Bacteria protect intestinal tumor model from being killed by immune cells
(Cell Press) Bacteria that are commonly found in the mouth are often abundant in patients with colon cancer, but the potential role these microbes play in tumor development has not been clear. A study published by Cell Press Feb. 18 in the journal Immunity reveals that the oral pathogen Fusobacterium nucleatum protects a variety of tumor cells from being killed by immune cells. The findings could open new avenues for the treatment of cancer in human patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 11, 2015 Category: Cancer & Oncology Source Type: news

A Case of Lemierre's Syndrome Caused by Initially Identified as Group C Streptococcus
We report a rare case of Lemierre's syndrome in a previously healthy 21-year-old male caused by Streptococcus anginosus, initially identified as a group C Streptococcus. The only other case of Lemierre's syndrome caused by group C Streptococcus may have been misidentified (1). (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - January 14, 2015 Category: Microbiology Authors: Diana Otero, Martin Gnoni, James W. Snyder, Forest W. Arnold Tags: Case Report Source Type: news

Multiplex Fluorescence In Situ Hybridization (M-FISH) and Confocal Laser Scanning Microscopy (CLSM) to Analyze Multispecies Oral Biofilms
Multiplex fluorescence in situ hybridization (M-FISH) constitutes a favorable microbiological method for the analysis of spatial distribution of highly variable phenotypes found in multispecies oral biofilms. The combined use of confocal laser scanning microscopy (CLSM) produces high-resolution three-dimensional (3D) images of individual bacteria in their natural environment. Here, we describe the application of M-FISH on early (Streptococcus spp., Actinomyces naeslundii) and late colonizers (Fusobacterium nucleatum, Veillonella spp.) of in situ-formed oral biofilms, the acquisition of CLSM images, as well as the qualitati...
Source: Springer protocols feed by Microbiology - March 27, 2014 Category: Microbiology Source Type: news

Key role for Fusobacterium adhesin in non-orthodontic periodontal inflammation
Researchers from China have found that patients with gingivitis and periodontitis are more likely to have Fusobacterium nucleatum carrying the novel Fusobacterium adhesin A than periodontally healthy people. (Source: MedWire News - Infectious Diseases)
Source: MedWire News - Infectious Diseases - January 31, 2014 Category: Infectious Diseases Source Type: news

Incidence, and Outcomes of Fusobacterium Species BacteremiaIncidence, and Outcomes of Fusobacterium Species Bacteremia
Fusobacterium are a rare cause of serious infection. What are the risk factors, incidence and outcomes of infection? BMC Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 18, 2013 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

A rare case of Lemierre's syndrome caused by methicillin-resistant Staphylococcus aureus in a facial abscess
Lemierre's syndrome, also known as postanginal sepsis, is characterized by unilateral jugular vein thrombosis; bacteremia, most often due to Fusobacterium necrophorum; and septic pulmonary emboli. Clinically, patients present with a severe sore throat, followed by fever and anterior cervical neck pain over the jugular vein. Most cases involve young healthy adults, but persons of any age may be affected. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 29, 2013 Category: Microbiology Authors: Joshua Rein, Sikhminder Sahansra, Anita Jose, Burke A. Cunha Source Type: news

What Are the Potential Complications of a Retropharyngeal Abscess?
Discussion Retropharyngeal abscesses (RPA) occur in the potential space bound anterior to the prevertebral fascia, posterior to the pharyngeal constrictor muscles and their fascia and laterally by the carotid sheaths and parapharyngeal space (another potential space lying laterally to the pharynx). The retropharyngeal potential space runs superiorally from the base of the skull to the mediastinum distally. It is the most common deep neck infection. In children under 4 years of age, retropharyngeal lymph nodes are present which regress after this age. RPA is most common in young children when these lymph nodes are present, ...
Source: PediatricEducation.org - May 27, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news