages on the role of emergency medicine in stemming the tide of opioid abuse, the CDC has published guidelines that could prove useful in the emergency department. Opioid abuse is no longer merely a topic for medical discussion. It has become a public health concern of the highest magnitude, even making its way into the speeches of this year’s presidential candidates. The numbers speak for themselves, justifying the concern. Over 10 million Americans reported nonmedical use of prescription opioids in 2014. Visits to the emergency department (ED) for misuse or abuse of prescription o...
Source: EPMonthly.com - November 21, 2016 Category: Emergency Medicine Authors: Matt McGahen Tags: Uncategorized Source Type: news

N.J.-based Amneal Pharmaceuticals could sell for as much as $8 billion
Swiss drug company Novartis AG is nearing an agreement to buy New Jersey-based Amneal Pharmaceuticals for $8 billion. There has not been a decision yet as Amneal could potentially be a target for other suitors, according to Bloomberg News, citing anonymous sources. Amneal, based in Bridgewater, is known for making numerous generic medicines, including gabapentin for epilepsy and pain, and acyclovir, a treatment for herpes as well as. A family-owned business since it was founded in 2002, Amneal… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 14, 2016 Category: Biotechnology Authors: Anthony Noto Source Type: news

gabapentin (Neurontin, Gralise, Horizant, Fanatrex FusePag)
Title: gabapentin (Neurontin, Gralise, Horizant, Fanatrex FusePag)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 11/11/2016 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - November 11, 2016 Category: Drugs & Pharmacology Source Type: news

Lower PNP costs with pregabalin vs gabapentin in Spain
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - October 31, 2016 Category: Drugs & Pharmacology Source Type: news

Neurontin (Gabapentin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 26, 2016 Category: Drugs & Pharmacology Source Type: news

1 in 5 opioid users also might be abusing seizure drug: Study
HealthDay News Opioid medication users may be abusing and misusing the seizure and nerve pain drug gabapentin, a new study finds. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 3, 2016 Category: Consumer Health News Source Type: news

1 in 5 Opioid Users Also Might Be Abusing Seizure Drug: Study
WEDNESDAY, Aug. 3, 2016 -- Opioid medication users may be abusing and misusing the seizure and nerve pain drug gabapentin, a new study finds. Researchers looked at test results of 323 patients who were prescribed opioid pain medications. The... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 3, 2016 Category: Journals (General) Source Type: news

A decade of gabapentinoid misuse: an analysis of the European Medicines Agency's 'Suspected Adverse Drug Reactions' Database - Chiappini S, Schifano F.
INTRODUCTION: The gabapentinoids pregabalin and gabapentin are being increasingly prescribed for a range of clinical conditions. Recently, although gabapentinoids at therapeutic dosages may present with low addictive liability levels, cases of misuse and r... (Source: SafetyLit)
Source: SafetyLit - June 28, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Horizant (Gabapentin Enacarbil Extended-Release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 25, 2016 Category: Drugs & Pharmacology Source Type: news

Gabapentin Use in Postop and Neuropathic Pain in ChildrenGabapentin Use in Postop and Neuropathic Pain in Children
How safe and effective is gabapentin for neuropathic and postoperative pain management in children? Pediatric Pharmacotherapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 13, 2016 Category: Consumer Health News Tags: Pediatrics Journal Article Source Type: news

Gabapentin concentrations and postmortem distribution - Hamm CE, Gary RD, McIntyre IM.
Gabapentin is a widely prescribed medication used primarily for the treatment of epilepsy and neuropathic pain. Gabapentin has a favorable adverse effect profile in therapeutic dosing with the most common reported effects being dizziness, fatigue, drowsine... (Source: SafetyLit)
Source: SafetyLit - April 11, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Seizure drug Gabapentin lowers postoperative nausea and vomiting risk
The anticonvulsant medication gabapentin—already a useful part of strategies to control pain after surgery—also effectively reduces the common complication of postoperative nausea and vomiting (PONV), reports a study. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 23, 2016 Category: Science Source Type: news

What Are Some Medications for Anxiety?
Assorted medications somtimes used to treat anxiety - Buspar (buspirone), Neurontin (gabapentin), beta blockers Inderal (propranolol) (Source: About.com Mental Health)
Source: About.com Mental Health - February 28, 2016 Category: Psychiatry Tags: health Source Type: news

Gabapentin misuse, abuse, and diversion: a systematic review - Smith RV, Havens JR, Walsh SL.
Background and Aims Since its market release, gabapentin has been presumed to have no abuse potential and subsequently has been prescribed widely off-label, despite increasing reports of gabapentin misuse. This review estimates and describes the prevale... (Source: SafetyLit)
Source: SafetyLit - February 5, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Cure: A Journey Into the Science of Mind Over Body review – can illness be ‘all in your head’?
From placebos and ‘kissing it better’ to hypnosis and Lourdes – a level-headed look at alternatives to prescription drugsThere are certain kinds of illnesses that seem to cause great distress to doctors; and there are certain kinds of patients that medicine seems almost incapable of helping. It can seem to some people that doctors are almost hostile to them. We often read in illness memoirs of doctors who have been dismissive, and patients being told: “it’s all in your head”, “you’re imagining it”, “your symptoms aren’t real” (whatever that means).I ha...
Source: Guardian Unlimited Science - February 5, 2016 Category: Science Authors: Peter Dorward Tags: Science and nature Books Culture Society Source Type: news

5 Ways To Stop A Nagging Cough
SPECIAL FROM Holiday shopping. Holiday parties. Airplanes. It seems like wherever you go this time of year, you’re bound to find someone coughing on you. Ick. Next thing you know, you’re coughing, too. How to stop your nagging cough? We asked the experts. “Coughing is one of the most common reasons people visit their health care provider,” says Rachel Taliercio, D.O, a pulmonologist with the Respiratory Institute at the Cleveland Clinic. And there are a variety of diseases that cause people to cough. How you treat that cough depends on what’s causing it in the first place. That said, there ar...
Source: Healthy Living - The Huffington Post - December 24, 2015 Category: Consumer Health News Source Type: news

Gabapentin New Drug of Abuse?Gabapentin New Drug of Abuse?
The nonmedical use of gabapentin is on the rise, particularly among substance abuse patients in rehabilitation programs, researchers say. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 11, 2015 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Gabapentin Enacarbil Effective in Improving Severe RLS SymptomsGabapentin Enacarbil Effective in Improving Severe RLS Symptoms
Gabapentin enacarbil (GEn) improves restless leg syndrome (RLS) symptoms in patients with severe RLS, according to a new analysis of pooled data from three trials. Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 30, 2015 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

What Side Effects May Occur if I Take Neurontin?
Read about the possible common and serious side effects of the anti-seizure medication Neurontin used sometimes in the treatment of bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - November 24, 2015 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

I am Bipolar. Can I Take Neurontin and What are...
Read about the debatable role of Neurontin, or gabapentin, in treating bipolar disorder and basic facts, like its potential common side effects. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - November 12, 2015 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

What Are Treatments for Hiccups?
Discussion Hiccups affect nearly everyone at sometime in their life but continue to be poorly understood and are usually considered a nuisance. The medical term for hiccups is singultus which comes from the Latin meaning “to be caught in the act of sobbing.” Hiccups are caused by a diaphragmatic spasm that causes a sudden inhalation that is interrupted by the spasmodic closure of the glottis that produces the characteristic hiccup sound. The ‘hic’ in hiccup occurs 4-60 times/minute and in adults has no physiological purpose, but in fetuses may help train inspiratory muscles for respiration after de...
Source: PediatricEducation.org - October 19, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Hepatocyte Growth Factor Shows Benefit for Diabetic PainHepatocyte Growth Factor Shows Benefit for Diabetic Pain
The nonviral gene therapy shows higher efficacy in pain relief among patients not taking pregabalin or gabapentin. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 9, 2015 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

NIH's NIAAA initiates clinical trial of Horizant to treat alcohol use disorder
The US National Institutes of Health's (NIH) National Institute on Alcohol Abuse and Alcoholism (NIAAA) has initiated a clinical trial of Horizant (gabapentin enacarbil) extended-release tablets to treat patients with moderate to severe alcohol use d… (Source: Drug Development Technology)
Source: Drug Development Technology - June 25, 2015 Category: Pharmaceuticals Source Type: news

NIH begins clinical trial of new medication for alcohol use disorder
A clinical trial investigating a potential treatment for alcohol use disorder (AUD) was announced by the National Institute on Alcohol Abuse and Alcoholism (NIAAA). The study will assess the safety and efficacy of gabapentin enacarbil (HORIZANT) in extended-release tablets for treating moderate to severe AUD. NIAAA is part of the National Institutes of Health.   (Source: NIAAA News)
Source: NIAAA News - June 25, 2015 Category: Addiction Authors: groa Source Type: news

NIH begins clinical trial of new medication for alcohol use disorder
Study will assess the safety and efficacy of gabapentin enacarbil for treating moderate to severe AUD. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - June 25, 2015 Category: American Health Source Type: news

Neurontin side effects: How do I manage them?
(Source: MayoClinic.com - Ask a Specialist)
Source: MayoClinic.com - Ask a Specialist - June 24, 2015 Category: Consumer Health News Source Type: news

How Does Spinal Muscle Atrophy Present?
Discussion Muscle tone is the slight tension that is felt in a muscle when it is voluntarily relaxed. It can be assessed by asking the patient to relax and then taking the muscles through a range of motion such as moving the wrists, forearm and upper arm. Muscle strength is the muscle’s force against active resistance. Impaired strength is called weakness or paresis. There are 5 levels of muscle strength. Hypotonia can occur with or without weakness. Decreased fetal movements in utero, persistent hypotonia and difficulty feeding are more consistent with congenital rather than an acquired hypotonia. Common treatable c...
Source: PediatricEducation.org - June 22, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

My hysterectomy for cancer – Carol’s story
The post My hysterectomy for cancer – Carol’s story appeared first on Hysterectomy Association. In March 2013 I went for my routine annual smear, I have been on yearly smears since the birth of my last daughter in 1997. Two weeks later I received a letter with an appointment to attend the colposcopy clinic which was scheduled for two weeks later (end of April). I attended this and was told I had cin3 pre-cancer cells on my cervix. They tried to do the leep whilst I was there but were unable to do it as the pain was horrendous. So I was advised it needed to be done under a general. The end of May I had my l...
Source: The Hysterectomy Association - June 9, 2015 Category: OBGYN Authors: Linda Tags: Your Stories cancer cervical cancer Source Type: news

Non-controlled and over-the-counter drugs of abuse
  2.5 out of 5 stars Abuse of Medications That Theoretically Are Without Abuse Potential. Reeves RR et al. South Med J 2015 Mar;108:151-157. Abstract This review of noncontrolled prescription and over-the-counter drugs that can be and have been abused for non-medical or recreational purposes is rather sketchy and anecdotal (as the authors admit,) but nevertheless contains some useful information. Classes of drugs discussed include: Cold & Cough products: pseudoephedrine, ephedrine, oxymetazoline, dextromethorphan Anticholinergics: diphenhydramine, benztropine, trihexyphenidyl (Artane) Antipsychotics: quetiap...
Source: The Poison Review - March 24, 2015 Category: Toxicology Authors: Leon Tags: Medical cough/cold preparations dextromethorphan medication abuse otc over-the-counter Source Type: news

Aurobindo, Actavis recall Gabapentin capsules
The drug is manufactured by Aurobindo Pharma at its Mahabub Nagar facility in Andhra Pradesh. (Source: The Economic Times)
Source: The Economic Times - January 20, 2015 Category: Consumer Health News Source Type: news

Aurobindo Pharma's subsidiary recalls epilepsy drug in US
US-based unit of drug firm Aurobindo Pharma is voluntarily recalling a lot Gabapentin capsules, an anti-epilepsy drug, in the American market, as some empty capsules were found in certain batches. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - November 25, 2014 Category: Pharmaceuticals Source Type: news